ATE201404T1 - Epoxysuccinamid-derivate oder deren salze und medikamente die diese enthalten - Google Patents

Epoxysuccinamid-derivate oder deren salze und medikamente die diese enthalten

Info

Publication number
ATE201404T1
ATE201404T1 AT96941212T AT96941212T ATE201404T1 AT E201404 T1 ATE201404 T1 AT E201404T1 AT 96941212 T AT96941212 T AT 96941212T AT 96941212 T AT96941212 T AT 96941212T AT E201404 T1 ATE201404 T1 AT E201404T1
Authority
AT
Austria
Prior art keywords
aralkyl group
group
salts
substituted
aromatic hydrocarbon
Prior art date
Application number
AT96941212T
Other languages
English (en)
Inventor
Tomohiro Yamashita
Yoshimitsu Suda
Yukio Tada
Nobuhiko Katsunuma
Tetsuji Asao
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE201404T1 publication Critical patent/ATE201404T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96941212T 1995-12-12 1996-12-10 Epoxysuccinamid-derivate oder deren salze und medikamente die diese enthalten ATE201404T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32297195 1995-12-12
PCT/JP1996/003603 WO1997021694A1 (en) 1995-12-12 1996-12-10 Epoxysuccinamide derivatives or salts thereof, and drugs containing the same

Publications (1)

Publication Number Publication Date
ATE201404T1 true ATE201404T1 (de) 2001-06-15

Family

ID=18149701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96941212T ATE201404T1 (de) 1995-12-12 1996-12-10 Epoxysuccinamid-derivate oder deren salze und medikamente die diese enthalten

Country Status (9)

Country Link
US (1) US5883121A (de)
EP (1) EP0808839B1 (de)
JP (1) JP3338452B2 (de)
KR (1) KR100226461B1 (de)
AT (1) ATE201404T1 (de)
AU (1) AU697565B2 (de)
CA (1) CA2211128C (de)
DE (1) DE69612962T2 (de)
WO (1) WO1997021694A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69814800T2 (de) * 1997-04-18 2003-12-18 Taiho Pharmaceutical Co. Ltd., Tokio/Tokyo Epoxysuccinamid-derivate oder ihre salze
EP1384713B1 (de) * 1998-12-23 2008-10-15 SmithKline Beecham Corporation 4-Amino-azepan-3-on-Derivate als Protease-Inhibitors
CN1253441C (zh) * 1998-12-23 2006-04-26 史密丝克莱恩比彻姆公司 蛋白酶抑制剂
US6605589B1 (en) 2000-03-31 2003-08-12 Parker Hughes Institute Cathepsin inhibitors in cancer treatment
US20040009891A1 (en) * 2001-02-14 2004-01-15 Newmillennium Pharmaceutical, Inc. Method and composition for treating obesity by targeting cathepsin
US6620844B2 (en) * 2001-02-14 2003-09-16 Newmillennium Pharmaceutical, Inc. Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
WO2004084830A2 (en) * 2003-03-21 2004-10-07 Buck Institute Method for treating alzheimer’s dementia
US9144594B2 (en) * 2005-11-08 2015-09-29 University Of Miami Cathepsin L mediated diseases and associated methods and products
WO2007056435A2 (en) * 2005-11-08 2007-05-18 The General Hospital Corporation Dynamin mediated diseases and associated methods and products
KR20090029725A (ko) 2006-06-13 2009-03-23 더 보드 오브 트러스티즈 오프 더 리랜드 스탠포드 쥬니어 유니버시티 시스테인 프로테아제의 에폭시드 저해물질
US20110092484A1 (en) 2007-06-08 2011-04-21 Nippon Chemiphar Co., Ltd. Therapeutic or prophylactic agent for cerebral aneurysm
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
JP6533466B2 (ja) * 2012-12-18 2019-06-19 ザ セクレタリー オブ ステート フォー ヘルスＴｈｅ Ｓｅｃｒｅｔａｒｙ Ｏｆ Ｓｔａｔｅ Ｆｏｒ Ｈｅａｌｔｈ 抗菌性化合物、その合成およびその適用
CN107151236B (zh) 2016-03-03 2021-04-30 中国人民解放军军事医学科学院毒物药物研究所 一种2,3-环氧丁二酰衍生物及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556853A (en) * 1993-10-29 1996-09-17 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives
US5438267A (en) * 1994-01-26 1995-08-01 Baker Hughes Incorporated Single-switching method of eliminating the effect of electromagnetic coupling between a pair of receivers

Also Published As

Publication number Publication date
EP0808839A4 (de) 1998-12-02
US5883121A (en) 1999-03-16
DE69612962T2 (de) 2001-11-15
JP3338452B2 (ja) 2002-10-28
KR100226461B1 (ko) 1999-10-15
EP0808839B1 (de) 2001-05-23
CA2211128C (en) 2001-02-06
CA2211128A1 (en) 1997-06-19
EP0808839A1 (de) 1997-11-26
AU1041497A (en) 1997-07-03
KR19980701741A (ko) 1998-06-25
DE69612962D1 (de) 2001-06-28
AU697565B2 (en) 1998-10-08
WO1997021694A1 (en) 1997-06-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties