ATE213168T1 - Technetium - 99m markierte peptide zur bildformung - Google Patents

Technetium - 99m markierte peptide zur bildformung

Info

Publication number: ATE213168T1
Authority: AT; Austria
Prior art keywords: peptides; technetium; somatostatin; radiolabeled; methods
Prior art date: 1991-11-27

Application number

AT93901469T

Other languages

English (en)

Inventor

Richard T Dean

William Mcbride

Scott Buttram

Original Assignee

Diatide Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-27

Filing date

1992-11-19

Publication date

2002-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25195476&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE213168(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-11-19 Application filed by Diatide Inc filed Critical Diatide Inc

2002-02-15 Application granted granted Critical

2002-02-15 Publication of ATE213168T1 publication Critical patent/ATE213168T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title abstract 2
229940056501 technetium 99m Drugs 0.000 title abstract 2
238000007493 shaping process Methods 0.000 title 1
102000001189 Cyclic Peptides Human genes 0.000 abstract 3
108010069514 Cyclic Peptides Proteins 0.000 abstract 3
239000003153 chemical reaction reagent Substances 0.000 abstract 3
238000000034 method Methods 0.000 abstract 3
230000003439 radiotherapeutic effect Effects 0.000 abstract 3
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 3
WUAPFZMCVAUBPE-NJFSPNSNSA-N 188Re Chemical compound [188Re] WUAPFZMCVAUBPE-NJFSPNSNSA-N 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
238000000163 radioactive labelling Methods 0.000 abstract 2
WUAPFZMCVAUBPE-IGMARMGPSA-N rhenium-186 Chemical compound [186Re] WUAPFZMCVAUBPE-IGMARMGPSA-N 0.000 abstract 2
102000005157 Somatostatin Human genes 0.000 abstract 1
108010056088 Somatostatin Proteins 0.000 abstract 1
231100000433 cytotoxic Toxicity 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
239000012216 imaging agent Substances 0.000 abstract 1
229960000553 somatostatin Drugs 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/28—Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

AT93901469T 1991-11-27 1992-11-19 Technetium - 99m markierte peptide zur bildformung ATE213168T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/807,062 US5443815A (en)	1991-11-27	1991-11-27	Technetium-99m labeled peptides for imaging
PCT/US1992/010716 WO1993010747A2 (en)	1991-11-27	1992-11-19	TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING

Publications (1)

Publication Number	Publication Date
ATE213168T1 true ATE213168T1 (de)	2002-02-15

Family

ID=25195476

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93901469T ATE213168T1 (de)	1991-11-27	1992-11-19	Technetium - 99m markierte peptide zur bildformung

Country Status (10)

Country	Link
US (5)	US5443815A (de)
EP (1)	EP0614379B1 (de)
JP (1)	JP3036602B2 (de)
AT (1)	ATE213168T1 (de)
AU (2)	AU3276093A (de)
CA (1)	CA2124458C (de)
DE (1)	DE69232418T2 (de)
DK (1)	DK0614379T3 (de)
ES (1)	ES2172513T3 (de)
WO (1)	WO1993010747A2 (de)

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1991
- 1991-11-27 US US07/807,062 patent/US5443815A/en not_active Expired - Lifetime
1992
- 1992-11-19 DK DK93901469T patent/DK0614379T3/da active
- 1992-11-19 US US08/244,336 patent/US5866097A/en not_active Expired - Fee Related
- 1992-11-19 EP EP93901469A patent/EP0614379B1/de not_active Revoked
- 1992-11-19 ES ES93901469T patent/ES2172513T3/es not_active Expired - Lifetime
- 1992-11-19 AU AU32760/93A patent/AU3276093A/en not_active Abandoned
- 1992-11-19 CA CA002124458A patent/CA2124458C/en not_active Expired - Fee Related
- 1992-11-19 AT AT93901469T patent/ATE213168T1/de not_active IP Right Cessation
- 1992-11-19 WO PCT/US1992/010716 patent/WO1993010747A2/en not_active Ceased
- 1992-11-19 JP JP05510399A patent/JP3036602B2/ja not_active Expired - Fee Related
- 1992-11-19 DE DE69232418T patent/DE69232418T2/de not_active Expired - Fee Related
1993
- 1993-07-15 US US08/092,355 patent/US6017509A/en not_active Expired - Fee Related
1995
- 1995-06-05 US US08/462,212 patent/US5807537A/en not_active Expired - Fee Related
- 1995-06-06 US US08/471,741 patent/US5814297A/en not_active Expired - Fee Related
1997
- 1997-08-13 AU AU34151/97A patent/AU721198B2/en not_active Ceased

Also Published As

Publication number	Publication date
US5443815A (en)	1995-08-22
EP0614379A1 (de)	1994-09-14
US5866097A (en)	1999-02-02
AU3276093A (en)	1993-06-28
US5807537A (en)	1998-09-15
US5814297A (en)	1998-09-29
WO1993010747A3 (en)	1994-03-03
DK0614379T3 (da)	2002-05-13
JP3036602B2 (ja)	2000-04-24
AU3415197A (en)	1997-11-06
EP0614379B1 (de)	2002-02-13
WO1993010747A2 (en)	1993-06-10
DE69232418D1 (de)	2002-03-21
AU721198B2 (en)	2000-06-29
CA2124458C (en)	2001-01-30
ES2172513T3 (es)	2002-10-01
DE69232418T2 (de)	2002-10-31
CA2124458A1 (en)	1993-06-10
JPH07506086A (ja)	1995-07-06
US6017509A (en)	2000-01-25

Legal Events

Date	Code	Title
2003-01-15	UEP	Publication of translation of european patent specification
2010-08-15	REN	Ceased due to non-payment of the annual fee
2010-09-15	RZN	Patent revoked

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DK0804481T3 (da)	2003-07-28	Somatostatin-derivater og deres radioaktivt mærkede produkter
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MX9707426A (es)	1998-07-31	Peptidos marcados radioactivamente para diagnostico y terapia.
DK0649434T3 (da)	2001-11-12	Radioaktivt mærkede somatostatin-afledte peptider til billeddannende og terapeutiske anvendelser
JP3918157B2 (ja)	2007-05-23	ソマトスタチン結合性ペプチド−金属キレートコンジュゲート
ATE237365T1 (de)	2003-05-15	Technetium-99-markierte peptide zur visualisierung vom entzuendungen
ZA956254B (en)	1996-03-13	Peptides
HUP0001477A2 (hu)	2000-09-28	Kalcitonin receptorhoz kötődő peptidek
CA2347670A1 (en)	1995-01-05	Radiolabeled somatostatin-derived peptides for imaging
JPH08231587A (ja)	1996-09-10	金属キレート形成性ペプチド、その用途及びその製造方法