ATE209898T1 - Feste arzneizubereitung - Google Patents

Feste arzneizubereitung

Info

Publication number: ATE209898T1
Authority: AT; Austria
Prior art keywords: medicinal preparation; solid medicinal; group; reduced; maltitol
Prior art date: 1997-05-27

Application number

AT98921808T

Other languages

English (en)

Inventor

Toshihiro Shimizu

Masae Sugaya

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-27

Filing date

1998-05-26

Publication date

2001-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15182020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE209898(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-05-26 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE209898T1 publication Critical patent/ATE209898T1/de

Links

238000002360 preparation method Methods 0.000 title abstract 2
239000007787 solid Substances 0.000 title abstract 2
PVXPPJIGRGXGCY-DJHAAKORSA-N 6-O-alpha-D-glucopyranosyl-alpha-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@](O)(CO)O1 PVXPPJIGRGXGCY-DJHAAKORSA-N 0.000 abstract 1
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
239000004386 Erythritol Substances 0.000 abstract 1
UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 abstract 1
229920002472 Starch Polymers 0.000 abstract 1
TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
150000001720 carbohydrates Chemical class 0.000 abstract 1
238000004090 dissolution Methods 0.000 abstract 1
UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 abstract 1
235000019414 erythritol Nutrition 0.000 abstract 1
229940009714 erythritol Drugs 0.000 abstract 1
-1 hydroxypropoxyl group Chemical group 0.000 abstract 1
229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 abstract 1
239000000845 maltitol Substances 0.000 abstract 1
235000010449 maltitol Nutrition 0.000 abstract 1
VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 abstract 1
229940035436 maltitol Drugs 0.000 abstract 1
HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
239000000600 sorbitol Substances 0.000 abstract 1
235000019698 starch Nutrition 0.000 abstract 1
239000008107 starch Substances 0.000 abstract 1
150000005846 sugar alcohols Chemical class 0.000 abstract 1
239000000811 xylitol Substances 0.000 abstract 1
235000010447 xylitol Nutrition 0.000 abstract 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
229960002675 xylitol Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Zoology (AREA)
Biophysics (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT98921808T 1997-05-27 1998-05-26 Feste arzneizubereitung ATE209898T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP13672497		1997-05-27
PCT/JP1998/002298 WO1998053798A1 (en)	1997-05-27	1998-05-26	Solid pharmaceutical preparation

Publications (1)

Publication Number	Publication Date
ATE209898T1 true ATE209898T1 (de)	2001-12-15

Family

ID=15182020

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98921808T ATE209898T1 (de)	1997-05-27	1998-05-26	Feste arzneizubereitung

Country Status (12)

Country	Link
US (2)	US6299904B1 (de)
EP (1)	EP0996424B1 (de)
JP (1)	JP2009292843A (de)
KR (1)	KR100490969B1 (de)
CN (1)	CN1130194C (de)
AT (1)	ATE209898T1 (de)
AU (1)	AU7451198A (de)
CA (1)	CA2286753C (de)
DE (1)	DE69802810T2 (de)
ES (1)	ES2164424T3 (de)
TW (1)	TW580397B (de)
WO (1)	WO1998053798A1 (de)

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1998
- 1998-05-25 TW TW087108023A patent/TW580397B/zh not_active IP Right Cessation
- 1998-05-26 KR KR10-1999-7010036A patent/KR100490969B1/ko not_active Expired - Fee Related
- 1998-05-26 CA CA002286753A patent/CA2286753C/en not_active Expired - Lifetime
- 1998-05-26 CN CN98805424A patent/CN1130194C/zh not_active Expired - Fee Related
- 1998-05-26 AT AT98921808T patent/ATE209898T1/de active
- 1998-05-26 ES ES98921808T patent/ES2164424T3/es not_active Expired - Lifetime
- 1998-05-26 DE DE69802810T patent/DE69802810T2/de not_active Expired - Lifetime
- 1998-05-26 US US09/424,434 patent/US6299904B1/en not_active Expired - Lifetime
- 1998-05-26 WO PCT/JP1998/002298 patent/WO1998053798A1/en not_active Ceased
- 1998-05-26 EP EP98921808A patent/EP0996424B1/de not_active Expired - Lifetime
- 1998-05-26 AU AU74511/98A patent/AU7451198A/en not_active Abandoned
2001
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2009
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Also Published As

Publication number	Publication date
EP0996424A1 (de)	2000-05-03
EP0996424B1 (de)	2001-12-05
US6586004B2 (en)	2003-07-01
CA2286753C (en)	2006-01-17
US6299904B1 (en)	2001-10-09
TW580397B (en)	2004-03-21
CA2286753A1 (en)	1998-12-03
CN1130194C (zh)	2003-12-10
KR100490969B1 (ko)	2005-05-24
KR20010020412A (ko)	2001-03-15
ES2164424T3 (es)	2002-02-16
JP2009292843A (ja)	2009-12-17
CN1257422A (zh)	2000-06-21
US20010009678A1 (en)	2001-07-26
WO1998053798A1 (en)	1998-12-03
DE69802810T2 (de)	2002-04-18
AU7451198A (en)	1998-12-30
DE69802810D1 (de)	2002-01-17

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