ATE206401T1 - Zwischenprodukte für die herstellung von derivaten der 4-oxochinolin-3-carbonsäure - Google Patents

Zwischenprodukte für die herstellung von derivaten der 4-oxochinolin-3-carbonsäure

Info

Publication number
ATE206401T1
ATE206401T1 AT94103669T AT94103669T ATE206401T1 AT E206401 T1 ATE206401 T1 AT E206401T1 AT 94103669 T AT94103669 T AT 94103669T AT 94103669 T AT94103669 T AT 94103669T AT E206401 T1 ATE206401 T1 AT E206401T1
Authority
AT
Austria
Prior art keywords
oxocinoline
derivatives
production
carbonic acid
intermediate products
Prior art date
Application number
AT94103669T
Other languages
English (en)
Inventor
Masayuki Iwata
Tomio Kimura
Teruhiko Inoue
Yoshimi Fujihara
Tetsushi Katsube
Original Assignee
Ube Industries
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries, Sankyo Co filed Critical Ube Industries
Application granted granted Critical
Publication of ATE206401T1 publication Critical patent/ATE206401T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT94103669T 1988-07-20 1989-07-20 Zwischenprodukte für die herstellung von derivaten der 4-oxochinolin-3-carbonsäure ATE206401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18055788 1988-07-20
JP22422088 1988-09-07

Publications (1)

Publication Number Publication Date
ATE206401T1 true ATE206401T1 (de) 2001-10-15

Family

ID=26500036

Family Applications (2)

Application Number Title Priority Date Filing Date
AT89307423T ATE117295T1 (de) 1988-07-20 1989-07-20 4-oxochinolin-3-carbonsäure-derivate, ihre herstellung und ihre verwendung.
AT94103669T ATE206401T1 (de) 1988-07-20 1989-07-20 Zwischenprodukte für die herstellung von derivaten der 4-oxochinolin-3-carbonsäure

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT89307423T ATE117295T1 (de) 1988-07-20 1989-07-20 4-oxochinolin-3-carbonsäure-derivate, ihre herstellung und ihre verwendung.

Country Status (14)

Country Link
US (4) US5348961A (de)
EP (2) EP0610958B1 (de)
KR (2) KR950010325B1 (de)
CN (1) CN1028226C (de)
AT (2) ATE117295T1 (de)
AU (1) AU618823B2 (de)
CA (1) CA1335670C (de)
DE (2) DE68920654T2 (de)
DK (1) DK175617B1 (de)
ES (1) ES2070175T3 (de)
FI (1) FI95130C (de)
GR (1) GR3015818T3 (de)
IE (1) IE68941B1 (de)
NO (1) NO175256C (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE4015299A1 (de) * 1990-05-12 1991-11-14 Bayer Ag Verfahren zur herstellung von 3-amino-2-(het)-aroyl-acrylsaeurederivaten
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
JP3165742B2 (ja) * 1991-07-16 2001-05-14 中外製薬株式会社 キノロンカルボン酸誘導体の製造方法
EP0545866A1 (de) * 1991-12-06 1993-06-09 Ciba-Geigy Ag Verfahren zur Herstellung von Trifluorbenzolderivaten
TW222272B (de) * 1992-05-26 1994-04-11 Ss Seiyaku Kk
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
DE4232505A1 (de) * 1992-09-29 1994-03-31 Degussa Verfahren zur Reduktion von Carbonsäuren oder Carbonsäurederivaten sowie neue Verbindungen
CA2152828A1 (en) * 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
FR2706459B1 (fr) * 1993-06-17 1995-08-04 Bouchara Sa Nouveaux dérivés quinoloniques, leur procédé d'obtention et les compositions pharmaceutiques qui en contiennent.
US6964611B2 (en) * 1996-12-30 2005-11-15 Walker Digital, Llc System and method for automated play of lottery games
ATE423776T1 (de) 1997-09-15 2009-03-15 Procter & Gamble Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
US6387928B1 (en) * 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US6531624B1 (en) 1998-11-18 2003-03-11 Asahi Glass Company Ltd. Aminoacrylic acid derivatives and process for producing the same
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
PT1262477E (pt) * 2000-02-09 2008-11-14 Daiichi Sankyo Co Ltd Agentes anti-bacterianos resistentes a ácidos contendo, como princípio activo, ácidos piridinocarboxílicos
US6878713B2 (en) * 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en) * 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
EP1660495B1 (de) 2003-09-04 2007-07-11 Wockhardt Limited Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat
WO2005026145A2 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
ES2232309B1 (es) * 2003-11-13 2006-08-01 Quimica Sintetica, S.A. Procedimiento simplificado para la obtencion de gatifloxacino.
DE102004035203A1 (de) 2004-07-21 2006-02-16 Bayer Healthcare Ag Substituierte Chinolone
DE102006005861A1 (de) 2006-02-09 2007-08-23 Aicuris Gmbh & Co. Kg Substituierte Chinolone III
ES2284380B1 (es) * 2006-03-10 2008-11-01 Quimica Sintetica S.A. Procedimiento para la preparacion de moxifloxacino y moxifloxacino clorhidrato.
PT2001862E (pt) * 2006-03-28 2011-07-20 Warner Chilcott Co Llc Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico
WO2007110836A1 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
CN100415212C (zh) * 2006-07-21 2008-09-03 哈药集团制药总厂 一种含乳酸卡德沙星的口服制剂
WO2008144536A1 (en) 2007-05-17 2008-11-27 Walker Digital, Llc Group play of lottery game
CN101775005B (zh) * 2009-01-13 2013-12-04 江苏恒瑞医药股份有限公司 盐酸卡屈沙星i型结晶及其制备方法
CN108129404B (zh) * 2018-01-30 2020-05-01 凯瑞斯德生化(苏州)有限公司 手性哌嗪酮衍生物的合成方法
CN108299317A (zh) * 2018-03-20 2018-07-20 爱斯特（成都）生物制药股份有限公司 1,4-二氮杂螺[5,5]十一烷盐酸盐的合成方法
CN108840814B (zh) * 2018-07-24 2021-09-24 南京药石科技股份有限公司 一种8-氧代-2,6,9-三氮杂螺[4.5]癸烷-2-羧酸叔丁酯制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
AU618235B2 (en) * 1986-03-31 1991-12-19 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US4803205A (en) * 1987-08-07 1989-02-07 Warner-Lambert Company Quinolones as antibacterial agents
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Also Published As

Publication number Publication date
IE892340L (en) 1990-01-20
EP0352123A2 (de) 1990-01-24
ATE117295T1 (de) 1995-02-15
EP0610958A3 (de) 1995-03-22
ES2070175T3 (es) 1995-06-01
FI95130B (fi) 1995-09-15
NO892952D0 (no) 1989-07-19
AU3821889A (en) 1990-01-25
EP0352123B1 (de) 1995-01-18
US5348961A (en) 1994-09-20
DE68929330D1 (de) 2001-11-08
EP0610958B1 (de) 2001-10-04
FI893467L (fi) 1990-01-21
US5496951A (en) 1996-03-05
FI95130C (fi) 1995-12-27
CA1335670C (en) 1995-05-23
NO892952L (no) 1990-01-22
CN1040977A (zh) 1990-04-04
FI893467A0 (fi) 1989-07-18
NO175256C (no) 1994-09-21
US5436367A (en) 1995-07-25
DK175617B1 (da) 2004-12-27
EP0610958A2 (de) 1994-08-17
AU618823B2 (en) 1992-01-09
NO175256B (no) 1994-06-13
KR900001686A (ko) 1990-02-27
IE68941B1 (en) 1996-07-24
DK359289D0 (da) 1989-07-19
GR3015818T3 (en) 1995-07-31
DE68929330T2 (de) 2002-07-04
US5073556A (en) 1991-12-17
DE68920654D1 (de) 1995-03-02
KR950010325B1 (ko) 1995-09-14
CN1028226C (zh) 1995-04-19
DK359289A (da) 1990-01-21
EP0352123A3 (en) 1990-09-05
DE68920654T2 (de) 1995-08-31
KR950011396B1 (ko) 1995-10-02

Similar Documents

Publication Publication Date Title
ATE206401T1 (de) Zwischenprodukte für die herstellung von derivaten der 4-oxochinolin-3-carbonsäure
SE8200815L (sv) Kemisk forening till anvendning som mellanprodukt vid framstellning av vissa triazolforeningar
ATE183993T1 (de) Zwischenprodukte für die herstellung einer substituierten 2,5-diamino-3-hydroxyhexan.
ATE57699T1 (de) Pyridoncarbonsauere-derivate und verfahren zu ihrer herstellung.
DE69109514D1 (de) 4-(4-Alkoxyphenyl)-2-Butylaminderivate und deren Herstellungsverfahren.
HUT45984A (en) Process for production of quinoline-derivatives and of their medically acceptable acid-additioned salts
ATE45354T1 (de) Chinoloncarbonsaeurederivate.
EP0228845A3 (en) N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same
DE3882895D1 (de) Imid-derivate, ihre herstellung und verwendung.
DE3864707D1 (de) Benzoxazin-derivate und verfahren zu ihrer herstellung.
ATE137747T1 (de) Aminobenzolverbindungen, herstellung und verwendung
DE3772235D1 (de) Thianaphthen-derivate, ihre herstellung und verwendung.
GR3003126T3 (en) Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments
EP0555479A4 (de)
ATE52509T1 (de) Thiazolidinderivate und verfahren zu ihrer herstellung.
EP0309261A3 (en) Butenoic acid amides, their salts, pharmaceutical compositions containing them and process for preparing same
DE3679257D1 (de) 4-cyanopiperidine-derivate, herstellung und anwendung.
ATE198194T1 (de) Azetidinonderivate für die herstellung von carbapenemantibiotika
ATE44741T1 (de) 2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.
HUT39173A (en) Process for production of derivatives of 3-hydro-amino-2,3-dihydro-benzoxepin
MY105537A (en) Preparation process of new thieno-triazolo- diazepine.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee