ATE198196T1 - 2-hydroxy-3-(1-(1h-imidazol-4-yl)alkyl)-benzol carboximid-amide zur glaucoma-behandlung - Google Patents

2-hydroxy-3-(1-(1h-imidazol-4-yl)alkyl)-benzol carboximid-amide zur glaucoma-behandlung

Info

Publication number: ATE198196T1
Authority: AT; Austria
Prior art keywords: alkyl; hydroxy; imidazole; benzene; glaucoma treatment
Prior art date: 1993-05-27

Application number

AT94870084T

Other languages

English (en)

Inventor

Philippe Michel

Eric Cossement

Jean Gobert

Ernst Wuelfert

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-27

Filing date

1994-05-19

Publication date

2001-01-15

1994-05-19 Application filed by Ucb Sa filed Critical Ucb Sa

2001-01-15 Application granted granted Critical

2001-01-15 Publication of ATE198196T1 publication Critical patent/ATE198196T1/de

Links

208000010412 Glaucoma Diseases 0.000 title abstract 2
UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Substances C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000004410 intraocular pressure Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Ophthalmology & Optometry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

AT94870084T 1993-05-27 1994-05-19 2-hydroxy-3-(1-(1h-imidazol-4-yl)alkyl)-benzol carboximid-amide zur glaucoma-behandlung ATE198196T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939310965A GB9310965D0 (en)	1993-05-27	1993-05-27	2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides

Publications (1)

Publication Number	Publication Date
ATE198196T1 true ATE198196T1 (de)	2001-01-15

Family

ID=10736226

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94870084T ATE198196T1 (de)	1993-05-27	1994-05-19	2-hydroxy-3-(1-(1h-imidazol-4-yl)alkyl)-benzol carboximid-amide zur glaucoma-behandlung

Country Status (21)

Country	Link
US (1)	US5385927A (de)
EP (1)	EP0626372B1 (de)
JP (1)	JPH0770082A (de)
AT (1)	ATE198196T1 (de)
AU (1)	AU673422B2 (de)
CA (1)	CA2124289A1 (de)
CZ (1)	CZ287136B6 (de)
DE (1)	DE69426433D1 (de)
FI (1)	FI942390L (de)
GB (1)	GB9310965D0 (de)
HU (1)	HUT67813A (de)
IL (1)	IL109750A (de)
MY (1)	MY111216A (de)
NO (1)	NO303824B1 (de)
NZ (1)	NZ260588A (de)
PL (1)	PL175970B1 (de)
RU (1)	RU2125557C1 (de)
SG (1)	SG42791A1 (de)
SK (1)	SK60394A3 (de)
TW (1)	TW263500B (de)
ZA (1)	ZA943651B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9521680D0 (en) *	1995-10-23	1996-01-03	Orion Yhtymo Oy	New use of imidazole derivatives
JP2000514788A (ja)	1996-06-25	2000-11-07	イーライ・リリー・アンド・カンパニー	抗凝固剤
US6200967B1 (en)	1996-06-25	2001-03-13	Eli Lilly And Company	Anticoagulant agents
EP1365811A2 (de) *	2000-07-14	2003-12-03	Allergan, Inc.	Zusammensetzungen enthaltend alpha-2-adrenergische agonisten
US7902247B2 (en) *	2008-01-09	2011-03-08	Allergan, Inc.	Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors
EP2196461A1 (de)	2008-12-15	2010-06-16	Bayer CropScience AG	4-Amino-1,2,3-benzoxathiazin-Derivate als Pestizide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8626287D0 (en) *	1986-11-04	1986-12-03	Ucb Sa	Substituted 1h-imidazoles
GB8810067D0 (en) *	1988-04-28	1988-06-02	Ucb Sa	Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
FI98815C (fi) *	1990-11-30	1997-08-25	Santen Oy	Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi

1993
- 1993-05-27 GB GB939310965A patent/GB9310965D0/en active Pending
1994
- 1994-05-18 MY MYPI94001268A patent/MY111216A/en unknown
- 1994-05-19 DE DE69426433T patent/DE69426433D1/de not_active Expired - Lifetime
- 1994-05-19 SG SG1995001717A patent/SG42791A1/en unknown
- 1994-05-19 EP EP94870084A patent/EP0626372B1/de not_active Expired - Lifetime
- 1994-05-19 AT AT94870084T patent/ATE198196T1/de not_active IP Right Cessation
- 1994-05-20 CZ CZ19941247A patent/CZ287136B6/cs not_active IP Right Cessation
- 1994-05-23 PL PL94303566A patent/PL175970B1/pl unknown
- 1994-05-23 TW TW083104641A patent/TW263500B/zh active
- 1994-05-23 SK SK603-94A patent/SK60394A3/sk unknown
- 1994-05-24 IL IL109750A patent/IL109750A/en not_active IP Right Cessation
- 1994-05-24 US US08/248,205 patent/US5385927A/en not_active Expired - Fee Related
- 1994-05-24 FI FI942390A patent/FI942390L/fi unknown
- 1994-05-24 NZ NZ260588A patent/NZ260588A/en unknown
- 1994-05-25 CA CA002124289A patent/CA2124289A1/en not_active Abandoned
- 1994-05-25 RU RU94018525A patent/RU2125557C1/ru active
- 1994-05-25 ZA ZA943651A patent/ZA943651B/xx unknown
- 1994-05-25 AU AU63303/94A patent/AU673422B2/en not_active Ceased
- 1994-05-25 NO NO941932A patent/NO303824B1/no not_active IP Right Cessation
- 1994-05-25 HU HU9401574A patent/HUT67813A/hu unknown
- 1994-05-26 JP JP6112960A patent/JPH0770082A/ja active Pending

Also Published As

Publication number	Publication date
JPH0770082A (ja)	1995-03-14
SK60394A3 (en)	1995-07-11
FI942390A7 (fi)	1994-11-28
IL109750A (en)	1998-06-15
CA2124289A1 (en)	1994-11-28
EP0626372B1 (de)	2000-12-20
IL109750A0 (en)	1994-08-26
HUT67813A (en)	1995-05-29
AU6330394A (en)	1994-12-01
CZ287136B6 (en)	2000-09-13
NO303824B1 (no)	1998-09-07
CZ124794A3 (en)	1994-12-15
US5385927A (en)	1995-01-31
TW263500B (de)	1995-11-21
NO941932D0 (no)	1994-05-25
SG42791A1 (en)	1997-10-17
AU673422B2 (en)	1996-11-07
FI942390A0 (fi)	1994-05-24
RU2125557C1 (ru)	1999-01-27
PL175970B1 (pl)	1999-03-31
ZA943651B (en)	1995-01-26
DE69426433D1 (de)	2001-01-25
GB9310965D0 (en)	1993-07-14
NO941932L (no)	1994-11-28
HU9401574D0 (en)	1994-08-29
MY111216A (en)	1999-09-30
NZ260588A (en)	1995-09-26
EP0626372A1 (de)	1994-11-30
FI942390L (fi)	1994-11-28

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Legal Events

Date	Code	Title	Description
2001-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties