ATE211484T1 - Zyklische peptideverbindungen zur schmerzbehandlung und ihr herstellungsverfahren - Google Patents

Zyklische peptideverbindungen zur schmerzbehandlung und ihr herstellungsverfahren

Info

Publication number
ATE211484T1
ATE211484T1 AT97309757T AT97309757T ATE211484T1 AT E211484 T1 ATE211484 T1 AT E211484T1 AT 97309757 T AT97309757 T AT 97309757T AT 97309757 T AT97309757 T AT 97309757T AT E211484 T1 ATE211484 T1 AT E211484T1
Authority
AT
Austria
Prior art keywords
cyclic peptide
peptide compounds
production method
pain treatment
narcotics
Prior art date
Application number
AT97309757T
Other languages
English (en)
Inventor
Hideo Hirai
Nakao Kojima
Hiroyuki Nishida
Toshiyuki Saito
Nobuji Yoshikawa
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE211484T1 publication Critical patent/ATE211484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Addiction (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97309757T 1996-12-04 1997-12-03 Zyklische peptideverbindungen zur schmerzbehandlung und ihr herstellungsverfahren ATE211484T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9601352 1996-12-04

Publications (1)

Publication Number Publication Date
ATE211484T1 true ATE211484T1 (de) 2002-01-15

Family

ID=11004499

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97309757T ATE211484T1 (de) 1996-12-04 1997-12-03 Zyklische peptideverbindungen zur schmerzbehandlung und ihr herstellungsverfahren

Country Status (10)

Country Link
US (1) US5885959A (de)
EP (1) EP0852232B1 (de)
JP (1) JP3521110B2 (de)
AT (1) ATE211484T1 (de)
BR (1) BR9706222A (de)
CA (1) CA2223360C (de)
DE (1) DE69709841T2 (de)
DK (1) DK0852232T3 (de)
ES (1) ES2169325T3 (de)
MX (1) MX9709494A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.
DK1633774T3 (da) * 2003-06-18 2010-05-25 Tranzyme Pharma Inc Makrocykliske motilinreceptorantagonister
WO2016007956A2 (en) * 2014-07-11 2016-01-14 University Of Kansas Cyclic tetrapeptide stereoisomers
CN110430889B (zh) * 2017-01-20 2023-09-19 堪萨斯大学 降低c-myc蛋白质水平并减慢癌细胞生长的大环肽
WO2019183556A1 (en) 2018-03-23 2019-09-26 University Of Kansas Cyclic tetrapeptide analogs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255224A3 (de) * 1986-06-30 1990-04-18 Merck & Co. Inc. Cyclische und verbrückt cyclische Analoge von Somatostatin, verwendbar als analgetische Arzneimittel
CA2090171A1 (en) * 1993-02-23 1994-08-24 Peter W. Schiller Opioid receptor antagonists, their synthesis and use as analgesic and immunosuppressive compounds
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists
IS4261A (is) * 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.

Also Published As

Publication number Publication date
DE69709841D1 (de) 2002-02-28
US5885959A (en) 1999-03-23
ES2169325T3 (es) 2002-07-01
EP0852232B1 (de) 2002-01-02
CA2223360C (en) 2000-05-30
DK0852232T3 (da) 2002-04-22
EP0852232A1 (de) 1998-07-08
CA2223360A1 (en) 1998-06-04
MX9709494A (es) 1998-07-31
JP3521110B2 (ja) 2004-04-19
JPH111492A (ja) 1999-01-06
DE69709841T2 (de) 2002-08-22
BR9706222A (pt) 1999-06-01

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Legal Events

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REN Ceased due to non-payment of the annual fee