ATE204272T1 - Neue pyridon carbonsäure-derivate - Google Patents

Neue pyridon carbonsäure-derivate

Info

Publication number: ATE204272T1
Authority: AT; Austria
Prior art keywords: group; lower alkyl; hydrogen atom; substituted; acid derivatives
Prior art date: 1992-12-30

Application number

AT94903116T

Other languages

English (en)

Inventor

Choong Sup Kim

Jin Woong Kim

Seongnami-Shi

Jae Mok Lee

Il Hwan Cho

Yong Sik Youn

Young Jun Shin

Ki Ho Lee

Je Hak Kim

Yong Hwan Jung

Seoung Ho An

Original Assignee

Cheil Jedang Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-30

Filing date

1993-12-29

Publication date

2001-09-15

1993-12-29 Application filed by Cheil Jedang Corp filed Critical Cheil Jedang Corp

2001-09-15 Application granted granted Critical

2001-09-15 Publication of ATE204272T1 publication Critical patent/ATE204272T1/de

Links

239000002253 acid Substances 0.000 title 1
LVWZTYCIRDMTEY-UHFFFAOYSA-N metamizole Chemical compound O=C1C(N(CS(O)(=O)=O)C)=C(C)N(C)N1C1=CC=CC=C1 LVWZTYCIRDMTEY-UHFFFAOYSA-N 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
125000000217 alkyl group Chemical group 0.000 abstract 6
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000003277 amino group Chemical group 0.000 abstract 2
YSLIPUSJNFIFAB-UHFFFAOYSA-N 2-oxopyridine-1-carboxylic acid Chemical class OC(=O)N1C=CC=CC1=O YSLIPUSJNFIFAB-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT94903116T 1992-12-30 1993-12-29 Neue pyridon carbonsäure-derivate ATE204272T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR920026696		1992-12-30
KR930011125		1993-06-17
PCT/KR1993/000123 WO1994015933A1 (en)	1992-12-30	1993-12-29	Novel pyridone carboxylic acid derivatives

Publications (1)

Publication Number	Publication Date
ATE204272T1 true ATE204272T1 (de)	2001-09-15

Family

ID=26629459

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94903116T ATE204272T1 (de)	1992-12-30	1993-12-29	Neue pyridon carbonsäure-derivate

Country Status (14)

Country	Link
US (2)	US5527910A (de)
EP (1)	EP0677050B1 (de)
JP (1)	JP2948660B2 (de)
CN (1)	CN1042632C (de)
AT (1)	ATE204272T1 (de)
AU (2)	AU689089B2 (de)
CA (2)	CA2226406C (de)
DE (1)	DE69330612D1 (de)
HU (1)	HU219581B (de)
MX (1)	MX9400113A (de)
NO (2)	NO307883B1 (de)
RU (1)	RU2161154C2 (de)
WO (1)	WO1994015933A1 (de)
YU (1)	YU83993A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100236852B1 (ko) *	1992-10-09	2000-03-02	나가야마 오사무	플루오로 퀴놀린 유도체
US5527910A (en) *	1992-12-30	1996-06-18	Cheil Foods & Chemicals, Inc.	Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
PT812838E (pt) *	1994-02-04	2002-10-31	Dainippon Pharmaceutical Co	Derivado de acido piridonacarboxilico substituido com o grupo amino biciclico seu ester seu sal e amina biciclica como seu intermediario
CN1090185C (zh) *	1995-02-02	2002-09-04	大日本制药株式会社	有双环氨基取代的吡啶酮羧酸衍生物,其酯及盐,以及可用作其中间体的双环类胺
US6218563B1 (en)	1998-12-03	2001-04-17	Monsanto Company	Cyanophosphonamides and method for preparation
HK1044476B (zh)	1999-03-17	2010-09-17	第一制药株式会社	药物组合物
AU2003245442B2 (en) *	2002-06-13	2009-02-05	Vertex Pharmaceuticals Incorporated	2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase IV inhibitors for the treatment of bacterial infections
US7334538B1 (en) *	2004-07-27	2008-02-26	Aquascience Research Group, Inc.	Topical medicants for aquatic animals
CA2663044C (en) *	2006-10-06	2012-07-24	Bausch & Lomb Incorporated	Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US8252783B2 (en)	2007-01-24	2012-08-28	Bausch & Lomb Incorporated	Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US7632944B2 (en) *	2007-01-24	2009-12-15	Bausch & Lomb Incorporated	Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
US7902227B2 (en)	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
BRPI1010981A2 (pt)	2009-05-15	2018-12-04	Redx Pharma Ltd	"derivados de fármaco redox"
PH12013501800A1 (en)	2011-03-15	2013-10-14	L Livermore Nat Security Llc	Tricyclic gyrase inhibitors
JP6075736B2 (ja) *	2011-12-21	2017-02-08	ジエンスヘンルイメデイシンカンパニーリミテッドＪｉａｎｇｓｕＨｅｎｇｒｕｉＭｅｄｉｃｉｎｅＣｏ．，Ｌｔｄ．	ピロール−６員ヘテロアリール環誘導体、その合成法およびその医薬用途
WO2014043272A1 (en)	2012-09-12	2014-03-20	Trius Therapeutics Inc.	Tricyclic gyrase inhibitors for use as antibacterial agents

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3252972A (en) *	1959-11-10	1966-05-24	Ciba Geigy Corp	(n, n-bicycloalkylene-imino)-lower alkyl-guanidines
US3246027A (en) *	1961-03-22	1966-04-12	Du Pont	Process for converting cis-1, 2-dicyanocy-clobutane to trans-1, 2-dicyanocyclobutane
US3246006A (en) *	1963-08-07	1966-04-12	Du Pont	2-(3-azabicyclo [3.2.0] hept-3-ylthio) benothiazole
NL6504082A (de) *	1965-03-31	1966-10-03
US3639390A (en) *	1966-12-30	1972-02-01	Ciba Ltd	Azabicycloalkane derivatives
US3875154A (en) *	1972-09-15	1975-04-01	Univ Ca	Certain 5-thia-1-azabicyclo{8 4.2.0{9 octenes
EP0022288A3 (de) *	1979-07-06	1981-07-01	Shell Internationale Researchmaatschappij B.V.	Verfahren zum Sterilisieren männlicher Staubbeutel in Pflanzen, zur Verwendung in einem solchen Verfahren geeignete Zusammensetzungen und Verbindungen und Verfahren zur Herstellung von F1-gekreuzten Saatgütern
JPS5649382A (en) *	1979-09-28	1981-05-02	Dainippon Pharmaceut Co Ltd	6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4382937A (en) *	1981-02-27	1983-05-10	Dainippon Pharmaceutical Co., Ltd.	Naphthyridine derivatives and their use as anti-bacterials
US4431661A (en) *	1981-08-20	1984-02-14	American Cyanamid Company	5-Aryl-3-azabicyclo[3.2.0]heptan-6-one acetals, and analgesic use therefor
US4571396A (en) *	1984-04-16	1986-02-18	Warner-Lambert Company	Antibacterial agents
JPH0635458B2 (ja) *	1985-02-15	1994-05-11	大日本製薬株式会社	ピリドンカルボン酸誘導体、そのエステルおよびその塩
IL77846A (en) *	1985-03-25	1989-08-15	Warner Lambert Co	Process for the preparation of 7-amino-quinolin-4-oxy-3-carboxylic acid derivatives
JPS62215572A (ja) *	1986-03-17	1987-09-22	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体
US4962108A (en) *	1987-07-31	1990-10-09	Warner-Lambert Company	Antibacterial quinoline compounds
JPH0676400B2 (ja) *	1987-08-25	1994-09-28	大日本製薬株式会社	新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
FR2625200A1 (en) *	1987-12-29	1989-06-30	Esteve Labor Dr	7-(1-Azetidinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their application as medicaments
JP2844079B2 (ja) *	1988-05-23	1999-01-06	塩野義製薬株式会社	ピリドンカルボン酸系抗菌剤
JPH0262875A (ja) *	1988-05-23	1990-03-02	Wakunaga Pharmaceut Co Ltd	新規イソインドリン誘導体
US5147873A (en) *	1988-08-23	1992-09-15	Pfizer Inc.	Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
WO1990002123A1 (en) *	1988-08-23	1990-03-08	Pfizer Inc.	Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
CA1336090C (en) *	1988-08-31	1995-06-27	Isao Hayakawa	Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) *	1988-08-31	1994-02-15	Daiichi Seiyaku Co., Ltd.	Spiro compound
PL166381B1 (pl) *	1989-08-16	1995-05-31	Pfizer	Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
US5164402A (en) *	1989-08-16	1992-11-17	Pfizer Inc	Azabicyclo quinolone and naphthyridinone carboxylic acids
CA2030217A1 (en) *	1989-11-21	1991-05-22	Jun Imose	Pyridone-carboxylic acid derivatives useful as veterinary medicines
CA2076982A1 (en) *	1990-12-27	1992-06-28	Akira Okura	Pyridonecarboxylic acid derivatives
DE4120646A1 (de) *	1991-06-22	1992-12-24	Bayer Ag	7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
EP0549857A1 (de) *	1991-12-31	1993-07-07	Korea Research Institute Of Chemical Technology	Chinolone Carbonsäurederivate verwendbar als antibakterielles Mittel
DE4219973A1 (de) *	1992-06-19	1993-12-23	Basf Ag	N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5527910A (en) *	1992-12-30	1996-06-18	Cheil Foods & Chemicals, Inc.	Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria

1993
- 1993-12-03 US US08/160,821 patent/US5527910A/en not_active Expired - Fee Related
- 1993-12-29 RU RU95115237/04A patent/RU2161154C2/ru active
- 1993-12-29 DE DE69330612T patent/DE69330612D1/de not_active Expired - Lifetime
- 1993-12-29 HU HU9501727A patent/HU219581B/hu not_active IP Right Cessation
- 1993-12-29 CA CA002226406A patent/CA2226406C/en not_active Expired - Fee Related
- 1993-12-29 WO PCT/KR1993/000123 patent/WO1994015933A1/en not_active Ceased
- 1993-12-29 JP JP6515880A patent/JP2948660B2/ja not_active Expired - Lifetime
- 1993-12-29 AU AU57181/94A patent/AU689089B2/en not_active Ceased
- 1993-12-29 AT AT94903116T patent/ATE204272T1/de not_active IP Right Cessation
- 1993-12-29 EP EP94903116A patent/EP0677050B1/de not_active Expired - Lifetime
- 1993-12-29 CA CA002152817A patent/CA2152817C/en not_active Expired - Fee Related
- 1993-12-30 YU YU83993A patent/YU83993A/sh unknown
- 1993-12-30 CN CN93115335A patent/CN1042632C/zh not_active Expired - Fee Related
1994
- 1994-01-03 MX MX9400113A patent/MX9400113A/es not_active IP Right Cessation
1995
- 1995-06-29 NO NO952610A patent/NO307883B1/no not_active IP Right Cessation
1996
- 1996-01-26 US US08/592,171 patent/US5688965A/en not_active Expired - Fee Related
1997
- 1997-09-24 AU AU39220/97A patent/AU704969B2/en not_active Ceased
1999
- 1999-11-17 NO NO995638A patent/NO309087B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU9501727D0 (en)	1995-08-28
AU704969B2 (en)	1999-05-13
CA2226406A1 (en)	1994-07-21
CA2152817A1 (en)	1994-07-21
US5527910A (en)	1996-06-18
AU689089B2 (en)	1998-03-26
CN1098103A (zh)	1995-02-01
CN1042632C (zh)	1999-03-24
HUT72434A (en)	1996-04-29
JP2948660B2 (ja)	1999-09-13
NO995638D0 (no)	1999-11-17
WO1994015933A1 (en)	1994-07-21
NO309087B1 (no)	2000-12-11
CA2226406C (en)	2001-08-14
AU5718194A (en)	1994-08-15
NO995638L (no)	1999-11-17
EP0677050B1 (de)	2001-08-16
AU3922097A (en)	1997-12-18
US5688965A (en)	1997-11-18
JPH08505384A (ja)	1996-06-11
NO307883B1 (no)	2000-06-13
HU219581B (hu)	2001-05-28
MX9400113A (es)	1994-07-29
DE69330612D1 (de)	2001-09-20
EP0677050A1 (de)	1995-10-18
RU2161154C2 (ru)	2000-12-27
NO952610D0 (no)	1995-06-29
NO952610L (no)	1995-08-29
CA2152817C (en)	1998-12-29
RU95115237A (ru)	1997-06-10
YU83993A (sh)	1996-10-09

Legal Events

Date	Code	Title	Description
2002-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69330612D1 (de)	2001-09-20	Neue pyridon carbonsäure-derivate
DK0870765T3 (da)	2004-02-23	Aminothiazolderivat, lægemiddel indeholdende samme og mellemprodukt til fremstilling af forbindelsen
PT705833E (pt)	2004-11-30	Derivado de dc-89
CA2173150A1 (en)	1995-04-13	Novel peptide derivatives
DE69919897D1 (en)	2004-10-07	4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel
ES8707223A1 (es)	1987-07-16	Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofen.
MX9300222A (es)	1993-07-01	Nuevos derivados de arilcicloalquilo, su preparacion y su utilizacion.
FI940414A0 (fi)	1994-01-27	Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö
CA2114727A1 (en)	1993-02-18	Quinoline Derivatives as Immunostimulants
MX9604398A (es)	1997-09-30	Derivados de sulfonamida.
FI914187A0 (fi)	1991-09-05	Menetelmä valmistaa kaavan /I/ mukaista 1-metyylikarbapeneemijohdosta
ATE215937T1 (de)	2002-04-15	Oxazolidinedion-derivate und ihre anwendung als hypoglykämisches mittel
WO2002000638A3 (en)	2002-05-23	Substituted phthalides as anti-convulsive drugs
DK0591058T3 (da)	1999-03-22	Ellipticinderivater med antitumoraktivitet
ES2120498T3 (es)	1998-11-01	Nuevo compuesto tetraciclico.
GR3023757T3 (en)	1997-09-30	Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents.
ES2178642T3 (es)	2003-01-01	Nuevos derivados de piridil-y pirimidil-piperazina.
ATE123025T1 (de)	1995-06-15	2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
DE69217148D1 (de)	1997-03-13	Isoxazole derivate als lichtschutzmittel
ATE129702T1 (de)	1995-11-15	Sulfonamidderivat und dieses enthaltende arzneimittel.
MY131175A (en)	2007-07-31	Heterocyclic compounds