IT1248588B - Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. - Google Patents

Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.

Info

Publication number
IT1248588B
IT1248588B ITMI911791A ITMI911791A IT1248588B IT 1248588 B IT1248588 B IT 1248588B IT MI911791 A ITMI911791 A IT MI911791A IT MI911791 A ITMI911791 A IT MI911791A IT 1248588 B IT1248588 B IT 1248588B
Authority
IT
Italy
Prior art keywords
substances
craving
nicotine
dependence
abstinence
Prior art date
Application number
ITMI911791A
Other languages
English (en)
Inventor
Gaetano Crepaldi
Santo Ferrara
Luigi Gallimberti
Gian Luigi Gessa
Original Assignee
Gaetano Crepaldi
Santo Ferrara
Luigi Gallimberti
Gian Luigi Gessa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gaetano Crepaldi, Santo Ferrara, Luigi Gallimberti, Gian Luigi Gessa filed Critical Gaetano Crepaldi
Priority to ITMI911791A priority Critical patent/IT1248588B/it
Publication of ITMI911791A0 publication Critical patent/ITMI911791A0/it
Priority to AU20187/92A priority patent/AU2018792A/en
Priority to PCT/EP1992/001409 priority patent/WO1993000083A1/en
Priority to EP92912485A priority patent/EP0563336B1/en
Priority to DE69232016T priority patent/DE69232016T2/de
Priority to US08/081,388 priority patent/US5426120A/en
Priority to AT92912485T priority patent/ATE204473T1/de
Publication of ITMI911791A1 publication Critical patent/ITMI911791A1/it
Application granted granted Critical
Publication of IT1248588B publication Critical patent/IT1248588B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'acido ?-idrossibutirrico e sue forme fisiologicamente equivalenti sono utili per il trattamento delle sindromi di astinenza del "craving" e della dipendenza da sostanze stupefacenti e/o psicoattive, da nicotina o da distributori alimentari.
ITMI911791A 1991-06-28 1991-06-28 Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. IT1248588B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI911791A IT1248588B (it) 1991-06-28 1991-06-28 Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.
AU20187/92A AU2018792A (en) 1991-06-28 1992-06-23 Pharmaceutical composition containing gamma-hydroxybutyric acid or its lactone in the treatment of drug dependence and nutritional disorders
PCT/EP1992/001409 WO1993000083A1 (en) 1991-06-28 1992-06-23 Pharmaceutical composition containing gamma-hydroxybutyric acid or its lactone in the treatment of drug dependence and nutritional disorders
EP92912485A EP0563336B1 (en) 1991-06-28 1992-06-23 Pharmaceutical composition containing gamma-hydroxybutyric acid or its lactone in the treatment of drug dependence and nutritional disorders
DE69232016T DE69232016T2 (de) 1991-06-28 1992-06-23 Pharmazeutische zusammensetzung, die gamma-hydroxybuttersäure oder das entsprechende lakton enthält, zur behandlung von drogenabhängigkeit und ernährungsstörungen
US08/081,388 US5426120A (en) 1991-06-28 1992-06-23 Pharmaceutical composition containing γ-hydroxybutyric acid or its lactone in the treatment of drug dependence and nutritional disorders
AT92912485T ATE204473T1 (de) 1991-06-28 1992-06-23 Pharmazeutische zusammensetzung, die gamma- hydroxybuttersäure oder das entsprechende lakton enthält, zur behandlung von drogenabhängigkeit und ernährungsstörungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911791A IT1248588B (it) 1991-06-28 1991-06-28 Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.

Publications (3)

Publication Number Publication Date
ITMI911791A0 ITMI911791A0 (it) 1991-06-28
ITMI911791A1 ITMI911791A1 (it) 1992-12-28
IT1248588B true IT1248588B (it) 1995-01-19

Family

ID=11360230

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911791A IT1248588B (it) 1991-06-28 1991-06-28 Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.

Country Status (7)

Country Link
US (1) US5426120A (it)
EP (1) EP0563336B1 (it)
AT (1) ATE204473T1 (it)
AU (1) AU2018792A (it)
DE (1) DE69232016T2 (it)
IT (1) IT1248588B (it)
WO (1) WO1993000083A1 (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234947A (en) * 1991-11-07 1993-08-10 New York University Potassium channel activating compounds and methods of use thereof
IT1266565B1 (it) 1993-07-22 1997-01-09 Ct Lab Farm Srl Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico.
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo
CA2355293C (en) 1998-12-23 2005-08-16 Orphan Medical, Inc. Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
DE60007078T2 (de) * 1999-02-01 2004-12-16 Ortho-Mcneil Pharmaceutical, Inc. Verwendung von antikonvulsiven derivaten zur behandlung von bulimia nervosa
RU2210360C1 (ru) * 2002-09-19 2003-08-20 Общество С Ограниченной Ответственностью "Консорциум-Пик" Психотропное средство
US8193211B2 (en) * 2004-09-30 2012-06-05 Supernus Pharmaceuticals, Inc. Controlled release compositions of gamma-hydroxybutyrate
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
EP2421808B1 (en) 2009-04-23 2013-07-31 Concert Pharmaceuticals Inc. 4-hydroxybutyric acid analogs
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
KR101976218B1 (ko) * 2011-02-14 2019-05-07 콘서트 파마슈티컬즈, 인크. 4-히드록시부티르산 중수소화 유사체
US11000498B2 (en) 2016-07-22 2021-05-11 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US12478604B1 (en) 2016-07-22 2025-11-25 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US12186296B1 (en) 2016-07-22 2025-01-07 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
EP3930702A1 (en) 2019-03-01 2022-01-05 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD139519A1 (de) * 1978-11-10 1980-01-09 Annedore Wehl Verfahren zur herstellung analgetischer formulierungen mit verbesserten gebrauchswerteigenschaften
IT1217783B (it) * 1988-06-03 1990-03-30 Farmaceutico Ct S R L Lab Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative

Also Published As

Publication number Publication date
ITMI911791A0 (it) 1991-06-28
DE69232016T2 (de) 2002-05-29
US5426120A (en) 1995-06-20
ATE204473T1 (de) 2001-09-15
EP0563336A1 (en) 1993-10-06
EP0563336B1 (en) 2001-08-22
DE69232016D1 (de) 2001-09-27
WO1993000083A1 (en) 1993-01-07
AU2018792A (en) 1993-01-25
ITMI911791A1 (it) 1992-12-28

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970626