ES2184801T3 - Preparacion de parche transdermico de tipo de matriz. - Google Patents

Preparacion de parche transdermico de tipo de matriz.

Info

Publication number
ES2184801T3
ES2184801T3 ES95920235T ES95920235T ES2184801T3 ES 2184801 T3 ES2184801 T3 ES 2184801T3 ES 95920235 T ES95920235 T ES 95920235T ES 95920235 T ES95920235 T ES 95920235T ES 2184801 T3 ES2184801 T3 ES 2184801T3
Authority
ES
Spain
Prior art keywords
type patch
active substance
acid
physiological active
organic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95920235T
Other languages
English (en)
Inventor
Naruhito Higo
Ken Komori
Takaaki Terahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Application granted granted Critical
Publication of ES2184801T3 publication Critical patent/ES2184801T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Botany (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

SE MUESTRA UNA PREPARACION DE PARCHE TIPO MATRIZ QUE INCLUYE UNA CAPA ADHESIVA QUE CONTIENE UNA SUSTANCIA ACTIVA FISIOLOGICAMENTE, UN ACIDO ORGANICO, UN MATERIAL MOLECULAR ALTAMENTE HIDROFOBICO, UNA RESINA DE HILVANADO, UN PLASTIFICADOR Y UN MEJORADOR DE ABSORCION. LA CAPA ADHESIVA PREFERIBLEMENTE CONTIENE DE 0.1 A 20% (W/W) DE LA SUSTANCIA ACTIVA FISIOLOGICA, DEL 0.01 AL 15% (W/W) DE ACIDO ORGANICO, DEL 15 AL 60% (W/W) DE MATERIAL MOLECULAR ALTAMENTE HIDROFOFICO, DEL 10 AL 70% (W/W) DE LA RESINA DE HILVANADO, , DEL 10 AL 60% (W/W) DE PLASTIFICADOR Y DEL 0.01 AL 20% (W/W) DEL MEJORADOR DE ABSORCION. EL ACIDO ORGANICO ES PREFERIBLEMENTE UN ACIDO CARBOXILICO ALIPATICO, UN ACIDO CARBOXILICO AROMATICO, UN DERIVADO DE ACIDO SULFONICO DE ALQUIL, DERIVADO DE ACIDO COLICO O SAL INORGANICA SOLUBLE EN AGUA DE LO ANTERIOR. LA FORMACION DE PARCHE DE TIPO MATRIZ DE ESTA INVENCION PUEDE AUMENTAR LA ABSORBILIDAD PERCUTANEA DE LA SUSTANCIA ACTIVA FISIOLOGICA Y TIENE UNA ESCASA CAPACIDAD PARA PRODUCIR IRRITACION EN LA PIEL.
ES95920235T 1994-11-29 1995-06-01 Preparacion de parche transdermico de tipo de matriz. Expired - Lifetime ES2184801T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31911794A JP3908795B2 (ja) 1994-11-29 1994-11-29 ケトチフェン含有経皮投与製剤

Publications (1)

Publication Number Publication Date
ES2184801T3 true ES2184801T3 (es) 2003-04-16

Family

ID=18106658

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95920235T Expired - Lifetime ES2184801T3 (es) 1994-11-29 1995-06-01 Preparacion de parche transdermico de tipo de matriz.

Country Status (13)

Country Link
US (1) US5866157A (es)
EP (1) EP0788792B1 (es)
JP (1) JP3908795B2 (es)
KR (1) KR100385268B1 (es)
CN (1) CN1065428C (es)
AT (1) ATE229798T1 (es)
AU (1) AU708123B2 (es)
CA (1) CA2206303A1 (es)
DE (1) DE69529228T2 (es)
DK (1) DK0788792T3 (es)
ES (1) ES2184801T3 (es)
PT (1) PT788792E (es)
WO (1) WO1996016642A1 (es)

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BRPI0012401B1 (pt) 1999-07-15 2016-09-27 Hisamitsu Pharmaceutical Co preparação percutaneamente absorvível, e, composição aceleradora da absorção percutânea do medicamento ácido na forma de sal
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Also Published As

Publication number Publication date
JPH08157365A (ja) 1996-06-18
HK1001853A1 (en) 1998-07-17
EP0788792A1 (en) 1997-08-13
AU2575695A (en) 1996-06-19
DK0788792T3 (da) 2003-01-13
CA2206303A1 (en) 1996-06-06
WO1996016642A1 (en) 1996-06-06
EP0788792A4 (en) 1998-05-27
PT788792E (pt) 2003-03-31
EP0788792B1 (en) 2002-12-18
CN1171736A (zh) 1998-01-28
CN1065428C (zh) 2001-05-09
US5866157A (en) 1999-02-02
DE69529228D1 (de) 2003-01-30
KR100385268B1 (ko) 2003-08-19
JP3908795B2 (ja) 2007-04-25
DE69529228T2 (de) 2003-07-17
ATE229798T1 (de) 2003-01-15
AU708123B2 (en) 1999-07-29

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