ATE209655T1 - Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung - Google Patents

Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung

Info

Publication number
ATE209655T1
ATE209655T1 AT95931574T AT95931574T ATE209655T1 AT E209655 T1 ATE209655 T1 AT E209655T1 AT 95931574 T AT95931574 T AT 95931574T AT 95931574 T AT95931574 T AT 95931574T AT E209655 T1 ATE209655 T1 AT E209655T1
Authority
AT
Austria
Prior art keywords
preparation
polynucleotide reagents
polynucleotides
reagents
nucleotide groups
Prior art date
Application number
AT95931574T
Other languages
English (en)
Inventor
Michael S Urdea
Thomas Horn
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE209655T1 publication Critical patent/ATE209655T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Furan Compounds (AREA)
AT95931574T 1994-08-25 1995-08-24 Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung ATE209655T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/296,368 US5597909A (en) 1994-08-25 1994-08-25 Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
PCT/US1995/010776 WO1996006104A1 (en) 1994-08-25 1995-08-24 Polynucleotide reagents having nonnucleotidic moieties, and associated methods of synthesis and use

Publications (1)

Publication Number Publication Date
ATE209655T1 true ATE209655T1 (de) 2001-12-15

Family

ID=23141731

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95931574T ATE209655T1 (de) 1994-08-25 1995-08-24 Polynukleotid reagenzien mit nichtnukleotidischen gruppierungen, deren herstellung und verwendung

Country Status (10)

Country Link
US (2) US5597909A (de)
EP (1) EP0777674B1 (de)
JP (2) JPH10504719A (de)
AT (1) ATE209655T1 (de)
AU (1) AU3494595A (de)
CA (1) CA2196806A1 (de)
DE (1) DE69524232T2 (de)
ES (1) ES2169149T3 (de)
MX (1) MX9701293A (de)
WO (1) WO1996006104A1 (de)

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JP2006068022A (ja) 2006-03-16
AU3494595A (en) 1996-03-14
MX9701293A (es) 1997-05-31
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CA2196806A1 (en) 1996-02-29
JPH10504719A (ja) 1998-05-12
US5594117A (en) 1997-01-14
WO1996006104A1 (en) 1996-02-29
DE69524232D1 (de) 2002-01-10
EP0777674A1 (de) 1997-06-11
US5597909A (en) 1997-01-28
EP0777674B1 (de) 2001-11-28

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