NO902394L - Fremgangsmaate for fremstilling av pyranyl-cyanoguanidin-derivater. - Google Patents

Fremgangsmaate for fremstilling av pyranyl-cyanoguanidin-derivater.

Info

Publication number: NO902394L
Authority: NO; Norway
Prior art keywords: pyranyl; procedure; preparation; cyanoguanidine derivatives; chem
Prior art date: 1989-05-31

Application number

NO90902394A

Other languages

English (en)

Other versions

NO902394D0 (no

NO174807B (no

NO174807C (no

Inventor

Karnail Atwal

Gary James Grover

Kyoung Soon Kim

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-31

Filing date

1990-05-30

Publication date

1990-12-03

1990-05-30 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1990-05-30 Publication of NO902394D0 publication Critical patent/NO902394D0/no

1990-12-03 Publication of NO902394L publication Critical patent/NO902394L/no

1994-04-05 Publication of NO174807B publication Critical patent/NO174807B/no

1994-07-13 Publication of NO174807C publication Critical patent/NO174807C/no

Links

PSUZFEOOWHGNNG-UHFFFAOYSA-N 1-cyano-1-(2h-pyran-2-yl)guanidine Chemical class NC(=N)N(C#N)C1OC=CC=C1 PSUZFEOOWHGNNG-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
230000003213 activating effect Effects 0.000 abstract 1
230000002253 anti-ischaemic effect Effects 0.000 abstract 1
229940125692 cardiovascular agent Drugs 0.000 abstract 1
239000002327 cardiovascular agent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
108010083133 potassium channel protein I(sk) Proteins 0.000 abstract 1
IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrane Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Liquid Crystal Substances (AREA)

NO902394A 1989-05-31 1990-05-30 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyranyl-cyanoguanidin-derivater NO174807B (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US35923689A	1989-05-31	1989-05-31
US49306090A	1990-03-13	1990-03-13

Publications (4)

Publication Number	Publication Date
NO902394D0 NO902394D0 (no)	1990-05-30
NO902394L true NO902394L (no)	1990-12-03
NO174807B NO174807B (no)	1994-04-05
NO174807C NO174807C (no)	1994-07-13

Family

ID=27000402

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902394A NO174807B (no)	1989-05-31	1990-05-30	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyranyl-cyanoguanidin-derivater

Country Status (22)

Country	Link
EP (1)	EP0401010B1 (no)
JP (2)	JPH0327375A (no)
KR (1)	KR950006155B1 (no)
CN (1)	CN1047672A (no)
AT (1)	ATE141598T1 (no)
AU (1)	AU633082B2 (no)
CA (1)	CA2015296C (no)
DE (1)	DE69028143T2 (no)
DK (1)	DK0401010T3 (no)
EG (1)	EG19389A (no)
ES (1)	ES2090099T3 (no)
FI (1)	FI109120B (no)
GR (1)	GR3021702T3 (no)
HK (1)	HK16997A (no)
HU (1)	HU207857B (no)
IE (1)	IE901793A1 (no)
IL (1)	IL94326A (no)
NO (1)	NO174807B (no)
NZ (1)	NZ233845A (no)
PL (4)	PL166230B1 (no)
PT (1)	PT94210B (no)
RU (1)	RU2057129C1 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU631588B2 (en) *	1988-12-23	1992-12-03	Beecham Group Plc	Benzopyran derivatives and related compounds
US5104890A (en) *	1989-03-28	1992-04-14	Fujisawa Pharmaceutical Company, Ltd.	Benzopyran derivatives and processes for preparation thereof
CA2015296C (en) *	1989-05-31	2001-08-07	Karnail Atwal	Pyranyl cyanoguanidine derivatives
US5140031A (en) *	1989-05-31	1992-08-18	E. R. Squibb & Sons, Inc.	Pyranyl cyanoguanidine derivatives
FR2657872B2 (fr) *	1989-11-06	1992-06-12	Sanofi Sa	Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
DE69019350T2 (de) *	1990-05-17	1996-02-15	Union Camp Patent Holding, Inc., Wilmington, Del.	Umweltfreundlicheres verfahren zum bleichen von lignocellulosischen materialien.
AU651105B2 (en) *	1990-06-18	1994-07-14	E.R. Squibb & Sons, Inc.	Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
US5643921A (en) *	1990-09-26	1997-07-01	E.R. Squibb & Sons, Inc.	Cardiopulmonary bypass and organ transplant using a potassium channel activator
ZA918999B (en) *	1990-12-05	1992-08-26	Squibb & Sons Inc	Method of treating shock using a potassium channel activator
DE4120322A1 (de) *	1991-06-20	1992-12-24	Bayer Ag	Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5374643A (en) *	1992-09-11	1994-12-20	E. R. Squibb & Sons, Inc.	Aryl urea (thiourea) and cyanoguanidine derivatives
IL109229A0 (en) *	1993-05-11	1994-07-31	Bristol Myers Squibb Co	Heterocyclic compounds and processes for the preparation of pyranyl cyanoguanidine derivatives using the same
US5478734A (en) *	1993-06-18	1995-12-26	Bristol-Myers Squibb Company	Method of chiral epoxidation of benzopyran or pyranopyridine derivatives using microorganisms
US5612323A (en) *	1995-06-07	1997-03-18	Bristol-Myers Squibb Company	Phosphinic ester substituted benzopyran derivatives
US5869478A (en) *	1995-06-07	1999-02-09	Bristol-Myers Squibb Company	Sulfonamido substituted benzopyran derivatives
US5612370A (en) *	1995-06-07	1997-03-18	Bristol-Myers Squibb Company	Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) *	1995-06-07	1997-05-13	Bristol-Myers Squibb Company	Process for preparing 4-arylamino-benzopyran and related compounds
DE19742508A1 (de) *	1997-09-26	1999-04-01	Hoechst Marion Roussel De Gmbh	Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
KR100429609B1 (ko) *	1999-10-21	2004-05-03	동부한농화학 주식회사	벤조피라닐 구아니딘 유도체, 그의 제조방법 및 그를포함하는 약학적 조성물
WO2001029023A1 (en) *	1999-10-21	2001-04-26	Korea Research Institute Of Chemical Technology	Benzopyranyl guanidine derivatives, process for preparation thereof, and pharmaceutical compositions containing them
CN1854135B (zh) *	2005-04-18	2013-06-12	李伟章	由氰基胍连接组成的杂环化合物及其医药应用
WO2007022964A2 (de)	2005-08-24	2007-03-01	Abbott Gmbh & Co. Kg	Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
KR101619564B1 (ko) *	2009-04-23	2016-05-10	바이엘 파마 악티엔게젤샤프트	Ｆ-18 표지 ｐｅｔ 추적자에 관한 신규 전구체 분자

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3682331D1 (de) *	1985-06-08	1991-12-12	Beecham Group Plc	Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
GB8521857D0 (en) *	1985-09-03	1985-10-09	Beecham Group Plc	Active compounds
JPH027217A (ja) *	1988-04-30	1990-01-11	Mitsubishi Electric Corp	磁気記録再生装置
US4988723A (en) *	1988-06-02	1991-01-29	Fujisawa Pharmaceutical Co., Ltd.	Benzopyran derivatives and their use as anti-hypertensives
DE3823533A1 (de) *	1988-07-12	1990-02-08	Beiersdorf Ag	Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE68926729T2 (de) *	1988-09-16	1997-02-13	Beecham Group Plc	Benzopyranderivate mit einer blutdrucksenkenden Wirkung
JPH02172984A (ja) *	1988-12-23	1990-07-04	Yamanouchi Pharmaceut Co Ltd	クロマン誘導体
US5104890A (en) *	1989-03-28	1992-04-14	Fujisawa Pharmaceutical Company, Ltd.	Benzopyran derivatives and processes for preparation thereof
CA2015296C (en) *	1989-05-31	2001-08-07	Karnail Atwal	Pyranyl cyanoguanidine derivatives

1990
- 1990-04-24 CA CA002015296A patent/CA2015296C/en not_active Expired - Lifetime
- 1990-04-30 AU AU54552/90A patent/AU633082B2/en not_active Ceased
- 1990-05-08 IL IL9432690A patent/IL94326A/xx not_active IP Right Cessation
- 1990-05-18 IE IE179390A patent/IE901793A1/en unknown
- 1990-05-29 NZ NZ233845A patent/NZ233845A/en unknown
- 1990-05-30 JP JP2143243A patent/JPH0327375A/ja active Pending
- 1990-05-30 PT PT94210A patent/PT94210B/pt not_active IP Right Cessation
- 1990-05-30 RU SU904830194A patent/RU2057129C1/ru not_active IP Right Cessation
- 1990-05-30 EG EG31990A patent/EG19389A/xx active
- 1990-05-30 NO NO902394A patent/NO174807B/no not_active IP Right Cessation
- 1990-05-30 KR KR1019900007840A patent/KR950006155B1/ko not_active Expired - Fee Related
- 1990-05-30 HU HU903271A patent/HU207857B/hu not_active IP Right Cessation
- 1990-05-31 PL PL90290036A patent/PL166230B1/pl not_active IP Right Cessation
- 1990-05-31 PL PL90290035A patent/PL166174B1/pl not_active IP Right Cessation
- 1990-05-31 AT AT90305920T patent/ATE141598T1/de not_active IP Right Cessation
- 1990-05-31 ES ES90305920T patent/ES2090099T3/es not_active Expired - Lifetime
- 1990-05-31 FI FI902710A patent/FI109120B/fi active IP Right Grant
- 1990-05-31 PL PL90285415A patent/PL166007B1/pl not_active IP Right Cessation
- 1990-05-31 EP EP90305920A patent/EP0401010B1/en not_active Expired - Lifetime
- 1990-05-31 CN CN90103959A patent/CN1047672A/zh active Pending
- 1990-05-31 DE DE69028143T patent/DE69028143T2/de not_active Expired - Fee Related
- 1990-05-31 PL PL90290037A patent/PL166192B1/pl not_active IP Right Cessation
- 1990-05-31 DK DK90305920.2T patent/DK0401010T3/da active
1991
- 1991-06-28 JP JP3158327A patent/JPH05239049A/ja active Pending
1996
- 1996-11-19 GR GR960403095T patent/GR3021702T3/el unknown
1997
- 1997-02-13 HK HK16997A patent/HK16997A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR900018064A (ko)	1990-12-20
PL166174B1 (pl)	1995-04-28
IE901793A1 (en)	1991-09-25
RU2057129C1 (ru)	1996-03-27
HU9003271D0 (en)	1990-10-28
FI902710A0 (fi)	1990-05-31
DE69028143T2 (de)	1997-01-23
PL166230B1 (pl)	1995-04-28
HU207857B (en)	1993-06-28
PL166192B1 (pl)	1995-04-28
CN1047672A (zh)	1990-12-12
ES2090099T3 (es)	1996-10-16
IL94326A (en)	1995-12-08
JPH05239049A (ja)	1993-09-17
PT94210A (pt)	1991-02-08
CA2015296C (en)	2001-08-07
KR950006155B1 (ko)	1995-06-09
IE901793L (en)	1990-11-30
CA2015296A1 (en)	1990-11-30
NO902394D0 (no)	1990-05-30
AU5455290A (en)	1990-12-06
NZ233845A (en)	1994-09-27
PT94210B (pt)	1997-07-31
NO174807B (no)	1994-04-05
DE69028143D1 (de)	1996-09-26
DK0401010T3 (da)	1996-09-16
AU633082B2 (en)	1993-01-21
PL285415A1 (en)	1991-09-09
EP0401010A3 (en)	1991-05-02
PL166007B1 (pl)	1995-03-31
GR3021702T3 (en)	1997-02-28
EP0401010A2 (en)	1990-12-05
EP0401010B1 (en)	1996-08-21
NO174807C (no)	1994-07-13
EG19389A (en)	1995-02-28
HUT55055A (en)	1991-04-29
ATE141598T1 (de)	1996-09-15
JPH0327375A (ja)	1991-02-05
HK16997A (en)	1997-02-13
FI109120B (fi)	2002-05-31
IL94326A0 (en)	1991-03-10

Legal Events

Date	Code	Title	Description
2010-06-07	MK1K	Patent expired

Publication	Publication Date	Title
NO902394D0 (no)	1990-05-30	Fremgangsmaate for fremstilling av pyranyl-cyanoguanidin-derivater.
MX9200817A (es)	1992-08-01	Derivados de piranil cianoguanidina y proceso para su preparacion.
ATE21105T1 (de)	1986-08-15	7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.
DK506587D0 (da)	1987-09-25	Imidderivater
AU600054B2 (en)	1990-08-02	2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m- phenylene pgi2 derivatives
DK0389162T3 (da)	1994-02-14	2,5,6,7-Tetranor-4,8-inter-m-phenylen PGI2 derivater
DE3173404D1 (en)	1986-02-13	Biologically active heterobicyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof
GR3002699T3 (en)	1993-01-25	Process for stabilising procaterol