ATE202486T1 - Biodegradierbare medizinische polymer-anordnung mit supermolekularer-struktur - Google Patents

Biodegradierbare medizinische polymer-anordnung mit supermolekularer-struktur

Info

Publication number
ATE202486T1
ATE202486T1 AT95918178T AT95918178T ATE202486T1 AT E202486 T1 ATE202486 T1 AT E202486T1 AT 95918178 T AT95918178 T AT 95918178T AT 95918178 T AT95918178 T AT 95918178T AT E202486 T1 ATE202486 T1 AT E202486T1
Authority
AT
Austria
Prior art keywords
drug
polymer
supermolecular structure
biodegradable
cyclic compounds
Prior art date
Application number
AT95918178T
Other languages
English (en)
Inventor
Nobuhiko Yui
Nomigun Machi
Original Assignee
Nobuhiko Yui
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nobuhiko Yui filed Critical Nobuhiko Yui
Application granted granted Critical
Publication of ATE202486T1 publication Critical patent/ATE202486T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AT95918178T 1994-09-24 1995-05-12 Biodegradierbare medizinische polymer-anordnung mit supermolekularer-struktur ATE202486T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25487294A JP3699141B2 (ja) 1994-09-24 1994-09-24 超分子構造の生体内分解性医薬高分子集合体及びその調製方法
PCT/JP1995/000909 WO1996009073A1 (en) 1994-09-24 1995-05-12 Biodegradable medicinal polymer assembly with supermolecular structure

Publications (1)

Publication Number Publication Date
ATE202486T1 true ATE202486T1 (de) 2001-07-15

Family

ID=17271012

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95918178T ATE202486T1 (de) 1994-09-24 1995-05-12 Biodegradierbare medizinische polymer-anordnung mit supermolekularer-struktur

Country Status (10)

Country Link
US (1) US5855900A (de)
EP (1) EP0730869B1 (de)
JP (1) JP3699141B2 (de)
KR (1) KR100387428B1 (de)
CN (1) CN1135720A (de)
AT (1) ATE202486T1 (de)
AU (1) AU2419995A (de)
CA (1) CA2176383A1 (de)
DE (1) DE69521491T2 (de)
WO (1) WO1996009073A1 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19629494A1 (de) * 1996-07-09 1998-01-15 Schering Ag Pseudopolyrotaxane
JP2972861B2 (ja) * 1997-05-08 1999-11-08 北陸先端科学技術大学院大学長 超分子構造の血液適合性材料
US6730735B2 (en) * 1997-07-03 2004-05-04 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Conjugate of polyethylene glycol and chitosan
US6113880A (en) * 1997-12-17 2000-09-05 Schering Aktiengesellschaft Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging
US7091192B1 (en) * 1998-07-01 2006-08-15 California Institute Of Technology Linear cyclodextrin copolymers
US6509323B1 (en) 1998-07-01 2003-01-21 California Institute Of Technology Linear cyclodextrin copolymers
EP1133318B1 (de) * 1998-12-04 2007-03-14 California Institute of Technology Supramolekulare komplexe enthaltende arzneimittel
US7375096B1 (en) * 1998-12-04 2008-05-20 California Institute Of Technology Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network
SG98393A1 (en) * 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
CN1208094C (zh) * 2000-07-03 2005-06-29 株式会社日本组织工程 组织再生用基材、移植用材料及其制法
GB0018072D0 (en) * 2000-07-25 2000-09-13 Smith & Nephew Biodegradable supramolecular assemblies
TWI321054B (en) * 2000-12-19 2010-03-01 California Inst Of Techn Compositions containing inclusion complexes
US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US7141540B2 (en) * 2001-11-30 2006-11-28 Genta Salus Llc Cyclodextrin grafted biocompatible amphilphilic polymer and methods of preparation and use thereof
US20030216315A1 (en) 2002-02-13 2003-11-20 Duke University Modulation of immune response by non-peptide binding stress response polypeptides
US20030171573A1 (en) * 2002-02-27 2003-09-11 Nobuhiko Yui Multivalently interactive molecular assembly, capturing agent, drug carrier, calcium chelating agent, and drug enhancer
US20040162275A1 (en) * 2002-02-27 2004-08-19 Nobuhiko Yui Multivalently interactive molecular assembly, capturing agent, drug carrier, calcium chelating agent, and drug enhancer
ES2377318T3 (es) 2002-09-06 2012-03-26 Cerulean Pharma Inc. Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
CA2500661A1 (en) * 2002-10-01 2004-04-15 Chiron Corporation Anti-cancer and anti-infectious disease compositions and methods for using same
KR20050051686A (ko) * 2002-10-09 2005-06-01 인설트 테라페틱스, 인코퍼레이티드 사이클로덱스트린-기초한 재료, 조성물 및 이의 용도
JP5070671B2 (ja) * 2003-04-25 2012-11-14 東レ株式会社 親水性材料およびその製造方法
WO2005004795A2 (en) * 2003-06-09 2005-01-20 University Of Cincinnati Compositions and methods for targeted drug delivery
JP4747256B2 (ja) * 2003-11-04 2011-08-17 Jnc株式会社 複合刺激応答材料
US20050118124A1 (en) * 2003-12-01 2005-06-02 Reinhart Gale M. Compositions for treating keratinous surfaces
JP4913030B2 (ja) 2005-01-31 2012-04-11 株式会社バイオセレンタック 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具
US7883688B2 (en) * 2005-02-03 2011-02-08 Agency For Science, Technology And Research Polycationic polyrotaxanes capable of forming complexes with nucleic acids
ES2277743B2 (es) 2005-06-02 2008-12-16 Universidade De Santiago De Compostela Nanoparticulas que comprenden quitosano y ciclodextrina.
WO2007016757A1 (en) * 2005-08-05 2007-02-15 Orbus Pharma Inc. Stabilized extended release pharmeceutical compositions comprising an hmg-coa reductase inhibitor
JP4521875B2 (ja) * 2005-08-31 2010-08-11 日産自動車株式会社 疎水性修飾ポリロタキサン
US20080026062A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Pharmaceutical compositions including nano-sized active agent
US20080026040A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Active agent-releasing dosage forms
KR100793268B1 (ko) 2006-10-02 2008-01-10 부산대학교 산학협력단 복합체의 제조방법
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
WO2010042815A2 (en) * 2008-10-09 2010-04-15 Duke University Vhh antibody fragments for use in the detection and treatment of cancer
US20100168044A1 (en) * 2008-12-26 2010-07-01 Devesh Kumar Misra Superparamagnetic nanoparticle encapsulated with stimuli responsive polymer for drug delivery
US8518405B2 (en) 2009-10-08 2013-08-27 The University Of North Carolina At Charlotte Tumor specific antibodies and uses therefor
CN102781237A (zh) * 2009-11-23 2012-11-14 天蓝制药公司 用于传递治疗剂的基于环糊精的聚合物
US20110300150A1 (en) * 2010-05-18 2011-12-08 Scott Eliasof Compositions and methods for treatment of autoimmune and other disease
US9376486B2 (en) 2010-12-14 2016-06-28 National University Of Singapore Human monoclonal antibody with specificity for Dengue virus serotype 1 E protein and uses thereof
ES2552210T3 (es) 2010-12-16 2015-11-26 Sumitomo Seika Chemicals Co., Ltd. Método para la producción de un pseudopolirrotaxano
WO2012081432A1 (ja) * 2010-12-16 2012-06-21 住友精化株式会社 精製ポリロタキサンの製造方法
CA2821905C (en) 2010-12-16 2018-07-10 Sumitomo Seika Chemicals Co., Ltd. Method for producing pseudopolyrotaxane aqueous dispersion
WO2012081430A1 (ja) 2010-12-16 2012-06-21 住友精化株式会社 擬ポリロタキサンの製造方法
CN103403032B (zh) * 2011-03-14 2016-04-20 住友精化株式会社 粉末状亲水性改性聚轮烷的制造方法
CA2829854C (en) * 2011-03-14 2017-10-24 Sumitomo Seika Chemicals Production method for hydrophilic modified polyrotaxane
US9266972B2 (en) * 2011-03-14 2016-02-23 Sumitomo Seika Chemicals Co., Ltd. Polyrotaxane composition
WO2013147300A1 (ja) * 2012-03-30 2013-10-03 宇部興産株式会社 ヒドロキシアルキル化ポリロタキサンの製造方法
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
WO2015183346A2 (en) 2014-01-31 2015-12-03 Washington University Imaging and treatment of pathophysiologic conditions by cerenkov radiation
US9974870B2 (en) 2014-06-09 2018-05-22 Washington University Compositions and methods for treatment and imaging using nanoparticles
US10329386B2 (en) * 2014-07-08 2019-06-25 Osaka University Self-restoring macromolecular material and production method for same
CA2956161A1 (en) 2014-07-23 2016-01-28 Ohio State Innovation Foundation Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (tag-72)
EP3172222A4 (de) 2014-07-24 2018-03-21 Washington University Gegen strahlungsinduzierte moleküle gerichtete zusammensetzungen und verfahren zur verwendung davon
WO2016196604A1 (en) 2015-06-04 2016-12-08 The University Of Florida Research Foundation, Inc. Electroactive supramolecular polymeric assemblies, methods of making electroactive supramolecular polymeric assemblies, and methods of using electroactive supramolecular polymeric assemblies
EP3347380B1 (de) 2015-09-11 2024-09-25 Nascent Biotech, Inc. Verbesserte abgabe von medikamenten an das gehirn
WO2017079537A1 (en) 2015-11-04 2017-05-11 Duke University Polycationic polymers for use in treating and detecting cancer
US12447464B2 (en) 2016-12-22 2025-10-21 Duke University Polycationic microfibers and methods of using the same
US12319967B2 (en) 2019-08-21 2025-06-03 University Of Virginia Patent Foundation Methods and compositions for diagnosing and treating prostate cancer based on long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth
US11788091B2 (en) 2019-08-21 2023-10-17 University Of Virginia Patent Foundation Methods and compositions for diagnosing and treating prostate cancer based on long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth
JP7630158B2 (ja) * 2020-02-20 2025-02-17 国立大学法人 東京大学 ポリマー-環状分子構造体及びその製造方法
EP4232605A4 (de) 2020-11-11 2024-09-25 University of Virginia Patent Foundation Verfahren und zusammensetzungen zur diagnose und behandlung von prostatakrebs auf basis von langer nichtcodierender rna, die das lck-gen überlappen, das prostatakrebszellwachstum reguliert
EP4356929A1 (de) * 2022-10-19 2024-04-24 Universität Rostock Antifibrotische formulierung zur ophthalmischen behandlung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60112713A (ja) * 1983-11-21 1985-06-19 Sumitomo Chem Co Ltd 有用な徐放性注射剤
JPS6089418A (ja) * 1983-10-20 1985-05-20 Sumitomo Chem Co Ltd 徐放性制癌剤
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates

Also Published As

Publication number Publication date
CN1135720A (zh) 1996-11-13
WO1996009073A1 (en) 1996-03-28
DE69521491T2 (de) 2002-03-28
CA2176383A1 (en) 1996-03-28
EP0730869B1 (de) 2001-06-27
KR100387428B1 (ko) 2003-10-04
EP0730869A4 (de) 1999-06-16
EP0730869A1 (de) 1996-09-11
US5855900A (en) 1999-01-05
JPH0892130A (ja) 1996-04-09
DE69521491D1 (de) 2001-08-02
JP3699141B2 (ja) 2005-09-28
AU2419995A (en) 1996-04-09

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