ES2177676T3 - Emulsion adecuada para administrar un esfingolipido y uso de la misma. - Google Patents
Emulsion adecuada para administrar un esfingolipido y uso de la misma.Info
- Publication number
- ES2177676T3 ES2177676T3 ES95942970T ES95942970T ES2177676T3 ES 2177676 T3 ES2177676 T3 ES 2177676T3 ES 95942970 T ES95942970 T ES 95942970T ES 95942970 T ES95942970 T ES 95942970T ES 2177676 T3 ES2177676 T3 ES 2177676T3
- Authority
- ES
- Spain
- Prior art keywords
- sphingolipide
- administer
- emulsion
- adequate emulsion
- adequate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000839 emulsion Substances 0.000 title abstract 3
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- -1 cationic sphingolipid Chemical class 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE PRESENTA UNA EMULSION ACIDICA QUE CONTIENE UN LIPOIDE DISPERSADO EN UNA FASE ACUOSA, UN ESFINGOLIPIDO CATIONICO Y UNA CANTIDAD ESTABILIZANTE DE SURFACTANTE NO IONICO Y COLESTEROL, ASI COMO UN METODO PARA LA ADMINISTRACION DE LA EMULSION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/351,635 US5635536A (en) | 1994-12-07 | 1994-12-07 | Emulsion suitable for administering a sphingolipid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2177676T3 true ES2177676T3 (es) | 2002-12-16 |
Family
ID=23381694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95942970T Expired - Lifetime ES2177676T3 (es) | 1994-12-07 | 1995-12-01 | Emulsion adecuada para administrar un esfingolipido y uso de la misma. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5635536A (es) |
| EP (1) | EP0799035B1 (es) |
| JP (1) | JPH10510267A (es) |
| AT (1) | ATE216229T1 (es) |
| AU (1) | AU4414096A (es) |
| DE (1) | DE69526450T2 (es) |
| DK (1) | DK0799035T3 (es) |
| ES (1) | ES2177676T3 (es) |
| PT (1) | PT799035E (es) |
| WO (1) | WO1996017603A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6720184B1 (en) | 1991-08-05 | 2004-04-13 | Emory University | Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination |
| US5965160A (en) * | 1995-04-24 | 1999-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsifiable formulation producing an oil-in-water emulsion |
| US6982142B2 (en) | 1997-12-01 | 2006-01-03 | John Wayne Cancer Institute | Methods for screening therapeutically effective agents |
| DE69943314D1 (de) * | 1998-02-12 | 2011-05-12 | Kapil N Bhalla | Sphingolipid-derivate und verfahren zu deren verwendung |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| CA2335617C (en) * | 1998-06-24 | 2009-12-15 | Novirio Pharmaceuticals Limited | Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv |
| US6368831B1 (en) | 1998-06-29 | 2002-04-09 | Childrens Hospital Los Angeles | Treatment of hyperproliferative disorders |
| AU4724599A (en) | 1998-06-29 | 2000-01-17 | Children's Hospital Of Los Angeles | Treatment of hyperproliferative disorders |
| DE69912441T2 (de) | 1998-08-19 | 2004-08-19 | Skyepharma Canada Inc., Verdun | Injizierbare wässerige propofoldispersionen |
| GB2359747B (en) * | 2000-02-29 | 2002-04-24 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
| AU2002354131A1 (en) * | 2001-12-10 | 2003-06-23 | Kao Corporation | Ceramide emulsions |
| WO2004075834A2 (en) * | 2003-02-21 | 2004-09-10 | Childrens Hospital Los Angeles Research Institute | Stabilized pharmaceutical compositions of safingol and methods of using the same |
| JP2006028109A (ja) * | 2004-07-20 | 2006-02-02 | Kao Corp | 水中油型乳化組成物 |
| US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| WO2011044207A2 (en) * | 2009-10-06 | 2011-04-14 | L'oreal S.A. | Compositions containing a high concentration of polar sphingolipid(s) |
| JP6960984B2 (ja) * | 2019-12-26 | 2021-11-05 | 三菱電機株式会社 | 電子装置及びその絶縁部材 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1792410B2 (de) * | 1967-09-01 | 1980-03-13 | Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm | Arzneimittelzubereitung zur intravenösen Injektion |
| JPS6030652B2 (ja) * | 1979-05-07 | 1985-07-17 | 株式会社ミドリ十字 | 静脈注射用脂肪乳剤 |
| IT1171432B (it) * | 1981-08-03 | 1987-06-10 | Fidia Farmaceutici | Amidi organiche derivate da lipidi azotati utilizzabili come farmaci |
| US4816450A (en) * | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
| US4937232A (en) * | 1986-09-15 | 1990-06-26 | Duke University | Inhibition of protein kinase C by long-chain bases |
| US5364632A (en) * | 1989-04-05 | 1994-11-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
| AU614465B2 (en) * | 1989-04-05 | 1991-08-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
| US5198470A (en) * | 1989-09-21 | 1993-03-30 | L'oreal | Lipid compounds derived from sphingosines, process for preparing these and their applications, in particular in cosmetics and in the pharmacy of skin conditions |
| FR2652002B1 (fr) * | 1989-09-21 | 1991-11-29 | Oreal | Nouveaux composes lipidiques derives des sphingosines, leur procede de preparation et leurs applications, notamment en cosmetique et en dermopharmacie. |
| DE4015108A1 (de) * | 1990-05-11 | 1991-11-14 | Leopold Pharma Gmbh | Stabile emulsion zur applikation pharmakologisch aktiver wirkstoffe |
| US5149794A (en) * | 1990-11-01 | 1992-09-22 | State Of Oregon | Covalent lipid-drug conjugates for drug targeting |
| USH1168H (en) * | 1991-08-21 | 1993-04-06 | The United States Of America As Represented By The Secretary Of The Navy | Inhibitors of protein kinase C activity as protectors against septic shock and reducers of ARDS |
-
1994
- 1994-12-07 US US08/351,635 patent/US5635536A/en not_active Expired - Fee Related
-
1995
- 1995-12-01 PT PT95942970T patent/PT799035E/pt unknown
- 1995-12-01 AT AT95942970T patent/ATE216229T1/de not_active IP Right Cessation
- 1995-12-01 EP EP95942970A patent/EP0799035B1/en not_active Expired - Lifetime
- 1995-12-01 JP JP8517678A patent/JPH10510267A/ja not_active Ceased
- 1995-12-01 AU AU44140/96A patent/AU4414096A/en not_active Abandoned
- 1995-12-01 ES ES95942970T patent/ES2177676T3/es not_active Expired - Lifetime
- 1995-12-01 DK DK95942970T patent/DK0799035T3/da active
- 1995-12-01 DE DE69526450T patent/DE69526450T2/de not_active Expired - Fee Related
- 1995-12-01 WO PCT/US1995/015687 patent/WO1996017603A1/en not_active Ceased
-
1996
- 1996-07-16 US US08/680,993 patent/US5677341A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10510267A (ja) | 1998-10-06 |
| AU4414096A (en) | 1996-06-26 |
| WO1996017603A1 (en) | 1996-06-13 |
| DE69526450T2 (de) | 2002-11-14 |
| US5635536A (en) | 1997-06-03 |
| EP0799035A1 (en) | 1997-10-08 |
| EP0799035A4 (en) | 1999-06-09 |
| DE69526450D1 (de) | 2002-05-23 |
| ATE216229T1 (de) | 2002-05-15 |
| DK0799035T3 (da) | 2002-07-22 |
| EP0799035B1 (en) | 2002-04-17 |
| PT799035E (pt) | 2002-09-30 |
| US5677341A (en) | 1997-10-14 |
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