|
US6465188B1
(en)
*
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Nucleic acid ligand complexes
|
|
PT732929E
(pt)
|
1993-10-29 |
2008-08-26 |
Brigham & Womens Hospital |
Utilização terapêutica de ''engodos'' de elementos cis in vivo
|
|
US5670347A
(en)
|
1994-05-11 |
1997-09-23 |
Amba Biosciences Llc |
Peptide-mediated gene transfer
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
US8071737B2
(en)
*
|
1995-05-04 |
2011-12-06 |
Glead Sciences, Inc. |
Nucleic acid ligand complexes
|
|
US6229002B1
(en)
*
|
1995-06-07 |
2001-05-08 |
Nexstar Pharmaceuticlas, Inc. |
Platelet derived growth factor (PDGF) nucleic acid ligand complexes
|
|
US5994315A
(en)
*
|
1995-06-07 |
1999-11-30 |
East Carolina University |
Low adenosine agent, composition, kit and method for treatment of airway disease
|
|
US6699843B2
(en)
*
|
1995-06-07 |
2004-03-02 |
Gilead Sciences, Inc. |
Method for treatment of tumors using nucleic acid ligands to PDGF
|
|
US6007838A
(en)
†
|
1995-06-07 |
1999-12-28 |
The United States Of America As Represented By The Secretary Of The Army |
Process for making liposome preparation
|
|
FR2739292B1
(fr)
*
|
1995-09-28 |
1997-10-31 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations
|
|
US6344436B1
(en)
*
|
1996-01-08 |
2002-02-05 |
Baylor College Of Medicine |
Lipophilic peptides for macromolecule delivery
|
|
US6096336A
(en)
*
|
1996-01-30 |
2000-08-01 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
|
AU2112697A
(en)
*
|
1996-02-09 |
1997-08-28 |
Pi-Wan Cheng |
Receptor ligand-facilitated delivery of biologically active molecules
|
|
EP0906123A4
(de)
*
|
1996-03-15 |
1999-05-26 |
Univ Florida |
ANGIOTENSINOGEN-mRNA SPEZIFISCHE OLIGONUKLEOTIDE
|
|
CZ299809B6
(cs)
|
1996-05-08 |
2008-12-03 |
Nika Health Products Limited |
Lipidový vácek mající kladne nabitou membránu z lipidové dvojvrstvy pro prenos genetického materiálu a zpusob jeho prípravy
|
|
US6080728A
(en)
*
|
1996-07-16 |
2000-06-27 |
Mixson; A. James |
Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy
|
|
DE69736692T2
(de)
*
|
1996-07-16 |
2007-06-14 |
Archibald James Mixson |
Kationisches Vehikel: DNS Komplexe und ihre Verwendung in Gentherapie
|
|
US5837283A
(en)
|
1997-03-12 |
1998-11-17 |
The Regents Of The University Of California |
Cationic lipid compositions targeting angiogenic endothelial cells
|
|
US7112338B2
(en)
|
1997-03-12 |
2006-09-26 |
The Regents Of The University Of California |
Cationic liposome delivery of taxanes to angiogenic blood vessels
|
|
US7262173B2
(en)
|
1997-03-21 |
2007-08-28 |
Georgetown University |
Chemosensitizing with liposomes containing oligonucleotides
|
|
US6126965A
(en)
*
|
1997-03-21 |
2000-10-03 |
Georgetown University School Of Medicine |
Liposomes containing oligonucleotides
|
|
CA2294988C
(en)
|
1997-07-01 |
2015-11-24 |
Isis Pharmaceuticals Inc. |
Compositions and methods for the delivery of oligonucleotides via the alimentary canal
|
|
WO1999015643A2
(en)
*
|
1997-09-25 |
1999-04-01 |
University Of Florida |
ANTISENSE OLIGONUCLEOTIDE COMPOSITIONS TARGETED TO ANGIOTENSI N CONVERTING ENZYME mRNA AND METHODS OF USE
|
|
US6734171B1
(en)
*
|
1997-10-10 |
2004-05-11 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating nucleic acids in lipid bilayers
|
|
US6221425B1
(en)
|
1998-01-30 |
2001-04-24 |
Advanced Cardiovascular Systems, Inc. |
Lubricious hydrophilic coating for an intracorporeal medical device
|
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
|
US6472375B1
(en)
|
1998-04-16 |
2002-10-29 |
John Wayne Cancer Institute |
DNA vaccine and methods for its use
|
|
US6129757A
(en)
*
|
1998-05-18 |
2000-10-10 |
Scimed Life Systems |
Implantable members for receiving therapeutically useful compositions
|
|
WO1999060012A1
(en)
*
|
1998-05-21 |
1999-11-25 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for non-parenteral delivery of oligonucleotides
|
|
US7241617B2
(en)
*
|
1998-07-03 |
2007-07-10 |
Dnavec Research, Inc. |
Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci
|
|
US6135976A
(en)
|
1998-09-25 |
2000-10-24 |
Ekos Corporation |
Method, device and kit for performing gene therapy
|
|
US6958147B1
(en)
|
1998-10-26 |
2005-10-25 |
Licentia Ltd |
Use of VEGF-C to prevent restenosis
|
|
EP1141364A1
(de)
|
1999-01-08 |
2001-10-10 |
Amaxa GmbH |
Ausnutzung zelleigener transportsysteme zum transfer von nukleinsäuren durch die kernhülle
|
|
WO2000058511A1
(en)
*
|
1999-03-26 |
2000-10-05 |
Ludwig Institute For Cancer Research |
Screening and therapy for lymphatic disorders involving the flt4 receptor tyrosine kinase (vegfr-3)
|
|
US6764820B2
(en)
|
1999-03-26 |
2004-07-20 |
Ludwig Institute For Cancer Research |
Screening for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3)
|
|
WO2000059939A1
(en)
*
|
1999-04-05 |
2000-10-12 |
Adherex Technologies Inc. |
COMPOUNDS AND METHODS FOR STIMULATING β-CATENIN MEDIATED GENE EXPRESSION AND DIFFERENTIATION
|
|
US6352996B1
(en)
|
1999-08-03 |
2002-03-05 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
|
US6632800B1
(en)
*
|
1999-08-17 |
2003-10-14 |
Mayo Foundation For Medical Education And Research |
System for monitoring the expression of transgenes
|
|
US6586411B1
(en)
|
2000-08-16 |
2003-07-01 |
Mayo Foundation For Medical Education And Research |
System for monitoring the location of transgenes
|
|
WO2001013106A1
(en)
*
|
1999-08-17 |
2001-02-22 |
Mayo Foundation For Medical Education And Research |
System for monitoring the expression and/or location of transgenes
|
|
WO2001017511A1
(en)
*
|
1999-09-03 |
2001-03-15 |
Chugai Seiyaku Kabushiki Kaisha |
Method of intracellular sustained-release of drug and preparations
|
|
CN1182874C
(zh)
*
|
1999-10-29 |
2005-01-05 |
安增子摩祺株式会社 |
糖尿病性局部缺血疾病的基因治疗制剂
|
|
WO2001043778A1
(en)
*
|
1999-12-17 |
2001-06-21 |
Gene Therapy Systems, Inc. |
Use of cationic lipids for intracellular protein delivery
|
|
KR100774796B1
(ko)
*
|
2000-01-19 |
2007-11-07 |
가부시키가이샤 디나벡크 겐큐쇼 |
파라믹소바이러스 벡터의 혈관으로의 유전자 도입용도
|
|
AU2001239884B2
(en)
*
|
2000-02-25 |
2006-08-10 |
Vegenics Limited |
Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators
|
|
CA2418179A1
(en)
*
|
2000-07-26 |
2002-01-31 |
University Of Maryland, Baltimore |
The protein kinase domain of the large subunit of herpes simplex type 2 ribonucleotide reductase (icp10pk) has anti-apoptopic activity
|
|
JP2002142770A
(ja)
*
|
2000-11-08 |
2002-05-21 |
Dnavec Research Inc |
循環系への遺伝子送達用パラミクソウイルスベクター
|
|
EP1361896A2
(de)
*
|
2001-01-23 |
2003-11-19 |
Boston Scientific Corporation |
Methode zur lokalen myocardialen injektion zur behandlung ischämischen myocardiums
|
|
US6497896B2
(en)
|
2001-02-12 |
2002-12-24 |
Supergen, Inc. |
Method for administering camptothecins via injection of a pharmaceutical composition comprising microdroplets containing a camptothecin
|
|
US6509027B2
(en)
|
2001-02-12 |
2003-01-21 |
Supergen, Inc. |
Injectable pharmaceutical composition comprising coated particles of camptothecin
|
|
WO2003014338A1
(en)
*
|
2001-08-02 |
2003-02-20 |
Anges Mg, Inc. |
Process for producing inactivated virus envelope
|
|
US20040022727A1
(en)
*
|
2002-06-18 |
2004-02-05 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
US20040249130A1
(en)
*
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
CA2497313A1
(en)
*
|
2002-08-27 |
2004-04-29 |
Anges Mg, Inc. |
Biomolecule transfer method using virus envelope and composition and system therefor
|
|
US8853376B2
(en)
|
2002-11-21 |
2014-10-07 |
Archemix Llc |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
|
EP1566436A4
(de)
*
|
2002-11-21 |
2006-04-19 |
Genomidea Inc |
Verfahren zur isolierung von nukleinsäure mit erwünschter funktioneller eigenschaft und kit dafür
|
|
US20040204435A1
(en)
*
|
2003-04-09 |
2004-10-14 |
Joachim Liehr |
Alternating treatment with topoisomerase I and topoisomerase II inhibitors
|
|
WO2005004913A1
(ja)
*
|
2003-07-09 |
2005-01-20 |
Anges Mg, Inc. |
デコイを含む薬学的組成物およびその使用方法
|
|
DK1757312T3
(da)
*
|
2004-06-14 |
2011-04-11 |
Ishihara Sangyo Kaisha |
Frysetørret sammensætning af inaktiveret viruskappe med membranfusionsaktivitet
|
|
US8999944B2
(en)
|
2005-01-20 |
2015-04-07 |
University Of Rochester |
Thioredoxin interacting protein (TXNIP) as regulator of vascular function
|
|
EP1919944B1
(de)
|
2005-08-15 |
2011-03-23 |
Vegenics Pty Ltd |
Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften
|
|
US7875602B2
(en)
*
|
2005-10-21 |
2011-01-25 |
Sutter West Bay Hospitals |
Camptothecin derivatives as chemoradiosensitizing agents
|
|
AU2005339101B2
(en)
|
2005-12-14 |
2013-01-10 |
Herantis Pharma Plc. |
Novel neurotrophic factor protein and uses thereof
|
|
FI20070808A0
(fi)
|
2007-10-25 |
2007-10-25 |
Mart Saarma |
GDNF:n silmukointivariantit ja niiden käytöt
|
|
FI20080326A0
(fi)
|
2008-04-30 |
2008-04-30 |
Licentia Oy |
Neurotroofinen tekijä MANF ja sen käytöt
|
|
US8691212B2
(en)
|
2008-09-16 |
2014-04-08 |
Genomldea Inc. |
Therapeutic/prophylactic agent for prostate cancer
|
|
US9296790B2
(en)
|
2008-10-03 |
2016-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods and compositions for protein delivery
|
|
CN106390107B
(zh)
|
2009-06-10 |
2019-12-31 |
纽约大学 |
病理tau蛋白的免疫靶向
|
|
AU2010306940A1
(en)
|
2009-10-12 |
2012-06-07 |
Smith, Larry |
Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
|
|
WO2012031137A2
(en)
|
2010-09-02 |
2012-03-08 |
Mayo Foundation For Medical Education And Research |
Vesicular stomatitis viruses
|
|
US9951117B2
(en)
|
2010-09-02 |
2018-04-24 |
Mayo Foundation For Medical Education And Research |
Vesicular stomatitis viruses
|
|
WO2012092341A1
(en)
|
2010-12-28 |
2012-07-05 |
University Of Rochester |
Methods of modifying insulin signaling using biliverdin reductase (bvr) and bvr derived peptides
|
|
ES2586411T3
(es)
|
2011-03-04 |
2016-10-14 |
New York University |
Macrociclos sustitutos de enlace de hidrógeno como moduladores de Ras
|
|
AU2012255143A1
(en)
|
2011-05-19 |
2014-02-20 |
The Regents Of The University Of Michigan |
Integrin alpha-2 binding agents and use thereof to inhibit cancer cell proliferation
|
|
LT2753346T
(lt)
|
2011-09-07 |
2020-08-10 |
Mount Sinai School Of Medicine |
Ceramidazė ir ląstelių diferenciacija
|
|
PT2785683T
(pt)
|
2011-11-30 |
2020-04-16 |
Ludwig Inst For Cancer Res Ltd |
Moduladores de célula inkt e métodos para o seu uso
|
|
GB201120860D0
(en)
|
2011-12-05 |
2012-01-18 |
Cambridge Entpr Ltd |
Cancer immunotherapy
|
|
CN104334541A
(zh)
|
2012-02-16 |
2015-02-04 |
纽约大学 |
使用低聚氧代哌嗪非肽螺旋模拟物对低氧诱导基因表达的控制
|
|
AU2013240248B2
(en)
|
2012-03-26 |
2018-12-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Delivery of packaged RNA to mammalian cells
|
|
ES2897825T3
(es)
|
2012-06-01 |
2022-03-02 |
Icahn School Med Mount Sinai |
Niveles de ceramida en el tratamiento y prevención de infecciones
|
|
US9321749B1
(en)
|
2012-07-25 |
2016-04-26 |
Globavir Biosciences, Inc. |
Heterocyclic compounds and uses thereof
|
|
HUE054260T2
(hu)
|
2012-09-06 |
2021-08-30 |
Univ Chicago |
Antiszensz polinukleotidok exon-ugrás indukálására és eljárások disztrófiák kezelésére
|
|
WO2014063155A1
(en)
|
2012-10-21 |
2014-04-24 |
University Of Rochester |
Thy1 (cd90) as a novel therapy to control adipose tissue accumulation
|
|
EP2912178B1
(de)
|
2012-10-25 |
2020-06-17 |
Whitehead Institute For Biomedical Research |
Superverstärker und verfahren zur verwendung davon
|
|
WO2014125291A1
(en)
|
2013-02-14 |
2014-08-21 |
Ucl Business Plc |
Agents which induce lymphangiogenesis for use in the treatment of cystic kidney disease
|
|
RS60026B1
(sr)
|
2013-02-18 |
2020-04-30 |
Vegenics Pty Ltd |
Molekuli koji vezuju ligande i njihove upotrebe
|
|
PT2968479T
(pt)
|
2013-03-14 |
2019-08-07 |
Icahn School Med Mount Sinai |
Composições terapêuticas de ceramidase ácida e métodos de fabrico e utilização
|
|
WO2014191630A2
(en)
|
2013-05-28 |
2014-12-04 |
Helsingin Yliopisto |
Non-human animal model encoding a non-functional manf gene
|
|
WO2015024022A2
(en)
|
2013-08-16 |
2015-02-19 |
University Of Rochester |
Designed peptides for tight junction barrier modulation
|
|
CN106232807A
(zh)
|
2013-12-16 |
2016-12-14 |
美利坚合众国, 由健康及人类服务部部长代表 |
通过使用vlp复制子投递ii类mhc抗原的癌症免疫疗法
|
|
PT3283500T
(pt)
|
2015-04-08 |
2021-01-28 |
Univ Chicago |
Composições e métodos para corrigir distrofia muscular das cinturas tipo 2c com utilização de salto do exão
|
|
US10508134B2
(en)
|
2015-05-01 |
2019-12-17 |
Onl Therapeutics, Inc. |
Peptide compositions and methods of use
|
|
EP3371211B1
(de)
|
2015-11-04 |
2025-01-01 |
Icahn School of Medicine at Mount Sinai |
Rho-assoziierte proteinkinasehemmer zur behandlung von tumoren und krebs sowie identifizierung von kandidatenpatienten für solch eine behandlung
|
|
WO2017189730A1
(en)
|
2016-04-26 |
2017-11-02 |
Icahn School Of Medicine At Mount Sinai |
Treatment of hippo pathway mutant tumors and methods of identifying subjects as candidates for treatment
|
|
WO2018084185A1
(ja)
|
2016-11-01 |
2018-05-11 |
国立大学法人大阪大学 |
Hvj-eおよび免疫チェックポイントタンパク質の阻害物質を含む抗がん剤
|
|
ES2896255T3
(es)
|
2016-12-06 |
2022-02-24 |
Univ Osaka |
Nuevo agente terapéutico para enfermedades por prionoides
|
|
MX2020008377A
(es)
|
2018-03-27 |
2020-09-25 |
Enzyvant Therapeutics Gmbh |
Marcadores de la enfermedad de farber y usos de estos.
|
|
MX2020013450A
(es)
|
2018-06-11 |
2021-08-11 |
Univ Florida |
Materiales y métodos para tratar el cancer y los trastornos relacionados con el estrés.
|
|
CA3103675A1
(en)
|
2018-06-21 |
2019-12-26 |
University Of Rochester |
Methods of treating or inhibiting onset of huntington's disease
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
US20220088158A1
(en)
|
2019-01-23 |
2022-03-24 |
Aceragen, Inc. |
Method of ameliorating a pro-inflammatory immunophenotype in farber disease subjects by repeated administration of a recombinant human acid ceramidase
|
|
US20230057355A1
(en)
|
2019-02-13 |
2023-02-23 |
University Of Rochester |
Gene networks that mediate remyelination of the human brain
|
|
US20220249364A1
(en)
|
2019-06-05 |
2022-08-11 |
University Of Rochester |
Designed Inhibitors of Tight Junction Formation
|
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
JP2023546359A
(ja)
|
2020-10-06 |
2023-11-02 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
腫瘍浸潤リンパ球療法によるnsclc患者の治療
|
|
EP4262827A1
(de)
|
2020-12-17 |
2023-10-25 |
Iovance Biotherapeutics, Inc. |
Behandlung von krebs mit tumorinfiltrierenden lymphozyten
|
|
AU2021401302A1
(en)
|
2020-12-17 |
2023-07-06 |
Iovance Biotherapeutics, Inc. |
Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors
|
|
CA3215830A1
(en)
|
2021-04-19 |
2022-10-27 |
Rafael CUBAS |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
|
JP2024527961A
(ja)
|
2021-07-28 |
2024-07-26 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Kras阻害剤と併用した腫瘍浸潤リンパ球療法によるがん患者の治療
|
|
WO2023077015A2
(en)
|
2021-10-27 |
2023-05-04 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
EP4426331A1
(de)
|
2021-11-02 |
2024-09-11 |
University of Rochester |
Tcf7l2-vermittelte remyelinisierung im gehirn
|
|
CA3237410A1
(en)
|
2021-11-10 |
2023-05-19 |
Friedrich Graf Finck VON FINCKENSTEIN |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
|
WO2023192998A1
(en)
|
2022-04-01 |
2023-10-05 |
Icahn School Of Medicine At Mount Sinai |
Treating orthopedic injury with a vector driving expression of acid ceramidase
|
|
JP2025512401A
(ja)
|
2022-04-15 |
2025-04-17 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
特定のサイトカインの組み合わせ及び/またはAKTi処理を使用したTIL拡張プロセス
|
|
EP4658294A2
(de)
|
2023-02-02 |
2025-12-10 |
University of Rochester |
Kompetitiver ersatz von gliazellen
|
|
EP4704807A1
(de)
|
2023-05-03 |
2026-03-11 |
IOX Therapeutics Limited |
Liposomale inkt-zellmodulatorzusammensetzungen und verfahren zur verwendung
|
|
TW202540200A
(zh)
|
2023-12-01 |
2025-10-16 |
美商基利科學股份有限公司 |
抗fap-light融合蛋白及其用途
|
|
WO2025259871A1
(en)
|
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2025-12-18 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
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