ATE206457T1 - Rekombinanter gen kodierend für alpha interferon und expressionsvector dafür - Google Patents
Rekombinanter gen kodierend für alpha interferon und expressionsvector dafürInfo
- Publication number
- ATE206457T1 ATE206457T1 AT92122084T AT92122084T ATE206457T1 AT E206457 T1 ATE206457 T1 AT E206457T1 AT 92122084 T AT92122084 T AT 92122084T AT 92122084 T AT92122084 T AT 92122084T AT E206457 T1 ATE206457 T1 AT E206457T1
- Authority
- AT
- Austria
- Prior art keywords
- expression vector
- alpha interferon
- gene coding
- recombinant gene
- coding alpha
- Prior art date
Links
- 102000006992 Interferon-alpha Human genes 0.000 title abstract 2
- 108010047761 Interferon-alpha Proteins 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 210000005253 yeast cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019910025878A KR930008976B1 (ko) | 1991-12-31 | 1991-12-31 | 인간 알파인터페론 유전자의 발현벡터 |
| KR1019910025879A KR940001308B1 (ko) | 1991-12-31 | 1991-12-31 | 인간 알파 인터페론 유전자 및 발현벡터 |
| KR1019920001155A KR950004014B1 (ko) | 1992-01-28 | 1992-01-28 | 재조합 알파 인터페론의 개선된 정제 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206457T1 true ATE206457T1 (de) | 2001-10-15 |
Family
ID=27348802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92122084T ATE206457T1 (de) | 1991-12-31 | 1992-12-29 | Rekombinanter gen kodierend für alpha interferon und expressionsvector dafür |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP0553494B1 (de) |
| CN (1) | CN1062014C (de) |
| AT (1) | ATE206457T1 (de) |
| AU (1) | AU648214B2 (de) |
| ES (1) | ES2165352T3 (de) |
| TW (1) | TW242653B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0679718T3 (da) * | 1994-04-09 | 2001-10-22 | Hoffmann La Roche | Fremgangsmåde til fremstilling af alfa-interferon |
| CA2285676C (en) | 1997-04-04 | 2011-03-08 | Donald P. Weeks | Methods and materials for making and using transgenic dicamba-degrading organisms |
| US7105724B2 (en) | 1997-04-04 | 2006-09-12 | Board Of Regents Of University Of Nebraska | Methods and materials for making and using transgenic dicamba-degrading organisms |
| DE19748734A1 (de) * | 1997-11-05 | 1999-05-06 | Biotechnolog Forschung Gmbh | Verfahren zur Gewinnung von biologisch aktiven Dimeren von rekombinanten humanen Wachstumsfaktoren aus der Cystein-Knoten-Familie sowie Verwendung der gewonnenen Dimere |
| CN101255188A (zh) * | 1998-11-12 | 2008-09-03 | 先灵公司 | 干扰素同种型的转化方法及其产物 |
| CN1113964C (zh) * | 1999-05-25 | 2003-07-09 | 上海华新生物高技术有限公司 | 人工合成的干扰素α-2b基因在大肠杆菌中的高效表达 |
| WO2002031178A1 (en) * | 2000-10-12 | 2002-04-18 | Uab Research Foundation | An artificial gene and vectors for expressing high-yield recombinant ovine interferon-tau in pichia pastoris |
| JP2005505494A (ja) * | 2001-02-23 | 2005-02-24 | イミュネックス・コーポレーション | 活性タンパク質の回収増加 |
| FR2823220B1 (fr) | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| RU2238758C2 (ru) * | 2002-07-24 | 2004-10-27 | Закрытое акционерное общество "Вектор-Медика" | Водный раствор интерферона-альфа-два человека для инъекций |
| JP5553963B2 (ja) | 2004-10-22 | 2014-07-23 | アムジエン・インコーポレーテツド | 組換え抗体をリフォールディングする方法 |
| CN1746306B (zh) * | 2005-08-02 | 2010-08-25 | 成都地奥制药集团有限公司 | 一种重组人干扰素α4编码cDNA序列及其制备方法和应用 |
| US7855326B2 (en) | 2006-06-06 | 2010-12-21 | Monsanto Technology Llc | Methods for weed control using plants having dicamba-degrading enzymatic activity |
| AR063316A1 (es) | 2006-10-16 | 2009-01-21 | Monsanto Technology Llc | Metodos y composiciones para mejorar el estado sanitario de plantas |
| US7838729B2 (en) | 2007-02-26 | 2010-11-23 | Monsanto Technology Llc | Chloroplast transit peptides for efficient targeting of DMO and uses thereof |
| CN101818154B (zh) * | 2010-03-26 | 2012-12-26 | 华南农业大学 | 编码猪α干扰素的基因片段及其应用 |
| CN108911323B (zh) * | 2018-06-27 | 2021-04-23 | 湖北远大生物技术有限公司 | 一种酶促反应l-胱氨酸母液的再利用工艺 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2125047B (en) * | 1982-08-09 | 1986-02-19 | Ciba Geigy Ag | Yeast hybrid vectors and their use for the production of polypeptides |
| ZA844082B (en) * | 1983-06-01 | 1985-09-25 | Hoffmann La Roche | Polypeptides having interferon activity |
| JPS6079000A (ja) * | 1983-10-04 | 1985-05-04 | Takeda Chem Ind Ltd | ヒトγ型インタ−フエロン単量体の製造法 |
| US4569790A (en) * | 1984-03-28 | 1986-02-11 | Cetus Corporation | Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions |
| DE3511011A1 (de) * | 1985-03-27 | 1986-10-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur isolierung und reinigung von (alpha)-interferonen |
| US4751078A (en) * | 1985-07-03 | 1988-06-14 | Nagabhushan Tattanahalli L | Process for the purification of gamma interferon |
| CA1340586C (en) * | 1988-09-23 | 1999-06-08 | Cetus Corporation | Process for recovering microbially produced interferon-beta |
| JPH02145193A (ja) * | 1988-11-19 | 1990-06-04 | Lotte Confectionery Co Ltd | 遺伝子の組換えによる酵母でのヒト・アルファ・インターフェロンの製造方法 |
-
1992
- 1992-12-22 AU AU30371/92A patent/AU648214B2/en not_active Expired
- 1992-12-29 EP EP92122084A patent/EP0553494B1/de not_active Expired - Lifetime
- 1992-12-29 EP EP01101958A patent/EP1097995A1/de not_active Withdrawn
- 1992-12-29 AT AT92122084T patent/ATE206457T1/de active
- 1992-12-29 ES ES92122084T patent/ES2165352T3/es not_active Expired - Lifetime
- 1992-12-31 CN CN92111826A patent/CN1062014C/zh not_active Expired - Lifetime
-
1993
- 1993-01-19 TW TW082100318A patent/TW242653B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW242653B (de) | 1995-03-11 |
| EP0553494A1 (de) | 1993-08-04 |
| AU3037192A (en) | 1993-07-08 |
| EP0553494B1 (de) | 2001-10-04 |
| EP1097995A1 (de) | 2001-05-09 |
| CN1073977A (zh) | 1993-07-07 |
| ES2165352T3 (es) | 2002-03-16 |
| AU648214B2 (en) | 1994-04-14 |
| CN1062014C (zh) | 2001-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |