ATE216229T1 - Emulsion zur verabreichung eines sphingolipids und deren verwendung - Google Patents

Emulsion zur verabreichung eines sphingolipids und deren verwendung

Info

Publication number: ATE216229T1
Authority: AT; Austria
Prior art keywords: emulsion; sphingolipid; administration; cholesterol; cationic
Prior art date: 1994-12-07

Application number

AT95942970T

Other languages

English (en)

Inventor

Robert T Lyons

Original Assignee

Pharmacia & Upjohn Ab

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-07

Filing date

1995-12-01

Publication date

2002-05-15

1995-12-01 Application filed by Pharmacia & Upjohn Ab, Lilly Co Eli filed Critical Pharmacia & Upjohn Ab

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216229T1 publication Critical patent/ATE216229T1/de

Links

239000000839 emulsion Substances 0.000 title abstract 3
150000003408 sphingolipids Chemical class 0.000 title 1
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
230000002378 acidificating effect Effects 0.000 abstract 1
239000008346 aqueous phase Substances 0.000 abstract 1
-1 cationic sphingolipid Chemical class 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
230000000087 stabilizing effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT95942970T 1994-12-07 1995-12-01 Emulsion zur verabreichung eines sphingolipids und deren verwendung ATE216229T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/351,635 US5635536A (en)	1994-12-07	1994-12-07	Emulsion suitable for administering a sphingolipid
PCT/US1995/015687 WO1996017603A1 (en)	1994-12-07	1995-12-01	Emulsion suitable for administering a sphingolipid and use thereof

Publications (1)

Publication Number	Publication Date
ATE216229T1 true ATE216229T1 (de)	2002-05-15

Family

ID=23381694

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95942970T ATE216229T1 (de)	1994-12-07	1995-12-01	Emulsion zur verabreichung eines sphingolipids und deren verwendung

Country Status (10)

Country	Link
US (2)	US5635536A (de)
EP (1)	EP0799035B1 (de)
JP (1)	JPH10510267A (de)
AT (1)	ATE216229T1 (de)
AU (1)	AU4414096A (de)
DE (1)	DE69526450T2 (de)
DK (1)	DK0799035T3 (de)
ES (1)	ES2177676T3 (de)
PT (1)	PT799035E (de)
WO (1)	WO1996017603A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6720184B1 (en)	1991-08-05	2004-04-13	Emory University	Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination
AU692255B2 (en) *	1995-04-24	1998-06-04	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Self-emulsifiable formulation producing an oil-in-water emulsion
US6982142B2 (en)	1997-12-01	2006-01-03	John Wayne Cancer Institute	Methods for screening therapeutically effective agents
CA2320117A1 (en) *	1998-02-12	1999-08-19	Emory University	Sphingolipid derivatives and their methods of use
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
BR9911457A (pt)	1998-06-24	2001-12-11	Univ Emory	Uso de 3'-azida-2', 3'-dideoxiuridina em combinaçãocom drogas anti-hiv adicionais para a manufaturade um medicamento para o tratamento de hiv
EP1091745B1 (de)	1998-06-29	2008-10-01	Children's Hospital Of Los Angeles	Behandlung hyperproliferativer erkrankungen
US6368831B1 (en)	1998-06-29	2002-04-09	Childrens Hospital Los Angeles	Treatment of hyperproliferative disorders
JP4198318B2 (ja)	1998-08-19	2008-12-17	ヤーゴテックアクチェンゲゼルシャフト	プロポフォールの注射可能水性分散物
GB2359747B (en) *	2000-02-29	2002-04-24	Maelor Pharmaceuticals Ltd	Anaesthetic formulations
TWI230073B (en) *	2001-12-10	2005-04-01	Kao Corp	Ceramide emulsifier
WO2004075834A2 (en) *	2003-02-21	2004-09-10	Childrens Hospital Los Angeles Research Institute	Stabilized pharmaceutical compositions of safingol and methods of using the same
JP2006028109A (ja) *	2004-07-20	2006-02-02	Kao Corp	水中油型乳化組成物
US8557861B2 (en)	2004-09-28	2013-10-15	Mast Therapeutics, Inc.	Low oil emulsion compositions for delivering taxoids and other insoluble drugs
WO2011044207A2 (en) *	2009-10-06	2011-04-14	L'oreal S.A.	Compositions containing a high concentration of polar sphingolipid(s)
JP6960984B2 (ja) *	2019-12-26	2021-11-05	三菱電機株式会社	電子装置及びその絶縁部材

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1792410B2 (de) *	1967-09-01	1980-03-13	Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm	Arzneimittelzubereitung zur intravenösen Injektion
JPS6030652B2 (ja) *	1979-05-07	1985-07-17	株式会社ミドリ十字	静脈注射用脂肪乳剤
IT1171432B (it) *	1981-08-03	1987-06-10	Fidia Farmaceutici	Amidi organiche derivate da lipidi azotati utilizzabili come farmaci
US4937232A (en) *	1986-09-15	1990-06-26	Duke University	Inhibition of protein kinase C by long-chain bases
US4816450A (en) *	1986-09-15	1989-03-28	Duke University	Inhibition of protein kinase C by long-chain bases
US5364632A (en) *	1989-04-05	1994-11-15	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Medicinal emulsions
AU614465B2 (en) *	1989-04-05	1991-08-29	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Medicinal emulsions
FR2652002B1 (fr) *	1989-09-21	1991-11-29	Oreal	Nouveaux composes lipidiques derives des sphingosines, leur procede de preparation et leurs applications, notamment en cosmetique et en dermopharmacie.
US5198470A (en) *	1989-09-21	1993-03-30	L'oreal	Lipid compounds derived from sphingosines, process for preparing these and their applications, in particular in cosmetics and in the pharmacy of skin conditions
DE4015108A1 (de) *	1990-05-11	1991-11-14	Leopold Pharma Gmbh	Stabile emulsion zur applikation pharmakologisch aktiver wirkstoffe
US5149794A (en) *	1990-11-01	1992-09-22	State Of Oregon	Covalent lipid-drug conjugates for drug targeting
USH1168H (en) *	1991-08-21	1993-04-06	The United States Of America As Represented By The Secretary Of The Navy	Inhibitors of protein kinase C activity as protectors against septic shock and reducers of ARDS

1994
- 1994-12-07 US US08/351,635 patent/US5635536A/en not_active Expired - Fee Related
1995
- 1995-12-01 DK DK95942970T patent/DK0799035T3/da active
- 1995-12-01 AT AT95942970T patent/ATE216229T1/de not_active IP Right Cessation
- 1995-12-01 WO PCT/US1995/015687 patent/WO1996017603A1/en not_active Ceased
- 1995-12-01 DE DE69526450T patent/DE69526450T2/de not_active Expired - Fee Related
- 1995-12-01 JP JP8517678A patent/JPH10510267A/ja not_active Ceased
- 1995-12-01 PT PT95942970T patent/PT799035E/pt unknown
- 1995-12-01 EP EP95942970A patent/EP0799035B1/de not_active Expired - Lifetime
- 1995-12-01 AU AU44140/96A patent/AU4414096A/en not_active Abandoned
- 1995-12-01 ES ES95942970T patent/ES2177676T3/es not_active Expired - Lifetime
1996
- 1996-07-16 US US08/680,993 patent/US5677341A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0799035A1 (de)	1997-10-08
DK0799035T3 (da)	2002-07-22
ES2177676T3 (es)	2002-12-16
US5635536A (en)	1997-06-03
US5677341A (en)	1997-10-14
EP0799035A4 (de)	1999-06-09
DE69526450D1 (de)	2002-05-23
EP0799035B1 (de)	2002-04-17
DE69526450T2 (de)	2002-11-14
WO1996017603A1 (en)	1996-06-13
JPH10510267A (ja)	1998-10-06
AU4414096A (en)	1996-06-26
PT799035E (pt)	2002-09-30

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Legal Events

Date	Code	Title	Description
2002-11-15	UEP	Publication of translation of european patent specification
2007-09-15	REN	Ceased due to non-payment of the annual fee