ATE202476T1 - Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam - Google Patents
Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicamInfo
- Publication number
- ATE202476T1 ATE202476T1 AT94903120T AT94903120T ATE202476T1 AT E202476 T1 ATE202476 T1 AT E202476T1 AT 94903120 T AT94903120 T AT 94903120T AT 94903120 T AT94903120 T AT 94903120T AT E202476 T1 ATE202476 T1 AT E202476T1
- Authority
- AT
- Austria
- Prior art keywords
- absorption
- piroxicam
- pharmaceutical compositions
- percutane
- improved
- Prior art date
Links
- 238000010521 absorption reaction Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002702 piroxicam Drugs 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR920027130 | 1992-12-31 | ||
| PCT/KR1993/000127 WO1994015609A1 (en) | 1992-12-31 | 1993-12-31 | Enhanced pharmaceutical compositions for skin penetration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE202476T1 true ATE202476T1 (de) | 2001-07-15 |
Family
ID=19348264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94903120T ATE202476T1 (de) | 1992-12-31 | 1993-12-31 | Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5916587A (de) |
| EP (1) | EP0676962B9 (de) |
| JP (1) | JP2847578B2 (de) |
| KR (1) | KR100212961B1 (de) |
| AT (1) | ATE202476T1 (de) |
| AU (2) | AU5718494A (de) |
| BR (1) | BR9307754A (de) |
| CA (1) | CA2153166A1 (de) |
| DE (1) | DE69330388T2 (de) |
| ES (1) | ES2160623T3 (de) |
| PT (1) | PT676962E (de) |
| RU (1) | RU2110261C1 (de) |
| WO (1) | WO1994015609A1 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3382032B2 (ja) | 1994-10-14 | 2003-03-04 | 埼玉第一製薬株式会社 | インドメタシン貼付剤 |
| DE19526864A1 (de) * | 1995-07-22 | 1997-01-23 | Labtec Gmbh | Hormonpflaster |
| KR980000439A (ko) * | 1996-06-28 | 1998-03-30 | 김준웅 | 케토프로펜 경피투여 시스템 |
| EP1158967B1 (de) * | 1999-03-01 | 2003-04-16 | Amarin Technologies S.A. | Transdermales system enthaltend nicht-steroidische entzündungshemmer in einer acrylpolymer-klebematrix |
| KR100393478B1 (ko) * | 2000-03-29 | 2003-08-06 | 주식회사종근당 | 자가유화 매트릭스형 경점막·경피흡수제제 |
| US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
| USRE44145E1 (en) | 2000-07-07 | 2013-04-09 | A.V. Topchiev Institute Of Petrochemical Synthesis | Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties |
| ES2331302T3 (es) | 2001-05-01 | 2009-12-29 | A.V. Topchiev Institute Of Petrochemical Synthesis | Composiciones de hidrogel. |
| US8541021B2 (en) | 2001-05-01 | 2013-09-24 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions demonstrating phase separation on contact with aqueous media |
| US20050113510A1 (en) | 2001-05-01 | 2005-05-26 | Feldstein Mikhail M. | Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components |
| US20050215727A1 (en) | 2001-05-01 | 2005-09-29 | Corium | Water-absorbent adhesive compositions and associated methods of manufacture and use |
| EP1390084B1 (de) | 2001-05-01 | 2011-03-23 | A.V. Topchiev Institute of Petrochemical Synthesis | Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung |
| RU2276177C2 (ru) * | 2001-05-01 | 2006-05-10 | Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук | Получение гидрофильных, чувствительных к давлению адгезивов с оптимизированными адгезионными свойствами |
| US8840918B2 (en) | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
| US8206738B2 (en) | 2001-05-01 | 2012-06-26 | Corium International, Inc. | Hydrogel compositions with an erodible backing member |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| US20030175329A1 (en) * | 2001-10-04 | 2003-09-18 | Cellegy Pharmaceuticals, Inc. | Semisolid topical hormonal compositions and methods for treatment |
| US20030124174A1 (en) * | 2001-10-25 | 2003-07-03 | Endo Pharmaceuticals, Inc | Method for treating non-neuropathic pain |
| CA2453013C (en) * | 2002-12-13 | 2011-02-15 | Gary W. Cleary | Dermal, transdermal, mucosal or transmucosal ingredient delivery devices |
| EP1648363B1 (de) * | 2003-07-03 | 2019-03-06 | Corium International, Inc. | Wundverband, vorrichtung zur inhaltsstoffzuführung und iv-hold-down sowie verfahren im zusammenhang damit |
| JP4626202B2 (ja) * | 2003-07-16 | 2011-02-02 | 大正製薬株式会社 | ピロキシカム含有外用消炎鎮痛剤組成物 |
| KR100552650B1 (ko) * | 2003-11-17 | 2006-02-20 | 아이큐어 주식회사 | 피록시캄 함유 소염진통용 플라스터 |
| RU2380092C2 (ru) | 2004-01-30 | 2010-01-27 | Кориум Интернэшнл, Инк. | Быстро растворяющаяся пленка для доставки активного агента |
| WO2005123046A1 (en) * | 2004-06-15 | 2005-12-29 | Amorepacific Corporation | Novel transdermal preparation and its producing method |
| EP1791575B1 (de) * | 2004-08-05 | 2014-10-08 | Corium International, Inc. | Klebstoffzusammensetzung |
| CN102225046A (zh) * | 2005-08-05 | 2011-10-26 | 努沃研究公司 | 透皮释药剂型 |
| KR101402592B1 (ko) * | 2006-03-06 | 2014-06-17 | 에스케이바이오팜 주식회사 | 피록시캄-무기물 복합체를 포함하는 경피투여 조성물 및이를 이용한 패치시스템 |
| KR101304982B1 (ko) * | 2006-05-08 | 2013-09-06 | (주)아모레퍼시픽 | 경피흡수용 조성물 및 이로부터 형성된 고분자 매트릭스함유 경피흡수제제 |
| WO2008001204A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal compositions of pramipexole having enhanced permeation properties |
| KR100835074B1 (ko) * | 2006-09-27 | 2008-06-03 | 조선대학교산학협력단 | 멜록시캄 경피 흡수제 조성물 및 그의 제조 방법 |
| WO2010083035A2 (en) | 2009-01-14 | 2010-07-22 | Corium International, Inc. | Transdermal administration of tamsulosin |
| US8563031B2 (en) | 2010-05-27 | 2013-10-22 | Absize, Inc. | Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith |
| JP5966261B2 (ja) * | 2010-06-17 | 2016-08-10 | 大正製薬株式会社 | 外用組成物 |
| EP2794793B1 (de) * | 2011-12-21 | 2018-11-28 | 3M Innovative Properties Company | Klebepflasteranordnung mit überzug sowie system und verfahren zu ihrer herstellung |
| KR101365321B1 (ko) * | 2012-05-22 | 2014-02-20 | 제일약품주식회사 | 매트릭스내 비스테로이드성 소염진통제의 농도구배를 이용하여 경피투과도를 향상시킨 패취제 |
| KR102009546B1 (ko) | 2012-06-20 | 2019-08-09 | 히사미쓰 세이야꾸 가부시키가이샤 | 첩부제 |
| JP6341091B2 (ja) | 2012-10-17 | 2018-06-13 | 味の素株式会社 | 化粧料組成物 |
| CA2908041C (en) | 2013-04-04 | 2018-05-01 | Hyundai Pharm Co., Ltd. | Composition for external use preparation with improved transdermal permeability |
| DE102014102400A1 (de) * | 2014-02-25 | 2015-08-27 | Reinhard Caliebe | Topische kosmetische oder pharmazeutische Zusammensetzung |
| EP3169318B1 (de) * | 2014-07-18 | 2020-04-01 | Buzzz Pharmaceuticals Limited | Gegen missbrauch gesichertes transdermales system |
| KR102358377B1 (ko) | 2016-12-28 | 2022-02-03 | 히사미쓰 세이야꾸 가부시키가이샤 | 첩부제 |
| TWI781370B (zh) * | 2019-01-31 | 2022-10-21 | 日商久光製藥股份有限公司 | 貼附劑 |
| KR20210133821A (ko) | 2020-04-29 | 2021-11-08 | 신신제약 주식회사 | 피록시캄을 함유하는 경피 흡수 제제 |
| US11872320B2 (en) | 2021-02-25 | 2024-01-16 | Hisamitsu Pharmaceutical Co., Inc. | Method for treating osteoarthritis |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2314731A1 (fr) * | 1975-06-19 | 1977-01-14 | Nelson Res & Dev | Azacycloalcan-2-ones 1-substituees et compositions pharmaceutiques contenant ces composes a titre d'excipients |
| US4440777A (en) * | 1981-07-07 | 1984-04-03 | Merck & Co., Inc. | Use of eucalyptol for enhancing skin permeation of bio-affecting agents |
| US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| DE3586707T2 (de) * | 1984-10-05 | 1993-02-11 | Hercon Lab | System zur transdermalen applikation eines arzneimittels. |
| US5196410A (en) * | 1986-10-31 | 1993-03-23 | Pfizer Inc. | Transdermal flux enhancing compositions |
| MY102980A (en) * | 1986-10-31 | 1993-03-31 | Pfizer | Transdermal flux enhancing compositions |
| JPH0744940B2 (ja) * | 1986-12-24 | 1995-05-17 | ライオン株式会社 | 口腔貼付用基材 |
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| ATE80313T1 (de) * | 1988-02-29 | 1992-09-15 | Pfizer | Mittel zur erhoehung des transdermalen penetrationsflusses. |
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5082866A (en) * | 1988-06-01 | 1992-01-21 | Odontex, Inc. | Biodegradable absorption enhancers |
| DE58906975D1 (de) * | 1988-08-02 | 1994-03-24 | Ciba Geigy | Mehrschichtiges Pflaster. |
| MX21452A (es) * | 1989-07-07 | 1994-01-31 | Ciba Geigy Ag | Preparaciones farmaceuticas que se administran en forma topica. |
| US5262165A (en) * | 1992-02-04 | 1993-11-16 | Schering Corporation | Transdermal nitroglycerin patch with penetration enhancers |
| JP2820306B2 (ja) * | 1990-02-27 | 1998-11-05 | 積水化学工業株式会社 | 経皮吸収製剤 |
-
1993
- 1993-12-31 ES ES94903120T patent/ES2160623T3/es not_active Expired - Lifetime
- 1993-12-31 AT AT94903120T patent/ATE202476T1/de active
- 1993-12-31 CA CA002153166A patent/CA2153166A1/en not_active Abandoned
- 1993-12-31 JP JP6515882A patent/JP2847578B2/ja not_active Expired - Fee Related
- 1993-12-31 KR KR1019930032006A patent/KR100212961B1/ko not_active Expired - Lifetime
- 1993-12-31 PT PT94903120T patent/PT676962E/pt unknown
- 1993-12-31 EP EP94903120A patent/EP0676962B9/de not_active Expired - Lifetime
- 1993-12-31 RU RU95113471A patent/RU2110261C1/ru active
- 1993-12-31 WO PCT/KR1993/000127 patent/WO1994015609A1/en not_active Ceased
- 1993-12-31 DE DE69330388T patent/DE69330388T2/de not_active Expired - Lifetime
- 1993-12-31 BR BR9307754A patent/BR9307754A/pt not_active Application Discontinuation
- 1993-12-31 AU AU57184/94A patent/AU5718494A/en not_active Abandoned
-
1997
- 1997-06-23 AU AU26187/97A patent/AU706123B2/en not_active Ceased
- 1997-10-03 US US08/943,140 patent/US5916587A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT676962E (pt) | 2001-10-30 |
| DE69330388D1 (de) | 2001-08-02 |
| AU2618797A (en) | 1997-09-04 |
| KR100212961B1 (ko) | 1999-08-02 |
| JPH08500365A (ja) | 1996-01-16 |
| AU706123B2 (en) | 1999-06-10 |
| BR9307754A (pt) | 1995-10-24 |
| EP0676962A1 (de) | 1995-10-18 |
| US5916587A (en) | 1999-06-29 |
| DE69330388T2 (de) | 2002-01-03 |
| RU2110261C1 (ru) | 1998-05-10 |
| WO1994015609A1 (en) | 1994-07-21 |
| ES2160623T3 (es) | 2001-11-16 |
| EP0676962B1 (de) | 2001-06-27 |
| AU5718494A (en) | 1994-08-15 |
| JP2847578B2 (ja) | 1999-01-20 |
| CA2153166A1 (en) | 1994-07-21 |
| EP0676962B9 (de) | 2002-04-03 |
| KR940013496A (ko) | 1994-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69330388D1 (de) | Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam | |
| PT99749A (pt) | Processo de preparacao de uma composicao incrementadora da permeacao na pele | |
| FI905718A0 (fi) | Transdermalt medel. | |
| EA199900553A1 (ru) | Чрескожная терапевтическая система | |
| AU7396294A (en) | Incorporating poly-n-vinyl amide in a transdermal system | |
| DK0971705T3 (da) | Lægemiddelformuleringer til hormonerstatningsterapi til lokal påföring på huden | |
| ES2152979T3 (es) | Sistema terapeutico transdermal que contiene estradiol. | |
| FI914391A0 (fi) | Sammansaettningar vilka foerstaerker hudens permeabilitet. | |
| DK0901368T3 (da) | Dermale gennemtrængningsenhancere og lægemiddeladministrationssystemer, der involverer samme | |
| BR9712304A (pt) | Uso de derivados de pirazol1-benzil-3-(hetarila substituìda)-fundidos | |
| ES2184801T3 (es) | Preparacion de parche transdermico de tipo de matriz. | |
| UA41446C2 (uk) | Застосування фумагілолу та його похідних для одержання ліків, призначених для боротьби з кишковими інфекціями, та фармацевтична композиція на їх основі | |
| DK0922453T3 (da) | Tulobuterolholdigt præparat til perkutan absorption | |
| BR0308613A (pt) | Combinação de compostos orgânicos | |
| YU45301A (sh) | Sistemi za oslobađanje leka kroz kožu | |
| KR850004389A (ko) | 경피침투가 증진된 생리학적 활성제제의 제조방법 | |
| YU14394A (sh) | Flaster sa aktivnom supstancom za davanje estradiola na kožu | |
| DE3866408D1 (de) | Selbstklebende vorrichtung zur transdermalen verabreichung eines wirkstoffs. | |
| ATE262333T1 (de) | Scopolaminpflaster | |
| ATE285212T1 (de) | Absorptionsförderer für topische pharmazeutische formulierungen | |
| PT1152751E (pt) | Sistema terapeutico transdermal de desoxipeganina | |
| ATE187776T1 (de) | Chemische verbindungen und pharmazeutische zusammensetzungen zur freisetzung von arzneimitteln | |
| YU3390A (sh) | Postupak za izradu površinskog terapijskog sistema sa sadržajem antineoplastične aktivne materije, naročito 5-fluor-uracila | |
| ATE61522T1 (de) | Pharmazeutische zubereitung zur behandlung von tinea pedis. | |
| DE3881254D1 (de) | Pharmazeutische zusammensetzung. |