ATE217859T1 - Verfahren zur herstellung von optisch aktiven mevalonolactonen - Google Patents

Verfahren zur herstellung von optisch aktiven mevalonolactonen

Info

Publication number
ATE217859T1
ATE217859T1 AT95909953T AT95909953T ATE217859T1 AT E217859 T1 ATE217859 T1 AT E217859T1 AT 95909953 T AT95909953 T AT 95909953T AT 95909953 T AT95909953 T AT 95909953T AT E217859 T1 ATE217859 T1 AT E217859T1
Authority
AT
Austria
Prior art keywords
fluid
flow
circuit
inlet port
outlet port
Prior art date
Application number
AT95909953T
Other languages
German (de)
English (en)
Inventor
Hirokazu Ikeda
Tatsushi Murakami
Hiroo Matsumoto
Yoshio Ohara
Hiroyashu Kanda
Original Assignee
Daicel Chem
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chem, Nissan Chemical Ind Ltd filed Critical Daicel Chem
Application granted granted Critical
Publication of ATE217859T1 publication Critical patent/ATE217859T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3833—Chiral chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterised by the components to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT95909953T 1994-02-25 1995-02-22 Verfahren zur herstellung von optisch aktiven mevalonolactonen ATE217859T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2859494 1994-02-25
PCT/JP1995/000251 WO1995023125A1 (fr) 1994-02-25 1995-02-22 Procede de production de compose de mevalonolactone optiquement actif

Publications (1)

Publication Number Publication Date
ATE217859T1 true ATE217859T1 (de) 2002-06-15

Family

ID=12252925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909953T ATE217859T1 (de) 1994-02-25 1995-02-22 Verfahren zur herstellung von optisch aktiven mevalonolactonen

Country Status (11)

Country Link
US (1) US5939552A (fr)
EP (1) EP0747341B1 (fr)
JP (1) JP3776452B2 (fr)
KR (1) KR100355335B1 (fr)
CN (1) CN1136183C (fr)
AT (1) ATE217859T1 (fr)
AU (1) AU691582B2 (fr)
CA (1) CA2183071C (fr)
DE (1) DE69526784T2 (fr)
HU (1) HU214160B (fr)
WO (1) WO1995023125A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107492A (en) * 1998-05-08 2000-08-22 Ucb, S.A. Process for the preparation of levetiracetam
ATE302190T1 (de) 1998-07-23 2005-09-15 Nissan Chemical Ind Ltd Verfahren zur herstellung von chinolinderivaten und zwischenprodukten davon
KR100777553B1 (ko) * 2000-10-13 2007-11-16 다이셀 가가꾸 고교 가부시끼가이샤 광학활성인 (3ｒ, 5ｓ, 6ｅ)-7-[2-시클로프로필-4-(4-플루오로페닐)퀴놀린-3-일]-3,5-디히드록시-6-헵텐산 에틸의 제조방법
WO2002030853A1 (fr) * 2000-10-13 2002-04-18 Daicel Chemical Industries, Ltd. Matiere de remplissage pour separation d'isomeres optiques et procede permettant la separation d'isomeres optiques au moyen de cette matiere de remplissage
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
CN100349871C (zh) * 2002-09-20 2007-11-21 日产化学工业株式会社 制备3,5－二羟基－6－庚烯酸酯的方法
CN102285916B (zh) 2003-02-12 2015-02-25 日产化学工业株式会社 匹伐他汀钙的晶形
JP4294028B2 (ja) * 2003-04-24 2009-07-08 ダイセル化学工業株式会社 光学異性体用分離剤
KR20070066818A (ko) * 2003-04-24 2007-06-27 다이셀 가가꾸 고교 가부시끼가이샤 광학 이성체용 분리제
KR20050114282A (ko) * 2003-04-24 2005-12-05 다이셀 가가꾸 고교 가부시끼가이샤 광학 활성의 디히드록시헵텐산 에스테르의 분리 방법
CN100408562C (zh) * 2003-04-24 2008-08-06 大赛璐化学工业株式会社 (3r,5s,6e)-7-[2-环丙基-4-(4-氟苯基)喹啉-3-基]-3,5-二羟基-6-庚烯酸乙酯的制备方法
JP4340264B2 (ja) 2003-04-24 2009-10-07 ダイセル化学工業株式会社 光学異性体用分離剤
TWI343914B (en) * 2003-10-03 2011-06-21 Nissan Chemical Ind Ltd Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative
CA2574363A1 (fr) * 2004-07-23 2006-02-02 Pharmacia & Upjohn Company Llc Methode enantioselective pour la separation de derives d'acide 2-trifluoromethyl-2h-chromene-3-carboxylique
US7627159B2 (en) * 2004-10-28 2009-12-01 Siemens Medical Solutions Usa, Inc. 2D visualization for rib analysis
JP2006150214A (ja) 2004-11-29 2006-06-15 Daicel Chem Ind Ltd 光学異性体用分離剤及び光学異性体用分離カラム
US8053543B2 (en) * 2006-05-09 2011-11-08 National University Corporation Nagoya University Filler for optical isomer separation
JPWO2007148834A1 (ja) 2006-06-23 2009-11-19 ダイセル化学工業株式会社 光学異性体の分析方法又は分離方法
CN101259397B (zh) * 2007-12-21 2010-12-15 中国科学院山西煤炭化学研究所 一种模拟移动床反应器及其应用方法
US8017017B2 (en) 2008-08-26 2011-09-13 Daicel Chemical Industries, Ltd. Method for producing a target substance using a simulated moving bed chromatography separation system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041507A (ja) * 1983-08-12 1985-03-05 Mitsubishi Kasei Techno Engineers Kk クロマト分離装置の制御方法
JPS60226829A (ja) * 1984-03-29 1985-11-12 Daicel Chem Ind Ltd 多糖誘導体より成る分離剤
JPH0718849B2 (ja) * 1986-03-12 1995-03-06 ダイセル化学工業株式会社 分離剤の製造方法
JPH03100459A (ja) * 1989-09-14 1991-04-25 Sumitomo Heavy Ind Ltd 擬似移動床式クロマト分離法
JP2925753B2 (ja) * 1990-02-23 1999-07-28 ダイセル化学工業株式会社 光学異性体の分離方法
JPH0695090B2 (ja) * 1990-09-21 1994-11-24 川崎重工業株式会社 擬似移動床式液体クロマト分離装置
JP3181349B2 (ja) * 1991-03-04 2001-07-03 ダイセル化学工業株式会社 多糖誘導体及びその製造法、並びに分離剤
JP3528186B2 (ja) * 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
JP3010816B2 (ja) * 1991-08-22 2000-02-21 ダイセル化学工業株式会社 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法

Also Published As

Publication number Publication date
CA2183071A1 (fr) 1995-08-31
KR100355335B1 (ko) 2003-04-11
DE69526784D1 (de) 2002-06-27
DE69526784T2 (de) 2002-09-05
CN1136183C (zh) 2004-01-28
HU9602291D0 (en) 1996-10-28
AU1823195A (en) 1995-09-11
JP3776452B2 (ja) 2006-05-17
KR970701165A (ko) 1997-03-17
HUT74486A (en) 1997-01-28
CN1141028A (zh) 1997-01-22
US5939552A (en) 1999-08-17
HU214160B (hu) 1998-01-28
EP0747341B1 (fr) 2002-05-22
AU691582B2 (en) 1998-05-21
EP0747341A1 (fr) 1996-12-11
CA2183071C (fr) 2001-12-18
EP0747341A4 (fr) 1998-09-30
WO1995023125A1 (fr) 1995-08-31

Similar Documents

Publication Publication Date Title
ATE217859T1 (de) Verfahren zur herstellung von optisch aktiven mevalonolactonen
KR960010366B1 (ko) 크로마토 그래픽 분리 방법
TW351678B (en) Method for fractionating a solution to fractionate a solution
DE68923821D1 (de) Verfahren zur Gewinnung von Betain aus Melassen.
DK1106602T3 (da) Kromatografisk simulated moving bed-oprensning af aminosyrer
ATE503538T1 (de) Trennungsprozess durch simulierte fliessbettchromatographie
EP0719749A3 (fr) Procédé pour la séparation d'isomères optiques dans un lit mobile simulé
EP0134357A1 (fr) Procédé de séparation d'acides gras et un tamis moléculaire approprié
DK2186D0 (da) Fremgangsmaade og apparat til chromatografisk separation af biologiske makromolekyler
NZ509257A (en) Method for purifying haemoglobin by eluting the haemoglobin with tris(hydroxymethyl)aminomethane acetate buffer solution in an anion exchange chromatography column
ATE240141T1 (de) Methoden und apparat zum packen von chromatographiesäulen
ATE17890T1 (de) Fluessigkeits-chromatographensaeule, verfahren zu ihrer herstellung und ihre verwendung zur fraktionierung.
Deyl et al. Separation and partial characterization of Maillard reaction products by capillary zone electrophoresis
JP2740780B2 (ja) 擬似移動層装置
FI854096A0 (fi) Menetelmä adsorbentin höyrysteriloimiseksi ja steriloitu adsorptiokolonni
DE59910840D1 (de) Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen mit hohem Durchsatz
ATE52937T1 (de) Verfahren zur trennung von wasserstoffisotopen.
DE19629208A1 (de) Verwendung von modifizierten Membranen für "Simulated Moving Bed" Trennverfahren
KR950700377A (ko) 화학열 펌프용 흡착 블록 및 이의 제조방법(absorbent units for chemical heat pumps and process for their production)
ZA916803B (en) Process for determining the concentration of substances,apparatus for performing the process,use of the process for changing the concentration of a substance contained in a fluid,as well as a plant for this
RU2005104224A (ru) Способ разделения актинидов
DE50301526D1 (de) Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo(4.3.0)nonan unter Verwendung von Gegenstromchromatographie
KR960000276A (ko) 의사(擬似) 이동상 크로마토분리법
JPH10128005A (ja) 擬似移動床式分離装置の運転条件決定方法及び擬似移動床式分離装置
RU2000107344A (ru) Способ получения высокоочищенного монокомпонентного инсулина

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification