ATE199640T1 - Verfahren zum kontrollieren der liposomengrösse - Google Patents

Verfahren zum kontrollieren der liposomengrösse

Info

Publication number
ATE199640T1
ATE199640T1 AT94921494T AT94921494T ATE199640T1 AT E199640 T1 ATE199640 T1 AT E199640T1 AT 94921494 T AT94921494 T AT 94921494T AT 94921494 T AT94921494 T AT 94921494T AT E199640 T1 ATE199640 T1 AT E199640T1
Authority
AT
Austria
Prior art keywords
liposome size
controlling
controlling liposome
particle size
mean particle
Prior art date
Application number
AT94921494T
Other languages
English (en)
Inventor
Laura M Edgerly-Pflug
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE199640T1 publication Critical patent/ATE199640T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT94921494T 1993-07-08 1994-07-08 Verfahren zum kontrollieren der liposomengrösse ATE199640T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8874293A 1993-07-08 1993-07-08
PCT/US1994/007683 WO1995001777A1 (en) 1993-07-08 1994-07-08 Method of controlling the size of liposomes

Publications (1)

Publication Number Publication Date
ATE199640T1 true ATE199640T1 (de) 2001-03-15

Family

ID=22213183

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94921494T ATE199640T1 (de) 1993-07-08 1994-07-08 Verfahren zum kontrollieren der liposomengrösse

Country Status (11)

Country Link
US (1) US6596305B1 (de)
EP (1) EP0707472B1 (de)
JP (1) JP3479535B2 (de)
AT (1) ATE199640T1 (de)
CA (1) CA2166465C (de)
DE (1) DE69426884T2 (de)
DK (1) DK0707472T3 (de)
ES (1) ES2154680T3 (de)
GR (1) GR3035825T3 (de)
PT (1) PT707472E (de)
WO (1) WO1995001777A1 (de)

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US6001333A (en) * 1997-09-12 1999-12-14 See; Jackie R. Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging
EP1150658B1 (de) * 1999-02-08 2004-08-04 Alza Corporation Verfahren zur kontrolle der liposomengrösse
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
PL371626A1 (en) * 2002-01-21 2005-06-27 Vasogen Ireland Limited Pharmaceutically acceptable phosphate-glycerol carrying bodies
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
EP1519714B1 (de) 2002-06-28 2010-10-20 Protiva Biotherapeutics Inc. Verfahren und vorrichtung zur herstellung von liposomen
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US9198645B2 (en) * 2003-11-26 2015-12-01 The United States of America, as represented by the Secretary of Commerce of The National Institute of Standards and Technology Controlled vesicle self-assembly in continuous two phase flow microfluidic channels
US20050129750A1 (en) * 2003-12-15 2005-06-16 Yu-Fang Hu Process for producing liposome suspension and product containing liposome suspension produced thereby
US8784881B2 (en) * 2004-03-05 2014-07-22 Board Of Regents, The University Of Texas System Liposomal curcumin for treatment of diseases
US8715591B2 (en) * 2004-07-21 2014-05-06 The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology Microfluidic apparatus to control liposome formation
CN103989633A (zh) * 2005-07-27 2014-08-20 普洛体维生物治疗公司 制造脂质体的系统和方法
JP5324223B2 (ja) 2005-12-08 2013-10-23 トランセイブ， インク． 肺感染症を治療する抗感染薬の脂質ベースの組成物及びその使用法
AU2006321796A1 (en) * 2005-12-08 2007-06-14 Wyeth Liposomal compositions
WO2007117550A2 (en) * 2006-04-06 2007-10-18 Transave, Inc. Methods for coacervation induced liposomal encapsulation and formulations thereof
US20080268031A1 (en) * 2007-03-15 2008-10-30 Benjamin Johnson Therapeutic Treatment of Dermatologic Skin Disorders
CA2681302C (en) * 2007-03-19 2013-07-23 Dhiraj Khattar Proliposomal and liposomal compositions of poorly water-soluble compounds
US20100196455A1 (en) * 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
WO2009091531A2 (en) * 2008-01-16 2009-07-23 The General Hospital Corporation Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery
US20090246234A1 (en) * 2008-04-01 2009-10-01 Benjamin Johnson Therapeutic Treatment Using Niacin for Skin Disorders
US20100081956A1 (en) * 2008-09-30 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method, composition, and system to control pH in pulmonary tissue of a subject
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
TWI410256B (zh) * 2010-01-07 2013-10-01 Nat Univ Tsing Hua 雙重乳化法製備微脂體之新型裝置
CA2834968C (en) * 2011-01-05 2018-01-09 Livon Laboratories Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
US8642655B2 (en) 2011-03-09 2014-02-04 Benjamin Johnson Systems and methods for preventing cancer and treating skin lesions
GB201116248D0 (en) * 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
CN104427976B (zh) * 2012-05-10 2018-04-24 佩因拉佛姆有限公司 疏水的活性成分的储库制剂及其制备方法
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
MX2015006681A (es) 2012-11-29 2016-04-06 Insmed Inc Formulaciones de vancomicina estabilizadas.
SMT202000516T1 (it) 2014-05-15 2020-11-10 Insmed Inc Metodi per trattamento di infezioni micobatteriche polmonati non tubercolari
CN106568831B (zh) * 2016-11-18 2019-07-23 武汉理工大学 一种用于检测磷酸肌醇的多孔膜材料及其制备与检测方法
US11260028B2 (en) * 2017-06-26 2022-03-01 Fordoz Pharma Corp. Nanosome formulations of aprepitant and methods and applications thereof
WO2019028186A1 (en) * 2017-08-01 2019-02-07 Ankasa Regenerative Therapeutics, Inc. WNT COMPOSITIONS AND METHODS OF TREATMENT FROM SERUM-FREE CULTURE CONDITIONS
CN111565833B (zh) * 2017-11-01 2023-04-07 国立大学法人大阪大学 用于制造具有期望的粒径的脂质颗粒的方法及装置的开发
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
WO2019213398A1 (en) 2018-05-02 2019-11-07 Insmed Incorporated Methods for the manufacture of liposomal drug formulations
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method

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US4184849A (en) * 1977-12-05 1980-01-22 Technicon Instruments Corporation Mixed agglutination
US4529561A (en) 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
US4522803A (en) 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
US4588578A (en) 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
CA1237670A (en) 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
EP0158441B2 (de) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposombildende Zusammensetzung
US4721612A (en) 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US4619895A (en) * 1984-05-10 1986-10-28 The Regents Of The University Of California Lipoprotein marker for hypertriglyceridemia
US5008050A (en) 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US5077056A (en) 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
GB8426264D0 (en) 1984-10-17 1984-11-21 Alcan Int Ltd Porous films
US4861580A (en) 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
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US5154930A (en) 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
WO1988009170A1 (en) 1987-05-22 1988-12-01 The Liposome Company, Inc. Prostaglandin-lipid formulations
ATE113468T1 (de) 1987-07-29 1994-11-15 Liposome Co Inc Verfahren zur trennung von teilchen nach grösse.
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
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WO1990011780A1 (en) 1989-03-31 1990-10-18 The Regents Of The University Of California Preparation of liposome and lipid complex compositions

Also Published As

Publication number Publication date
GR3035825T3 (en) 2001-07-31
CA2166465A1 (en) 1995-01-19
DE69426884D1 (de) 2001-04-19
ES2154680T3 (es) 2001-04-16
EP0707472A1 (de) 1996-04-24
PT707472E (pt) 2001-07-31
DE69426884T2 (de) 2001-06-21
CA2166465C (en) 2003-10-14
EP0707472B1 (de) 2001-03-14
JPH08512240A (ja) 1996-12-24
US6596305B1 (en) 2003-07-22
WO1995001777A1 (en) 1995-01-19
DK0707472T3 (da) 2001-04-17
JP3479535B2 (ja) 2003-12-15

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Legal Events

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