ATE73803T1 - Imidazo(1,2-b>pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents

Imidazo(1,2-b>pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Info

Publication number
ATE73803T1
ATE73803T1 AT88402199T AT88402199T ATE73803T1 AT E73803 T1 ATE73803 T1 AT E73803T1 AT 88402199 T AT88402199 T AT 88402199T AT 88402199 T AT88402199 T AT 88402199T AT E73803 T1 ATE73803 T1 AT E73803T1
Authority
AT
Austria
Prior art keywords
alkyl group
imidazo
pyridazine
denotes hydrogen
manufacture
Prior art date
Application number
AT88402199T
Other languages
English (en)
Inventor
Jean Jacques Bourguignon
Camille George Wermuth
Paul Worms
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE73803T1 publication Critical patent/ATE73803T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT88402199T 1987-09-01 1988-09-01 Imidazo(1,2-b>pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. ATE73803T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8712167A FR2619818B1 (fr) 1987-09-01 1987-09-01 Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant
EP88402199A EP0306408B1 (de) 1987-09-01 1988-09-01 Imidazo[1,2-b]pyridazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
ATE73803T1 true ATE73803T1 (de) 1992-04-15

Family

ID=9354553

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402199T ATE73803T1 (de) 1987-09-01 1988-09-01 Imidazo(1,2-b>pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Country Status (8)

Country Link
US (1) US4910199A (de)
EP (1) EP0306408B1 (de)
JP (1) JPS6471877A (de)
AT (1) ATE73803T1 (de)
CA (1) CA1310318C (de)
DE (1) DE3869286D1 (de)
FR (1) FR2619818B1 (de)
PT (1) PT88373B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601011B1 (fr) * 1986-07-03 1988-10-28 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
FR2625201B1 (fr) * 1987-12-24 1990-06-15 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
US5912246A (en) * 1995-02-15 1999-06-15 Pharmacia & Upjohn Company Imidazo 1,2-a!pyridines for the treatment of CNS and cardiac diseases
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
TWI312347B (en) * 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
US7723336B2 (en) 2005-09-22 2010-05-25 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
US20070078136A1 (en) * 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
WO2009100375A1 (en) 2008-02-06 2009-08-13 Bristol-Myers Squibb Company Substituted imidazopyridazines useful as kinase inhibitors
UY31676A1 (es) * 2008-02-28 2009-09-30 "derivados de 3-metil-imidiazo-[1,2-b]-piridazina"
BRPI0911659B8 (pt) * 2008-04-15 2021-05-25 Eisai R&D Man Co Ltd composto 3-fenilpirazolo[5,1-b]tiazol e composição farmacêutica compreendendo o mesmo
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
JPWO2011043387A1 (ja) * 2009-10-08 2013-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
US9783543B2 (en) 2012-11-19 2017-10-10 Bayer Pharma Aktiengesellschaft Aminoimidazopyridazines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) * 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
US3828041A (en) * 1971-02-24 1974-08-06 American Cyanamid Co 6-substituted 3-nitroimidazo(1,2-b)pyridazines and method of preparing same
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines

Also Published As

Publication number Publication date
FR2619818B1 (fr) 1990-01-12
PT88373A (pt) 1989-07-31
CA1310318C (en) 1992-11-17
EP0306408B1 (de) 1992-03-18
FR2619818A1 (fr) 1989-03-03
JPS6471877A (en) 1989-03-16
EP0306408A1 (de) 1989-03-08
DE3869286D1 (de) 1992-04-23
US4910199A (en) 1990-03-20
PT88373B (pt) 1992-10-30

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties