ATE204473T1 - Pharmazeutische zusammensetzung, die gamma- hydroxybuttersäure oder das entsprechende lakton enthält, zur behandlung von drogenabhängigkeit und ernährungsstörungen - Google Patents
Pharmazeutische zusammensetzung, die gamma- hydroxybuttersäure oder das entsprechende lakton enthält, zur behandlung von drogenabhängigkeit und ernährungsstörungenInfo
- Publication number
- ATE204473T1 ATE204473T1 AT92912485T AT92912485T ATE204473T1 AT E204473 T1 ATE204473 T1 AT E204473T1 AT 92912485 T AT92912485 T AT 92912485T AT 92912485 T AT92912485 T AT 92912485T AT E204473 T1 ATE204473 T1 AT E204473T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- hydroxybutry
- acid
- pharmaceutical composition
- composition containing
- Prior art date
Links
- 208000030212 nutrition disease Diseases 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 206010013663 drug dependence Diseases 0.000 title 1
- 150000002596 lactones Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000011117 substance-related disease Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 abstract 1
- 235000019788 craving Nutrition 0.000 abstract 1
- 239000004081 narcotic agent Substances 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 229940001470 psychoactive drug Drugs 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911791A IT1248588B (it) | 1991-06-28 | 1991-06-28 | Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. |
| PCT/EP1992/001409 WO1993000083A1 (en) | 1991-06-28 | 1992-06-23 | Pharmaceutical composition containing gamma-hydroxybutyric acid or its lactone in the treatment of drug dependence and nutritional disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE204473T1 true ATE204473T1 (de) | 2001-09-15 |
Family
ID=11360230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92912485T ATE204473T1 (de) | 1991-06-28 | 1992-06-23 | Pharmazeutische zusammensetzung, die gamma- hydroxybuttersäure oder das entsprechende lakton enthält, zur behandlung von drogenabhängigkeit und ernährungsstörungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5426120A (de) |
| EP (1) | EP0563336B1 (de) |
| AT (1) | ATE204473T1 (de) |
| AU (1) | AU2018792A (de) |
| DE (1) | DE69232016T2 (de) |
| IT (1) | IT1248588B (de) |
| WO (1) | WO1993000083A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234947A (en) * | 1991-11-07 | 1993-08-10 | New York University | Potassium channel activating compounds and methods of use thereof |
| IT1266565B1 (it) | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
| IT1283782B1 (it) * | 1996-08-09 | 1998-04-30 | Ct Lab Farm Srl | Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo |
| CA2355293C (en) | 1998-12-23 | 2005-08-16 | Orphan Medical, Inc. | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy |
| DE60007078T2 (de) * | 1999-02-01 | 2004-12-16 | Ortho-Mcneil Pharmaceutical, Inc. | Verwendung von antikonvulsiven derivaten zur behandlung von bulimia nervosa |
| RU2210360C1 (ru) * | 2002-09-19 | 2003-08-20 | Общество С Ограниченной Ответственностью "Консорциум-Пик" | Психотропное средство |
| US8193211B2 (en) * | 2004-09-30 | 2012-06-05 | Supernus Pharmaceuticals, Inc. | Controlled release compositions of gamma-hydroxybutyrate |
| FR2938431B1 (fr) * | 2008-11-14 | 2013-12-20 | Debregeas Et Associes Pharma | Nouvelle composition a base d'acide gamma-hydroxybutyrique |
| EP2421808B1 (en) | 2009-04-23 | 2013-07-31 | Concert Pharmaceuticals Inc. | 4-hydroxybutyric acid analogs |
| FR2949061B1 (fr) | 2009-08-12 | 2013-04-19 | Debregeas Et Associes Pharma | Microgranules flottants |
| FR2949062B1 (fr) | 2009-08-12 | 2011-09-02 | Debregeas Et Associes Pharma | Nouvelles formulations pharmaceutiques contre le mesusage des medicaments |
| KR101976218B1 (ko) * | 2011-02-14 | 2019-05-07 | 콘서트 파마슈티컬즈, 인크. | 4-히드록시부티르산 중수소화 유사체 |
| US11000498B2 (en) | 2016-07-22 | 2021-05-11 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| EP3930702A1 (de) | 2019-03-01 | 2022-01-05 | Flamel Ireland Limited | Gamma-hydroxybutyratzusammensetzungen mit verbesserter pharmakokinetik im zugeführten zustand |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD139519A1 (de) * | 1978-11-10 | 1980-01-09 | Annedore Wehl | Verfahren zur herstellung analgetischer formulierungen mit verbesserten gebrauchswerteigenschaften |
| IT1217783B (it) * | 1988-06-03 | 1990-03-30 | Farmaceutico Ct S R L Lab | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
-
1991
- 1991-06-28 IT ITMI911791A patent/IT1248588B/it active IP Right Grant
-
1992
- 1992-06-23 AU AU20187/92A patent/AU2018792A/en not_active Abandoned
- 1992-06-23 WO PCT/EP1992/001409 patent/WO1993000083A1/en not_active Ceased
- 1992-06-23 AT AT92912485T patent/ATE204473T1/de not_active IP Right Cessation
- 1992-06-23 EP EP92912485A patent/EP0563336B1/de not_active Expired - Lifetime
- 1992-06-23 US US08/081,388 patent/US5426120A/en not_active Expired - Lifetime
- 1992-06-23 DE DE69232016T patent/DE69232016T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT1248588B (it) | 1995-01-19 |
| ITMI911791A0 (it) | 1991-06-28 |
| DE69232016T2 (de) | 2002-05-29 |
| US5426120A (en) | 1995-06-20 |
| EP0563336A1 (de) | 1993-10-06 |
| EP0563336B1 (de) | 2001-08-22 |
| DE69232016D1 (de) | 2001-09-27 |
| WO1993000083A1 (en) | 1993-01-07 |
| AU2018792A (en) | 1993-01-25 |
| ITMI911791A1 (it) | 1992-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |