ATE219146T1 - Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten - Google Patents

Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten

Info

Publication number
ATE219146T1
ATE219146T1 AT96902922T AT96902922T ATE219146T1 AT E219146 T1 ATE219146 T1 AT E219146T1 AT 96902922 T AT96902922 T AT 96902922T AT 96902922 T AT96902922 T AT 96902922T AT E219146 T1 ATE219146 T1 AT E219146T1
Authority
AT
Austria
Prior art keywords
new
lta
streptococcus
grop
isolated
Prior art date
Application number
AT96902922T
Other languages
English (en)
Inventor
Peter Truog
Peter Roethlisberger
Original Assignee
Lunamed Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lunamed Ag filed Critical Lunamed Ag
Application granted granted Critical
Publication of ATE219146T1 publication Critical patent/ATE219146T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96902922T 1995-01-30 1996-01-24 Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten ATE219146T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95101208 1995-01-30
PCT/EP1996/000309 WO1996023896A1 (en) 1995-01-30 1996-01-24 Antitumor and anticholesterol preparations containing a lipoteichoic acid from steptococcus

Publications (1)

Publication Number Publication Date
ATE219146T1 true ATE219146T1 (de) 2002-06-15

Family

ID=8218940

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96902922T ATE219146T1 (de) 1995-01-30 1996-01-24 Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten

Country Status (11)

Country Link
US (2) US6114161A (de)
EP (1) EP0807185B9 (de)
JP (1) JP3638955B2 (de)
CN (1) CN1113102C (de)
AT (1) ATE219146T1 (de)
AU (1) AU4714196A (de)
CA (1) CA2208780C (de)
DE (1) DE69621776T2 (de)
DK (1) DK0807185T3 (de)
ES (1) ES2178699T3 (de)
WO (1) WO1996023896A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE219146T1 (de) * 1995-01-30 2002-06-15 Lunamed Ag Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten
US6610293B1 (en) * 1997-06-16 2003-08-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
DE19728900A1 (de) * 1997-07-07 1999-01-14 Henkel Kgaa Hydrophile Glykoside
DE69943276D1 (de) * 1998-04-02 2011-04-21 Univ Oklahoma State Chondroitin-Synthase kodierendes DNA der Pasteurella multocida und Verwendungsverfahren
HUP0500634A3 (en) 2001-08-13 2006-03-28 Univ Florida Materials and methods to promote repair of nerve tissue
AU2003220115A1 (en) * 2002-05-20 2003-12-12 Board Of Regents, The University Of Texas System Methods and compositions for delivering enzymes and nucleic acid molecules to brain, bone, and other tissues
KR100443080B1 (ko) * 2002-07-11 2004-08-04 일동제약주식회사 콜레스테롤 저하능을 갖는 스트렙토코커스 페시움 균주
CA2507711A1 (en) * 2002-12-02 2004-06-17 Biosynexus Incorporated Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
GB0717442D0 (en) * 2007-09-07 2007-10-17 Isis Innovation Compositions and uses thereof
BR112012000953A8 (pt) * 2009-07-15 2017-12-26 Aimm Therapeutics Bv anticorpos de ligação a bactérias gram-positivas, sequência de ácido nucleico,seus usos e seu método de produção, células isolada ou produtora de anticorpo isolado ou recombinante, composições, e método de isolamento de bactérias
JP2013502456A (ja) * 2009-08-26 2013-01-24 アールエヌエー アイエヌシー リポタイコ酸由来の糖脂質及びこれを含む組成物
EP2380565A1 (de) 2010-03-31 2011-10-26 Lunamed AG Zusammensetzungen zur Zahnbehandlung, die Lipoteichonsäuren oder Teile davon, wie Mono- oder Polyglycerolphosphate, umfassen
ES2544808T3 (es) * 2011-03-11 2015-09-04 Universitätsklinikum Freiburg Miméticos sintéticos de LTA y uso de los mismos como componente de vacuna para la terapia y/o profilaxis de infecciones gram-positivas
EP2545909A1 (de) 2011-07-12 2013-01-16 Lunamed AG Kombination aus D-Aminosäuren und Lipoteichonsäure
EP2545911A1 (de) 2011-07-12 2013-01-16 Lunamed AG Verwendung von Lipoteichonsäure bei der Behandlung von nicht verkapselten Krebszellen
EP2545910A1 (de) 2011-07-12 2013-01-16 Lunamed AG Verwendung von Lipoteichonsäure bei der Behandlung von Krebs im Entzündungsstadium
EP2574237A1 (de) 2011-09-30 2013-04-03 Lunamed AG Verwendung von Lipoteichonsäure, Mono- oder Polyglycerophosphat zur antibakteriellen Vorbehandlung und insbesondere in medizinischen Geräten
EP2589387A1 (de) 2011-11-04 2013-05-08 Lunamed AG Verwendung einer Teichonsäure zur Behandlung von malignem Liquor cerebrospinalis im Gehirn
EP2589388A1 (de) 2011-11-04 2013-05-08 Lunamed AG Verwendung einer Teichonsäure zur Behandlung von maligner Aszites
KR20190137397A (ko) * 2018-06-01 2019-12-11 경희대학교 산학협력단 리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물
KR102259799B1 (ko) * 2018-06-01 2021-06-02 경희대학교 산학협력단 리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물
EP4081225A1 (de) 2019-12-27 2022-11-02 Biopolis, S.L. Verwendungen von lipoteichoicsäure aus bifidobakterien

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729461A (en) * 1970-12-23 1973-04-24 Us Agriculture Synthesis of glycosyl glycerides
SU787414A1 (ru) * 1978-10-05 1980-12-15 Московский Ордена Трудового Красного Знамени Институт Тонкой Химической Технологии Им. М.В. Ломоносова Способ получени 1,2-ди-0-пальмитоил- 3-0-/6-0-(1,2-ди-0-пальмитоил- - глицеро-3-0-фосфорил)- - глюкопиранозил/- -глицерина
US4678773A (en) * 1983-08-26 1987-07-07 Chugai Seiyaku Kabushiki Kaisha Antitumor agent
JPS61275217A (ja) * 1985-05-29 1986-12-05 Yakult Honsha Co Ltd グラム陰性桿菌感染症防御剤
JPS6456692A (en) * 1987-08-27 1989-03-03 Nisshin Oil Mills Ltd Production of sugar glycerol
JPS6467237A (en) * 1987-09-09 1989-03-13 Nisshin Oil Mills Ltd Novel surface active composition and emulsified composition combined therewith
NL9100510A (nl) * 1991-03-21 1992-10-16 Centraal Diergeneeskundig Inst Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens.
AU6362594A (en) * 1993-03-10 1994-09-26 Miles Inc. Hyaluronic acid used as a cancer treatment
ATE219146T1 (de) * 1995-01-30 2002-06-15 Lunamed Ag Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten

Also Published As

Publication number Publication date
DE69621776D1 (de) 2002-07-18
EP0807185B9 (de) 2002-12-11
US6214978B1 (en) 2001-04-10
DE69621776T2 (de) 2003-01-30
JPH11500901A (ja) 1999-01-26
CA2208780A1 (en) 1996-08-08
DK0807185T3 (da) 2002-10-07
CN1113102C (zh) 2003-07-02
CN1173206A (zh) 1998-02-11
US6114161A (en) 2000-09-05
ES2178699T3 (es) 2003-01-01
AU4714196A (en) 1996-08-21
WO1996023896A1 (en) 1996-08-08
CA2208780C (en) 2010-03-30
EP0807185B1 (de) 2002-06-12
EP0807185A1 (de) 1997-11-19
JP3638955B2 (ja) 2005-04-13

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