ATE207738T1 - Verfahren zur baladung von lipidvesikeln - Google Patents

Verfahren zur baladung von lipidvesikeln

Info

Publication number
ATE207738T1
ATE207738T1 AT96902842T AT96902842T ATE207738T1 AT E207738 T1 ATE207738 T1 AT E207738T1 AT 96902842 T AT96902842 T AT 96902842T AT 96902842 T AT96902842 T AT 96902842T AT E207738 T1 ATE207738 T1 AT E207738T1
Authority
AT
Austria
Prior art keywords
methods
liposome formulations
preparation
stable
therapeutic agents
Prior art date
Application number
AT96902842T
Other languages
English (en)
Inventor
Michael Hope
Pieter R Cullis
David Fenske
Kim Wong
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of ATE207738T1 publication Critical patent/ATE207738T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT96902842T 1995-02-27 1996-02-27 Verfahren zur baladung von lipidvesikeln ATE207738T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/399,692 US5800833A (en) 1995-02-27 1995-02-27 Method for loading lipid vesicles
PCT/CA1996/000120 WO1996026715A1 (en) 1995-02-27 1996-02-27 Method for loading lipid vesicles

Publications (1)

Publication Number Publication Date
ATE207738T1 true ATE207738T1 (de) 2001-11-15

Family

ID=23580602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96902842T ATE207738T1 (de) 1995-02-27 1996-02-27 Verfahren zur baladung von lipidvesikeln

Country Status (7)

Country Link
US (2) US5800833A (de)
EP (1) EP0812186B1 (de)
AT (1) ATE207738T1 (de)
AU (1) AU4711296A (de)
CA (1) CA2213861C (de)
DE (1) DE69616523T2 (de)
WO (1) WO1996026715A1 (de)

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US8772013B2 (en) 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
EP1718338B1 (de) 2004-02-02 2015-05-06 EnGeneIC Molecular Delivery Pty Ltd. Zusammensetzungen und verfahren für die gezielte arzneimittelabgabe in vitro und in vivo an säugetierzellen über von bakterien abstammende intakte minizellen
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AU2005303389A1 (en) * 2004-11-15 2006-05-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Combination therapy associating preferably a ceramide with a cytotoxic drug
EP1853303B1 (de) * 2005-02-14 2015-12-02 DPM Therapeutics Corporation Stabilisierte zusammensetzungen zur topischen verabreichung und herstellungsverfahren dafür
US7727537B2 (en) 2005-02-14 2010-06-01 Dpm Therapeutics Corp. Stabilized compositions for topical administration and methods of making same
US7838011B2 (en) 2005-02-14 2010-11-23 Pankaj Modi Stabilized protein compositions for topical administration and methods of making same
US20060280691A1 (en) * 2005-06-13 2006-12-14 University Of Alberta Spray freeze dried liposomal ciprofloxacin powder aerosol drug delivery
ES2798263T3 (es) 2005-12-08 2020-12-10 Insmed Inc Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares
US20090148506A1 (en) * 2005-12-22 2009-06-11 Awa Dicko Liposomal formulations comprising secondary and tertiary amines and methods for preparing thereof
WO2007117550A2 (en) 2006-04-06 2007-10-18 Transave, Inc. Methods for coacervation induced liposomal encapsulation and formulations thereof
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
WO2009097011A1 (en) 2007-08-17 2009-08-06 Celator Pharmaceuticals, Inc. Improved platinum drug formulations
WO2009072136A1 (en) * 2007-12-06 2009-06-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Particulate drug carriers as desensitizing agents
US20090281054A1 (en) * 2008-05-06 2009-11-12 Venkata Reddy Compositions and methods comprising capuramycin analogues
WO2010041255A2 (en) 2008-10-07 2010-04-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Liposomal systems comprising sphingomyelin
US8808734B2 (en) 2011-07-11 2014-08-19 Full Spectrum Laboratories Limited Cannabinoid formulations
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
AU2013202947B2 (en) 2012-06-13 2016-06-02 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
US9717724B2 (en) 2012-06-13 2017-08-01 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies
WO2014081887A1 (en) 2012-11-20 2014-05-30 Spectrum Pharmaceuticals Improved method for the preparation of liposome encapsulated vincristine for therapeutic use
CA2891487A1 (en) 2012-11-29 2014-06-05 Insmed Incorporated Stabilized vancomycin formulations
KR102310786B1 (ko) 2013-02-01 2021-10-12 존원 파마, 인코포레이티드 리포좀 내로 난수용성 약물의 원격 부하
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WO2015156246A1 (ja) * 2014-04-10 2015-10-15 サントリーホールディングス株式会社 コラーゲンペプチド含有組成物の苦味マスキング方法
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CN106999419A (zh) 2014-08-04 2017-08-01 佐尼奥尼制药股份有限公司 远程装载略微水溶性药物至脂质膜泡
US11318131B2 (en) 2015-05-18 2022-05-03 Ipsen Biopharm Ltd. Nanoliposomal irinotecan for use in treating small cell lung cancer
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
SG10201913073YA (en) 2015-08-20 2020-03-30 Ipsen Biopharm Ltd Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment
EP3791876A1 (de) 2015-08-21 2021-03-17 Ipsen Biopharm Ltd. Verfahren zur behandlung von metastasierendem bauchspeicheldrüsenkrebs mithilfe von kombinationstherapien mt liposomalem irinotecan und oxaliplatin
ES3036518T3 (en) 2015-10-16 2025-09-19 Ipsen Biopharm Ltd Stabilizing camptothecin pharmaceutical compositions
RU2761953C2 (ru) 2016-11-02 2021-12-14 Ипсен Биофарм Лтд. Лечение рака желудка с применением комбинационных видов терапии, содержащих липосомальный иринотекан, оксалиплатин, 5-фторурацил (и лейковорин)
EP3773505B1 (de) 2018-03-30 2026-04-29 Insmed Incorporated Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten
EP3787602A4 (de) 2018-05-02 2022-03-23 Insmed Incorporated Verfahren zur herstellung von liposomalen arzneimittelformulierungen
AU2021292747A1 (en) 2020-06-18 2023-02-23 Akagera Medicines, Inc. Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof
IL300110A (en) 2020-07-28 2023-03-01 Jazz Pharmaceuticals Ireland Ltd Chiral synthesis of fused bicyclic raf inhibitors
US11858930B2 (en) 2020-07-28 2024-01-02 Jazz Pharmaceuticals Ireland Limited Fused bicyclic RAF inhibitors and methods for use thereof
CN117098541A (zh) 2020-11-25 2023-11-21 阿卡格拉医药公司 用于递送核酸的脂质纳米粒及相关使用方法
CA3175913A1 (en) 2021-07-16 2023-01-16 Celator Pharmaceuticals, Inc. Liposomal formulations of bcl inhibitors
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DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE3713672A1 (de) * 1987-04-24 1988-11-17 Bayer Ag Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
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Also Published As

Publication number Publication date
EP0812186B1 (de) 2001-10-31
EP0812186A1 (de) 1997-12-17
DE69616523T2 (de) 2002-05-08
AU4711296A (en) 1996-09-18
DE69616523D1 (de) 2001-12-06
WO1996026715A1 (en) 1996-09-06
US5785987A (en) 1998-07-28
CA2213861A1 (en) 1996-09-06
US5800833A (en) 1998-09-01
CA2213861C (en) 2001-04-17

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