ATE219082T1 - Verfahren zur herstellung von radioaktiv markierten benzodiazepinrezeptor-mitteln und diese enthaltende zubereitung - Google Patents

Verfahren zur herstellung von radioaktiv markierten benzodiazepinrezeptor-mitteln und diese enthaltende zubereitung

Info

Publication number
ATE219082T1
ATE219082T1 AT97914331T AT97914331T ATE219082T1 AT E219082 T1 ATE219082 T1 AT E219082T1 AT 97914331 T AT97914331 T AT 97914331T AT 97914331 T AT97914331 T AT 97914331T AT E219082 T1 ATE219082 T1 AT E219082T1
Authority
AT
Austria
Prior art keywords
pct
same
preparation containing
benzodiazepine receptor
radioactive labeled
Prior art date
Application number
AT97914331T
Other languages
English (en)
Inventor
Christian Foged
Christer Halldin
Jukka Hiltunen
Lars Farde
Original Assignee
Map Medical Technologies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Map Medical Technologies Oy filed Critical Map Medical Technologies Oy
Application granted granted Critical
Publication of ATE219082T1 publication Critical patent/ATE219082T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K51/047—Benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97914331T 1996-03-18 1997-03-18 Verfahren zur herstellung von radioaktiv markierten benzodiazepinrezeptor-mitteln und diese enthaltende zubereitung ATE219082T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI961246A FI101305B (fi) 1996-03-18 1996-03-18 Radiofarmaseuttisena aineena käyttökelpoiset radiojodatut bentsodiatse piini-johdannaiset ja niiden käyttö diagnostiikassa
PCT/FI1997/000177 WO1997034898A1 (en) 1996-03-18 1997-03-18 Process for producing radiolabelled benzodiazepine receptor agents and composition containing the same

Publications (1)

Publication Number Publication Date
ATE219082T1 true ATE219082T1 (de) 2002-06-15

Family

ID=8545678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97914331T ATE219082T1 (de) 1996-03-18 1997-03-18 Verfahren zur herstellung von radioaktiv markierten benzodiazepinrezeptor-mitteln und diese enthaltende zubereitung

Country Status (7)

Country Link
US (1) US6015544A (de)
EP (1) EP0888354B1 (de)
AT (1) ATE219082T1 (de)
AU (1) AU2161397A (de)
DE (1) DE69713302T2 (de)
FI (1) FI101305B (de)
WO (1) WO1997034898A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070020A2 (en) 2001-03-02 2002-09-12 University Of Western Ontario Polymer precursors of radiolabeled compounds, and methods of making and using the same
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
MXPA06012758A (es) * 2004-05-04 2007-01-16 Hormos Medical Ltd Novedosas formulaciones orales de ospemifeno.
US20070224058A1 (en) * 2006-03-24 2007-09-27 Ingersoll-Rand Company Linear compressor assembly
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
KR101589314B1 (ko) 2007-08-20 2016-01-28 에보텍 인터내셔널 게엠베하 수면 장애의 치료
GB0917611D0 (en) * 2009-10-08 2009-11-25 Ge Healthcare Ltd Automated radiosynthesis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
US4745112A (en) * 1985-05-17 1988-05-17 A/S Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method III
DE202441T1 (de) * 1985-05-17 1987-03-19 Aktieselskabet Ferrosan, Soeborg Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.
ATE44381T1 (de) * 1985-10-17 1989-07-15 Ferrosan As Heterocyclische verbindungen und ihre herstellung und verwendung.
US5096695A (en) * 1988-08-05 1992-03-17 Hoffmann-Laroche Inc. Radioiodine benzodiazepines as brain imaging agents
CA1318668C (en) * 1988-08-05 1993-06-01 Heinz Carmann Radioiodine benzodiazepine derivatives

Also Published As

Publication number Publication date
FI961246A0 (fi) 1996-03-18
DE69713302T2 (de) 2003-01-30
US6015544A (en) 2000-01-18
DE69713302D1 (de) 2002-07-18
WO1997034898A1 (en) 1997-09-25
FI961246A7 (fi) 1997-09-19
FI101305B1 (fi) 1998-05-29
EP0888354A1 (de) 1999-01-07
AU2161397A (en) 1997-10-10
EP0888354B1 (de) 2002-06-12
FI101305B (fi) 1998-05-29

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee