ATE199640T1 - Verfahren zum kontrollieren der liposomengrösse - Google Patents

Verfahren zum kontrollieren der liposomengrösse

Info

Publication number
ATE199640T1
ATE199640T1 AT94921494T AT94921494T ATE199640T1 AT E199640 T1 ATE199640 T1 AT E199640T1 AT 94921494 T AT94921494 T AT 94921494T AT 94921494 T AT94921494 T AT 94921494T AT E199640 T1 ATE199640 T1 AT E199640T1
Authority
AT
Austria
Prior art keywords
liposome size
controlling
controlling liposome
particle size
mean particle
Prior art date
Application number
AT94921494T
Other languages
English (en)
Inventor
Laura M Edgerly-Pflug
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE199640T1 publication Critical patent/ATE199640T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT94921494T 1993-07-08 1994-07-08 Verfahren zum kontrollieren der liposomengrösse ATE199640T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8874293A 1993-07-08 1993-07-08
PCT/US1994/007683 WO1995001777A1 (en) 1993-07-08 1994-07-08 Method of controlling the size of liposomes

Publications (1)

Publication Number Publication Date
ATE199640T1 true ATE199640T1 (de) 2001-03-15

Family

ID=22213183

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94921494T ATE199640T1 (de) 1993-07-08 1994-07-08 Verfahren zum kontrollieren der liposomengrösse

Country Status (11)

Country Link
US (1) US6596305B1 (de)
EP (1) EP0707472B1 (de)
JP (1) JP3479535B2 (de)
AT (1) ATE199640T1 (de)
CA (1) CA2166465C (de)
DE (1) DE69426884T2 (de)
DK (1) DK0707472T3 (de)
ES (1) ES2154680T3 (de)
GR (1) GR3035825T3 (de)
PT (1) PT707472E (de)
WO (1) WO1995001777A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001333A (en) * 1997-09-12 1999-12-14 See; Jackie R. Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging
JP2002536316A (ja) * 1999-02-08 2002-10-29 アルザ・コーポレーション リポソームサイズを調節する方法
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
AU2003201569B2 (en) * 2002-01-21 2008-09-11 Vasogen Ireland Limited Pharmaceutically acceptable phosphate-glycerol carrying bodies
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
EP1519714B1 (de) 2002-06-28 2010-10-20 Protiva Biotherapeutics Inc. Verfahren und vorrichtung zur herstellung von liposomen
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US9198645B2 (en) * 2003-11-26 2015-12-01 The United States of America, as represented by the Secretary of Commerce of The National Institute of Standards and Technology Controlled vesicle self-assembly in continuous two phase flow microfluidic channels
US20050129750A1 (en) * 2003-12-15 2005-06-16 Yu-Fang Hu Process for producing liposome suspension and product containing liposome suspension produced thereby
US8784881B2 (en) * 2004-03-05 2014-07-22 Board Of Regents, The University Of Texas System Liposomal curcumin for treatment of diseases
US8715591B2 (en) * 2004-07-21 2014-05-06 The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology Microfluidic apparatus to control liposome formation
CN101267805A (zh) * 2005-07-27 2008-09-17 普洛体维生物治疗公司 制造脂质体的系统和方法
EP3067047B1 (de) 2005-12-08 2022-04-20 Insmed Incorporated Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
CA2631243A1 (en) * 2005-12-08 2007-06-14 Wyeth Liposomal compositions
EP2012750B1 (de) * 2006-04-06 2018-02-21 Insmed Incorporated Verfahren für koazervationsinduzierte liposomale verkapselung und formulierungen daraus
US20080268031A1 (en) * 2007-03-15 2008-10-30 Benjamin Johnson Therapeutic Treatment of Dermatologic Skin Disorders
EP2146692A1 (de) * 2007-03-19 2010-01-27 Fresenius Kabi Oncology Limited Proliposomale und liposomale zusammensetzungen
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
WO2009091531A2 (en) * 2008-01-16 2009-07-23 The General Hospital Corporation Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery
US20090246234A1 (en) * 2008-04-01 2009-10-01 Benjamin Johnson Therapeutic Treatment Using Niacin for Skin Disorders
US20100081956A1 (en) * 2008-09-30 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method, composition, and system to control pH in pulmonary tissue of a subject
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
TWI410256B (zh) * 2010-01-07 2013-10-01 Nat Univ Tsing Hua 雙重乳化法製備微脂體之新型裝置
CA2834968C (en) * 2011-01-05 2018-01-09 Livon Laboratories Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
US8642655B2 (en) 2011-03-09 2014-02-04 Benjamin Johnson Systems and methods for preventing cancer and treating skin lesions
GB201116248D0 (en) * 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
EP2846773A4 (de) * 2012-05-10 2015-12-30 Painreform Ltd Depotformulierungen eines lokalanästhetikums und verfahren zur herstellung davon
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
LT3466432T (lt) 2014-05-15 2020-12-28 Insmed Incorporated Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
CN106568831B (zh) * 2016-11-18 2019-07-23 武汉理工大学 一种用于检测磷酸肌醇的多孔膜材料及其制备与检测方法
WO2019005830A1 (en) * 2017-06-26 2019-01-03 Fordoz Pharma Corp. NANOSOME FORMULATIONS OF APREPITANT AND METHODS AND APPLICATIONS THEREOF
CN111182880B (zh) * 2017-08-01 2024-01-09 安卡萨再生疗法公司 Wnt组合物和从无血清培养条件进行的工艺方法
US11638695B2 (en) * 2017-11-01 2023-05-02 Osaka University Development of method and apparatus for producing lipid particles having desired particle diameter
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
EP3773505B1 (de) 2018-03-30 2026-04-29 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
JP7449275B2 (ja) 2018-05-02 2024-03-13 インスメッド インコーポレイテッド リポソーム薬物製剤の製造方法
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039285A (en) * 1975-10-10 1977-08-02 Ortho Diagnostics, Inc. Single sample method for determination of lipoprotein concentrations in blood
US4184849A (en) * 1977-12-05 1980-01-22 Technicon Instruments Corporation Mixed agglutination
US4529561A (en) 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
US4522803A (en) 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
US4588578A (en) 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
CA1237670A (en) 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
JPH0753661B2 (ja) * 1984-03-08 1995-06-07 フアレス フアーマスーチカル リサーチ エヌブイ プロ―リポソーム組成物及びリポソームの水性分散物を作る方法
US4721612A (en) 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US4619895A (en) * 1984-05-10 1986-10-28 The Regents Of The University Of California Lipoprotein marker for hypertriglyceridemia
US5008050A (en) 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US5077056A (en) 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
GB8426264D0 (en) 1984-10-17 1984-11-21 Alcan Int Ltd Porous films
US4861580A (en) 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US5154930A (en) 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
US5082664A (en) 1987-05-22 1992-01-21 The Liposome Company, Inc. Prostaglandin-lipid formulations
ATE113468T1 (de) 1987-07-29 1994-11-15 Liposome Co Inc Verfahren zur trennung von teilchen nach grösse.
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
US4994213A (en) * 1988-05-17 1991-02-19 Liposome Technology, Inc. Method of preparing lipid structures
WO1989011335A1 (en) 1988-05-17 1989-11-30 Liposome Technology, Inc. Preparation of uniform-size liposomes and other lipid structures
US4927637A (en) 1989-01-17 1990-05-22 Liposome Technology, Inc. Liposome extrusion method
EP0467954B1 (de) 1989-03-31 1996-05-01 The Regents Of The University Of California Zubereitung von liposomen- und lipid-komplexzusammensetzungen

Also Published As

Publication number Publication date
US6596305B1 (en) 2003-07-22
DK0707472T3 (da) 2001-04-17
ES2154680T3 (es) 2001-04-16
JPH08512240A (ja) 1996-12-24
EP0707472A1 (de) 1996-04-24
DE69426884D1 (de) 2001-04-19
PT707472E (pt) 2001-07-31
CA2166465C (en) 2003-10-14
JP3479535B2 (ja) 2003-12-15
GR3035825T3 (en) 2001-07-31
WO1995001777A1 (en) 1995-01-19
EP0707472B1 (de) 2001-03-14
CA2166465A1 (en) 1995-01-19
DE69426884T2 (de) 2001-06-21

Similar Documents

Publication Publication Date Title
ATE199640T1 (de) Verfahren zum kontrollieren der liposomengrösse
DE69407663D1 (de) Verfahren zum Herstellen von Doppelplüschgeweben
DE69622505D1 (de) Verfahren zum herstellen von luftreifen
DE69308399D1 (de) Verfahren zum Herstellen von Prägewalzen
DE69410851D1 (de) Verfahren zum Aufbauen von Rohreifen
DE69206862D1 (de) Verfahren zum Herstellen von organischen Carbonaten
FI945958A7 (fi) Menetelmä polyolefiinien valmistamiseksi
DE59408739D1 (de) Verfahren zum Herstellen von lackierten Teilen
DE69411448D1 (de) Verfahren zum Herstellen von Silizium enthaltenden Kathoden-Targets
DE69517557D1 (de) Verfahren zum Herstellen von Elektrostahl
DE59406736D1 (de) Verfahren zum herstellen von kunststofformteilen mit kaschierung aus dekormaterial
ATE201025T1 (de) Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren
DE3686738D1 (de) Verfahren zum herstellen von hochreinem niob.
DE69610187D1 (de) Verfahren zum Herstellen von aromatischen Carbonaten
DE59301293D1 (de) Verfahren zur Herstellung von Vinylglykolen, durch Isomerisierung
DE69411254D1 (de) Verfahren zum kontinuierlichen Herstellen von Dimethylcarbonat
ATE175957T1 (de) Verfahren zur herstellung von alkoxyiminoacetamid-verbindungen
DE69830624D1 (de) Verfahren zum Herstellen von organischen Fluorverbindungen
DE69406395D1 (de) Verfahren zum kontinuierlichen Herstellen von Dimethylcarbonat
DE59600108D1 (de) Verfahren zum Herstellen von unterschiedlich dimensionierten Sattelspulen
DE59307795D1 (de) Verfahren zur herstellung von rückstandsfreiem 2,4/2,6-diaminotoluolgemisch
HU9202230D0 (en) Method for producing beta-lactames
DE69414335D1 (de) Vorrichtung zum Herstellen von geschliffenen Hohlnadeln
DE69405670D1 (de) Verfahren zum Herstellen von Diestern ungesättigter Glykole
DE69627503D1 (de) Verfahren zum herstellen von holzwerkstoffplatten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee