ATE198982T1 - Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen - Google Patents

Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Info

Publication number
ATE198982T1
ATE198982T1 AT95934711T AT95934711T ATE198982T1 AT E198982 T1 ATE198982 T1 AT E198982T1 AT 95934711 T AT95934711 T AT 95934711T AT 95934711 T AT95934711 T AT 95934711T AT E198982 T1 ATE198982 T1 AT E198982T1
Authority
AT
Austria
Prior art keywords
pct
active substance
dosage forms
pharmaceutically active
pharmaceutical dosage
Prior art date
Application number
AT95934711T
Other languages
English (en)
Inventor
Richard John Yarwood
Patrick Kearney
Andrew Roy Thompson
Original Assignee
Scherer Technologies Inc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P
Application granted granted Critical
Publication of ATE198982T1 publication Critical patent/ATE198982T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95934711T 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen ATE198982T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9421836A GB9421836D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
PCT/GB1995/002485 WO1996013251A1 (en) 1994-10-28 1995-10-20 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances

Publications (1)

Publication Number Publication Date
ATE198982T1 true ATE198982T1 (de) 2001-02-15

Family

ID=10763606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95934711T ATE198982T1 (de) 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Country Status (16)

Country Link
US (1) US5827541A (de)
EP (1) EP0737064B1 (de)
JP (1) JPH09511255A (de)
KR (1) KR100352881B1 (de)
CN (1) CN1236762C (de)
AT (1) ATE198982T1 (de)
AU (1) AU3702795A (de)
DE (1) DE69520036T2 (de)
DK (1) DK0737064T3 (de)
ES (1) ES2154737T3 (de)
GB (1) GB9421836D0 (de)
GR (1) GR3035427T3 (de)
MX (1) MX9602515A (de)
PL (1) PL187254B1 (de)
PT (1) PT737064E (de)
WO (1) WO1996013251A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration
US6277458B1 (en) * 1999-03-15 2001-08-21 The Procter & Gamble Company Release strip with partible break to facilitate
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
US6852337B2 (en) 1998-04-09 2005-02-08 Roche Diagnostics Gmbh Carvedilol-galenics
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
IL143197A0 (en) 1998-11-20 2002-04-21 Rtp Pharma Inc Dispersible phospholipid stabilized microparticles
US20010053791A1 (en) * 2000-03-16 2001-12-20 Babcock Walter C. Glycogen phosphorylase inhibitor
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
KR20030024849A (ko) * 2000-08-10 2003-03-26 델시스 파머수티컬 코포레이션 소수성 약물의 개선된 고형 약제학적 투여 제제
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
HU230253B1 (hu) 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DK1355644T3 (da) 2001-01-26 2006-10-23 Schering Corp Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
CA2440935A1 (en) 2001-03-13 2002-09-19 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
DE60220519T2 (de) * 2001-04-20 2007-09-27 The University Of British Columbia, Vancouver Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe
EP1423116A1 (de) * 2001-08-14 2004-06-02 Biotie Therapies Corp. Verfahren zur behandlung von alkoholismus oder alkoholmissbrauch
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
ES2292848T3 (es) * 2001-10-12 2008-03-16 Elan Pharma International Limited Composiciones que tienen una combinacion de caracteristicas de liberacion inmediata y liberacion controlada.
EP1941878A1 (de) 2002-01-10 2008-07-09 Biovail Laboratories International Srl Sedative Formulierungen ohne Benzodiazepin
WO2003063831A2 (en) * 2002-02-01 2003-08-07 Pfizer Products Inc. Immediate release dosage forms containing solid drug dispersions
WO2003080023A2 (en) * 2002-03-20 2003-10-02 Elan Pharma International Limited Fast dissolving dosage forms having reduced friability
AU2003256284A1 (en) * 2002-06-20 2004-01-06 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
CA2504610C (en) * 2002-11-12 2012-02-21 Elan Pharma International Ltd. Fast-disintegrating solid dosage forms being not friable and comprising pullulan
JP2006519869A (ja) * 2003-03-07 2006-08-31 シェーリング コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US20040224024A1 (en) * 2003-04-23 2004-11-11 Massachusetts Institute Of Technology Controlled drug release formulations containing polyion complexes
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
EP2322195A2 (de) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmazeutische Zusammensetzungen mit niedrigen Dosen von Desmopressin
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
EP1586313A1 (de) * 2004-04-07 2005-10-19 The Jordanian Pharmaceutical Manufacturing Co. Ltd. Metoclopramid enthaltende pharmazeutische Zubereitungen und Herstellungsmethode
DK1910384T3 (da) 2005-08-04 2012-12-17 Sirtris Pharmaceuticals Inc Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser
BRPI0620578A2 (pt) * 2005-12-27 2011-12-06 Jubilant Organosys Ltd composição farmacêutica que dissolve na boca e processo para o preparo da mesma
US20070243248A1 (en) * 2006-04-14 2007-10-18 Cherukuri S Rao Rapidly disintegrating solid oral dosage form of liquid dispersions
US20070259040A1 (en) * 2006-05-01 2007-11-08 Cherukuri S R Novel triptan formulations and methods for making them
TW200816985A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
US20070293582A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US20080039433A1 (en) * 2006-06-15 2008-02-14 Smith Alexander D Stabilized Tetracycline Compositions
FR2909877B1 (fr) * 2006-12-13 2009-07-10 Galenix Dev Soc Par Actions Si Composition pharmaceutique contenat de la 5-chloro-1-[1-[3- (2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl] piperidin-4-yl]-1,3-dihydro-2h-benzimidazol-2-one et son procede de preparation
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US8545879B2 (en) 2009-08-31 2013-10-01 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam
EP2359812A1 (de) 2010-01-18 2011-08-24 Cephalon France Lyophilisierte orale Zusammensetzungen
TR201002084A1 (tr) 2010-03-19 2011-10-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi
EP2377522B1 (de) 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulierungen von im Mund zerfallenden Mirtazapintabletten und Herstellungsverfahren dafür.
AU2011296027A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Fast-dissolve dosage forms of 5-HT2C agonists
EP2609911A1 (de) 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. Neuartiges Verfahren zur Herstellung von oral zerfallenden Flurbiprofen-Formulierungen
US8431155B1 (en) 2012-04-30 2013-04-30 Veroscience Llc Bromocriptine formulations
FR2997766B1 (fr) * 2012-11-08 2015-06-12 Alain Iltis Systeme et procede de detection de rayonnement gamma de type gamma camera
WO2016042372A1 (en) 2014-09-17 2016-03-24 Steer Engineering Private Limited Effervescent composition and method of making it
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN105560199B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮口崩片及其制备方法
CN105663055B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮干混悬剂及其制备方法
IL267689B2 (en) 2016-12-31 2025-05-01 Bioxcel Therapeutics Inc Use of sublingual dexmedetomidine for the treatment of agitation
CZ307916B6 (cs) 2017-05-08 2019-08-21 mcePharma s. r. o. Orodispergovatelná tableta s biodostupným kurkuminem a její použití
BR112020026672A2 (pt) 2018-06-27 2021-03-30 Bioxcel Therapeutics, Inc. Formulações de filme contendo dexmedetomidina e métodos para produzi-las
BR112022000992A2 (pt) 2019-07-19 2022-06-14 Arx Llc Regimes de tratamento de dexmedetomidina não sedantes
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
EP0081921A1 (de) * 1981-12-10 1983-06-22 Hawker Siddeley Revenue Controls Limited Kreditkartenverfahren
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
FR2661610B1 (fr) * 1990-05-02 1994-09-30 Rhone Poulenc Sante Nouvelle forme lyophilisee de la diosmine et sa preparation.
BR9205864A (pt) * 1991-04-08 1994-06-28 Sumitomo Pharma Formulações sólidas porosas contendo substâncias proteináceas fisiologicamente ativas.
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
EP0737064B1 (de) 2001-01-31
PT737064E (pt) 2001-05-31
EP0737064A1 (de) 1996-10-16
US5827541A (en) 1998-10-27
GR3035427T3 (en) 2001-05-31
JPH09511255A (ja) 1997-11-11
CN1236762C (zh) 2006-01-18
AU3702795A (en) 1996-05-23
PL187254B1 (pl) 2004-06-30
GB9421836D0 (en) 1994-12-14
ES2154737T3 (es) 2001-04-16
DK0737064T3 (da) 2001-02-26
DE69520036D1 (de) 2001-03-08
WO1996013251A1 (en) 1996-05-09
PL315181A1 (en) 1996-10-14
CN1140408A (zh) 1997-01-15
KR100352881B1 (ko) 2003-01-06
DE69520036T2 (de) 2001-06-21
MX9602515A (es) 1997-05-31

Similar Documents

Publication Publication Date Title
DE69520036D1 (de) Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen
DE69519664D1 (de) Verfahren zur herstellung fester pharmazeutischer dosierungsform
DE69521406D1 (de) Apparat und verfahren zur herstellung fester formen mit gesteuerter freisetzung des wirkstoffs
ATE204162T1 (de) Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix
ATE208612T1 (de) Biologisch erodierbare vorrichtung zur verabreichung von wirkstoffen
ATE204469T1 (de) Verfahren zur herstellung von morphologisch einheitlichen mikrokapseln sowie nach diesem verfahren hergestellte mikrokapseln
ATE353631T1 (de) System und verfahren zur herstellung arzneistoffbeladener mikropartikel
ATE361057T1 (de) Verfahren umfassend einen induzierten phasenübergang zur herstellung von hydrophobe wirkstoffe enthaltenden mikropartikeln
HUT63954A (en) Process for producing active ingredient containing microparticldes from hydrolytically degredable polymers
DE69921941D1 (de) Verfahren zur Herstellung von pharmazeutischen Wirkstoffpartikeln
DE69833375D1 (de) Implantate zur gesteuerten freisetzung von pharmazeutischen wirkstoffen und verfahren zur herstellung
ATE198152T1 (de) Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe
DE69104365D1 (de) Vaterit und verfahren zu dessen herstellung.
ATE221772T1 (de) Verfahren und apparat zur herstellung von schnelllöslichen dosierungseinheiten und daraus erhältliches produkt
DE69001573D1 (de) Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung.
ATE282406T1 (de) Arzneimittel und verfahren zur behandlung von intrazellulären infektionen
ATE204744T1 (de) Pharmazeutische zubereitung mit einem hydrophoben wirkstoff und einem brausesystem, sowie verfahren zur herstellung der zubereitung
ATE246515T1 (de) Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
DE59611383D1 (de) Darreichungsform zur applikation von pharmazeutischen wirkstoffen und hilfsstoffen und verfahren zur herstellung derselben
DE59604441D1 (de) Verfahren zur schonenden keimreduzierung von pharmazeutischen zubereitungen
NZ311681A (en) Process for producing active substances from unused or discarded devices for the transdermal administration of active substances and/or from their production waste
ATE288901T1 (de) Verfahren zur herstellung von 5-hydroxymethyl-2- oxazolidinon und neues zwischenprodukt
DE69813550D1 (de) Vorrichtung und verfahren zur herstellung von radioaktiven arzneimitteln zur verabreichung
ATE126285T1 (de) Verfahren und vorrichtung zur nassbehandlung von textilmaterialien sowie zur wiedereinstellung eines behandlungsbades.
ATE66468T1 (de) Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten.