ATE218870T1 - Verbindungen von wirkstoffen, welche klopidogrel und antithrombotische mittel enthalten - Google Patents

Verbindungen von wirkstoffen, welche klopidogrel und antithrombotische mittel enthalten

Info

Publication number
ATE218870T1
ATE218870T1 AT97905218T AT97905218T ATE218870T1 AT E218870 T1 ATE218870 T1 AT E218870T1 AT 97905218 T AT97905218 T AT 97905218T AT 97905218 T AT97905218 T AT 97905218T AT E218870 T1 ATE218870 T1 AT E218870T1
Authority
AT
Austria
Prior art keywords
pct
klopidogrel
antithrbotic
agents
compounds
Prior art date
Application number
AT97905218T
Other languages
English (en)
Inventor
Andre Bernat
Jean-Marc Herbert
Pierre Savi
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9489354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE218870(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE218870T1 publication Critical patent/ATE218870T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Materials For Medical Uses (AREA)
AT97905218T 1996-02-19 1997-02-17 Verbindungen von wirkstoffen, welche klopidogrel und antithrombotische mittel enthalten ATE218870T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602027A FR2744918B1 (fr) 1996-02-19 1996-02-19 Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
PCT/FR1997/000296 WO1997029753A1 (fr) 1996-02-19 1997-02-17 Nouvelles associations de principes actifs contenant du clopidogrel et un antithrombotique

Publications (1)

Publication Number Publication Date
ATE218870T1 true ATE218870T1 (de) 2002-06-15

Family

ID=9489354

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97905218T ATE218870T1 (de) 1996-02-19 1997-02-17 Verbindungen von wirkstoffen, welche klopidogrel und antithrombotische mittel enthalten

Country Status (28)

Country Link
US (1) US5989578A (de)
EP (1) EP0881901B1 (de)
JP (1) JP3662028B2 (de)
KR (1) KR100295345B1 (de)
CN (1) CN1116042C (de)
AT (1) ATE218870T1 (de)
AU (1) AU715655B2 (de)
BR (1) BR9707556A (de)
CA (1) CA2246289C (de)
CZ (1) CZ292363B6 (de)
DE (2) DE69713287T2 (de)
DK (1) DK0881901T3 (de)
EE (1) EE03513B1 (de)
ES (1) ES2176684T3 (de)
FR (1) FR2744918B1 (de)
HU (1) HU225036B1 (de)
IL (1) IL125848A (de)
IS (1) IS1892B (de)
NO (2) NO317747B3 (de)
NZ (1) NZ331444A (de)
PL (1) PL187292B1 (de)
PT (1) PT881901E (de)
RU (1) RU2184547C2 (de)
SI (1) SI0881901T1 (de)
SK (1) SK284285B6 (de)
TR (1) TR199801608T2 (de)
UA (1) UA51695C2 (de)
WO (1) WO1997029753A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999045913A1 (en) * 1998-03-13 1999-09-16 Merck & Co., Inc. Combination therapy and composition for acute coronary ischemic syndrome and related conditions
DE69926750T2 (de) 1998-06-17 2006-06-29 Bristol-Myers Squibb Co. Vorbeugung des hirninfarkts durch kombinierte verabreichung von adp-rezeptor antiblutplättchen und antihypertensiven medikamenten
US6509348B1 (en) 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
FR2792836B3 (fr) 1999-04-30 2001-07-27 Sanofi Sa Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
FR2797400A1 (fr) * 1999-08-11 2001-02-16 Sanofi Synthelabo Associations a activite anti-thrombotique constituees de l'hydrogenosulfate de clopidogrel et d'un antagoniste des recepteurs gpiib/iiia et les compositions pharmaceutiques les contenant
EP1350511B1 (de) * 2000-12-25 2008-09-10 Daiichi Sankyo Company, Limited Aspirin enthaltende medizinische zusammensetzungen
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
FR2832929A1 (fr) * 2001-12-05 2003-06-06 Sanofi Synthelabo Compositions pharmaceutiques contenant un agent antithrombotique et un derive d'amines cycliques
AU2003270861A1 (en) * 2002-10-02 2004-04-23 Bristol-Myers Squibb Company Novel combination of a factor xa inhibitor and clopidogrel
ATE536889T1 (de) * 2003-07-08 2011-12-15 Accumetrics Inc Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
HUP0400982A2 (en) * 2004-05-17 2006-08-28 Chemor Kutato New veterinary product for honeybees
US20060222640A1 (en) * 2005-03-29 2006-10-05 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of thrombosis
RU2303980C2 (ru) * 2005-06-03 2007-08-10 ОАО "Щелковский витаминный завод" Лекарственная форма с антиагрегационным действием и способ ее изготовления
AU2006292946B2 (en) * 2005-09-21 2009-12-10 Chong Kun Dang Pharmaceutical Corp. Novel resinate complex of s-clopidogrel and production method thereof
WO2008048083A1 (es) * 2006-10-17 2008-04-24 Espinosa Abdala Leopoldo De Je Composiciones farmacéuticas para el tratamiento de enfermedades tromboembólicas
DE102006051625A1 (de) 2006-11-02 2008-05-08 Bayer Materialscience Ag Kombinationstherapie substituierter Oxazolidinone
MX2009011619A (es) 2007-04-27 2010-01-18 Cydex Pharmaceuticals Inc Formulaciones que contienen clopidogrel y eter sulfoalquilico-ciclodextrina y metodos de uso.
US20110038931A1 (en) * 2008-02-22 2011-02-17 Hanall Biopharma Co., Ltd. Composite preparation
DE102008032361A1 (de) 2008-07-10 2010-01-21 Csl Behring Gmbh Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie
KR101743591B1 (ko) 2009-05-13 2017-06-20 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
US8889902B2 (en) 2009-06-25 2014-11-18 Tetra, Sia Acetylsalicylic acid salts
US8563574B2 (en) 2009-12-07 2013-10-22 Academic Pharmaceuticals, Inc. Parenteral formulation of clopidogrel
CN102389436A (zh) * 2011-09-09 2012-03-28 北京阜康仁生物制药科技有限公司 一种抗血小板聚集的药物组合物
KR101675501B1 (ko) * 2011-11-02 2016-11-14 한국유나이티드제약 주식회사 클로피도그렐 및 아스피린의 복합제제
US8513278B2 (en) 2011-11-26 2013-08-20 Academic Pharmaceuticals, Inc. Parenteral dextrose formulation of clopidogrel
CN102406938A (zh) * 2011-11-29 2012-04-11 北京阜康仁生物制药科技有限公司 一种抗血栓的药物组合物
WO2013133620A1 (en) * 2012-03-09 2013-09-12 Yuhan Corporation Pharmaceutical composition comprising clopidogrel and aspirin and process for preparing the same
CN103720700A (zh) * 2012-10-10 2014-04-16 江苏威凯尔医药科技有限公司 含有阿斯匹林和维卡格雷的药用组合物
ES2657291T3 (es) 2013-04-22 2018-03-02 Csl Ltd. Un complejo covalente de factor de von Willebrand y factor VIII asociado por un puente disulfuro
KR101502588B1 (ko) 2013-05-01 2015-03-16 한국유나이티드제약 주식회사 클로피도그렐 및 아스피린의 복합제제
WO2015015062A1 (fr) * 2013-08-02 2015-02-05 Sanofi Comprime pharmaceutique comprenant de l'acide acetylsalicylique et du clopidogrel
HUP1400294A2 (hu) 2014-06-13 2015-12-28 Skillpharm Kft Clopidogrel új alkalmazása
CN107698620A (zh) 2015-06-23 2018-02-16 江苏天士力帝益药业有限公司 一种氘代噻吩并哌啶衍生物、制备方法及其应用
RU2745774C1 (ru) * 2020-08-14 2021-03-31 Алексей Викторович Марочков Способ лечения пациентов с новой коронавирусной инфекцией (covid-19)
US20230059869A1 (en) 2021-08-03 2023-02-23 Liqmeds Worldwide Limited Oral pharmaceutical solution of clopidogrel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2307538A1 (fr) * 1975-04-18 1976-11-12 Centre Etd Ind Pharma Nouveau medicament anti-agregant plaquettaire

Also Published As

Publication number Publication date
IL125848A (en) 2000-11-21
IS1892B (is) 2003-10-20
US5989578A (en) 1999-11-23
JP3662028B2 (ja) 2005-06-22
TR199801608T2 (xx) 1998-11-23
UA51695C2 (uk) 2002-12-16
WO1997029753A1 (fr) 1997-08-21
HUP9901144A2 (hu) 1999-09-28
BR9707556A (pt) 1999-07-27
DE69713287D1 (de) 2002-07-18
ES2176684T3 (es) 2002-12-01
AU1884497A (en) 1997-09-02
HU225036B1 (en) 2006-05-29
NO983812D0 (no) 1998-08-19
KR19990087163A (ko) 1999-12-15
FR2744918B1 (fr) 1998-05-07
RU2184547C2 (ru) 2002-07-10
EE03513B1 (et) 2001-10-15
KR100295345B1 (ko) 2001-08-07
CA2246289A1 (fr) 1997-08-21
NO317747B1 (no) 2004-12-13
EP0881901A1 (de) 1998-12-09
EP0881901B1 (de) 2002-06-12
SK110598A3 (en) 1999-01-11
SK284285B6 (sk) 2005-01-03
NO317747B3 (no) 2011-10-03
DE69713287T2 (de) 2002-12-19
DE122010000030I1 (de) 2010-10-21
AU715655B2 (en) 2000-02-10
CZ292363B6 (cs) 2003-09-17
HK1017850A1 (en) 1999-12-03
NO2010015I2 (no) 2012-11-12
HUP9901144A3 (en) 2001-04-28
CN1116042C (zh) 2003-07-30
NO2010015I1 (no) 2010-07-26
EE9800247A (et) 1999-02-15
DE122010000030I2 (de) 2012-06-21
PL327923A1 (en) 1999-01-04
SI0881901T1 (en) 2002-10-31
IL125848A0 (en) 1999-04-11
IS4827A (is) 1998-08-18
CZ249998A3 (cs) 1998-11-11
DK0881901T3 (da) 2002-10-07
CN1211922A (zh) 1999-03-24
PT881901E (pt) 2002-09-30
FR2744918A1 (fr) 1997-08-22
NZ331444A (en) 2001-04-27
NO983812L (no) 1998-10-09
CA2246289C (fr) 2003-12-16
PL187292B1 (pl) 2004-06-30
JPH11510818A (ja) 1999-09-21

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