ATE213952T1 - Freisetzung und mobilisierung hämatopoietischer zellen - Google Patents

Freisetzung und mobilisierung hämatopoietischer zellen

Info

Publication number
ATE213952T1
ATE213952T1 AT94918421T AT94918421T ATE213952T1 AT E213952 T1 ATE213952 T1 AT E213952T1 AT 94918421 T AT94918421 T AT 94918421T AT 94918421 T AT94918421 T AT 94918421T AT E213952 T1 ATE213952 T1 AT E213952T1
Authority
AT
Austria
Prior art keywords
pct
1alpha
mobilization
release
sec
Prior art date
Application number
AT94918421T
Other languages
English (en)
Inventor
Michael Berisford Comer
Matthew John Mccourt
Lars Michael Wood
Michael George Hunter
Richard Mark Edwards
Andrew John Hubert Gearing
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939312343A external-priority patent/GB9312343D0/en
Priority claimed from GB939324252A external-priority patent/GB9324252D0/en
Priority claimed from GB9402188A external-priority patent/GB9402188D0/en
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Application granted granted Critical
Publication of ATE213952T1 publication Critical patent/ATE213952T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT94918421T 1993-06-15 1994-06-15 Freisetzung und mobilisierung hämatopoietischer zellen ATE213952T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB939312343A GB9312343D0 (en) 1993-06-15 1993-06-15 Pharmaceutical use
GB939324252A GB9324252D0 (en) 1993-11-25 1993-11-25 Pharmaceutical use
GB9402188A GB9402188D0 (en) 1994-02-04 1994-02-04 Pharmaceutical use
PCT/GB1994/001284 WO1994028916A1 (en) 1993-06-15 1994-06-15 Release and mobilisation of haematopoietic cells

Publications (1)

Publication Number Publication Date
ATE213952T1 true ATE213952T1 (de) 2002-03-15

Family

ID=27266724

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94918421T ATE213952T1 (de) 1993-06-15 1994-06-15 Freisetzung und mobilisierung hämatopoietischer zellen

Country Status (8)

Country Link
US (1) US5925568A (de)
EP (1) EP0703784B1 (de)
JP (1) JPH08511263A (de)
AT (1) ATE213952T1 (de)
AU (1) AU6974294A (de)
DE (1) DE69430059T2 (de)
ES (1) ES2172536T3 (de)
WO (1) WO1994028916A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2210255T3 (es) 1993-06-08 2004-07-01 Smithkline Beecham Corporation Metodos para mejorar la actividad biologica de quimiocinas.
US6447766B1 (en) 1993-06-08 2002-09-10 Smithkline Beecham Corporation Method of mobilizing hematopoietic stem cells
US5595973A (en) * 1994-09-12 1997-01-21 Biomeasure Incorporated Protection of hemopoietic cells during chemotherapy or radiotherapy
GB9426012D0 (en) * 1994-12-22 1995-02-22 British Biotech Pharm Mobilisation of haematopoietic cells
US6713052B1 (en) 1995-10-24 2004-03-30 Human Genome Sciences, Inc. Method of mobilizing stem cells with chemokine β-8
GB9600559D0 (en) * 1996-01-11 1996-03-13 British Biotech Pharm Use of chemokines
EP0848012A1 (de) * 1996-12-13 1998-06-17 Roche Diagnostics GmbH Verwendung von Polypeptiden zur Behandlung von Thrombozytopenien
US6919318B1 (en) 1998-04-22 2005-07-19 Chiron Corporation Enhancing immune responses to genetic immunization by using a chemokine
EP1073749B1 (de) * 1998-04-22 2006-01-11 Chiron Corporation Erhöhung der immunantworten bei genetischer immunisierung durch verwendung eines chemokins
PT1016414E (pt) 1998-12-17 2004-12-31 Applied Research Systems Hormona de crescimento humano para estimular a hematopoiese e a reconstituicao imnologica apos transplante de celulas estaminais hematopoieticas em humanos
EP1016413A1 (de) * 1998-12-30 2000-07-05 Applied Research Systems ARS Holding N.V. Menschliches Wachstumshormon (HGH) zur Stimulierung der Mobilisierung pluripotenter Hämatopoietischer Stammzellen
US9694038B2 (en) 2000-04-06 2017-07-04 Wayne P. Franco Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs
US10281478B2 (en) 2000-04-06 2019-05-07 Wayne P. Franco Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs
US7361329B2 (en) 2000-04-21 2008-04-22 Chemocentryx, Inc. Compositions for inducing an immune response
US20040115175A1 (en) * 2000-11-10 2004-06-17 The Board Of Trustees Of The Leland Methods for treating disorders of neuronal deficiency with bone marrow-derived cells
AU2002219830A1 (en) * 2000-11-10 2002-05-21 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating disorders of neuronal deficiency with bone marrow-derived cells
US7247297B2 (en) * 2001-09-14 2007-07-24 The University Of Chicago Use of DF3/MUC1 regulated expression in gene therapy
WO2003035106A1 (en) * 2001-10-24 2003-05-01 Chemocentryx Methods and compositions for inducing an immune response by co-administering a chemokine with an antigen
JP2004196770A (ja) * 2002-10-24 2004-07-15 Effector Cell Institute Inc 樹状細胞前駆体の血中レベル上昇剤
AU2005326226B2 (en) * 2005-01-31 2010-11-11 Eci, Inc. Immunopotentiating agent
WO2009024426A1 (en) * 2007-07-27 2009-02-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Immunizing compositions for inducing 'bystander' killing of pathogens
US8846559B2 (en) * 2008-11-03 2014-09-30 Saudi Basic Industries Corporation Stable shape-selective catalyst for aromatic alkylation and methods of using and preparing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809419D0 (en) * 1988-04-21 1988-05-25 Pragnell I Stem cell inhibitors
DE69020573T3 (de) * 1989-09-25 1999-12-16 Crc Technology Ltd., London Verfahren zur wachstumshemmung von stammzellen.

Also Published As

Publication number Publication date
EP0703784B1 (de) 2002-03-06
AU6974294A (en) 1995-01-03
JPH08511263A (ja) 1996-11-26
DE69430059D1 (de) 2002-04-11
ES2172536T3 (es) 2002-10-01
EP0703784A1 (de) 1996-04-03
DE69430059T2 (de) 2002-11-14
WO1994028916A1 (en) 1994-12-22
US5925568A (en) 1999-07-20

Similar Documents

Publication Publication Date Title
DE69430059D1 (de) Freisetzung und Mobilisierung hämatopoietischer Zellen
NO20001583D0 (no) Stimulering av hematopoetiske celler in vitro
ES2154741T3 (es) Uso de agentes de union a cd23 en el tratamiento de enfermedades autoinmunes.
DK1131410T3 (da) Gensplejsede vævskonstruktioner og fremgangsmåde til fremstilling og anvendelse deraf
FI935585A0 (fi) Pyrrolopyrimidiner
ATE265220T1 (de) Kostimulatorische blockade und gemischter chimerismus in allotransplantationen
TR200002616T2 (tr) Simetrik ve simetrik olmayan sübstitüe edilmiş difenil üreler kullanılarak raf kinazın inhibe edilmesi
DK0751959T3 (da) Modificerede polypeptider med forøget biologisk aktivitet
ES2109945T3 (es) Composiciones y procedimientos para identificar moleculas biologicamente activas.
ATE169445T1 (de) Verwendung von gelformulierungen als beizmittel
ID22801A (id) Bakteri pelapor bioluminesense dan metode-metode untuk memonitor toksisitas dalam sistim-sistim pengolahan secara biologis
ATE514771T1 (de) Haartransplantation
FI893681A0 (fi) N-2,3-butadienyltri- och tetra-aminoalkanderivat.
TR199802704T2 (xx) H�V tedavisinde Vx478, Zidov�din, FTC ve/veya 3TC i�eren kombinasyonlar�n kullan�m�.
TR200001486T2 (tr) Hiperkeratozlu deri hastalıklarının tedavisi için diol ve alfa-hidroksi asitten oluşan bir karışımın kullanılması
ES2177625T3 (es) Citoquina cc-1 humana circulante.
FR2776188B1 (fr) Oleamide de glycylglycine en dermo-cosmetologie
ES2171743T3 (es) Derivados de amidinas e isotioureas como inhibidores de la enzima sintasa de oxido nitrico.
DE69625230D1 (de) Thrombininhibitoren
BG100248A (bg) Инхибитори на скваленсинтетаза
DK0793503T3 (da) Anvendelse af hepatocyt-vækstfaktor til inducering af profilerering og differentiering af hemotopoietiske celler
TR200001075T2 (tr) Tiamfenikol ve diklofenak içeren bileşimler.
ES2158441T3 (es) Arilheterociclos con actividad herbicida.
KR950701812A (ko) 렌티바이러스-유도된 질환의 치료에 유용한 생물학적으로 활성인 우레이도 유도체(Biologically active ureido dervatives useful in the treatment of lentivirus-induced sisease)
DK0483237T3 (da) Beskyttelse af cytolytisk aktivitet hos NK-celler i PBMC

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties