IS4261A - Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra - Google Patents

Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra

Info

Publication number
IS4261A
IS4261A IS4261A IS4261A IS4261A IS 4261 A IS4261 A IS 4261A IS 4261 A IS4261 A IS 4261A IS 4261 A IS4261 A IS 4261A IS 4261 A IS4261 A IS 4261A
Authority
IS
Iceland
Prior art keywords
peptides
pain
treatment
opioid
compositions
Prior art date
Application number
IS4261A
Other languages
English (en)
Inventor
Brown William
Dimaio John
Schiller Peter
Martel René
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9403263A external-priority patent/GB9403263D0/en
Priority claimed from SE9401519A external-priority patent/SE9401519D0/xx
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of IS4261A publication Critical patent/IS4261A/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS4261A 1994-02-21 1995-02-13 Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra IS4261A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9403263A GB9403263D0 (en) 1994-02-21 1994-02-21 Novel opiod peptides
GB9408179A GB9408179D0 (en) 1994-02-21 1994-04-25 Novel opioid peptides for the treatment of pain and use thereof
SE9401519A SE9401519D0 (sv) 1994-05-03 1994-05-03 Novel opioid peptides for the tratment of pain and use thereof

Publications (1)

Publication Number Publication Date
IS4261A true IS4261A (is) 1995-08-22

Family

ID=27267061

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4261A IS4261A (is) 1994-02-21 1995-02-13 Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra

Country Status (20)

Country Link
EP (1) EP0746567B1 (is)
JP (1) JPH09509168A (is)
AT (1) ATE217011T1 (is)
BR (1) BR9506847A (is)
CA (1) CA2181367A1 (is)
CZ (1) CZ288523B6 (is)
DE (1) DE69526577T2 (is)
EE (1) EE03265B1 (is)
ES (1) ES2176322T3 (is)
FI (1) FI963252L (is)
HR (1) HRP950413A2 (is)
HU (1) HUT74731A (is)
IS (1) IS4261A (is)
MX (1) MX9603489A (is)
NO (1) NO963464L (is)
NZ (1) NZ281742A (is)
PL (1) PL181092B1 (is)
SK (1) SK93596A3 (is)
TW (1) TW408131B (is)
WO (1) WO1995022557A1 (is)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503924D0 (sv) * 1995-08-18 1995-11-07 Astra Ab Novel opioid peptides
DK0853484T3 (da) * 1995-06-07 2003-01-20 Torrey Pines Inst Hidtil ukendte MU-opioid-receptorligander: agonister og antagonister
GB9516994D0 (en) * 1995-08-18 1995-10-18 Iaf Biochem Int Solution synthesis of peripheral acting analgestic opioid tetrapeptides
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.
US5885958A (en) 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
AU4572999A (en) 1998-06-18 2000-01-05 Sepracor, Inc. Tetrapeptides, analogs and peptidomimetics which bind selectively mammalian opioid receptors
SE9900961D0 (sv) * 1999-03-16 1999-03-16 Astra Ab Novel compounds
AU2001239896A1 (en) 2000-03-16 2001-10-03 Sepracor, Inc. Peptidomimetic ligands for cellular receptors and ion channels
ATE496533T1 (de) 2000-07-18 2011-02-15 Cornell Res Foundation Inc Medizinische verwendung von agonisten des mu- opioid rezeptors
EP3479838A1 (en) 2003-02-04 2019-05-08 Cornell Research Foundation, Inc. Uses of aromatic-cationic peptide
WO2005072295A2 (en) 2004-01-23 2005-08-11 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
EP1625149B1 (en) 2003-05-01 2016-02-17 Cornell Research Foundation, Inc. Method and carrier complexes for delivering molecules to cells
EA200701852A1 (ru) 2005-04-28 2008-04-28 Пфайзер Лимитед Производные аминокислот
CN103784937B (zh) 2005-09-16 2017-04-26 科内尔研究基金会 用于减少cd36表达的方法
EP1782819A1 (en) 2005-11-03 2007-05-09 Cognis IP Management GmbH Oligopeptides and their use
JP5244810B2 (ja) 2006-11-10 2013-07-24 カラ セラピューティクス インコーポレイテッド 合成ペプチドアミド
US8236766B2 (en) 2006-11-10 2012-08-07 Cara Therapeutics, Inc. Uses of synthetic peptide amides
US7842662B2 (en) 2006-11-10 2010-11-30 Cara Therapeutics, Inc. Synthetic peptide amide dimers
US8906859B2 (en) 2006-11-10 2014-12-09 Cera Therapeutics, Inc. Uses of kappa opioid synthetic peptide amides
US7713937B2 (en) 2006-11-10 2010-05-11 Cara Therapeutics, Inc. Synthetic peptide amides and dimeric forms thereof
CN102127152B (zh) * 2007-06-11 2012-07-04 北京大学 一种抗阿片肽的拮抗肽与该拮抗肽的应用
CN102127151B (zh) * 2007-06-11 2012-07-04 北京大学 抗阿片肽的拮抗肽与该拮抗肽的应用
CN101817877B (zh) * 2007-06-28 2011-09-14 北京大学 一种抗阿片肽的活性片段
CN101805396B (zh) * 2007-06-28 2011-09-14 北京大学 抗阿片肽的拮抗肽与该拮抗肽的应用
JP5453320B2 (ja) 2008-02-07 2014-03-26 コーネル ユニヴァーシティー インスリン抵抗性を防止または処置するための方法
US8143219B2 (en) 2008-02-26 2012-03-27 Cornell University Methods for prevention and treatment of acute renal injury
US20210355166A1 (en) * 2018-05-31 2021-11-18 The University Of Sydney Analgesics and methods of use thereof
JP7437578B2 (ja) * 2019-03-20 2024-02-26 国立大学法人東北大学 新規オピオイドペプチド、その糖鎖付加体及びそれらを含む医薬組成物
CN113968902B (zh) * 2020-07-25 2023-05-26 兰州大学 亮氨酸-脑啡肽类似物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
CZ168194A3 (en) * 1992-11-12 1994-12-15 Biomeasure Opioid peptides
SE9300012D0 (sv) * 1993-01-05 1993-01-05 Astra Ab New peptides

Also Published As

Publication number Publication date
CZ288523B6 (cs) 2001-07-11
HRP950413A2 (en) 1997-10-31
PL315947A1 (en) 1996-12-09
BR9506847A (pt) 1997-09-30
NZ281742A (en) 1997-06-24
WO1995022557A1 (en) 1995-08-24
DE69526577D1 (de) 2002-06-06
TW408131B (en) 2000-10-11
FI963252A0 (fi) 1996-08-20
AU690648B2 (en) 1998-04-30
AU1865195A (en) 1995-09-04
ES2176322T3 (es) 2002-12-01
CZ239196A3 (en) 1996-12-11
DE69526577T2 (de) 2003-01-02
FI963252A7 (fi) 1996-08-20
HU9602281D0 (en) 1996-10-28
HUT74731A (en) 1997-02-28
FI963252L (fi) 1996-08-20
NO963464L (no) 1996-08-20
PL181092B1 (pl) 2001-05-31
CA2181367A1 (en) 1995-08-24
MX9603489A (es) 1997-03-29
EP0746567A1 (en) 1996-12-11
SK93596A3 (en) 1997-05-07
EE03265B1 (et) 2000-04-17
EP0746567B1 (en) 2002-05-02
ATE217011T1 (de) 2002-05-15
JPH09509168A (ja) 1997-09-16

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