ATE207738T1 - Verfahren zur baladung von lipidvesikeln - Google Patents

Verfahren zur baladung von lipidvesikeln

Info

Publication number
ATE207738T1
ATE207738T1 AT96902842T AT96902842T ATE207738T1 AT E207738 T1 ATE207738 T1 AT E207738T1 AT 96902842 T AT96902842 T AT 96902842T AT 96902842 T AT96902842 T AT 96902842T AT E207738 T1 ATE207738 T1 AT E207738T1
Authority
AT
Austria
Prior art keywords
methods
liposome formulations
preparation
stable
therapeutic agents
Prior art date
Application number
AT96902842T
Other languages
English (en)
Inventor
Michael Hope
Pieter R Cullis
David Fenske
Kim Wong
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of ATE207738T1 publication Critical patent/ATE207738T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT96902842T 1995-02-27 1996-02-27 Verfahren zur baladung von lipidvesikeln ATE207738T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/399,692 US5800833A (en) 1995-02-27 1995-02-27 Method for loading lipid vesicles
PCT/CA1996/000120 WO1996026715A1 (en) 1995-02-27 1996-02-27 Method for loading lipid vesicles

Publications (1)

Publication Number Publication Date
ATE207738T1 true ATE207738T1 (de) 2001-11-15

Family

ID=23580602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96902842T ATE207738T1 (de) 1995-02-27 1996-02-27 Verfahren zur baladung von lipidvesikeln

Country Status (7)

Country Link
US (2) US5800833A (de)
EP (1) EP0812186B1 (de)
AT (1) ATE207738T1 (de)
AU (1) AU4711296A (de)
CA (1) CA2213861C (de)
DE (1) DE69616523T2 (de)
WO (1) WO1996026715A1 (de)

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WO2013009928A1 (en) 2011-07-11 2013-01-17 Organic Medical Research Cannabinoid formulations
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US9717724B2 (en) 2012-06-13 2017-08-01 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies
AU2013202947B2 (en) 2012-06-13 2016-06-02 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
MX2015005992A (es) 2012-11-20 2016-03-07 Spectrum Pharmaceuticals Inc Metodo mejorado para la preparacion de la vincristina liposomal encapsulada para el uso terapeutico.
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TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
JP7042739B2 (ja) 2015-08-20 2022-03-28 イプセン バイオファーム リミティド 癌処置のためのリポソーム型イリノテカン及びｐａｒｐ阻害薬を使用する併用療法
TW202400181A (zh) 2015-08-21 2024-01-01 英商益普生生物製藥有限公司 使用包含微脂伊立替康(irinotecan)及奧沙利鉑(oxaliplatin)之組合療法治療轉移性胰臟癌的方法
EP4647126A3 (de) 2015-10-16 2026-02-11 Ipsen Biopharm Ltd. Stabilisierung von pharmazeutischen camptothecinzusammensetzungen
CN110402163A (zh) 2016-11-02 2019-11-01 易普森生物制药有限公司 使用包括脂质体伊立替康、奥沙利铂、5-氟尿嘧啶(和甲酰四氢叶酸)的组合疗法治疗胃癌
EP3773505B1 (de) 2018-03-30 2026-04-29 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
JP7449275B2 (ja) 2018-05-02 2024-03-13 インスメッド インコーポレイテッド リポソーム薬物製剤の製造方法
CA3183397A1 (en) 2020-06-18 2021-12-23 Daryl C. Drummond Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof
EP4188552A2 (de) 2020-07-28 2023-06-07 Jazz Pharmaceuticals Ireland Limited Kondensierte bicyclische raf-hemmer und verfahren zur verwendung davon
IL300110A (en) 2020-07-28 2023-03-01 Jazz Pharmaceuticals Ireland Ltd Chiral synthesis of fused bicyclic raf inhibitors
WO2022115645A1 (en) 2020-11-25 2022-06-02 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids, and related methods of use
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US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
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DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
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Also Published As

Publication number Publication date
US5785987A (en) 1998-07-28
CA2213861C (en) 2001-04-17
US5800833A (en) 1998-09-01
EP0812186A1 (de) 1997-12-17
CA2213861A1 (en) 1996-09-06
DE69616523D1 (de) 2001-12-06
AU4711296A (en) 1996-09-18
EP0812186B1 (de) 2001-10-31
WO1996026715A1 (en) 1996-09-06
DE69616523T2 (de) 2002-05-08

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