ATE213951T1 - Cyclosporin enthaltende, biologisch aktive zubereitung - Google Patents

Cyclosporin enthaltende, biologisch aktive zubereitung

Info

Publication number: ATE213951T1
Authority: AT; Austria
Prior art keywords: biologically active; phase; preparation containing; cyclosporine; active preparation
Prior art date: 1995-07-06

Application number

AT96923154T

Other languages

English (en)

Inventor

Kare Larsson

Helena Ljusberg-Wahren

Original Assignee

Camurus Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-06

Filing date

1996-07-02

Publication date

2002-03-15

1996-07-02 Application filed by Camurus Ab filed Critical Camurus Ab

2002-03-15 Application granted granted Critical

2002-03-15 Publication of ATE213951T1 publication Critical patent/ATE213951T1/de

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 4
108010036949 Cyclosporine Proteins 0.000 title abstract 4
229960001265 ciclosporin Drugs 0.000 title abstract 4
229930182912 cyclosporin Natural products 0.000 title abstract 4
229930105110 Cyclosporin A Natural products 0.000 title 1
LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
229940088623 biologically active substance Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
229940125721 immunosuppressive agent Drugs 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Transplantation (AREA)
Dispersion Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Air-Conditioning For Vehicles (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96923154T 1995-07-06 1996-07-02 Cyclosporin enthaltende, biologisch aktive zubereitung ATE213951T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9502472A SE504582C2 (sv)	1995-07-06	1995-07-06	Cyklosporinkomposition baserad på en L2-fas
PCT/SE1996/000893 WO1997002042A1 (en)	1995-07-06	1996-07-02	Biologically active composition comprising cyclosporine

Publications (1)

Publication Number	Publication Date
ATE213951T1 true ATE213951T1 (de)	2002-03-15

Family

ID=20398887

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96923154T ATE213951T1 (de)	1995-07-06	1996-07-02	Cyclosporin enthaltende, biologisch aktive zubereitung

Country Status (12)

Country	Link
EP (1)	EP0873133B1 (de)
JP (1)	JPH11508592A (de)
AT (1)	ATE213951T1 (de)
AU (1)	AU6374596A (de)
BR (1)	BR9609332A (de)
CA (1)	CA2226219A1 (de)
CZ (1)	CZ1998A3 (de)
DE (2)	DE873133T1 (de)
ES (1)	ES2123477T3 (de)
NO (1)	NO980032L (de)
SE (1)	SE504582C2 (de)
WO (1)	WO1997002042A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE511313C2 (sv)	1997-01-13	1999-09-06	Gs Dev Ab	Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
WO1999029316A1 (en)	1997-12-10	1999-06-17	Severson, Mary, L.	Pharmaceutical compositions containing an omega-3 fatty acid oil
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
US6638522B1 (en) *	1998-12-11	2003-10-28	Pharmasolutions, Inc.	Microemulsion concentrate composition of cyclosporin
DE60221287D1 (de)	2001-11-08	2007-08-30	Atrium Medical Corp	Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung
US9801982B2 (en)	2004-09-28	2017-10-31	Atrium Medical Corporation	Implantable barrier device
US9000040B2 (en)	2004-09-28	2015-04-07	Atrium Medical Corporation	Cross-linked fatty acid-based biomaterials
US8367099B2 (en)	2004-09-28	2013-02-05	Atrium Medical Corporation	Perforated fatty acid films
US9012506B2 (en)	2004-09-28	2015-04-21	Atrium Medical Corporation	Cross-linked fatty acid-based biomaterials
EP1811935B1 (de)	2004-09-28	2016-03-30	Atrium Medical Corporation	Wärmegehärtetes gel und herstellungsverfahren
US9592324B2 (en)	2006-11-06	2017-03-14	Atrium Medical Corporation	Tissue separating device with reinforced support for anchoring mechanisms
US8312836B2 (en)	2004-09-28	2012-11-20	Atrium Medical Corporation	Method and apparatus for application of a fresh coating on a medical device
US20060067977A1 (en)	2004-09-28	2006-03-30	Atrium Medical Corporation	Pre-dried drug delivery coating for use with a stent
US9278161B2 (en)	2005-09-28	2016-03-08	Atrium Medical Corporation	Tissue-separating fatty acid adhesion barrier
US9427423B2 (en)	2009-03-10	2016-08-30	Atrium Medical Corporation	Fatty-acid based particles
AU2006304590A1 (en)	2005-10-15	2007-04-26	Atrium Medical Corporation	Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US9492596B2 (en)	2006-11-06	2016-11-15	Atrium Medical Corporation	Barrier layer with underlying medical device and one or more reinforcing support structures
ES2393814T3 (es)	2007-04-04	2012-12-28	Sigmoid Pharma Limited	Una composición farmacéutica oral
ES2530049T3 (es)	2009-05-18	2015-02-26	Sigmoid Pharma Limited	Composición que comprende gotas de aceite
US20110038910A1 (en)	2009-08-11	2011-02-17	Atrium Medical Corporation	Anti-infective antimicrobial-containing biomaterials
CN102573802A (zh)	2009-08-12	2012-07-11	希格默伊德药业有限公司	包含聚合物基质和油相的免疫调节组合物
US10322213B2 (en)	2010-07-16	2019-06-18	Atrium Medical Corporation	Compositions and methods for altering the rate of hydrolysis of cured oil-based materials
GB201020032D0 (en)	2010-11-25	2011-01-12	Sigmoid Pharma Ltd	Composition
JO3337B1 (ar) *	2010-12-13	2019-03-13	Debiopharm Sa	تركيبات صيدلية تشمل أليسبوريفير
US9867880B2 (en)	2012-06-13	2018-01-16	Atrium Medical Corporation	Cured oil-hydrogel biomaterial compositions for controlled drug delivery
GB201304662D0 (en)	2013-03-14	2013-05-01	Sigmoid Pharma Ltd	Compositions
JP6716582B2 (ja) *	2014-11-07	2020-07-01	サブリミティ・セラピューティクス・リミテッドＳｕｂｌｉｍｉｔｙＴｈｅｒａｐｅｕｔｉｃｓＬｉｍｉｔｅｄ	シクロスポリンを含む組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2907460A1 (de) *	1978-03-07	1979-09-13	Sandoz Ag	Neue resorbierbare galenische kompositionen
SE457693B (sv) *	1986-07-01	1989-01-23	Drilletten Ab	Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds

1995
- 1995-07-06 SE SE9502472A patent/SE504582C2/sv not_active IP Right Cessation
1996
- 1996-07-02 EP EP96923154A patent/EP0873133B1/de not_active Expired - Lifetime
- 1996-07-02 CA CA002226219A patent/CA2226219A1/en not_active Abandoned
- 1996-07-02 ES ES96923154T patent/ES2123477T3/es not_active Expired - Lifetime
- 1996-07-02 DE DE0873133T patent/DE873133T1/de active Pending
- 1996-07-02 WO PCT/SE1996/000893 patent/WO1997002042A1/en not_active Ceased
- 1996-07-02 CZ CZ9819A patent/CZ1998A3/cs unknown
- 1996-07-02 BR BR9609332A patent/BR9609332A/pt not_active Application Discontinuation
- 1996-07-02 AU AU63745/96A patent/AU6374596A/en not_active Abandoned
- 1996-07-02 DE DE69619700T patent/DE69619700T2/de not_active Expired - Fee Related
- 1996-07-02 JP JP9505078A patent/JPH11508592A/ja active Pending
- 1996-07-02 AT AT96923154T patent/ATE213951T1/de not_active IP Right Cessation
1998
- 1998-01-05 NO NO980032A patent/NO980032L/no unknown

Also Published As

Publication number	Publication date
CZ1998A3 (cs)	1998-06-17
JPH11508592A (ja)	1999-07-27
AU6374596A (en)	1997-02-05
DE873133T1 (de)	1999-05-06
NO980032L (no)	1998-03-03
NO980032D0 (no)	1998-01-05
SE9502472L (sv)	1997-01-07
CA2226219A1 (en)	1997-01-23
SE9502472D0 (sv)	1995-07-06
BR9609332A (pt)	1999-05-25
EP0873133A1 (de)	1998-10-28
DE69619700T2 (de)	2002-10-24
ES2123477T1 (es)	1999-01-16
EP0873133B1 (de)	2002-03-06
DE69619700D1 (de)	2002-04-11
WO1997002042A1 (en)	1997-01-23
SE504582C2 (sv)	1997-03-10
ES2123477T3 (es)	2002-08-01

Legal Events

Date	Code	Title	Description
2002-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69619700D1 (de)	2002-04-11	Cyclosporin enthaltende, biologisch aktive zubereitung
Stellato et al.	1992	Anti-inflammatory effect of cyclosporin A on human skin mast cells
NZ504076A (en)	2002-12-20	A topical formulation which induces a minimal systemic effect when applied to the skin, the topical formulation comprising an immunosuppressive macrolide selected from sirolimus, FK506 and SDZ ASM 981 and a permeation modulator for the treatment of a dermatological condition
CA2221096A1 (en)	1996-12-19	Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate
ES2088160T3 (es)	1996-08-01	Formulacion y proceso quimicos.
CA2283280A1 (en)	1999-02-25	Reovirus for the treatment of neoplasia
NO975218D0 (no)	1997-11-13	Behandling av inflammatorisk tarmsykdom ved bruk av orale doseringsformer av omega-3-polyumettede syrer
EP0983994A3 (de)	2001-01-10	Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
KR860000865A (ko)	1986-02-20	약제 제형의 제조방법
IL122401A0 (en)	1998-06-15	Anti-inflammatory compositions
NO20035434D0 (no)	2003-12-05	Behandling eller profylakse av transplantasjonsavst degree tning av insulinproduserende celler
EP0255028A3 (de)	1990-03-21	Neue 1,4-Benzodiazepine, ihre Herstellung und Verwendung als PAF Antagonisten
YU49404B (sh)	2005-11-28	Nova smesa koja sadrži ciklosporin i poboljšani postupak za dobijanje mekih želatinskih kapsula koje sadrže ciklosporin
WO1997000671A3 (de)	1997-02-13	Zusammensetzung zur herstellung feindisperser systeme und verfahren zu ihrer herstellung
IE36563B1 (en)	1976-12-08	New diazepine derivatives and processes for their production
EA200100366A1 (ru)	2001-08-27	Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии
JPS5354866A (en)	1978-05-18	Method of treating sewege
WO1998029131A3 (en)	1998-10-01	Aqueous glycerol formulations of somatotropin
JPS52125629A (en)	1977-10-21	Deodorant made from spent sludge from microbial waste-water treatment and method of making the same
JPS5668619A (en)	1981-06-09	Nifedipine-containing solid composition
JPS54126722A (en)	1979-10-02	Slow release antibiotic tablet
JPS52151732A (en)	1977-12-16	Prophylactic and therapeutic agent against bacterial
Mori et al.	1965	Histochemical detection of three dehydrogenase systems in ameloblastoma
JPS52145592A (en)	1977-12-03	Immobilization of enzymes of microbial cells
JPS5257390A (en)	1977-05-11	Immobilized enzyme and method of preparing the same