ATE200484T1 - Verfahren zur herstellung von optisch aktiven 1,4-dihydropyridinen - Google Patents
Verfahren zur herstellung von optisch aktiven 1,4-dihydropyridinenInfo
- Publication number
- ATE200484T1 ATE200484T1 AT93919593T AT93919593T ATE200484T1 AT E200484 T1 ATE200484 T1 AT E200484T1 AT 93919593 T AT93919593 T AT 93919593T AT 93919593 T AT93919593 T AT 93919593T AT E200484 T1 ATE200484 T1 AT E200484T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydropyridines
- nitrophenyl
- dihydro
- dimethyl
- optically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23187792 | 1992-08-31 | ||
| PCT/JP1993/001222 WO1994005637A1 (fr) | 1992-08-31 | 1993-08-31 | Compose a base de 1,4-dihydropyridine presentant une activite optique et procede de production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE200484T1 true ATE200484T1 (de) | 2001-04-15 |
Family
ID=16930427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93919593T ATE200484T1 (de) | 1992-08-31 | 1993-08-31 | Verfahren zur herstellung von optisch aktiven 1,4-dihydropyridinen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5635395A (de) |
| EP (1) | EP0657429B1 (de) |
| KR (1) | KR100244728B1 (de) |
| AT (1) | ATE200484T1 (de) |
| AU (1) | AU4981893A (de) |
| CA (1) | CA2143106A1 (de) |
| DE (1) | DE69330130T2 (de) |
| WO (1) | WO1994005637A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1089337C (zh) * | 1994-08-29 | 2002-08-21 | 美而香株式会社 | 1,4-二氢吡啶衍生物 |
| US6143541A (en) * | 1995-07-31 | 2000-11-07 | Mercian Corporation | Gene encoding a protein having symmetric hydrolase activity for 4-substituted 1,4-dihydropyridine derivatives and its expression product |
| EP0985667A4 (de) * | 1997-04-25 | 2000-03-22 | Ajinomoto Kk | Neue dihydropyridin-derivate |
| US6145143A (en) * | 1999-06-03 | 2000-11-14 | Kinetic Concepts, Inc. | Patient support systems with layered fluid support mediums |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4656181A (en) * | 1982-11-24 | 1987-04-07 | Cermol S.A. | Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same |
| JP2691986B2 (ja) * | 1987-08-28 | 1997-12-17 | チッソ株式会社 | ピリジン骨格を有する光学活性化合物の製造法 |
| JPH0641075A (ja) * | 1990-09-01 | 1994-02-15 | Kazuo Achinami | 新規な1,4−ジヒドロピリジン化合物及びその製造方法 |
| US5234821A (en) * | 1990-09-01 | 1993-08-10 | Kazuo Achiwa | Process for preparing 1,4 dihydropyridine compounds |
| US5100892A (en) * | 1990-11-13 | 1992-03-31 | Glaxo Inc. | Dihydropyridine vasodilator agents |
| JPH0584089A (ja) * | 1991-03-01 | 1993-04-06 | Taisho Pharmaceut Co Ltd | 光学活性1,4−ジヒドロピリジン化合物の製造法 |
| JPH04299994A (ja) * | 1991-03-26 | 1992-10-23 | Taisho Pharmaceut Co Ltd | 光学活性1,4−ジヒドロピリジン化合物の製造法 |
| JP3286645B2 (ja) * | 1993-03-26 | 2002-05-27 | メルシャン株式会社 | 光学活性1,4−ジヒドロピリジン誘導体およびその製造方法 |
-
1993
- 1993-08-31 CA CA002143106A patent/CA2143106A1/en not_active Abandoned
- 1993-08-31 DE DE69330130T patent/DE69330130T2/de not_active Expired - Fee Related
- 1993-08-31 WO PCT/JP1993/001222 patent/WO1994005637A1/ja not_active Ceased
- 1993-08-31 KR KR1019950700567A patent/KR100244728B1/ko not_active Expired - Fee Related
- 1993-08-31 EP EP93919593A patent/EP0657429B1/de not_active Expired - Lifetime
- 1993-08-31 AT AT93919593T patent/ATE200484T1/de active
- 1993-08-31 AU AU49818/93A patent/AU4981893A/en not_active Abandoned
- 1993-08-31 US US08/387,750 patent/US5635395A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2143106A1 (en) | 1994-03-17 |
| WO1994005637A1 (fr) | 1994-03-17 |
| KR950702963A (ko) | 1995-08-23 |
| EP0657429A4 (de) | 1996-03-27 |
| EP0657429B1 (de) | 2001-04-11 |
| DE69330130T2 (de) | 2001-08-02 |
| US5635395A (en) | 1997-06-03 |
| AU4981893A (en) | 1994-03-29 |
| EP0657429A1 (de) | 1995-06-14 |
| KR100244728B1 (ko) | 2000-03-02 |
| DE69330130D1 (de) | 2001-05-17 |
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