ATE207871T1 - Verfahren zur herstellung von einem naphthalenaminderivat - Google Patents
Verfahren zur herstellung von einem naphthalenaminderivatInfo
- Publication number
- ATE207871T1 ATE207871T1 AT97951338T AT97951338T ATE207871T1 AT E207871 T1 ATE207871 T1 AT E207871T1 AT 97951338 T AT97951338 T AT 97951338T AT 97951338 T AT97951338 T AT 97951338T AT E207871 T1 ATE207871 T1 AT E207871T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- dichlorophenyl
- tetrahydro
- methyl
- acid addition
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/40—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of hydroxylamino or oxyimino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9603493A HU222341B1 (hu) | 1996-12-18 | 1996-12-18 | Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier |
| PCT/HU1997/000083 WO1998027050A1 (en) | 1996-12-18 | 1997-12-15 | Process for preparing a naphtalenamine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE207871T1 true ATE207871T1 (de) | 2001-11-15 |
Family
ID=89994564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97951338T ATE207871T1 (de) | 1996-12-18 | 1997-12-15 | Verfahren zur herstellung von einem naphthalenaminderivat |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6034274A (de) |
| EP (1) | EP0946493B1 (de) |
| AT (1) | ATE207871T1 (de) |
| AU (1) | AU5493198A (de) |
| DE (1) | DE69707914T2 (de) |
| DK (1) | DK0946493T3 (de) |
| ES (1) | ES2166566T3 (de) |
| HU (1) | HU222341B1 (de) |
| PT (1) | PT946493E (de) |
| WO (1) | WO1998027050A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2217748T3 (es) | 1998-03-18 | 2004-11-01 | Ciba Specialty Chemicals Holding Inc. | Procedimiento para la hidrogenacin catalitica cis-selectiva de ciclohexilidenaminas. |
| EP1632473A1 (de) * | 1998-11-27 | 2006-03-08 | Teva Pharmaceutical Industries Ltd | Polymorphe des Sertralin-Hydrochlorids |
| WO2001009080A1 (en) | 1999-07-29 | 2001-02-08 | Ciba Specialty Chemicals Holding Inc. | Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines |
| TWI260315B (en) | 1999-10-29 | 2006-08-21 | Ciba Sc Holding Ag | Polymorphic forms of sertraline hydrochloride |
| US7442838B2 (en) | 1999-10-29 | 2008-10-28 | Ciba Specialty Chemicals Corp. | Polymorphic forms of sertraline hydrochloride |
| IN187170B (de) | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
| IL151691A0 (en) | 2000-03-14 | 2003-04-10 | Teva Pharma | Novel process for preparing (+)-cis-sertraline |
| EP1397342A1 (de) * | 2001-05-31 | 2004-03-17 | Orion Corporation Fermion | Verfahren zur herstellung von sertralinzwischenprodukten |
| WO2003093217A1 (en) | 2002-04-29 | 2003-11-13 | Teva Pharmaceutical Industries Ltd. | Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof |
| WO2004092110A2 (en) * | 2003-04-14 | 2004-10-28 | Teva Pharmaceutical Industries Ltd. | Hydrogenation of imine intermediates of sertraline with catalysts |
| CA2537804A1 (en) * | 2003-09-05 | 2005-03-17 | Teva Pharmaceutical Industries Ltd | A recycling process for preparing sertraline |
| US7345201B2 (en) | 2005-02-23 | 2008-03-18 | Teva Pharmaceutical Industries, Ltd. | Processes for preparing sertraline |
| EP1885683A2 (de) | 2005-06-03 | 2008-02-13 | Hetero Drugs Limited | Hochstereoselektive synthese von sertralin |
| US7893053B2 (en) * | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556676A (en) * | 1979-11-01 | 1985-12-03 | Pfizer Inc. | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US5082970A (en) * | 1991-03-06 | 1992-01-21 | Pfizer Inc. | Process for recycling amine isomer |
| US5248699A (en) * | 1992-08-13 | 1993-09-28 | Pfizer Inc. | Sertraline polymorph |
-
1996
- 1996-12-18 HU HU9603493A patent/HU222341B1/hu active IP Right Grant
-
1997
- 1997-12-15 AU AU54931/98A patent/AU5493198A/en not_active Abandoned
- 1997-12-15 US US09/319,879 patent/US6034274A/en not_active Expired - Fee Related
- 1997-12-15 AT AT97951338T patent/ATE207871T1/de not_active IP Right Cessation
- 1997-12-15 DE DE69707914T patent/DE69707914T2/de not_active Expired - Fee Related
- 1997-12-15 WO PCT/HU1997/000083 patent/WO1998027050A1/en not_active Ceased
- 1997-12-15 PT PT97951338T patent/PT946493E/pt unknown
- 1997-12-15 ES ES97951338T patent/ES2166566T3/es not_active Expired - Lifetime
- 1997-12-15 EP EP97951338A patent/EP0946493B1/de not_active Expired - Lifetime
- 1997-12-15 DK DK97951338T patent/DK0946493T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| HU222341B1 (hu) | 2003-06-28 |
| DE69707914T2 (de) | 2002-04-25 |
| EP0946493B1 (de) | 2001-10-31 |
| AU5493198A (en) | 1998-07-15 |
| HU9603493D0 (en) | 1997-02-28 |
| WO1998027050A1 (en) | 1998-06-25 |
| DK0946493T3 (da) | 2002-02-11 |
| ES2166566T3 (es) | 2002-04-16 |
| PT946493E (pt) | 2002-03-28 |
| EP0946493A1 (de) | 1999-10-06 |
| DE69707914D1 (de) | 2001-12-06 |
| US6034274A (en) | 2000-03-07 |
| HUP9603493A2 (hu) | 1999-06-28 |
| HUP9603493A3 (en) | 1999-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |