ATE203523T1 - Optisch aktive phenylpyrimidin-derivat als schmerzlinderndes mittel - Google Patents

Optisch aktive phenylpyrimidin-derivat als schmerzlinderndes mittel

Info

Publication number
ATE203523T1
ATE203523T1 AT96931006T AT96931006T ATE203523T1 AT E203523 T1 ATE203523 T1 AT E203523T1 AT 96931006 T AT96931006 T AT 96931006T AT 96931006 T AT96931006 T AT 96931006T AT E203523 T1 ATE203523 T1 AT E203523T1
Authority
AT
Austria
Prior art keywords
optically active
pain relief
phenylpyrimidine derivative
active phenylpyrimidine
derivative
Prior art date
Application number
AT96931006T
Other languages
English (en)
Inventor
Malcolm Stuart Nobbs
Sandra Jane Rodgers
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE203523T1 publication Critical patent/ATE203523T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96931006T 1995-09-05 1996-09-03 Optisch aktive phenylpyrimidin-derivat als schmerzlinderndes mittel ATE203523T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9518027.9A GB9518027D0 (en) 1995-09-05 1995-09-05 Pharmacologically active compound
PCT/EP1996/003856 WO1997009317A2 (en) 1995-09-05 1996-09-03 Optically active phenyl pyrimidine derivative as analgesic agent

Publications (1)

Publication Number Publication Date
ATE203523T1 true ATE203523T1 (de) 2001-08-15

Family

ID=10780172

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96931006T ATE203523T1 (de) 1995-09-05 1996-09-03 Optisch aktive phenylpyrimidin-derivat als schmerzlinderndes mittel

Country Status (32)

Country Link
US (1) US6124308A (de)
EP (1) EP0879230B1 (de)
JP (1) JPH11512108A (de)
KR (1) KR19990044397A (de)
CN (1) CN1200729A (de)
AP (1) AP640A (de)
AR (1) AR004192A1 (de)
AT (1) ATE203523T1 (de)
AU (1) AU710091B2 (de)
BG (1) BG65102B1 (de)
BR (1) BR9610388A (de)
CA (1) CA2230362A1 (de)
CO (1) CO4750651A1 (de)
CZ (1) CZ65598A3 (de)
DE (1) DE69614150T2 (de)
EA (1) EA000695B1 (de)
ES (1) ES2160834T3 (de)
GB (1) GB9518027D0 (de)
HR (1) HRP960399A2 (de)
HU (1) HUP9901260A3 (de)
ID (1) ID17274A (de)
IL (1) IL123414A0 (de)
IS (1) IS4673A (de)
NO (1) NO980923L (de)
NZ (1) NZ318390A (de)
PL (1) PL325329A1 (de)
SK (1) SK28598A3 (de)
TR (1) TR199800386T1 (de)
TW (1) TW367326B (de)
WO (1) WO1997009317A2 (de)
YU (1) YU49796A (de)
ZA (1) ZA967466B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR016212A1 (es) * 1998-04-28 2001-06-20 Astra Ab Uso de compuestos farmaceuticos que tienen una actividad antagonista de nmda para preparar un medicamento para el tratamiento del sindrome de intestino irritable (ibs), y composiciones farmaceuticas
EP1085890A1 (de) * 1998-06-08 2001-03-28 Advanced Medicine, Inc. Neuartige natriumkanal-medikamente und deren verwendungen
US6420354B1 (en) 1998-06-08 2002-07-16 Advanced Medicine, Inc. Sodium channel drugs and uses
GB9907965D0 (en) * 1999-04-09 1999-06-02 Glaxo Group Ltd Medical use
US6479498B1 (en) 1999-06-04 2002-11-12 Theravance, Inc. Sodium channel drugs and uses
PL365701A1 (en) * 2000-07-21 2005-01-10 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
CA2439468A1 (en) 2001-02-27 2002-09-06 Teva Pharmaceutical Industries Ltd. New crystal forms of lamotrigine and processes for their preparations
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
WO2003090693A2 (en) * 2002-04-23 2003-11-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing lamotrigine particles of defined morphology
CA2514574A1 (en) * 2003-01-30 2004-08-12 Dynogen Pharmaceuticals, Inc. Use of sodium channel modulators for treating gastrointestinal tract disorders
GB0603087D0 (en) * 2006-02-15 2006-03-29 Glaxo Group Ltd Novel use
US8093268B2 (en) 2007-01-24 2012-01-10 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl-benzyl)-(2S-phenylpiperidin-3S-yl-)
GB201111712D0 (en) 2011-07-08 2011-08-24 Gosforth Ct Holdings Pty Ltd Pharmaceutical compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL124029B1 (en) * 1979-06-01 1982-12-31 Wellcome Found Process for preparing novel derivatives of 1,2,4-triazine
FI895821A7 (fi) * 1988-12-07 1990-06-08 The Wellcome Foundation Ltd Farmaseuttisesti aktivisia CNS-yhdisteitä

Also Published As

Publication number Publication date
DE69614150D1 (de) 2001-08-30
PL325329A1 (en) 1998-07-20
WO1997009317A3 (en) 1997-04-03
KR19990044397A (ko) 1999-06-25
WO1997009317A2 (en) 1997-03-13
ID17274A (id) 1997-12-18
TR199800386T1 (xx) 1998-05-21
ZA967466B (en) 1998-04-06
BG102342A (en) 1998-09-30
EP0879230A2 (de) 1998-11-25
JPH11512108A (ja) 1999-10-19
NO980923D0 (no) 1998-03-04
TW367326B (en) 1999-08-21
IL123414A0 (en) 1998-09-24
CA2230362A1 (en) 1997-03-13
NZ318390A (en) 1999-02-25
EA199800189A1 (ru) 1998-10-29
AU6986596A (en) 1997-03-27
AP640A (en) 1998-04-14
HUP9901260A2 (hu) 1999-09-28
DE69614150T2 (de) 2001-11-22
CZ65598A3 (cs) 1998-07-15
ES2160834T3 (es) 2001-11-16
BG65102B1 (bg) 2007-02-28
US6124308A (en) 2000-09-26
HUP9901260A3 (en) 2001-04-28
IS4673A (is) 1998-02-23
NO980923L (no) 1998-05-04
CO4750651A1 (es) 1999-03-31
EA000695B1 (ru) 2000-02-28
AR004192A1 (es) 1998-11-04
HRP960399A2 (en) 1998-04-30
YU49796A (sh) 1999-07-28
EP0879230B1 (de) 2001-07-25
MX9801680A (es) 1998-05-31
AP9600857A0 (en) 1996-10-31
AU710091B2 (en) 1999-09-16
GB9518027D0 (en) 1995-11-08
SK28598A3 (en) 1998-09-09
BR9610388A (pt) 1999-07-06
CN1200729A (zh) 1998-12-02

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Legal Events

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