PT101444A - Associacao sinergizante com efeito antagonista dos receptores nk1 e nk2, uso de produtos com actividade antagonista dos receptores nk1 e nk2 na sua preparacao e composicao farmaceutica contendo a referida associacao - Google Patents

Associacao sinergizante com efeito antagonista dos receptores nk1 e nk2, uso de produtos com actividade antagonista dos receptores nk1 e nk2 na sua preparacao e composicao farmaceutica contendo a referida associacao

Info

Publication number: PT101444A
Authority: PT; Portugal
Prior art keywords: receptors; association; antagonist; synergizing; preparation
Prior art date: 1993-01-19

Application number

PT101444A

Other languages

English (en)

Inventor

Claude Garret

Francois Montier

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-19

Filing date

1994-01-18

Publication date

1994-10-31

1994-01-18 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1994-10-31 Publication of PT101444A publication Critical patent/PT101444A/pt

Links

239000005557 antagonist Substances 0.000 title abstract 4
108010040718 Neurokinin-1 Receptors Proteins 0.000 title abstract 2
108010040722 Neurokinin-2 Receptors Proteins 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
108020003175 receptors Proteins 0.000 title 1
QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 abstract 1
102000002002 Neurokinin-1 Receptors Human genes 0.000 abstract 1
102100024304 Protachykinin-1 Human genes 0.000 abstract 1
101800003906 Substance P Proteins 0.000 abstract 1
102100037342 Substance-K receptor Human genes 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Plural Heterocyclic Compounds (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Soil Working Implements (AREA)
Electrotherapy Devices (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT101444A 1993-01-19 1994-01-18 Associacao sinergizante com efeito antagonista dos receptores nk1 e nk2, uso de produtos com actividade antagonista dos receptores nk1 e nk2 na sua preparacao e composicao farmaceutica contendo a referida associacao PT101444A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9300451A FR2700472B1 (fr)	1993-01-19	1993-01-19	Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.

Publications (1)

Publication Number	Publication Date
PT101444A true PT101444A (pt)	1994-10-31

Family

ID=9443143

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT101444A PT101444A (pt)	1993-01-19	1994-01-18	Associacao sinergizante com efeito antagonista dos receptores nk1 e nk2, uso de produtos com actividade antagonista dos receptores nk1 e nk2 na sua preparacao e composicao farmaceutica contendo a referida associacao

Country Status (25)

Country	Link
US (1)	US6177450B1 (pt)
EP (1)	EP0680323B1 (pt)
JP (1)	JP4341783B2 (pt)
KR (1)	KR100342152B1 (pt)
AT (1)	ATE150972T1 (pt)
AU (1)	AU682166B2 (pt)
BE (1)	BE1006705A3 (pt)
CA (1)	CA2152401C (pt)
CH (1)	CH687503A5 (pt)
DE (1)	DE69402411T2 (pt)
DK (1)	DK0680323T3 (pt)
ES (2)	ES2100689T3 (pt)
FR (1)	FR2700472B1 (pt)
GB (1)	GB2274777B (pt)
GR (1)	GR3023021T3 (pt)
IE (1)	IE940035A1 (pt)
IL (1)	IL108356A (pt)
IT (1)	IT1269185B (pt)
LU (1)	LU88442A1 (pt)
NO (1)	NO315077B1 (pt)
NZ (1)	NZ259728A (pt)
PT (1)	PT101444A (pt)
TW (1)	TW381021B (pt)
WO (1)	WO1994016697A1 (pt)
ZA (1)	ZA94333B (pt)

Families Citing this family (15)

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GB2287404A (en) *	1994-03-15	1995-09-20	Pfizer	Antiinflammatory and analgesic compositions
MX9703483A (es) *	1994-11-10	1997-08-30	Pfizer	Antagonistas del receptor de nk-1 para el tratamiento de trastornos oculares.
US5688960A (en) *	1995-05-02	1997-11-18	Schering Corporation	Substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US5696267A (en) *	1995-05-02	1997-12-09	Schering Corporation	Substituted oximes, hydrazones and olefins as neurokinin antagonists
FR2738245B1 (fr) *	1995-08-28	1997-11-21	Sanofi Sa	Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant
US5691362A (en) *	1996-06-05	1997-11-25	Schering-Plough Corporation	Substituted benzene-fused hetero- and carbocyclics as nuerokinin antagonists
US5789422A (en) *	1996-10-28	1998-08-04	Schering Corporation	Substituted arylalkylamines as neurokinin antagonists
EP0942732B1 (en) *	1996-12-02	2004-11-17	MERCK SHARP & DOHME LTD.	Use of nk-1 receptor antagonists for treating movement disorders
US6156749A (en) *	1997-12-01	2000-12-05	Merck Sharp & Dohme Limited	Use of NK-1 receptor antagonists for treating movement disorders
GB9816897D0 (en) *	1998-08-04	1998-09-30	Merck Sharp & Dohme	Therapeutic use
FR2792835B3 (fr) *	1999-04-27	2001-05-25	Sanofi Sa	Utilisation du saredutant pour la preparation de medicaments utiles dans le traitement ou la prevention de l'ensemble des troubles de l'humeur, des troubles de l'adaptation ou des troubles mixtes anxiete-depression
US20100189797A1 (en)	2002-06-10	2010-07-29	Julien Mendlewicz	Oral antidepressant formulation
EP2158910A1 (en) *	2003-10-27	2010-03-03	Novartis Ag	Use of neurokinin antagonists in the treatment of urinary incontinence
JP2008514612A (ja) *	2004-09-23	2008-05-08	ミシャロウ、アレクサンダー	対抗適応を誘発することにより神経伝達物質系を調節する方法
US20080045610A1 (en) *	2004-09-23	2008-02-21	Alexander Michalow	Methods for regulating neurotransmitter systems by inducing counteradaptations

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US5164372A (en)	1989-04-28	1992-11-17	Fujisawa Pharmaceutical Company, Ltd.	Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
FI97540C (fi)	1989-11-06	1997-01-10	Sanofi Sa	Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
GB8929070D0 (en)	1989-12-22	1990-02-28	Fujisawa Pharmaceutical Co	Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
US5232929A (en)	1990-11-28	1993-08-03	Pfizer Inc.	3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
IL99320A (en)	1990-09-05	1995-07-31	Sanofi Sa	Arylalkylamines, their preparation and pharmaceutical compositions containing them
FR2678267B1 (fr)	1991-06-25	1994-02-04	Elf Sanofi	Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.
GB9023116D0 (en)	1990-10-24	1990-12-05	Fujisawa Pharmaceutical Co	Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
EP0499313B1 (en)	1991-02-11	1997-06-11	MERCK SHARP & DOHME LTD.	Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
WO1992019254A1 (en)	1991-04-24	1992-11-12	Warner-Lambert Company	α-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY
FR2677361A1 (fr) *	1991-06-04	1992-12-11	Adir	Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2676053B1 (fr)	1991-05-03	1993-08-27	Sanofi Elf	Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr)	1991-05-03	1993-09-03	Sanofi Elf	Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676054B1 (fr)	1991-05-03	1993-09-03	Sanofi Elf	Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
BR9206161A (pt)	1991-06-20	1995-10-31	Pfizer	Derivados fluoroalcoxibenzilamino de heterociclos contendo nitrogénio
TW202432B (pt)	1991-06-21	1993-03-21	Pfizer
US5288730A (en)	1991-06-24	1994-02-22	Merck Sharp & Dohme Limited	Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
WO1993001169A2 (en)	1991-07-05	1993-01-21	Merck Sharp & Dohme Limited	Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
ATE133657T1 (de)	1991-07-05	1996-02-15	Merck Sharp & Dohme	Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung
EP0536817A1 (en)	1991-07-05	1993-04-14	MERCK SHARP & DOHME LTD.	Azabicyclic compounds as tachykinin antagonists
WO1993001159A1 (en)	1991-07-10	1993-01-21	Merck Sharp & Dohme Limited	Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
DE69208089T2 (de)	1991-07-10	1996-08-22	Merck Sharp & Dohme	Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung
MY110227A (en)	1991-08-12	1998-03-31	Ciba Geigy Ag	1-acylpiperindine compounds.
CA2112397A1 (en)	1991-08-20	1993-03-04	Raymond Baker	Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
ATE195867T1 (de)	1991-09-20	2000-09-15	Glaxo Group Ltd	Neue medizinische indikation für tachykinin- antagonisten
FI941212L (fi)	1991-09-26	1994-03-15	Pfizer	Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet
JP2553020B2 (ja)	1991-11-07	1996-11-13	吉富製薬株式会社	キヌクリジン化合物およびその医薬用途
FI942187L (fi)	1991-11-12	1994-05-11	Pfizer	Asyklisiä etyleenidiamiinijohdannaisia aine P-reseptoriantagonisteina
CA2083891A1 (en)	1991-12-03	1993-06-04	Angus Murray Macleod	Heterocyclic compounds, compositions containing them and their use in therapy
GB9201179D0 (en)	1992-01-21	1992-03-11	Glaxo Group Ltd	Chemical compounds
FR2688219B1 (fr)	1992-03-03	1994-07-08	Sanofi Elf	Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
US5328927A (en)	1992-03-03	1994-07-12	Merck Sharpe & Dohme, Ltd.	Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
JP2656702B2 (ja)	1992-03-23	1997-09-24	ファイザー製薬株式会社	ペプチド性キヌクリジン
FR2689888B1 (fr)	1992-04-10	1994-06-10	Rhone Poulenc Rorer Sa	Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
AU675786B2 (en)	1992-04-15	1997-02-20	Merck Sharp & Dohme Limited	Azacyclic compounds
CA2134964C (en)	1992-05-18	1997-12-30	Manoj C. Desai	Bridged aza-bicyclic derivatives as substance p antagonists

1993
- 1993-01-19 FR FR9300451A patent/FR2700472B1/fr not_active Expired - Fee Related
- 1993-12-22 LU LU88442A patent/LU88442A1/fr unknown
1994
- 1994-01-14 GB GB9400691A patent/GB2274777B/en not_active Revoked
- 1994-01-14 IT ITMI940039A patent/IT1269185B/it active IP Right Grant
- 1994-01-17 IL IL10835694A patent/IL108356A/en not_active IP Right Cessation
- 1994-01-18 ES ES94904685T patent/ES2100689T3/es not_active Expired - Lifetime
- 1994-01-18 WO PCT/FR1994/000055 patent/WO1994016697A1/fr not_active Ceased
- 1994-01-18 NZ NZ259728A patent/NZ259728A/en not_active IP Right Cessation
- 1994-01-18 EP EP94904685A patent/EP0680323B1/fr not_active Expired - Lifetime
- 1994-01-18 JP JP51672894A patent/JP4341783B2/ja not_active Expired - Fee Related
- 1994-01-18 AT AT94904685T patent/ATE150972T1/de active
- 1994-01-18 CA CA002152401A patent/CA2152401C/fr not_active Expired - Fee Related
- 1994-01-18 AU AU58627/94A patent/AU682166B2/en not_active Ceased
- 1994-01-18 CH CH00144/94A patent/CH687503A5/fr not_active IP Right Cessation
- 1994-01-18 DE DE69402411T patent/DE69402411T2/de not_active Expired - Lifetime
- 1994-01-18 TW TW083100392A patent/TW381021B/zh not_active IP Right Cessation
- 1994-01-18 PT PT101444A patent/PT101444A/pt not_active Application Discontinuation
- 1994-01-18 KR KR1019950702980A patent/KR100342152B1/ko not_active Expired - Fee Related
- 1994-01-18 IE IE003594A patent/IE940035A1/en not_active IP Right Cessation
- 1994-01-18 ZA ZA94333A patent/ZA94333B/xx unknown
- 1994-01-18 ES ES09400092A patent/ES2091712B1/es not_active Expired - Fee Related
- 1994-01-18 US US08/448,403 patent/US6177450B1/en not_active Expired - Fee Related
- 1994-01-18 DK DK94904685.8T patent/DK0680323T3/da active
- 1994-01-19 BE BE9400063A patent/BE1006705A3/fr not_active IP Right Cessation
1995
- 1995-07-17 NO NO19952828A patent/NO315077B1/no not_active IP Right Cessation
1997
- 1997-04-03 GR GR960403642T patent/GR3023021T3/el unknown

Also Published As

Publication number	Publication date
CA2152401A1 (fr)	1994-08-04
CH687503A5 (fr)	1996-12-31
ITMI940039A0 (it)	1994-01-14
EP0680323A1 (fr)	1995-11-08
GB2274777B (en)	1996-10-02
WO1994016697A1 (fr)	1994-08-04
NO952828D0 (no)	1995-07-17
IL108356A0 (en)	1994-04-12
NZ259728A (en)	1996-05-28
AU682166B2 (en)	1997-09-25
ATE150972T1 (de)	1997-04-15
ZA94333B (en)	1994-09-02
GR3023021T3 (en)	1997-07-30
CA2152401C (fr)	2008-08-26
NO952828L (no)	1995-07-17
ES2100689T3 (es)	1997-06-16
ITMI940039A1 (it)	1995-07-14
KR960700056A (ko)	1996-01-19
ES2091712B1 (es)	1997-08-01
AU5862794A (en)	1994-08-15
NO315077B1 (no)	2003-07-07
DE69402411T2 (de)	1997-10-30
ES2091712A1 (es)	1996-11-01
GB2274777A (en)	1994-08-10
KR100342152B1 (ko)	2003-02-26
BE1006705A3 (fr)	1994-11-22
FR2700472B1 (fr)	1995-02-17
GB9400691D0 (en)	1994-03-09
LU88442A1 (fr)	1994-10-03
IT1269185B (it)	1997-03-21
EP0680323B1 (fr)	1997-04-02
JP4341783B2 (ja)	2009-10-07
IE940035A1 (en)	1994-07-27
TW381021B (en)	2000-02-01
DE69402411D1 (de)	1997-05-07
US6177450B1 (en)	2001-01-23
FR2700472A1 (fr)	1994-07-22
JPH08505637A (ja)	1996-06-18
DK0680323T3 (da)	1997-10-20
IL108356A (en)	1998-09-24

Legal Events

Date	Code	Title	Description
1994-10-31	BB1A	Laying open of patent application	Effective date: 19940513
2000-10-31	FC3A	Refusal	Effective date: 20000727

Publication	Publication Date	Title
PT101444A (pt)	1994-10-31	Associacao sinergizante com efeito antagonista dos receptores nk1 e nk2, uso de produtos com actividade antagonista dos receptores nk1 e nk2 na sua preparacao e composicao farmaceutica contendo a referida associacao
IT1231434B (it)	1991-12-04	Composizione farmaceutica endovenosa e procedimento per la sua preparazione.
FI973828A0 (fi)	1997-09-29	Yhdisteitä ja koostumuksia aktiivisten aineiden annostelemiseksi
FI19991869L (fi)	1999-09-02	N-(aryylioksialkyyli)heteroaryylipiperidiinejä ja -heteroaryylipiperatsiineja ja niiden käyttö lääkkeinä
IT8621358A0 (it)	1986-08-01	Composizione farmaceutica adattivita' analgesica.
DE69713287D1 (de)	2002-07-18	Verbindungen von wirkstoffen, welche klopidogrel und antithrombotische mittel enthalten
FR2636532B1 (fr)	1993-11-19	Compositions pharmaceutiques
IT8323205A0 (it)	1983-10-07	Composizioni farmaceutiche adattivita' antiinfiammatoria e/o analgesica, non ulcerogene.
DE69014351D1 (de)	1995-01-12	Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
ES2062137T3 (es)	1994-12-16	Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea.
ITMI911147A0 (it)	1991-04-24	Composto ad attivita' terapeutica,sua preparazione e composizioni farmaceutiche che lo contengono
FR2703995B1 (fr)	1995-07-21	5-acylamino 1,2,4-thiadiazoles, leur preparation et compositions pharmaceutiques en contenant.
YU39396A (sh)	1999-09-27	Upotreba izolovanog prirodnog proteina gojaznosti za pripremu leka i njegova farmaceutska formulacija
IT1231342B (it)	1991-11-28	Derivati peptidici farmacologicamente attivi e preparazioni farmaceutiche che li contengono
FI956353L (fi)	1995-12-29	Farmaseuttiset valmisteet ja niiden käyttö etenkin neurodegeneratiivisten sairauksien hoidossa
RU95109891A (ru)	1997-02-10	19,11-перекрытые мостиками 4-эстрены, способ их получения, содержащая их фармацевтическая композиция и промежуточные соединения для их получения
DE59205998D1 (de)	1996-05-23	Arzneimittel mit antineoplastischer Wirkung enthaltend als Wirkstoff Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphat und Verfahren zu dessen Herstellung
FI961494L (fi)	1996-04-03	Farmaseuttisia koostumuksia ja niiden käyttö, etenkin hermoston rappeutumissairauksien hoitamiseksi
BR9106372A (pt)	1993-04-27	Derivados 1,5-benzotiazepinona,suas preparacoes e uso farmaceutico
FR2751967B1 (fr)	1998-10-09	Agents antipaludeens et antibabesioses et compositions pharmaceutiques les contenant
ITMI922216A1 (it)	1994-03-25	Nitrobenzoilalanine, procedimento per la loro preparazione, loro uso come agenti terapeutici e composizioni farmaceutiche che le contengono
IT8622051A0 (it)	1986-10-17	Composizioni farmaceutiche adattivita' cicatrizzante.
FI903653A7 (fi)	1991-01-22	Paikallisesti annettava farmaseuttinen koostumus
MX9203485A (es)	1992-07-01	Derivados de tieno sulfonamida, composiciones farmaceuticas y uso.
ITMI922832A1 (it)	1994-06-11	DERIVATI DELL'ESEROLINA AD ATTIVITAy ANTICOLINESTERASICA, PROCEDIMENTO PER LA LORO PREPARAZIONE E COMPOSIZIONI FARMACEUTICHE CHE LI CONTENGONO.