ATE198982T1 - Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen - Google Patents

Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Info

Publication number
ATE198982T1
ATE198982T1 AT95934711T AT95934711T ATE198982T1 AT E198982 T1 ATE198982 T1 AT E198982T1 AT 95934711 T AT95934711 T AT 95934711T AT 95934711 T AT95934711 T AT 95934711T AT E198982 T1 ATE198982 T1 AT E198982T1
Authority
AT
Austria
Prior art keywords
pct
active substance
dosage forms
pharmaceutically active
pharmaceutical dosage
Prior art date
Application number
AT95934711T
Other languages
English (en)
Inventor
Richard John Yarwood
Patrick Kearney
Andrew Roy Thompson
Original Assignee
Scherer Technologies Inc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P
Application granted granted Critical
Publication of ATE198982T1 publication Critical patent/ATE198982T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95934711T 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen ATE198982T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9421836A GB9421836D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
PCT/GB1995/002485 WO1996013251A1 (en) 1994-10-28 1995-10-20 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances

Publications (1)

Publication Number Publication Date
ATE198982T1 true ATE198982T1 (de) 2001-02-15

Family

ID=10763606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95934711T ATE198982T1 (de) 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Country Status (16)

Country Link
US (1) US5827541A (de)
EP (1) EP0737064B1 (de)
JP (1) JPH09511255A (de)
KR (1) KR100352881B1 (de)
CN (1) CN1236762C (de)
AT (1) ATE198982T1 (de)
AU (1) AU3702795A (de)
DE (1) DE69520036T2 (de)
DK (1) DK0737064T3 (de)
ES (1) ES2154737T3 (de)
GB (1) GB9421836D0 (de)
GR (1) GR3035427T3 (de)
MX (1) MX9602515A (de)
PL (1) PL187254B1 (de)
PT (1) PT737064E (de)
WO (1) WO1996013251A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration
US6277458B1 (en) * 1999-03-15 2001-08-21 The Procter & Gamble Company Release strip with partible break to facilitate
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
US6852337B2 (en) 1998-04-09 2005-02-08 Roche Diagnostics Gmbh Carvedilol-galenics
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
US7939105B2 (en) * 1998-11-20 2011-05-10 Jagotec Ag Process for preparing a rapidly dispersing solid drug dosage form
WO2002085337A1 (en) * 2001-04-20 2002-10-31 The University Of British Columbia Micellar drug delivery systems for hydrophobic drugs
UY26615A1 (es) * 2000-03-16 2001-10-25 Pfizer Prod Inc Inhibidor de la glucogeno fosforilasa.
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
HUP0301668A2 (hu) * 2000-08-10 2003-09-29 Delsys Pharmaceutical Corporation Hidrofób hatóanyagok javított szilárd adagolási formái
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
PT1355644E (pt) 2001-01-26 2006-11-30 Schering Corp Utilização de compostos azetidinona substituídos para o tratamento de sitosterolemia
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
RS20100015A (sr) 2001-01-26 2010-12-31 Schering Corporation Kombinacija aktivatora receptora aktiviranog peroksizom- proliferatorom (ppar) fenofibrata sa inhibitorom apsorpcije sterola ezetimibom za vaskularne indikacije
US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
EP1418945A2 (de) * 2001-03-13 2004-05-19 Angiotech Pharmaceuticals, Inc. Mizellare arzneimittelabgabe vehikel und ihre anwendungen
PL368612A1 (en) * 2001-08-14 2005-04-04 Biotie Therapies Corporation Method of treating alcoholism or alcohol abuse
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
EP1429756B1 (de) 2001-09-21 2006-11-22 Schering Corporation Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
DE60222160T2 (de) * 2001-10-12 2008-06-12 Elan Pharma International Ltd., Athlone Zusammensetzungen mit einer kombination aus eigenschaften sofortiger freisetzung und kontrollierter freisetzung
EP1941878A1 (de) 2002-01-10 2008-07-09 Biovail Laboratories International Srl Sedative Formulierungen ohne Benzodiazepin
CN1688291A (zh) * 2002-02-01 2005-10-26 辉瑞产品公司 含有固体药物分散体的即刻释放剂型
EP1487419A2 (de) * 2002-03-20 2004-12-22 Elan Pharma International Limited Schnell auflösende dosierformen mit verringerter sprödigkeit
AU2003256284A1 (en) * 2002-06-20 2004-01-06 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
JP2006508188A (ja) 2002-11-06 2006-03-09 シェーリング　コーポレイション 脱髄の処置のためのコレステロール吸収インヒビター
JP4776233B2 (ja) * 2002-11-12 2011-09-21 エラン ファーマ インターナショナル，リミティド 摩損しにくくかつプルランを含む速崩壊性固形製剤
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
DE602004016123D1 (de) 2003-03-07 2008-10-09 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
CN1756755A (zh) * 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
CN1756756A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US20040224024A1 (en) * 2003-04-23 2004-11-11 Massachusetts Institute Of Technology Controlled drug release formulations containing polyion complexes
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
CA2866501A1 (en) 2003-11-10 2005-05-26 Allergan, Inc. Pharmaceutical compositions including low dosages of desmopressin
EP1586313A1 (de) * 2004-04-07 2005-10-19 The Jordanian Pharmaceutical Manufacturing Co. Ltd. Metoclopramid enthaltende pharmazeutische Zubereitungen und Herstellungsmethode
EP1909910A1 (de) 2005-08-04 2008-04-16 Sirtris Pharmaceuticals, Inc. Benzimidazol-derivative als sirtuin-modulatoren
EP1978939A2 (de) * 2005-12-27 2008-10-15 Jubilant Organosys Limited Sich im mund auflösende pharmazeutische zusammensetzung und verfahren zu ihrer herstellung unter verwendung einer grossen menge von siliziumdioxin
US20070243248A1 (en) * 2006-04-14 2007-10-18 Cherukuri S Rao Rapidly disintegrating solid oral dosage form of liquid dispersions
WO2007130373A2 (en) * 2006-05-01 2007-11-15 Capricorn Pharma, Inc. Novel triptan formulations and methods for making them
US20070293580A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US20080039433A1 (en) * 2006-06-15 2008-02-14 Smith Alexander D Stabilized Tetracycline Compositions
FR2909877B1 (fr) * 2006-12-13 2009-07-10 Galenix Dev Soc Par Actions Si Composition pharmaceutique contenat de la 5-chloro-1-[1-[3- (2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl] piperidin-4-yl]-1,3-dihydro-2h-benzimidazol-2-one et son procede de preparation
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US8545879B2 (en) 2009-08-31 2013-10-01 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam
EP2359812A1 (de) 2010-01-18 2011-08-24 Cephalon France Lyophilisierte orale Zusammensetzungen
TR201002084A1 (tr) 2010-03-19 2011-10-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi
EP2377522B1 (de) 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulierungen von im Mund zerfallenden Mirtazapintabletten und Herstellungsverfahren dafür.
EP2611781A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Schnelllösliche darreichungsformen von 5-ht2c-agonisten
EP2609911A1 (de) 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. Neuartiges Verfahren zur Herstellung von oral zerfallenden Flurbiprofen-Formulierungen
US8431155B1 (en) * 2012-04-30 2013-04-30 Veroscience Llc Bromocriptine formulations
FR2997766B1 (fr) * 2012-11-08 2015-06-12 Alain Iltis Systeme et procede de detection de rayonnement gamma de type gamma camera
CA3018828C (en) 2014-09-17 2021-05-11 Steerlife India Private Limited Effervescent composition and method of making it
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN105663055B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮干混悬剂及其制备方法
CN105560199B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮口崩片及其制备方法
SG10202107367SA (en) 2016-12-31 2021-08-30 Bioxcel Therapeutics Inc Use of sublingual dexmedetomidine for the treatment of agitation
CZ307916B6 (cs) 2017-05-08 2019-08-21 mcePharma s. r. o. Orodispergovatelná tableta s biodostupným kurkuminem a její použití
ES3004544T3 (en) 2018-06-27 2025-03-12 Bioxcel Therapeutics Inc Film formulations containing dexmedetomidine and methods of producing them
US20240024288A1 (en) 2019-07-19 2024-01-25 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
GB2111280B (en) * 1981-12-10 1985-05-09 Hawker Siddeley Revenue Contr Credit card freed dispensing system
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
FR2661610B1 (fr) * 1990-05-02 1994-09-30 Rhone Poulenc Sante Nouvelle forme lyophilisee de la diosmine et sa preparation.
EP0578823B1 (de) * 1991-04-08 2002-01-23 Sumitomo Pharmaceuticals Company, Limited Poröse feste zubereitung, die eine physiologische aktive proteinverbindung enthält
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
MX9602515A (es) 1997-05-31
EP0737064A1 (de) 1996-10-16
PT737064E (pt) 2001-05-31
AU3702795A (en) 1996-05-23
JPH09511255A (ja) 1997-11-11
DE69520036T2 (de) 2001-06-21
ES2154737T3 (es) 2001-04-16
KR100352881B1 (ko) 2003-01-06
EP0737064B1 (de) 2001-01-31
PL315181A1 (en) 1996-10-14
CN1236762C (zh) 2006-01-18
PL187254B1 (pl) 2004-06-30
DE69520036D1 (de) 2001-03-08
GB9421836D0 (en) 1994-12-14
WO1996013251A1 (en) 1996-05-09
DK0737064T3 (da) 2001-02-26
US5827541A (en) 1998-10-27
CN1140408A (zh) 1997-01-15
GR3035427T3 (en) 2001-05-31

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