DK231686A - Oxadiazolylimidazobenzodiazepinforbindelse, farmaceutisk praeparat indeholdende samme, fremgangsmaade til fremstilling af forbindelsen og fremgangsmaade til behandling af en centralnervesystemsygdom - Google Patents

Oxadiazolylimidazobenzodiazepinforbindelse, farmaceutisk praeparat indeholdende samme, fremgangsmaade til fremstilling af forbindelsen og fremgangsmaade til behandling af en centralnervesystemsygdom Download PDF

Info

Publication number: DK231686A
Authority: DK; Denmark
Prior art keywords: compound; procedure; oxadiazolylimidazobenzodiazepine; treating; preparing
Prior art date: 1985-05-17

Application number

DK231686A

Other languages

English (en)

Other versions

DK157194B (da

DK231686D0 (da

DK157194C (da

Inventor

Frank Waetjen

Mogens Engelstoft

John Bondo Hansen

Leif Helth Jensen

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-17

Filing date

1986-05-16

Publication date

1986-11-18

1985-05-17 Priority claimed from DK220485A external-priority patent/DK220485D0/da

1985-08-12 Priority claimed from DK365985A external-priority patent/DK365985D0/da

1985-10-17 Priority claimed from DK476985A external-priority patent/DK476985D0/da

1986-05-16 Application filed by Ferrosan As filed Critical Ferrosan As

1986-05-16 Priority to DK231686A priority Critical patent/DK157194C/da

1986-05-16 Publication of DK231686D0 publication Critical patent/DK231686D0/da

1986-11-18 Publication of DK231686A publication Critical patent/DK231686A/da

1989-11-20 Publication of DK157194B publication Critical patent/DK157194B/da

1990-04-23 Application granted granted Critical

1990-04-23 Publication of DK157194C publication Critical patent/DK157194C/da

Links

150000001875 compounds Chemical class 0.000 title abstract 2
-1 OXADIAZOLYLIMIDAZOBENZODIAZEPINE COMPOUND Chemical class 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
YZIWCURGXWGKPE-UHFFFAOYSA-N 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-4h-imidazo[1,5-a][1,4]benzodiazepin-6-one Chemical compound N1=CN2C3=CC=CC=C3C(=O)N(C)CC2=C1C(N=1)=NOC=1C1CC1 YZIWCURGXWGKPE-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Polyethers (AREA)
Phenolic Resins Or Amino Resins (AREA)
Polyesters Or Polycarbonates (AREA)
Plural Heterocyclic Compounds (AREA)

DK231686A 1985-05-17 1986-05-16 Oxadiazolylimidazobenzodiazepinforbindelse og farmaceutisk praeparat indeholdende samme DK157194C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK231686A DK157194C (da)	1985-05-17	1986-05-16	Oxadiazolylimidazobenzodiazepinforbindelse og farmaceutisk praeparat indeholdende samme

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
DK220485		1985-05-17
DK220485A DK220485D0 (da)	1985-05-17	1985-05-17	Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK365985		1985-08-12
DK365985A DK365985D0 (da)	1985-08-12	1985-08-12	Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK476985		1985-10-17
DK476985A DK476985D0 (da)	1985-10-17	1985-10-17	Fremgangsmaade til fremstilling af oxadiazolylderivater af imidazobenzodiazepiner og mellemprodukt til brug ved fremgangsmaaden
DK231686		1986-05-16
DK231686A DK157194C (da)	1985-05-17	1986-05-16	Oxadiazolylimidazobenzodiazepinforbindelse og farmaceutisk praeparat indeholdende samme

Publications (4)

Publication Number	Publication Date
DK231686D0 DK231686D0 (da)	1986-05-16
DK231686A true DK231686A (da)	1986-11-18
DK157194B DK157194B (da)	1989-11-20
DK157194C DK157194C (da)	1990-04-23

Family

ID=27221528

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK231686A DK157194C (da)	1985-05-17	1986-05-16	Oxadiazolylimidazobenzodiazepinforbindelse og farmaceutisk praeparat indeholdende samme
DK063288A DK160097C (da)	1985-05-17	1988-02-08	Fremgangsmaade til fremstilling af 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4h-imidazo(1,5-a)(1,4)benzodiazepin samt 3-cyclopropyl-3-isocyanomethyl-1,2,4-oxadiazol til anvendelse som udgangsmateriale ved fremgangsmaaden

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK063288A DK160097C (da)	1985-05-17	1988-02-08	Fremgangsmaade til fremstilling af 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4h-imidazo(1,5-a)(1,4)benzodiazepin samt 3-cyclopropyl-3-isocyanomethyl-1,2,4-oxadiazol til anvendelse som udgangsmateriale ved fremgangsmaaden

Country Status (16)

Country	Link
US (2)	US4622321A (da)
EP (1)	EP0201678B1 (da)
JP (1)	JPH01279877A (da)
AT (1)	ATE35266T1 (da)
AU (2)	AU590273B2 (da)
CA (2)	CA1256863A (da)
DE (2)	DE3660331D1 (da)
DK (2)	DK157194C (da)
ES (1)	ES8707205A1 (da)
FI (1)	FI82049C (da)
GR (1)	GR861260B (da)
IE (1)	IE59494B1 (da)
IL (1)	IL78790A (da)
NO (1)	NO163228C (da)
NZ (1)	NZ216202A (da)
PT (1)	PT82594B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0150040B1 (de) *	1984-01-19	1994-08-31	F. Hoffmann-La Roche Ag	Imidazodiazepin-Derivate
US4622321A (en) *	1985-05-17	1986-11-11	As Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method
US4771051A (en) *	1985-05-17	1988-09-13	A/S Ferrosan	3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
US4745112A (en) *	1985-05-17	1988-05-17	A/S Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method III
ATE80392T1 (de)	1985-10-17	1992-09-15	Novo Nordisk As	Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DK522187D0 (da) *	1987-10-06	1987-10-06	Ferrosan As	Imidozothienopyrimidiner, deres fremstilling og anvendelse
GB8823475D0 (en) *	1988-10-06	1988-11-16	Merck Sharp & Dohme	Chemical compounds
CA2143246C (en) *	1994-03-16	2000-08-22	Thierry Godel	Imidazodiazepines
FI101305B (fi) *	1996-03-18	1998-05-29	Map Medical Technologies Oy	Radiofarmaseuttisena aineena käyttökelpoiset radiojodatut bentsodiatse piini-johdannaiset ja niiden käyttö diagnostiikassa
US20100234359A1 (en) *	2007-08-20	2010-09-16	Evotec Neurosciences Gmbh	Treatment of sleep disorders
US20090054412A1 (en) *	2007-08-20	2009-02-26	John Alan Kemp	Treatment of Sleep Disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4031029A (en) *	1975-07-02	1977-06-21	General Electric Company	Process for producing uranium oxide rich compositions from uranium hexafluoride using fluid injection into the reaction zone
CA1143728A (en) *	1979-10-04	1983-03-29	Max Gerecke	Imidazodiazepine derivatives
JPS57123180A (en) *	1980-12-17	1982-07-31	Schering Ag	3-substituted beta-carboline, manufacture and psychotropic drug containing same
DK151808C (da) *	1982-11-16	1988-06-20	Ferrosan As	Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
EP0150040B1 (de) *	1984-01-19	1994-08-31	F. Hoffmann-La Roche Ag	Imidazodiazepin-Derivate
AU587802B2 (en) *	1985-03-08	1989-08-31	Ferrosan A/S	Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622321A (en) *	1985-05-17	1986-11-11	As Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method
ATE80392T1 (de) *	1985-10-17	1992-09-15	Novo Nordisk As	Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme

1986
- 1986-01-06 US US06/816,731 patent/US4622321A/en not_active Expired - Fee Related
- 1986-01-06 US US06/816,732 patent/US4622320A/en not_active Expired - Fee Related
- 1986-03-06 DE DE8686102951T patent/DE3660331D1/de not_active Expired
- 1986-03-06 EP EP86102951A patent/EP0201678B1/en not_active Expired
- 1986-03-06 DE DE198686102951T patent/DE201678T1/de active Pending
- 1986-03-06 AT AT86102951T patent/ATE35266T1/de not_active IP Right Cessation
- 1986-04-30 CA CA000507955A patent/CA1256863A/en not_active Expired
- 1986-04-30 CA CA000507956A patent/CA1256864A/en not_active Expired
- 1986-05-14 GR GR861260A patent/GR861260B/el unknown
- 1986-05-14 AU AU57429/86A patent/AU590273B2/en not_active Ceased
- 1986-05-15 IL IL78790A patent/IL78790A/xx not_active IP Right Cessation
- 1986-05-16 PT PT82594A patent/PT82594B/pt not_active IP Right Cessation
- 1986-05-16 DK DK231686A patent/DK157194C/da not_active IP Right Cessation
- 1986-05-16 ES ES555035A patent/ES8707205A1/es not_active Expired
- 1986-05-16 IE IE130686A patent/IE59494B1/en not_active IP Right Cessation
- 1986-05-16 NO NO861954A patent/NO163228C/no unknown
- 1986-05-16 NZ NZ216202A patent/NZ216202A/xx unknown
- 1986-05-16 FI FI862061A patent/FI82049C/fi not_active IP Right Cessation
1988
- 1988-02-08 DK DK063288A patent/DK160097C/da not_active IP Right Cessation
1989
- 1989-03-17 JP JP1065783A patent/JPH01279877A/ja active Pending
- 1989-08-04 AU AU39333/89A patent/AU614407B2/en not_active Ceased

Also Published As

Publication number	Publication date
DK157194B (da)	1989-11-20
DK231686D0 (da)	1986-05-16
CA1256863A (en)	1989-07-04
FI82049B (fi)	1990-09-28
ATE35266T1 (de)	1988-07-15
DE201678T1 (de)	1987-02-26
FI862061L (fi)	1986-11-18
IE861306L (en)	1986-11-17
PT82594A (en)	1986-06-01
EP0201678B1 (en)	1988-06-22
JPH01279877A (ja)	1989-11-10
NO163228B (no)	1990-01-15
ES555035A0 (es)	1987-07-16
PT82594B (pt)	1988-03-03
DE3660331D1 (en)	1988-07-28
NZ216202A (en)	1989-08-29
DK160097C (da)	1991-06-24
FI82049C (fi)	1991-01-10
US4622321A (en)	1986-11-11
ES8707205A1 (es)	1987-07-16
IL78790A0 (en)	1986-08-31
DK157194C (da)	1990-04-23
NO163228C (no)	1990-04-25
AU3933389A (en)	1989-11-23
DK63288D0 (da)	1988-02-08
CA1256864A (en)	1989-07-04
AU614407B2 (en)	1991-08-29
IE59494B1 (en)	1994-02-23
EP0201678A1 (en)	1986-11-20
AU5742986A (en)	1986-11-20
FI862061A0 (fi)	1986-05-16
AU590273B2 (en)	1989-11-02
GR861260B (en)	1986-09-10
DK63288A (da)	1988-02-08
NO861954L (no)	1986-11-18
IL78790A (en)	1990-01-18
US4622320A (en)	1986-11-11
DK160097B (da)	1991-01-28

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Legal Events

Date	Code	Title	Description
1997-01-13	PBP	Patent lapsed