ATE218139T1 - Xanthin-derivate - Google Patents

Xanthin-derivate

Info

Publication number
ATE218139T1
ATE218139T1 AT95909968T AT95909968T ATE218139T1 AT E218139 T1 ATE218139 T1 AT E218139T1 AT 95909968 T AT95909968 T AT 95909968T AT 95909968 T AT95909968 T AT 95909968T AT E218139 T1 ATE218139 T1 AT E218139T1
Authority
AT
Austria
Prior art keywords
lower alkyl
adenosine
different
same
represents hydrogen
Prior art date
Application number
AT95909968T
Other languages
German (de)
English (en)
Inventor
Fumio Suzuki
Nobuaki Koike
Junichi Shimada
Joji Nakamura
Shizuo Shiozaki
Shigeto Kitamura
Shunji Ichikawa
Hiroshi Kase
Hiromi Nonaka
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE218139T1 publication Critical patent/ATE218139T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95909968T 1994-02-23 1995-02-23 Xanthin-derivate ATE218139T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2573694 1994-02-23
PCT/JP1995/000267 WO1995023148A1 (en) 1994-02-23 1995-02-23 Xanthine derivative

Publications (1)

Publication Number Publication Date
ATE218139T1 true ATE218139T1 (de) 2002-06-15

Family

ID=12174110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909968T ATE218139T1 (de) 1994-02-23 1995-02-23 Xanthin-derivate

Country Status (7)

Country Link
US (1) US5703085A (2)
EP (1) EP0698607B1 (2)
AT (1) ATE218139T1 (2)
AU (1) AU1823895A (2)
CA (1) CA2161011A1 (2)
DE (1) DE69526822T2 (2)
WO (1) WO1995023148A1 (2)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066641A (en) * 1994-12-13 2000-05-23 Euro-Celtique S.A. Aryl thioxanthines
ATE325610T1 (de) * 1997-09-05 2006-06-15 Kyowa Hakko Kogyo Kk Xanthinderivative zur behandlung von hirnischämie
US6403567B1 (en) 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
USRE47351E1 (en) 1999-06-22 2019-04-16 Gilead Sciences, Inc. 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists
US6815446B1 (en) 1999-08-31 2004-11-09 Vanderbilt University Selective antagonists of A2B adenosine receptors
AU2001238665A1 (en) 2000-02-23 2001-09-03 Cv Therapeutics, Inc. Method of identifying partial agonists of the a2a receptor
FR2814077A1 (fr) * 2000-09-20 2002-03-22 Inst Nat Sante Rech Med Utilisation de modulateurs de recepteurs a l'adenosine pour reguler la fonction des netrines et/ou de leurs recepteurs
CN101543497A (zh) 2002-01-28 2009-09-30 协和发酵工业株式会社 治疗运动疾病患者的方法
US20050020915A1 (en) * 2002-07-29 2005-01-27 Cv Therapeutics, Inc. Myocardial perfusion imaging methods and compositions
JP2005538190A (ja) * 2002-07-29 2005-12-15 シーブイ・セラピューティクス・インコーポレイテッド 心筋潅流イメージング
US8470801B2 (en) 2002-07-29 2013-06-25 Gilead Sciences, Inc. Myocardial perfusion imaging methods and compositions
WO2005056016A1 (ja) * 2003-12-09 2005-06-23 Kyowa Hakko Kogyo Co., Ltd. 高次脳機能障害の予防および／または治療剤
CA2561383A1 (en) * 2004-03-30 2005-10-13 Kyowa Hakko Kogyo Co., Ltd. Prophylactic and/or therapeutic agents for chronic musculoskeletal pain
CN101076343A (zh) 2004-10-20 2007-11-21 Cv医药有限公司 A2a腺苷受体激动剂的应用
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
WO2007092372A1 (en) 2006-02-03 2007-08-16 Cv Therapeutics, Inc. Process for preparing an a2a-adenosine receptor agonist and its polymorphs
US20090081120A1 (en) * 2006-09-01 2009-03-26 Cv Therapeutics, Inc. Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods
WO2008028140A1 (en) * 2006-09-01 2008-03-06 Cv Therapeutics, Inc. Methods and compositions for increasing patient tolerability during myocardial imaging methods
US20080170990A1 (en) * 2006-09-29 2008-07-17 Cv Therapeutics, Inc. Methods for Myocardial Imaging in Patients Having a History of Pulmonary Disease
EP1939197A1 (en) * 2006-12-22 2008-07-02 Schwarz Pharma Ag 8-ethinylxanthine derivatives as selective A2A receptor antagonists
JP2010513353A (ja) * 2006-12-22 2010-04-30 シュバルツ ファルマ アクチェンゲゼルシャフト 選択的ａ２ａ受容体アンタゴニストとしての８−エチニルキサンチン誘導体
WO2008086096A2 (en) * 2007-01-03 2008-07-17 Cv Therapeutics, Inc. Myocardial perfusion imaging
GEP20125574B (en) * 2008-01-11 2012-07-10 Glenmark Pharmaceuticals Sa Fused pyrimidine derivatives as trpv3 modulators
US8119647B2 (en) 2008-04-23 2012-02-21 Glenmark Pharmaceuticals S.A. Fused pyrimidineone compounds as TRPV3 modulators
MX2011003168A (es) * 2008-09-29 2011-05-19 Gilead Sciences Inc Combinaciones de un agente de control de cantidad y un antagonista del receptor a-2-alfa para utilizarse en metodos de tomografia computarizada de detectores multiples.
US10184028B2 (en) 2016-01-11 2019-01-22 Industrial Technology Research Institute Method for preparing a polymer
US10287396B2 (en) 2016-01-11 2019-05-14 Industrial Technology Research Institute Polymer
US9994679B2 (en) * 2016-01-11 2018-06-12 Industrial Technology Research Institute Polymerization process of polyarylene sulfide
US10377705B2 (en) 2016-01-11 2019-08-13 Industrial Technology Research Institute Method for preparing polyarylene sulfide (PAS) monomer
US20220202822A1 (en) * 2019-04-24 2022-06-30 Sunshine Lake Pharma Co., Ltd. 8-substituted aryl vinyl xanthine derivatives and uses thereof
CN113248505B (zh) * 2021-06-09 2021-09-21 南京安杰新生物医药有限公司 伊曲茶碱去甲基杂质的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69130869T2 (de) * 1990-10-18 1999-06-10 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo Xanthinderivate
CA2093403C (en) * 1992-04-08 1999-08-10 Fumio Suzuki Therapeutic agent for parkinson's disease
PT628311E (pt) * 1992-07-08 2002-09-30 Kyowa Hakko Kogyo Kk Derivado de xantina com actividade antidepressiva
DE4325254A1 (de) * 1992-08-10 1994-02-17 Boehringer Ingelheim Kg Unsymmetrisch substituierte Xanthine
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
CA2112031A1 (en) * 1992-12-24 1994-06-25 Fumio Suzuki Xanthine derivatives
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists

Also Published As

Publication number Publication date
US5703085A (en) 1997-12-30
EP0698607A4 (2) 1996-03-27
WO1995023148A1 (en) 1995-08-31
AU1823895A (en) 1995-09-11
DE69526822D1 (en) 2002-07-04
EP0698607A1 (en) 1996-02-28
EP0698607B1 (en) 2002-05-29
CA2161011A1 (en) 1995-08-31
DE69526822T2 (de) 2003-01-23

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Legal Events

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