ATE207498T1 - Neutrophilen inhibitoren aus nematoden - Google Patents

Neutrophilen inhibitoren aus nematoden

Info

Publication number: ATE207498T1
Authority: AT; Austria
Prior art keywords: nematodes; compositions; neutrophil; neutrophil inhibitors; inhibitors
Prior art date: 1992-05-11

Application number

AT93911273T

Other languages

English (en)

Inventor

Matthew Moyle

David Lee Foster

George Phillip Vlasuk

Original Assignee

Corvas Int Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-11

Filing date

1993-05-11

Publication date

2001-11-15

1993-05-11 Application filed by Corvas Int Inc filed Critical Corvas Int Inc

2001-11-15 Application granted granted Critical

2001-11-15 Publication of ATE207498T1 publication Critical patent/ATE207498T1/de

Links

210000000440 neutrophil Anatomy 0.000 title abstract 3
241000244206 Nematoda Species 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
102000003886 Glycoproteins Human genes 0.000 abstract 1
108090000288 Glycoproteins Proteins 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000028709 inflammatory response Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
210000003556 vascular endothelial cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
- C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Tropical Medicine & Parasitology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT93911273T 1992-05-11 1993-05-11 Neutrophilen inhibitoren aus nematoden ATE207498T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US88172192A	1992-05-11	1992-05-11
US99697292A	1992-12-24	1992-12-24
PCT/US1993/004502 WO1993023063A1 (en)	1992-05-11	1993-05-11	Novel neutrophil inhibitors

Publications (1)

Publication Number	Publication Date
ATE207498T1 true ATE207498T1 (de)	2001-11-15

Family

ID=27128632

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93911273T ATE207498T1 (de)	1992-05-11	1993-05-11	Neutrophilen inhibitoren aus nematoden

Country Status (13)

Country	Link
US (1)	US6756211B1 (de)
EP (1)	EP0731709B1 (de)
JP (1)	JP3509860B2 (de)
AT (1)	ATE207498T1 (de)
AU (1)	AU687737B2 (de)
CA (1)	CA2135390A1 (de)
DE (1)	DE69331018T2 (de)
DK (1)	DK0731709T3 (de)
ES (1)	ES2168095T3 (de)
MX (1)	MX9302750A (de)
NZ (3)	NZ252591A (de)
PT (1)	PT731709E (de)
WO (1)	WO1993023063A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1749534B1 (de)	1997-12-31	2013-08-21	University Of Iowa Research Foundation	Verwendung von parasitären biologischen Wirkstoffen zur Vorbeugung und Kontrolle von chronisch-entzündlichen Darmerkrankungen
EP1186303A3 (de) *	2000-09-06	2003-12-10	Pfizer Products Inc.	Ein Neutrophilhemmender Faktor und ein selektive NMDA-NR2B Rezeptor Antagonisten enthaltende Kombinationspräparate zur Behandlung von Schlaganfällen und traumatischen Gehirnschäden
WO2006062776A2 (en) *	2004-11-29	2006-06-15	The Regents Of The University Of California	Hydroxyapatite-binding peptides for bone growth and inhibition
DE102007021199B4 (de) *	2006-07-17	2016-02-11	Evonik Degussa Gmbh	Zusammensetzungen aus organischem Polymer als Matrix und anorganischen Partikeln als Füllstoff, Verfahren zu deren Herstellung sowie deren Verwendung und damit hergestellte Formkörper
CA2866819C (en)	2012-03-13	2022-01-04	James Cook University	Method for treating inflammation
JP2016532456A (ja)	2013-09-18	2016-10-20	ジェームス・クック・ユニバーシティー	改変型抗炎症性タンパク質及び使用方法
EP3554257B1 (de)	2016-12-15	2023-07-12	Société des Produits Nestlé S.A.	Zusammensetzungen und verfahren zur modulation von weissen blutkörperchen oder neutrophilen in einem haustier

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4431739A (en) *	1979-11-05	1984-02-14	Genentech, Inc.	Transformant bacterial culture capable of expressing heterologous protein
US4438032A (en) *	1981-01-30	1984-03-20	The Regents Of The University Of California	Unique T-lymphocyte line and products derived therefrom
US5019648A (en) *	1987-07-06	1991-05-28	Dana-Farber Cancer Institute	Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein
DE68923107T2 (de) *	1988-02-26	1996-01-18	Biogen Inc	DNA-Sequenzen, rekombinante DNA-Moleküle und Verfahren zur Herstellung von Lipocortin III, IV, V, und VI.
US5256642A (en) *	1988-04-01	1993-10-26	The Johns Hopkins University	Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
JPH05504470A (ja) *	1989-10-20	1993-07-15	ニューイングランド・メディカル・センター・ホスピタルズ・インコーポレーテッド	Ｐａｄｇｅｍを介した細胞結合の阻害
US5314992A (en) *	1991-11-25	1994-05-24	Trustees Of Dartmouth College	Lipocortin-1 receptor protein and its uses

1993
- 1993-05-11 CA CA002135390A patent/CA2135390A1/en not_active Abandoned
- 1993-05-11 ES ES93911273T patent/ES2168095T3/es not_active Expired - Lifetime
- 1993-05-11 DK DK93911273T patent/DK0731709T3/da active
- 1993-05-11 PT PT93911273T patent/PT731709E/pt unknown
- 1993-05-11 DE DE69331018T patent/DE69331018T2/de not_active Expired - Fee Related
- 1993-05-11 JP JP50371794A patent/JP3509860B2/ja not_active Expired - Fee Related
- 1993-05-11 EP EP93911273A patent/EP0731709B1/de not_active Expired - Lifetime
- 1993-05-11 MX MX9302750A patent/MX9302750A/es unknown
- 1993-05-11 AU AU42464/93A patent/AU687737B2/en not_active Ceased
- 1993-05-11 WO PCT/US1993/004502 patent/WO1993023063A1/en not_active Ceased
- 1993-05-11 AT AT93911273T patent/ATE207498T1/de not_active IP Right Cessation
- 1993-05-11 NZ NZ252591A patent/NZ252591A/en unknown
- 1993-05-11 US US08/060,433 patent/US6756211B1/en not_active Expired - Lifetime
1996
- 1996-10-23 NZ NZ299623A patent/NZ299623A/xx unknown
1999
- 1999-01-13 NZ NZ505450A patent/NZ505450A/en unknown

Also Published As

Publication number	Publication date
CA2135390A1 (en)	1993-11-25
NZ505450A (en)	2002-02-01
PT731709E (pt)	2002-04-29
MX9302750A (es)	1994-02-28
JPH07508177A (ja)	1995-09-14
DK0731709T3 (da)	2002-02-11
EP0731709A4 (de)	1997-06-11
WO1993023063A1 (en)	1993-11-25
NZ252591A (en)	1997-02-24
AU687737B2 (en)	1998-03-05
US6756211B1 (en)	2004-06-29
DE69331018D1 (de)	2001-11-29
ES2168095T3 (es)	2002-06-01
AU4246493A (en)	1993-12-13
EP0731709A1 (de)	1996-09-18
DE69331018T2 (de)	2002-06-13
EP0731709B1 (de)	2001-10-24
JP3509860B2 (ja)	2004-03-22
NZ299623A (en)	2000-11-24

Legal Events

Date	Code	Title	Description
2002-04-15	UEP	Publication of translation of european patent specification
2007-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
CA2129339A1 (en)	1993-08-19	Inhibitors of thrombosis
GEP20012446B (en)	2001-05-25	Inhibitors of Interleukin- 1β Converting Enzyme
EP0684830A4 (de)	1996-04-17	Inhibitoren gegen thrombose.
NO942064L (no)	1994-12-05	yminhibitorer
BG101841A (bg)	1998-04-30	Инхибитори на клетъчна адхезия
TR199801168T2 (xx)	1998-09-21	�nterleukin-1 beta d�n��t�r�c� enzim inhibit�rleri.
ATE318841T1 (de)	2006-03-15	Biarylalkansäuren in der verwendung als zelladhäsionsinhibitoren
DE69925508D1 (de)	2005-06-30	Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen
ATE237342T1 (de)	2003-05-15	Inhibitoren der leukozytenadhäsion
DK1029921T3 (da)	2003-02-24	Serpinresistent t-PA, mutanter, gener
KR950700323A (ko)	1995-01-16	엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 아미노아세틸머캅토아세틸아미드 유도체(Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE)
FI942625A0 (fi)	1994-06-03	Peptidisiä fosfinyylioksimetyyliketoneja interleukiini-1beta-muuttuvan entsyymin inhibiittoreina
ATE261932T1 (de)	2004-04-15	Inhibitoren der alpha-4 beta-1 vermittelten zelladhäsion
ATE207498T1 (de)	2001-11-15	Neutrophilen inhibitoren aus nematoden
DE68925032D1 (de)	1996-01-18	Leukozyten-adhäsions-inhibitor.
FI943511A7 (fi)	1994-07-26	Pyrroloimidatsolyyli- ja imidatsopyridinyylisubstituoidut 1H-bentsimidatsolijohdannaiset aromataasi-inhibiittoreina
ATE228760T1 (de)	2002-12-15	Thrombininhibitoren
FI943850A0 (fi)	1994-08-22	3-alkyylioksi-, aryylioksi- tai aryylialkyylioksibentso(b)tiofeeni-2-karboksamidit soluadheesion inhibiittoreina
MX9306686A (es)	1994-06-30	Factor anti-inflamatorio y metodo para su aislamiento.
ATE204478T1 (de)	2001-09-15	Inhibierung von leukozytenadhäsion
DK0787007T3 (da)	2002-04-22	Antiinflammatorisk faktor, isoleringsfremgangsmåde og anvendelse
NO954081L (no)	1995-12-13	Cytotoksisk faktor forbundet med disseminert sklerose, dens påvisning og kvantifisering
DE69332904D1 (de)	2003-05-28	Hemmung von hiv-infektion
ES2062332T3 (es)	1994-12-16	Benzoxazolonas antiinflamatorias.
ATE276272T1 (de)	2004-10-15	Entzündungshemmende peptide