ATE218125T1 - Synthese von chiralen 3-hydroxy-2-pyrrolidinone derivativen - Google Patents
Synthese von chiralen 3-hydroxy-2-pyrrolidinone derivativenInfo
- Publication number
- ATE218125T1 ATE218125T1 AT96938364T AT96938364T ATE218125T1 AT E218125 T1 ATE218125 T1 AT E218125T1 AT 96938364 T AT96938364 T AT 96938364T AT 96938364 T AT96938364 T AT 96938364T AT E218125 T1 ATE218125 T1 AT E218125T1
- Authority
- AT
- Austria
- Prior art keywords
- iib
- iia
- image
- formulae
- iiib
- Prior art date
Links
- FRKGSNOMLIYPSH-UHFFFAOYSA-N 3-hydroxypyrrolidin-2-one Chemical class OC1CCNC1=O FRKGSNOMLIYPSH-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9524526.2A GB9524526D0 (en) | 1995-11-30 | 1995-11-30 | Chemical process |
| PCT/GB1996/002809 WO1997019920A1 (en) | 1995-11-30 | 1996-11-15 | Preparation of chiral 3-hydroxy-2-pyrrolidinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218125T1 true ATE218125T1 (de) | 2002-06-15 |
Family
ID=10784717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96938364T ATE218125T1 (de) | 1995-11-30 | 1996-11-15 | Synthese von chiralen 3-hydroxy-2-pyrrolidinone derivativen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5710283A (de) |
| EP (1) | EP0863872B1 (de) |
| JP (1) | JP2000501091A (de) |
| KR (1) | KR19990071765A (de) |
| CN (1) | CN1203586A (de) |
| AT (1) | ATE218125T1 (de) |
| AU (1) | AU7581696A (de) |
| DE (1) | DE69621450D1 (de) |
| GB (1) | GB9524526D0 (de) |
| TW (1) | TW457232B (de) |
| WO (1) | WO1997019920A1 (de) |
| ZA (1) | ZA969534B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105532688A (zh) * | 2016-01-14 | 2016-05-04 | 烟台顺隆化工科技有限公司 | 一种苹果园用除草剂 |
| CN110256479B (zh) * | 2019-04-25 | 2022-01-25 | 杭州师范大学 | 一种含硅酰基骨架的手性吡咯烷衍生物及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9225377D0 (en) * | 1992-12-04 | 1993-01-27 | Ici Plc | Herbicides |
| EP0763020A1 (de) * | 1994-06-02 | 1997-03-19 | Zeneca Limited | Substituierte pyrrolodone, thiazolidone oder oxazolidone als herbizide |
| AU712995B2 (en) * | 1995-05-10 | 1999-11-18 | G.D. Searle & Co. | Nitric oxide synthase inhibitors derived from cyclic amidines |
-
1995
- 1995-11-30 GB GBGB9524526.2A patent/GB9524526D0/en active Pending
-
1996
- 1996-11-13 ZA ZA969534A patent/ZA969534B/xx unknown
- 1996-11-15 AU AU75816/96A patent/AU7581696A/en not_active Abandoned
- 1996-11-15 AT AT96938364T patent/ATE218125T1/de not_active IP Right Cessation
- 1996-11-15 KR KR1019980704043A patent/KR19990071765A/ko not_active Ceased
- 1996-11-15 EP EP96938364A patent/EP0863872B1/de not_active Expired - Lifetime
- 1996-11-15 WO PCT/GB1996/002809 patent/WO1997019920A1/en not_active Ceased
- 1996-11-15 DE DE69621450T patent/DE69621450D1/de not_active Expired - Lifetime
- 1996-11-15 JP JP9520247A patent/JP2000501091A/ja active Pending
- 1996-11-15 CN CN96198672A patent/CN1203586A/zh active Pending
- 1996-11-21 US US08/749,350 patent/US5710283A/en not_active Expired - Fee Related
- 1996-12-19 TW TW085115690A patent/TW457232B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990071765A (ko) | 1999-09-27 |
| EP0863872A1 (de) | 1998-09-16 |
| DE69621450D1 (de) | 2002-07-04 |
| WO1997019920A1 (en) | 1997-06-05 |
| ZA969534B (en) | 1997-05-30 |
| TW457232B (en) | 2001-10-01 |
| AU7581696A (en) | 1997-06-19 |
| CN1203586A (zh) | 1998-12-30 |
| US5710283A (en) | 1998-01-20 |
| EP0863872B1 (de) | 2002-05-29 |
| JP2000501091A (ja) | 2000-02-02 |
| GB9524526D0 (en) | 1996-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |