ATE213941T1 - Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate - Google Patents

Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate

Info

Publication number: ATE213941T1
Authority: AT; Austria
Prior art keywords: derivatives; preparations containing; topical preparations; effective amount; containing benzimidazole
Prior art date: 1988-11-29

Application number

AT94200665T

Other languages

English (en)

Inventor

Wauwe Jean Pierre Frans Van

Alfons Herman Marg Raeymaekers

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-29

Filing date

1989-11-27

Publication date

2002-03-15

1989-11-27 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2002-03-15 Application granted granted Critical

2002-03-15 Publication of ATE213941T1 publication Critical patent/ATE213941T1/de

Links

229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
150000001556 benzimidazoles Chemical class 0.000 title 1
150000001565 benzotriazoles Chemical class 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
230000000699 topical effect Effects 0.000 title 1
230000002159 abnormal effect Effects 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
210000002919 epithelial cell Anatomy 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000001613 neoplastic effect Effects 0.000 abstract 1
230000001855 preneoplastic effect Effects 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
229930002330 retinoic acid Natural products 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229960001727 tretinoin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Birds (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Dermatology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)

AT94200665T 1988-11-29 1989-11-27 Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate ATE213941T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27715288A	1988-11-29	1988-11-29

Publications (1)

Publication Number	Publication Date
ATE213941T1 true ATE213941T1 (de)	2002-03-15

Family

ID=23059616

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT89203001T ATE112681T1 (de)	1988-11-29	1989-11-27	Verwendung von benzimidazol-derivaten bei der behandlung von epithelialen erkrankungen.
AT94200665T ATE213941T1 (de)	1988-11-29	1989-11-27	Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT89203001T ATE112681T1 (de)	1988-11-29	1989-11-27	Verwendung von benzimidazol-derivaten bei der behandlung von epithelialen erkrankungen.

Country Status (16)

Country	Link
EP (2)	EP0371559B1 (de)
JP (2)	JP2752200B2 (de)
AT (2)	ATE112681T1 (de)
AU (2)	AU623454B2 (de)
CA (1)	CA2002859C (de)
CY (1)	CY1867A (de)
DE (2)	DE68929377T2 (de)
DK (1)	DK175793B1 (de)
ES (2)	ES2173902T3 (de)
HK (1)	HK114895A (de)
IE (1)	IE63877B1 (de)
IL (1)	IL92487A (de)
NZ (1)	NZ231405A (de)
PT (1)	PT92449B (de)
SG (1)	SG50466A1 (de)
ZA (1)	ZA899074B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2002859C (en) *	1988-11-29	1998-12-29	Jean P. F. Van Wauwe	Method of treating epithelial disorders
FI952251A7 (fi) *	1992-11-10	1995-05-09	Janssen Pharmaceutica Nv	Menetelmä enantiomeerisesti puhtaan 6-((4-kloorifenyyli)-(1H-triatsoli -1,2,4-triatsol-1-yyli)metyyli)-1-metyyli-1H-bentsotriatsolin valmista miseksi
US5484612A (en) *	1993-09-22	1996-01-16	The Board Of Trustees Of The Leland Stanford Junior University	Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
SG52325A1 (en) *	1994-02-18	1998-09-28	Janssen Pharmaceutica Nv	Enantiomerically pure(+)-liarozole
AU688852B2 (en) *	1994-02-18	1998-03-19	Janssen Pharmaceutica N.V.	Enantiomerically pure(-)-liarozole
TW316902B (de) *	1994-12-28	1997-10-01	Janssen Pharmaceutica Nv
WO1996019991A1 (en) *	1994-12-28	1996-07-04	Janssen Pharmaceutica N.V.	Benzimidazoles as inhibitors of calcitriol metabolism
US5536740A (en) *	1995-06-01	1996-07-16	Elizabeth Arden Company, Division Of Conopco, Inc.	Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester
WO1997006788A1 (en) *	1995-08-14	1997-02-27	Janssen Pharmaceutica N.V.	Transdermal administration of vorozole
TW349948B (en) *	1995-10-31	1999-01-11	Janssen Pharmaceutica Nv	Farnesyl transferase inhibiting 2-quinolone derivatives
US5716627A (en) *	1996-04-25	1998-02-10	Elizabeth Arden Co., Division Of Conopco, Inc.	Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
SK282769B6 (sk) *	1996-06-27	2002-12-03	Janssen Pharmaceutica N. V.	N-[4-(Heteroarylmetyl)fenyl]heteroarylamín, spôsob jeho výroby a použitia, kompozícia na jeho báze
JPH10220909A (ja)	1996-12-03	1998-08-21	Komatsu Ltd	流体温度制御装置
TW591030B (en) *	1997-03-10	2004-06-11	Janssen Pharmaceutica Nv	Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
TR200001645T2 (tr)	1997-12-11	2000-12-21	Janssen Pharmaceutica N.V.	Retinoyik asit taklidi anilürler.
US6420555B1 (en)	1998-06-16	2002-07-16	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Imidazolyl derivatives
CA2335435A1 (en) *	1998-06-16	1999-12-23	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Imidazolyl derivatives
WO2000066077A1 (en) *	1999-04-29	2000-11-09	Avon Products, Inc.	Method of improving the aesthetic appearance of epithelia
EP1420015A1 (de) *	1999-06-11	2004-05-19	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Imidazol-Derivate
FR2815857B1 (fr) *	2000-10-30	2003-02-14	Oreal	Composition, notamment cosmetique, renfermant un retinoide et une silicone benzotriazole
US7405235B2 (en)	2001-05-04	2008-07-29	Paratek Pharmaceuticals, Inc.	Transcription factor modulating compounds and methods of use thereof
JP2006513162A (ja) *	2002-11-01	2006-04-20	パラテックファーマシューティカルズインコーポレイテッド	転写因子調節化合物およびその使用方法
AU2005324492B2 (en)	2004-04-23	2012-06-07	Paratek Pharmaceuticals, Inc.	Transcription factor modulating compounds and methods of use thereof
MX2012007367A (es)	2009-12-30	2013-04-03	Arqule Inc	Compuestos substituidos de imidazopiridinilo-aminopiridina.
KR101974673B1 (ko)	2011-06-24	2019-05-02	아르퀼 인코포레이티드	치환된 이미다조피리디닐-아미노피리딘 화합물
WO2012177852A1 (en)	2011-06-24	2012-12-27	Arqule, Inc	Substituted imidazopyridinyl compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ221729A (en) *	1986-09-15	1989-07-27	Janssen Pharmaceutica Nv	Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
US4859684A (en) *	1986-09-15	1989-08-22	Janssen Pharmaceutica N.V.	(1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
NZ224714A (en) *	1987-06-01	1990-03-27	Janssen Pharmaceutica Nv	Substituted benzotriazole derivatives and pharmaceutical compositions
CA2002859C (en) *	1988-11-29	1998-12-29	Jean P. F. Van Wauwe	Method of treating epithelial disorders

1989
- 1989-11-14 CA CA002002859A patent/CA2002859C/en not_active Expired - Lifetime
- 1989-11-15 NZ NZ231405A patent/NZ231405A/xx unknown
- 1989-11-27 ES ES94200665T patent/ES2173902T3/es not_active Expired - Lifetime
- 1989-11-27 ES ES89203001T patent/ES2065369T3/es not_active Expired - Lifetime
- 1989-11-27 AT AT89203001T patent/ATE112681T1/de not_active IP Right Cessation
- 1989-11-27 EP EP89203001A patent/EP0371559B1/de not_active Expired - Lifetime
- 1989-11-27 SG SG1996002122A patent/SG50466A1/en unknown
- 1989-11-27 DE DE68929377T patent/DE68929377T2/de not_active Expired - Lifetime
- 1989-11-27 DE DE68918809T patent/DE68918809T2/de not_active Expired - Lifetime
- 1989-11-27 EP EP94200665A patent/EP0609963B1/de not_active Expired - Lifetime
- 1989-11-27 AT AT94200665T patent/ATE213941T1/de not_active IP Right Cessation
- 1989-11-28 IE IE378189A patent/IE63877B1/en not_active IP Right Cessation
- 1989-11-28 DK DK198905995A patent/DK175793B1/da not_active IP Right Cessation
- 1989-11-28 ZA ZA899074A patent/ZA899074B/xx unknown
- 1989-11-28 AU AU45648/89A patent/AU623454B2/en not_active Expired
- 1989-11-28 IL IL9248789A patent/IL92487A/en not_active IP Right Cessation
- 1989-11-29 PT PT92449A patent/PT92449B/pt not_active IP Right Cessation
- 1989-11-29 JP JP1307792A patent/JP2752200B2/ja not_active Expired - Lifetime
1992
- 1992-01-31 AU AU10716/92A patent/AU630579B2/en not_active Expired
1995
- 1995-07-13 HK HK114895A patent/HK114895A/en not_active IP Right Cessation
1996
- 1996-04-05 CY CY186796A patent/CY1867A/xx unknown
1997
- 1997-05-13 JP JP9137444A patent/JP2912596B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SG50466A1 (en)	1998-07-20
ATE112681T1 (de)	1994-10-15
IL92487A0 (en)	1990-08-31
NZ231405A (en)	1991-08-27
IE950033L (en)	1990-05-29
ES2065369T3 (es)	1995-02-16
AU623454B2 (en)	1992-05-14
EP0371559A2 (de)	1990-06-06
EP0609963A1 (de)	1994-08-10
EP0371559A3 (de)	1992-04-08
EP0371559B1 (de)	1994-10-12
DK599589A (da)	1990-05-30
JP2752200B2 (ja)	1998-05-18
DK175793B1 (da)	2005-02-21
CA2002859A1 (en)	1990-05-29
HK114895A (en)	1995-07-21
ES2173902T3 (es)	2002-11-01
JPH1095782A (ja)	1998-04-14
IE893781L (en)	1990-05-29
DE68929377T2 (de)	2002-10-31
AU4564889A (en)	1990-06-07
AU630579B2 (en)	1992-10-29
EP0609963B1 (de)	2002-03-06
AU1071692A (en)	1992-03-19
JPH0320273A (ja)	1991-01-29
CY1867A (en)	1996-04-05
CA2002859C (en)	1998-12-29
IL92487A (en)	1994-12-29
DK599589D0 (da)	1989-11-28
ZA899074B (en)	1991-07-31
JP2912596B2 (ja)	1999-06-28
DE68929377D1 (de)	2002-04-11
PT92449A (pt)	1990-05-31
PT92449B (pt)	1995-07-18
DE68918809D1 (de)	1994-11-17
IE63877B1 (en)	1995-06-14
DE68918809T2 (de)	1995-03-23

Legal Events

Date	Code	Title	Description
2003-01-15	UEP	Publication of translation of european patent specification
2010-02-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE213941T1 (de)	2002-03-15	Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate
NO180719C (no)	1997-06-04	Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater
ES2088889T3 (es)	1996-10-01	Derivados de quinolina (1h-azol-1-ilmetil) sustituida, quinazolina o quinoxalina.
SE8804036D0 (sv)	1988-11-08	New use of 11,28-dioxa-4-azatricyclo(22.3.1.0?724,9 )octacos-18-ene derivatives and pharmaceutical compositions containing them
AU7949887A (en)	1988-04-28	Benzimidazole derivatives
ES8707947A1 (es)	1987-09-01	Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos.
NO173444C (no)	1993-12-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive 4-(4'- fluorfenyl-)-tienopyridin-derivater
ATE242220T1 (de)	2003-06-15	Benzimidazolderivate mit dopaminerger wirkung
ES2001703A6 (es)	1988-06-01	Procedimiento para la preparracion de derrrivados de acidos 2-(2-imidazolin -2-il)- piridin -3- carboxilicos.
EP0050286A3 (en)	1982-05-26	Novel pharmaceutical guanidine derivatives
DE3674546D1 (de)	1990-10-31	Amidderivate.
ATE73330T1 (de)	1992-03-15	Verwendung von pharmaceutischen zusammensetzungen fuer die herstellung von arzneimitteln fuer die behandlung psychiatrischer stoerungen.
ATE167869T1 (de)	1998-07-15	Thiolderivate von gallensäure
ES8300747A1 (es)	1982-11-01	Procedimiento para la preparacion de derivados de acido in- dolacetico
IT1247508B (it)	1994-12-17	Composizioni farmaceutiche contenenti l'estere 4-(2 metilamminoetil)- 1,2- fenilenicodell`acido 2-metilpropanoico per il trattamento della neurootticopatia glaucomatosa
DE68903188D1 (de)	1992-11-19	Acylsulfonamid-derivate von alpha-carbocyclyltoluylsaeuren und ihre verwendung als leukotrienantagonisten.
HUT40067A (en)	1986-11-28	Process for producing benzoic acid derivatives and pharmaceutical compositions containing them as active agents