ATE207343T1 - O-carboxymethylchitosan enthaltende mittel und ihre verwendung in ophthalmika - Google Patents
O-carboxymethylchitosan enthaltende mittel und ihre verwendung in ophthalmikaInfo
- Publication number
- ATE207343T1 ATE207343T1 AT96928418T AT96928418T ATE207343T1 AT E207343 T1 ATE207343 T1 AT E207343T1 AT 96928418 T AT96928418 T AT 96928418T AT 96928418 T AT96928418 T AT 96928418T AT E207343 T1 ATE207343 T1 AT E207343T1
- Authority
- AT
- Austria
- Prior art keywords
- polysaccharide
- solution
- carboxymethylchitosan
- ophthalmics
- agents containing
- Prior art date
Links
- 150000004676 glycans Chemical class 0.000 abstract 4
- 229920001282 polysaccharide Polymers 0.000 abstract 4
- 239000005017 polysaccharide Substances 0.000 abstract 4
- 229920001661 Chitosan Polymers 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000001954 sterilising effect Effects 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 229920002101 Chitin Polymers 0.000 abstract 1
- 230000000593 degrading effect Effects 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51642095A | 1995-08-17 | 1995-08-17 | |
| PCT/EP1996/003477 WO1997006782A1 (en) | 1995-08-17 | 1996-08-06 | Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE207343T1 true ATE207343T1 (de) | 2001-11-15 |
Family
ID=24055505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96928418T ATE207343T1 (de) | 1995-08-17 | 1996-08-06 | O-carboxymethylchitosan enthaltende mittel und ihre verwendung in ophthalmika |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5773608A (de) |
| EP (1) | EP0844868B1 (de) |
| JP (1) | JPH11510497A (de) |
| AT (1) | ATE207343T1 (de) |
| AU (1) | AU6789796A (de) |
| DE (1) | DE69616347T2 (de) |
| DK (1) | DK0844868T3 (de) |
| ES (1) | ES2166905T3 (de) |
| PT (1) | PT844868E (de) |
| TW (1) | TW389694B (de) |
| WO (1) | WO1997006782A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19617019A1 (de) | 1996-04-27 | 1997-11-06 | Beiersdorf Ag | Alkyl-2-acetamino-2-desoxy-glucopyranosid-uronsäuren und -Derivate, ihre Herstellung sowie ihre Verwendung als Tenside in kosmetischen und pharmazeutischen Zubereitungen |
| DK0893121T3 (da) * | 1997-06-27 | 2002-06-17 | Akzo Nobel Nv | Flydende oral medicinopløsning |
| CA2212300A1 (en) * | 1997-08-04 | 1999-02-04 | Abdellatif Chenite | In vitro or in vivo gelfying chitosan and therapeutic uses thereof |
| BR9912627A (pt) | 1998-07-30 | 2002-02-13 | Nutriceuticals Inc E | Composição em suspensão lìquida estável, e, processos para preparação e uso da mesma e para tratamento de peso e de colesterol |
| WO2001000044A1 (en) * | 1999-06-25 | 2001-01-04 | E-Nutriceuticals, Inc. | Novel chitosan-containing liquid compositions and methods for their preparation and use |
| US6537584B1 (en) * | 1999-11-12 | 2003-03-25 | Macromed, Inc. | Polymer blends that swell in an acidic environment and deswell in a basic environment |
| EP1240230B1 (de) * | 1999-11-12 | 2006-03-01 | MacroMed, Inc. | An- und abschwellende polymermischungen |
| DK1229940T3 (da) * | 1999-11-15 | 2014-08-18 | Piramal Healthcare Canada Ltd | Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning |
| ATE243049T1 (de) * | 1999-12-09 | 2003-07-15 | Biosyntech Canada Inc | Mineral-polymer hybrid-zusammensetzung |
| US20030158302A1 (en) * | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
| US6716970B2 (en) | 2000-04-21 | 2004-04-06 | Adjuvant Pharmaceuticals, Llc | Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof |
| IL153490A0 (en) * | 2000-06-29 | 2003-07-06 | Biosyntech Canada Inc | Composition and method for the repair and regeneration of cartilage and other tissues |
| AU2001288120A1 (en) * | 2000-09-26 | 2002-04-08 | Kyorin Pharmaceutical Co. Ltd. | Liquid prednisolone sodium phosphate preparation |
| WO2002040070A2 (en) * | 2000-11-15 | 2002-05-23 | Bio Syntech Canada Inc. | Method for restoring a damaged or degenerated intervertebral disc |
| US6756363B1 (en) * | 2000-11-17 | 2004-06-29 | Wound Healing Of Oklahoma, Inc. | Solutions and films of glycated chitosan |
| AR034372A1 (es) * | 2001-06-08 | 2004-02-18 | Novartis Ag | Composiciones farmaceuticas |
| ATE481110T1 (de) * | 2002-07-16 | 2010-10-15 | Biosyntech Canada Inc | Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren |
| US6896809B2 (en) * | 2002-12-20 | 2005-05-24 | Providence Health System - Oregon | Methods for purifying chitosan |
| US7125967B2 (en) | 2003-10-08 | 2006-10-24 | Adjuvant Pharmaceuticals, Llc | Water-soluble chitosan having low endotoxin concentration and methods for making and using the same |
| EP1727525A4 (de) * | 2004-03-23 | 2009-12-09 | Lytone Enterprise Inc | In chitosan eingebettete oder verkapselte kapsel |
| EP1787643A1 (de) * | 2004-09-09 | 2007-05-23 | Jimenez Bayardo, Arturo | Implantat und mikrokugeln zur dauerhaften abgabe von medikamenten zur ophthalmischen anwendung und herstellungsverfahren dafür |
| ATE533491T1 (de) * | 2004-09-21 | 2011-12-15 | Trobio Ab | Stabilisierte protease zusammensetzungen enthaltend eine serinprotease, morpholin-derivate und reversible serinprotease- inhibitoren |
| EP1945712A4 (de) * | 2005-11-04 | 2013-05-01 | Piramal Healthcare Canada Ltd | Gelbindung von wässrigen polyelektrolytlösungen durch thermisch induzierte änderungen des ionisationszustands |
| CN100572388C (zh) * | 2005-12-14 | 2009-12-23 | 河南省科学院河南省发展计划委员会地理研究所 | 乙酰水杨酸与壳聚糖-2,6位接枝物制备方法 |
| PL1978925T3 (pl) * | 2005-12-23 | 2010-01-29 | Laboratoire Medidom S A | Termoutwardzalna zobojętniona kompozycja chitozanu tworząca hydrożel, liofilizat i sposoby ich wytwarzania |
| BRPI0807065A2 (pt) * | 2007-01-31 | 2017-03-21 | Allergan Inc | biomateriais novos para liberação de fármaco ocular e um método para fazer e usar os mesmos |
| KR20180123727A (ko) * | 2012-01-20 | 2018-11-19 | 임무노포토닉스 인코퍼레이티드 | 키토산 유래 조성물 |
| US11773188B2 (en) | 2012-01-20 | 2023-10-03 | Immunophotonics, Inc | Chitosan-derived compositions |
| US20190002594A1 (en) | 2014-07-16 | 2019-01-03 | Immunophotonics, Inc. | Chitosan-Derived Compositions |
| CA3019436A1 (en) | 2016-03-30 | 2017-10-05 | Qualizyme Diagnostics Gmbh & Co Kg | Detecting microbial infection in wounds |
| PT3500255T (pt) * | 2016-08-19 | 2023-01-10 | Orasis Pharmaceuticals Ltd | Composições farmacêuticas oftálmicas e utilizações relacionadas com estas |
| CN109260145B (zh) * | 2018-10-09 | 2020-12-22 | 湖北远大天天明制药有限公司 | 含有珍珠层粉可舒缓眼部疲劳的滴眼液组合物、制备方法与用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386151A (en) * | 1981-06-26 | 1983-05-31 | Polaroid Corporation | Diffusion transfer film system with protective layer of copper salt, chitosan and selected polyols |
| DE3440444A1 (de) * | 1984-11-06 | 1986-05-07 | Dechema Deutsche Gesellschaft für chemisches Apparatewesen e.V., 6000 Frankfurt | Verfahren zur herstellung grob gekoernter schichtsilikate und deren verwendung als adsorbentien fuer proteine |
| GB8520085D0 (en) * | 1985-08-09 | 1985-09-18 | British Food Mfg Ind Res | Foamed food products |
| US4946870A (en) * | 1986-06-06 | 1990-08-07 | Union Carbide Chemicals And Plastics Company Inc. | Delivery systems for pharmaceutical or therapeutic actives |
| IT1190347B (it) * | 1986-06-16 | 1988-02-16 | Franco Conti | Processo per la preparazione dell'n-dimetilchitosano e suoi impieghi farmacologici |
| IT1219942B (it) * | 1988-05-13 | 1990-05-24 | Fidia Farmaceutici | Esteri polisaccaridici |
| US4956350A (en) * | 1988-08-18 | 1990-09-11 | Minnesota Mining And Manufacturing Company | Wound filling compositions |
| US5550187A (en) * | 1988-11-21 | 1996-08-27 | Collagen Corporation | Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
| DE69015775T2 (de) * | 1989-10-31 | 1995-05-11 | Howmedica | Chitinderivate enthaltende Zusammensetzungen zur Verhütung der Adhäsion. |
| US5204452A (en) * | 1990-11-14 | 1993-04-20 | E. I. Du Pont De Nemours And Company | N-halochitosans, their preparation and uses |
| US5212162A (en) * | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| CA2074424A1 (en) * | 1992-07-22 | 1994-01-23 | Bryce L. Fanning | Acoustic gel |
| WO1994007999A1 (en) * | 1992-09-28 | 1994-04-14 | Brown University Research Foundation | Chitosan matrices for encapsulated cells |
| US5420197A (en) * | 1994-01-13 | 1995-05-30 | Hydromer, Inc. | Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives |
| EP0665022A1 (de) * | 1994-01-28 | 1995-08-02 | Prodex, Inc. | Viskoelastische Lösung aus N,O-Carboxymethylchitosan zur opthalmischen Verwendung |
| US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
-
1995
- 1995-12-27 TW TW084113923A patent/TW389694B/zh active
-
1996
- 1996-07-03 US US08/675,748 patent/US5773608A/en not_active Expired - Fee Related
- 1996-08-06 AU AU67897/96A patent/AU6789796A/en not_active Abandoned
- 1996-08-06 WO PCT/EP1996/003477 patent/WO1997006782A1/en not_active Ceased
- 1996-08-06 EP EP96928418A patent/EP0844868B1/de not_active Expired - Lifetime
- 1996-08-06 PT PT96928418T patent/PT844868E/pt unknown
- 1996-08-06 DK DK96928418T patent/DK0844868T3/da active
- 1996-08-06 DE DE69616347T patent/DE69616347T2/de not_active Expired - Fee Related
- 1996-08-06 ES ES96928418T patent/ES2166905T3/es not_active Expired - Lifetime
- 1996-08-06 AT AT96928418T patent/ATE207343T1/de not_active IP Right Cessation
- 1996-08-06 JP JP9507926A patent/JPH11510497A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69616347D1 (de) | 2001-11-29 |
| WO1997006782A1 (en) | 1997-02-27 |
| DK0844868T3 (da) | 2002-01-28 |
| US5773608A (en) | 1998-06-30 |
| PT844868E (pt) | 2002-03-28 |
| EP0844868A1 (de) | 1998-06-03 |
| AU6789796A (en) | 1997-03-12 |
| ES2166905T3 (es) | 2002-05-01 |
| JPH11510497A (ja) | 1999-09-14 |
| EP0844868B1 (de) | 2001-10-24 |
| DE69616347T2 (de) | 2002-07-04 |
| TW389694B (en) | 2000-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |