ATE204603T1 - Klonierung durch komplementierung und verwandte prozesse - Google Patents

Klonierung durch komplementierung und verwandte prozesse

Info

Publication number
ATE204603T1
ATE204603T1 AT95101715T AT95101715T ATE204603T1 AT E204603 T1 ATE204603 T1 AT E204603T1 AT 95101715 T AT95101715 T AT 95101715T AT 95101715 T AT95101715 T AT 95101715T AT E204603 T1 ATE204603 T1 AT E204603T1
Authority
AT
Austria
Prior art keywords
products
proteins
mammalian genes
complement
modify
Prior art date
Application number
AT95101715T
Other languages
English (en)
Inventor
Michael H Wigler
John J Colicelli
Original Assignee
Cold Spring Harbor Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab filed Critical Cold Spring Harbor Lab
Application granted granted Critical
Publication of ATE204603T1 publication Critical patent/ATE204603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Details Of Aerials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT95101715T 1990-04-20 1991-04-19 Klonierung durch komplementierung und verwandte prozesse ATE204603T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/511,715 US6080540A (en) 1990-04-20 1990-04-20 Cloning of mammalian genes in microbial organisms and methods for pharmacological screening

Publications (1)

Publication Number Publication Date
ATE204603T1 true ATE204603T1 (de) 2001-09-15

Family

ID=24036135

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95101715T ATE204603T1 (de) 1990-04-20 1991-04-19 Klonierung durch komplementierung und verwandte prozesse

Country Status (9)

Country Link
US (5) US6080540A (de)
EP (3) EP0940469A3 (de)
JP (3) JP4031027B2 (de)
AT (1) ATE204603T1 (de)
CA (1) CA2080920C (de)
DE (1) DE69132701T2 (de)
DK (1) DK0666314T3 (de)
ES (1) ES2165397T3 (de)
WO (1) WO1991016457A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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US6080540A (en) * 1990-04-20 2000-06-27 Cold Spring Harbor Laboratory Cloning of mammalian genes in microbial organisms and methods for pharmacological screening
US6100025A (en) * 1990-04-20 2000-08-08 Cold Spring Harbor Laboratory Cloning by complementation and related processes
ATE250629T1 (de) * 1991-04-19 2003-10-15 Univ Washington Für säugetierphosphodiesterasen kodierende dns
FR2689905B1 (fr) * 1992-04-13 1995-07-13 Orsan Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes.
EP0752853B1 (de) * 1993-03-10 2005-09-21 Smithkline Beecham Corporation Phosphodiesterase des menschlichen gehirns
US6323041B1 (en) * 1993-06-11 2001-11-27 Pfizer Inc. Screening novel human phosphodiesterase IV isozymes for compounds which modify their enzymatic activity
US5672509A (en) * 1993-08-25 1997-09-30 Pfizer Inc. hPDE IV-C: a human phosphodiesterase IV isozyme
US6069240A (en) * 1994-03-01 2000-05-30 Icos Corporation Cloning by complementation and related processes
US6015880A (en) * 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US6558633B1 (en) 1994-09-21 2003-05-06 Isis Pharmaceuticals, Inc. Chemical reaction apparatus and methods
US5871945A (en) * 1994-11-23 1999-02-16 Icos Corporation Modulators of anchoring protein function
WO1996020281A1 (en) 1994-12-23 1996-07-04 Celltech Therapeutics Limited Human phosphodiesterase type ivc, and its production and use
CA2219136A1 (en) * 1995-04-24 1996-10-31 Chromaxome Corp. Methods for generating and screening novel metabolic pathways
US5795735A (en) * 1995-07-17 1998-08-18 Icos Corporation Isolated polynucleotides encoding PKA-binding proteins and methods of producing the proteins recombinantly
US5783431A (en) * 1996-04-24 1998-07-21 Chromaxome Corporation Methods for generating and screening novel metabolic pathways
US6242211B1 (en) 1996-04-24 2001-06-05 Terragen Discovery, Inc. Methods for generating and screening novel metabolic pathways
US5958342A (en) * 1996-05-17 1999-09-28 Incyte Pharmaceuticals, Inc. Jet droplet device
EP0973899A2 (de) * 1997-04-10 2000-01-26 Genetics Institute, Inc. SEKRETIERTE EXPRIMIERTE SEQUENZMARKER (sESTs)
US5965707A (en) * 1997-09-11 1999-10-12 Beth Israel Deaconess Medical Center Rin2, a novel inhibitor of Ras-mediated signaling
AU9315698A (en) * 1997-09-11 1999-03-29 Beth Israel Deaconess Medical Center (rin2), a novel inhibitor of ras-mediated signaling
US20060009633A9 (en) * 1997-11-13 2006-01-12 Genset, S.A. Complementary DNAs encoding proteins with signal peptides
US6548633B1 (en) 1998-12-22 2003-04-15 Genset, S.A. Complementary DNA's encoding proteins with signal peptides
US20060286639A1 (en) * 1997-11-13 2006-12-21 Serono Genetics Institute S.A. Complementary DNAs encoding proteins with signal peptides
DE19822287C2 (de) * 1998-05-18 2003-04-24 Switch Biotech Ag Klonierungsvektor, seine Herstellung und Verwendung zur Analyse von mRNA Expressionsmuster
US6506889B1 (en) * 1998-05-19 2003-01-14 University Technology Corporation Ras suppressor SUR-8 and related compositions and methods
DK1018559T3 (da) 1998-12-23 2007-12-03 Pfizer Phosphodiesteraser
EP1157007A1 (de) 1999-02-25 2001-11-28 Merck Frosst Canada Inc. Pde-iv hemmende verbindungen, zusammensetzungen und verfahren zur herstellung
US7098015B2 (en) * 1999-06-11 2006-08-29 Millennium Pharmaceuticals, Inc. 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor
US6146876A (en) * 1999-06-11 2000-11-14 Millennium Pharmaceuticals, Inc. 22025, a novel human cyclic nucleotide phosphodiesterase
WO2001055301A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001083772A1 (en) * 2000-04-28 2001-11-08 Merck Patent Gmbh Splice variant of camp phosphodiesterase type 7 (pde7a3)
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
AU784975B2 (en) * 2000-10-11 2006-08-10 Sumitomo Chemical Company, Limited DNA-binding protein YB-1-containing collagen accumulation inhibitors
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
WO2003093296A2 (en) 2002-05-03 2003-11-13 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
WO2004043367A2 (en) * 2002-11-06 2004-05-27 Bristol-Myers Squibb Company Fused heterocyclic compounds and use thereof
AU2003295402A1 (en) * 2002-11-06 2004-06-03 Bristol-Myers Squibb Company Acyl guanidine compounds and use thereof
ATE524556T1 (de) 2005-12-06 2011-09-15 Promega Corp Verfahren zur zyklischen nukleotid-bestimmung
US20100216703A1 (en) * 2006-08-14 2010-08-26 The Regents Of The University Of California Inhibitors of PDE4 and Methods of Use
US9677139B2 (en) 2009-12-11 2017-06-13 Cold Spring Harbor Laboratory Genetic markers indicative of a cancer patient response to trastuzumab (herceptin)
US8993532B2 (en) 2010-04-23 2015-03-31 Cold Spring Harbor Laboratory Structurally designed shRNAs
CA3210003A1 (en) 2010-10-22 2012-04-26 Cold Spring Harbor Laboratory Varietal counting of nucleic acids for obtaining genomic copy number information
US11702627B2 (en) * 2016-02-18 2023-07-18 Tianjin University High cAMP yielding yeast strain and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861709A (en) * 1985-05-31 1989-08-29 Technicon Research A.G. Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker
AU7512287A (en) * 1986-05-20 1987-12-22 Dana-Farber Cancer Institute Expression of human t-cell lymphotropic virus (htlv-iii)reve rse transcriptase and uses thereof
US4980281A (en) * 1988-02-10 1990-12-25 Housey Gerard M Method of screening for protein inhibitors and activators
US6080540A (en) * 1990-04-20 2000-06-27 Cold Spring Harbor Laboratory Cloning of mammalian genes in microbial organisms and methods for pharmacological screening
DK0548165T3 (da) 1990-09-13 2001-07-16 Univ Duke Ekspression af G-proteinkoblede receptorer i gær

Also Published As

Publication number Publication date
JP4031027B2 (ja) 2008-01-09
US6080540A (en) 2000-06-27
US6569617B1 (en) 2003-05-27
EP0940469A3 (de) 1999-12-22
JPH11253200A (ja) 1999-09-21
US5527896A (en) 1996-06-18
JPH11239481A (ja) 1999-09-07
DE69132701D1 (de) 2001-09-27
EP0537173A1 (de) 1993-04-21
EP0666314A1 (de) 1995-08-09
EP0666314B1 (de) 2001-08-22
HK1013314A1 (en) 1999-08-20
EP0940469A2 (de) 1999-09-08
ES2165397T3 (es) 2002-03-16
CA2080920A1 (en) 1991-10-21
DE69132701T2 (de) 2002-06-20
EP0537173A4 (en) 1993-12-22
CA2080920C (en) 2003-07-08
JP3258635B2 (ja) 2002-02-18
US20060199247A1 (en) 2006-09-07
US20040086900A1 (en) 2004-05-06
JPH05507196A (ja) 1993-10-21
DK0666314T3 (da) 2001-12-10
WO1991016457A1 (en) 1991-10-31

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee