DK0844868T3 - O-carboxymethylchitosan-holdige midler og deres anvendelse i ophthalmika - Google Patents

O-carboxymethylchitosan-holdige midler og deres anvendelse i ophthalmika

Info

Publication number
DK0844868T3
DK0844868T3 DK96928418T DK96928418T DK0844868T3 DK 0844868 T3 DK0844868 T3 DK 0844868T3 DK 96928418 T DK96928418 T DK 96928418T DK 96928418 T DK96928418 T DK 96928418T DK 0844868 T3 DK0844868 T3 DK 0844868T3
Authority
DK
Denmark
Prior art keywords
polysaccharide
solution
carboxymethylchitosan
ophthalmics
sterilizing
Prior art date
Application number
DK96928418T
Other languages
English (en)
Inventor
Shau-Fong Yen
Kenneth W Reed
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0844868T3 publication Critical patent/DK0844868T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96928418T 1995-08-17 1996-08-06 O-carboxymethylchitosan-holdige midler og deres anvendelse i ophthalmika DK0844868T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51642095A 1995-08-17 1995-08-17
PCT/EP1996/003477 WO1997006782A1 (en) 1995-08-17 1996-08-06 Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics

Publications (1)

Publication Number Publication Date
DK0844868T3 true DK0844868T3 (da) 2002-01-28

Family

ID=24055505

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96928418T DK0844868T3 (da) 1995-08-17 1996-08-06 O-carboxymethylchitosan-holdige midler og deres anvendelse i ophthalmika

Country Status (11)

Country Link
US (1) US5773608A (da)
EP (1) EP0844868B1 (da)
JP (1) JPH11510497A (da)
AT (1) ATE207343T1 (da)
AU (1) AU6789796A (da)
DE (1) DE69616347T2 (da)
DK (1) DK0844868T3 (da)
ES (1) ES2166905T3 (da)
PT (1) PT844868E (da)
TW (1) TW389694B (da)
WO (1) WO1997006782A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19617019A1 (de) 1996-04-27 1997-11-06 Beiersdorf Ag Alkyl-2-acetamino-2-desoxy-glucopyranosid-uronsäuren und -Derivate, ihre Herstellung sowie ihre Verwendung als Tenside in kosmetischen und pharmazeutischen Zubereitungen
DK0893121T3 (da) * 1997-06-27 2002-06-17 Akzo Nobel Nv Flydende oral medicinopløsning
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
BR9912627A (pt) 1998-07-30 2002-02-13 Nutriceuticals Inc E Composição em suspensão lìquida estável, e, processos para preparação e uso da mesma e para tratamento de peso e de colesterol
WO2001000044A1 (en) * 1999-06-25 2001-01-04 E-Nutriceuticals, Inc. Novel chitosan-containing liquid compositions and methods for their preparation and use
US6537584B1 (en) * 1999-11-12 2003-03-25 Macromed, Inc. Polymer blends that swell in an acidic environment and deswell in a basic environment
EP1240230B1 (en) * 1999-11-12 2006-03-01 MacroMed, Inc. Swelling and deswelling polymer blends
DK1229940T3 (da) * 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning
ATE243049T1 (de) * 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
US6716970B2 (en) 2000-04-21 2004-04-06 Adjuvant Pharmaceuticals, Llc Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof
IL153490A0 (en) * 2000-06-29 2003-07-06 Biosyntech Canada Inc Composition and method for the repair and regeneration of cartilage and other tissues
AU2001288120A1 (en) * 2000-09-26 2002-04-08 Kyorin Pharmaceutical Co. Ltd. Liquid prednisolone sodium phosphate preparation
WO2002040070A2 (en) * 2000-11-15 2002-05-23 Bio Syntech Canada Inc. Method for restoring a damaged or degenerated intervertebral disc
US6756363B1 (en) * 2000-11-17 2004-06-29 Wound Healing Of Oklahoma, Inc. Solutions and films of glycated chitosan
AR034372A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
ATE481110T1 (de) * 2002-07-16 2010-10-15 Biosyntech Canada Inc Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren
US6896809B2 (en) * 2002-12-20 2005-05-24 Providence Health System - Oregon Methods for purifying chitosan
US7125967B2 (en) 2003-10-08 2006-10-24 Adjuvant Pharmaceuticals, Llc Water-soluble chitosan having low endotoxin concentration and methods for making and using the same
EP1727525A4 (en) * 2004-03-23 2009-12-09 Lytone Enterprise Inc CAPSULE CONTAINING CHITOSANE NOYE OR ENCAPSULE
EP1787643A1 (en) * 2004-09-09 2007-05-23 Jimenez Bayardo, Arturo Implants and microspheres for the sustained release of drugs for ophthalmic use and preparation methods thereof
ATE533491T1 (de) * 2004-09-21 2011-12-15 Trobio Ab Stabilisierte protease zusammensetzungen enthaltend eine serinprotease, morpholin-derivate und reversible serinprotease- inhibitoren
EP1945712A4 (en) * 2005-11-04 2013-05-01 Piramal Healthcare Canada Ltd BINDING OF AQUEOUS POLYELECTROLYTE SOLUTIONS BY THERMALLY INDUCED CHANGES IN THE IONIZATION CONDITION
CN100572388C (zh) * 2005-12-14 2009-12-23 河南省科学院河南省发展计划委员会地理研究所 乙酰水杨酸与壳聚糖-2，6位接枝物制备方法
PL1978925T3 (pl) * 2005-12-23 2010-01-29 Laboratoire Medidom S A Termoutwardzalna zobojętniona kompozycja chitozanu tworząca hydrożel, liofilizat i sposoby ich wytwarzania
BRPI0807065A2 (pt) * 2007-01-31 2017-03-21 Allergan Inc biomateriais novos para liberação de fármaco ocular e um método para fazer e usar os mesmos
KR20180123727A (ko) * 2012-01-20 2018-11-19 임무노포토닉스 인코퍼레이티드 키토산 유래 조성물
US11773188B2 (en) 2012-01-20 2023-10-03 Immunophotonics, Inc Chitosan-derived compositions
US20190002594A1 (en) 2014-07-16 2019-01-03 Immunophotonics, Inc. Chitosan-Derived Compositions
CA3019436A1 (en) 2016-03-30 2017-10-05 Qualizyme Diagnostics Gmbh & Co Kg Detecting microbial infection in wounds
PT3500255T (pt) * 2016-08-19 2023-01-10 Orasis Pharmaceuticals Ltd Composições farmacêuticas oftálmicas e utilizações relacionadas com estas
CN109260145B (zh) * 2018-10-09 2020-12-22 湖北远大天天明制药有限公司 含有珍珠层粉可舒缓眼部疲劳的滴眼液组合物、制备方法与用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386151A (en) * 1981-06-26 1983-05-31 Polaroid Corporation Diffusion transfer film system with protective layer of copper salt, chitosan and selected polyols
DE3440444A1 (de) * 1984-11-06 1986-05-07 Dechema Deutsche Gesellschaft für chemisches Apparatewesen e.V., 6000 Frankfurt Verfahren zur herstellung grob gekoernter schichtsilikate und deren verwendung als adsorbentien fuer proteine
GB8520085D0 (en) * 1985-08-09 1985-09-18 British Food Mfg Ind Res Foamed food products
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
IT1190347B (it) * 1986-06-16 1988-02-16 Franco Conti Processo per la preparazione dell'n-dimetilchitosano e suoi impieghi farmacologici
IT1219942B (it) * 1988-05-13 1990-05-24 Fidia Farmaceutici Esteri polisaccaridici
US4956350A (en) * 1988-08-18 1990-09-11 Minnesota Mining And Manufacturing Company Wound filling compositions
US5550187A (en) * 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
DE69015775T2 (de) * 1989-10-31 1995-05-11 Howmedica Chitinderivate enthaltende Zusammensetzungen zur Verhütung der Adhäsion.
US5204452A (en) * 1990-11-14 1993-04-20 E. I. Du Pont De Nemours And Company N-halochitosans, their preparation and uses
US5212162A (en) * 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
CA2074424A1 (en) * 1992-07-22 1994-01-23 Bryce L. Fanning Acoustic gel
WO1994007999A1 (en) * 1992-09-28 1994-04-14 Brown University Research Foundation Chitosan matrices for encapsulated cells
US5420197A (en) * 1994-01-13 1995-05-30 Hydromer, Inc. Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
EP0665022A1 (en) * 1994-01-28 1995-08-02 Prodex, Inc. Viscoelastic solution of N,O-carboxymethyl chitosan for ophthalmic use
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system

Also Published As

Publication number Publication date
DE69616347D1 (de) 2001-11-29
WO1997006782A1 (en) 1997-02-27
US5773608A (en) 1998-06-30
PT844868E (pt) 2002-03-28
EP0844868A1 (en) 1998-06-03
AU6789796A (en) 1997-03-12
ES2166905T3 (es) 2002-05-01
JPH11510497A (ja) 1999-09-14
EP0844868B1 (en) 2001-10-24
ATE207343T1 (de) 2001-11-15
DE69616347T2 (de) 2002-07-04
TW389694B (en) 2000-05-11

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