ATE219096T1 - Dihydroderivate der antibiotika vom typ ll-e33288 - Google Patents

Dihydroderivate der antibiotika vom typ ll-e33288

Info

Publication number
ATE219096T1
ATE219096T1 AT87119344T AT87119344T ATE219096T1 AT E219096 T1 ATE219096 T1 AT E219096T1 AT 87119344 T AT87119344 T AT 87119344T AT 87119344 T AT87119344 T AT 87119344T AT E219096 T1 ATE219096 T1 AT E219096T1
Authority
AT
Austria
Prior art keywords
dihydroderivatives
antibiotic type
antibiotic
calichensis
pseudoaglycone
Prior art date
Application number
AT87119344T
Other languages
English (en)
Inventor
May Dean-Ming Lee
Michael Greenstein
David Paul Labeda
Amedeo Alexander Fantini
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/004,153 external-priority patent/US4939244A/en
Priority claimed from US07/004,154 external-priority patent/US5037651A/en
Priority claimed from US07/009,321 external-priority patent/US4970198A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE219096T1 publication Critical patent/ATE219096T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87119344T 1987-01-30 1987-12-30 Dihydroderivate der antibiotika vom typ ll-e33288 ATE219096T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/004,153 US4939244A (en) 1987-01-30 1987-01-30 Pseudoaglycones of LL-E33288 antibiotics
US07/004,154 US5037651A (en) 1987-01-30 1987-01-30 Dihydro derivatives of LL-E33288 antibiotics
US07/009,321 US4970198A (en) 1985-10-17 1987-01-30 Antitumor antibiotics (LL-E33288 complex)

Publications (1)

Publication Number Publication Date
ATE219096T1 true ATE219096T1 (de) 2002-06-15

Family

ID=27357575

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87119344T ATE219096T1 (de) 1987-01-30 1987-12-30 Dihydroderivate der antibiotika vom typ ll-e33288

Country Status (6)

Country Link
EP (2) EP0276485B1 (de)
JP (2) JP2791028B2 (de)
AT (1) ATE219096T1 (de)
DE (1) DE3752355T2 (de)
ES (1) ES2177518T3 (de)
SG (1) SG52432A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079233A (en) * 1987-01-30 1992-01-07 American Cyanamid Company N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
US5606040A (en) * 1987-10-30 1997-02-25 American Cyanamid Company Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
EP0330874A3 (de) * 1988-02-29 1989-10-18 American Cyanamid Company Antibakterielle und Antitumor-Mittel LL-E33288 epsilon-I und LL-E33288-epsilon-Br, deren Herstellungen und Zwischenprodukte
IL93733A (en) * 1989-04-14 1996-01-19 American Cyanamid Co Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group and targeted forms thereof
JP2013530891A (ja) * 2010-06-04 2013-08-01 スレッドレス クロージャーズ リミテッド 容器用密閉器
JP6077975B2 (ja) * 2013-09-30 2017-02-08 ヤンマー株式会社 軸受構造および作業車両

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3588213T2 (de) * 1984-11-16 1999-09-30 American Cyanamid Co., Wayne Antitumorale Antibiotika (Komplex LL-E-33288)
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics

Also Published As

Publication number Publication date
JP2791028B2 (ja) 1998-08-27
EP1215212A2 (de) 2002-06-19
DE3752355D1 (de) 2002-07-18
EP0276485A3 (de) 1990-09-12
DE3752355T2 (de) 2002-12-05
EP0276485A2 (de) 1988-08-03
SG52432A1 (en) 1998-09-28
EP1215212A3 (de) 2003-05-21
JPH1057093A (ja) 1998-03-03
JP3130270B2 (ja) 2001-01-31
EP0276485B1 (de) 2002-06-12
JPS63216494A (ja) 1988-09-08
ES2177518T3 (es) 2002-12-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee