ATE197042T1 - Verfahren zur herstellung von enantiomerenreiner tetrahydrochinolincarbonsäure - Google Patents
Verfahren zur herstellung von enantiomerenreiner tetrahydrochinolincarbonsäureInfo
- Publication number
- ATE197042T1 ATE197042T1 AT97202305T AT97202305T ATE197042T1 AT E197042 T1 ATE197042 T1 AT E197042T1 AT 97202305 T AT97202305 T AT 97202305T AT 97202305 T AT97202305 T AT 97202305T AT E197042 T1 ATE197042 T1 AT E197042T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydrocinoline
- carbonic acid
- enantiomer pure
- producing enantiomer
- producing
- Prior art date
Links
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 2
- INRNDFZVAKDYFY-UHFFFAOYSA-N 1,2,3,4-tetrahydroquinoline-3-carboxylic acid Chemical compound C1=CC=C2CC(C(=O)O)CNC2=C1 INRNDFZVAKDYFY-UHFFFAOYSA-N 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 229940071870 hydroiodic acid Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 229960005190 phenylalanine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001607A IT1283640B1 (it) | 1996-07-29 | 1996-07-29 | Procedimento per la preparazione di un acido tetraidrochinolincarbossilico otticamente puro |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE197042T1 true ATE197042T1 (de) | 2000-11-15 |
Family
ID=11374693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97202305T ATE197042T1 (de) | 1996-07-29 | 1997-07-24 | Verfahren zur herstellung von enantiomerenreiner tetrahydrochinolincarbonsäure |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5905155A (de) |
| EP (1) | EP0823425B1 (de) |
| JP (1) | JPH1087630A (de) |
| AT (1) | ATE197042T1 (de) |
| DE (1) | DE69703323T2 (de) |
| ES (1) | ES2153157T3 (de) |
| IT (1) | IT1283640B1 (de) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256783A (en) * | 1991-09-18 | 1993-10-26 | Hoffmann-La Roche Inc. | Method for producing 2-isoquinoline compounds |
| EP0578163A1 (de) * | 1992-07-09 | 1994-01-12 | Hoechst Aktiengesellschaft | Verfahren zur Herstellung von D- bzw.L-bzw. D,L-1,2,3,4-Tetrahydroisochinolin-3-Carbonsäure |
| US5602255A (en) * | 1992-08-31 | 1997-02-11 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing tetrahydroisoquinoline-3-carboxylic acid compounds |
| WO1994005640A1 (fr) * | 1992-08-31 | 1994-03-17 | Kyowa Hakko Kogyo Co., Ltd. | Procede permettant de produire un derive d'acide tetrahydro-isoquinoline-3-carboxylique |
| US5610307A (en) * | 1995-03-14 | 1997-03-11 | The Nutra Sweet Company | Direct isolution of optically pure (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid |
| AU7724496A (en) * | 1995-11-09 | 1997-05-29 | Monsanto Company | An improved method for preparation of substituted tetrahydroisoquinolines |
| US5627282A (en) * | 1996-01-03 | 1997-05-06 | Yukong Limited | Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives |
-
1996
- 1996-07-29 IT IT96MI001607A patent/IT1283640B1/it active IP Right Grant
-
1997
- 1997-07-23 US US08/898,949 patent/US5905155A/en not_active Expired - Fee Related
- 1997-07-24 AT AT97202305T patent/ATE197042T1/de not_active IP Right Cessation
- 1997-07-24 ES ES97202305T patent/ES2153157T3/es not_active Expired - Lifetime
- 1997-07-24 EP EP97202305A patent/EP0823425B1/de not_active Expired - Lifetime
- 1997-07-24 DE DE69703323T patent/DE69703323T2/de not_active Expired - Fee Related
- 1997-07-29 JP JP9203082A patent/JPH1087630A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH1087630A (ja) | 1998-04-07 |
| EP0823425B1 (de) | 2000-10-18 |
| ITMI961607A1 (it) | 1998-01-29 |
| ES2153157T3 (es) | 2001-02-16 |
| EP0823425A1 (de) | 1998-02-11 |
| US5905155A (en) | 1999-05-18 |
| ITMI961607A0 (de) | 1996-07-29 |
| IT1283640B1 (it) | 1998-04-23 |
| DE69703323D1 (de) | 2000-11-23 |
| DE69703323T2 (de) | 2001-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |