DK0807185T3 - Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus - Google Patents

Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus

Info

Publication number: DK0807185T3
Authority: DK; Denmark
Prior art keywords: new; lta; streptococcus; lipoteichoic acid; grop
Prior art date: 1995-01-30

Application number

DK96902922T

Other languages

Danish (da)

English (en)

Inventor

Peter Truog

Peter Roethlisberger

Original Assignee

Lunamed Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-30

Filing date

1996-01-24

Publication date

2002-10-07

1996-01-24 Application filed by Lunamed Ag filed Critical Lunamed Ag

2002-10-07 Application granted granted Critical

2002-10-07 Publication of DK0807185T3 publication Critical patent/DK0807185T3/da

Links

241000194017 Streptococcus Species 0.000 title abstract 3
239000002253 acid Substances 0.000 title abstract 2
230000000259 anti-tumor effect Effects 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical compound C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 1
QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 1
108010003272 Hyaluronate lyase Proteins 0.000 abstract 1
102000001974 Hyaluronidases Human genes 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
239000007857 degradation product Substances 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
125000003128 glycerophosphate group Chemical group 0.000 abstract 1
229960002773 hyaluronidase Drugs 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/51—Lyases (4)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK96902922T 1995-01-30 1996-01-24 Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus DK0807185T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95101208		1995-01-30
PCT/EP1996/000309 WO1996023896A1 (en)	1995-01-30	1996-01-24	Antitumor and anticholesterol preparations containing a lipoteichoic acid from steptococcus

Publications (1)

Publication Number	Publication Date
DK0807185T3 true DK0807185T3 (da)	2002-10-07

Family

ID=8218940

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96902922T DK0807185T3 (da)	1995-01-30	1996-01-24	Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus

Country Status (11)

Country	Link
US (2)	US6114161A (de)
EP (1)	EP0807185B9 (de)
JP (1)	JP3638955B2 (de)
CN (1)	CN1113102C (de)
AT (1)	ATE219146T1 (de)
AU (1)	AU4714196A (de)
CA (1)	CA2208780C (de)
DE (1)	DE69621776T2 (de)
DK (1)	DK0807185T3 (de)
ES (1)	ES2178699T3 (de)
WO (1)	WO1996023896A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0807185B9 (de) *	1995-01-30	2002-12-11	Lunamed AG	Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten
US6610293B1 (en)	1997-06-16	2003-08-26	The Henry M. Jackson Foundation For The Advancement Of Military Medicine	Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
DE19728900A1 (de) *	1997-07-07	1999-01-14	Henkel Kgaa	Hydrophile Glykoside
CA2326821C (en) *	1998-04-02	2010-09-28	The Board Of Regents Of The University Of Oklahoma	Nucleic acid encoding hyaluronan synthase and methods of use
CA2455827C (en) *	2001-08-13	2015-06-09	University Of Florida Research Foundation, Inc.	Materials and methods for nerve grafting comprising degrading chondroitin sulfate proteoglycan
AU2003220115A1 (en) *	2002-05-20	2003-12-12	Board Of Regents, The University Of Texas System	Methods and compositions for delivering enzymes and nucleic acid molecules to brain, bone, and other tissues
KR100443080B1 (ko) *	2002-07-11	2004-08-04	일동제약주식회사	콜레스테롤 저하능을 갖는 스트렙토코커스 페시움 균주
EP1567868A4 (de) *	2002-12-02	2008-02-06	Biosynexus Inc	ZELLWAND-TEICHONSûURE ALS ZIEL F RANTI-STAPHYLOCOCCUS-THERAPIEN UND -IMPFSTOFFE
GB0717442D0 (en) *	2007-09-07	2007-10-17	Isis Innovation	Compositions and uses thereof
CN102666583B (zh)	2009-07-15	2015-11-25	Aimm医疗股份公司	革兰氏阳性细菌特异性结合化合物
JP2013502456A (ja) *	2009-08-26	2013-01-24	アールエヌエーアイエヌシー	リポタイコ酸由来の糖脂質及びこれを含む組成物
EP2380565A1 (de)	2010-03-31	2011-10-26	Lunamed AG	Zusammensetzungen zur Zahnbehandlung, die Lipoteichonsäuren oder Teile davon, wie Mono- oder Polyglycerolphosphate, umfassen
EP2500349B1 (de) *	2011-03-11	2015-05-06	Universitätsklinikum Freiburg	Synthetische LTA-Mimetika und deren Verwendung als Impfstoffbestandteil zur Therapie und/oder Prophylaxe gegen grampositive Infektionen
EP2545911A1 (de)	2011-07-12	2013-01-16	Lunamed AG	Verwendung von Lipoteichonsäure bei der Behandlung von nicht verkapselten Krebszellen
EP2545910A1 (de)	2011-07-12	2013-01-16	Lunamed AG	Verwendung von Lipoteichonsäure bei der Behandlung von Krebs im Entzündungsstadium
EP2545909A1 (de)	2011-07-12	2013-01-16	Lunamed AG	Kombination aus D-Aminosäuren und Lipoteichonsäure
EP2574237A1 (de)	2011-09-30	2013-04-03	Lunamed AG	Verwendung von Lipoteichonsäure, Mono- oder Polyglycerophosphat zur antibakteriellen Vorbehandlung und insbesondere in medizinischen Geräten
EP2589387A1 (de)	2011-11-04	2013-05-08	Lunamed AG	Verwendung einer Teichonsäure zur Behandlung von malignem Liquor cerebrospinalis im Gehirn
EP2589388A1 (de)	2011-11-04	2013-05-08	Lunamed AG	Verwendung einer Teichonsäure zur Behandlung von maligner Aszites
KR20190137397A (ko) *	2018-06-01	2019-12-11	경희대학교 산학협력단	리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물
KR102259799B1 (ko) *	2018-06-01	2021-06-02	경희대학교 산학협력단	리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물
CN115279380A (zh)	2019-12-27	2022-11-01	佰欧波利斯有限公司	来自双歧杆菌的脂磷壁酸的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3729461A (en) *	1970-12-23	1973-04-24	Us Agriculture	Synthesis of glycosyl glycerides
SU787414A1 (ru) *	1978-10-05	1980-12-15	Московский Ордена Трудового Красного Знамени Институт Тонкой Химической Технологии Им. М.В. Ломоносова	Способ получени 1,2-ди-0-пальмитоил- 3-0-/6-0-(1,2-ди-0-пальмитоил- - глицеро-3-0-фосфорил)- - глюкопиранозил/- -глицерина
US4678773A (en) *	1983-08-26	1987-07-07	Chugai Seiyaku Kabushiki Kaisha	Antitumor agent
JPS61275217A (ja) *	1985-05-29	1986-12-05	Yakult Honsha Co Ltd	グラム陰性桿菌感染症防御剤
JPS6456692A (en) *	1987-08-27	1989-03-03	Nisshin Oil Mills Ltd	Production of sugar glycerol
JPS6467237A (en) *	1987-09-09	1989-03-13	Nisshin Oil Mills Ltd	Novel surface active composition and emulsified composition combined therewith
NL9100510A (nl) *	1991-03-21	1992-10-16	Centraal Diergeneeskundig Inst	Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens.
AU6362594A (en) *	1993-03-10	1994-09-26	Miles Inc.	Hyaluronic acid used as a cancer treatment
EP0807185B9 (de) *	1995-01-30	2002-12-11	Lunamed AG	Antitumorpräparate, die eine lipoteichonsäure aus streptococcus enthalten

1996
- 1996-01-24 EP EP96902922A patent/EP0807185B9/de not_active Expired - Lifetime
- 1996-01-24 AU AU47141/96A patent/AU4714196A/en not_active Abandoned
- 1996-01-24 CA CA2208780A patent/CA2208780C/en not_active Expired - Fee Related
- 1996-01-24 DE DE69621776T patent/DE69621776T2/de not_active Expired - Lifetime
- 1996-01-24 CN CN96191668A patent/CN1113102C/zh not_active Expired - Fee Related
- 1996-01-24 ES ES96902922T patent/ES2178699T3/es not_active Expired - Lifetime
- 1996-01-24 WO PCT/EP1996/000309 patent/WO1996023896A1/en not_active Ceased
- 1996-01-24 DK DK96902922T patent/DK0807185T3/da active
- 1996-01-24 AT AT96902922T patent/ATE219146T1/de active
- 1996-01-24 US US08/875,018 patent/US6114161A/en not_active Expired - Lifetime
- 1996-01-24 JP JP52322796A patent/JP3638955B2/ja not_active Expired - Fee Related
1999
- 1999-01-15 US US09/232,106 patent/US6214978B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69621776T2 (de)	2003-01-30
EP0807185A1 (de)	1997-11-19
US6214978B1 (en)	2001-04-10
JPH11500901A (ja)	1999-01-26
US6114161A (en)	2000-09-05
EP0807185B1 (de)	2002-06-12
ES2178699T3 (es)	2003-01-01
AU4714196A (en)	1996-08-21
WO1996023896A1 (en)	1996-08-08
DE69621776D1 (de)	2002-07-18
CA2208780A1 (en)	1996-08-08
CA2208780C (en)	2010-03-30
CN1173206A (zh)	1998-02-11
JP3638955B2 (ja)	2005-04-13
ATE219146T1 (de)	2002-06-15
EP0807185B9 (de)	2002-12-11
CN1113102C (zh)	2003-07-02

Publication	Publication Date	Title
ES2178699T3 (es)	2003-01-01	Preparaciones antitumorales que contienen un acido lipoteicoico procedente de streptococcus.
EP0454102A3 (en)	1992-01-02	Essential fatty acid compositions
GB9519661D0 (en)	1995-11-29	Fatty acid treatment
CY1112927T1 (el)	2016-04-13	Αντισωματα κατα της ανθρωπινης il-12
ATE66350T1 (de)	1991-09-15	Suessware und verfahren zur herstellung derselben.
ES551563A0 (es)	1987-12-01	Procedimiento para la preparacion de un suplemento mineral masticable
IL69930A0 (en)	1984-01-31	Oral mopidamol preparations and their production
DK0956013T3 (da)	2003-08-04	Farmaceutisk præparat indeholdende eicosapentaensyre og/eller stearidonsyre
IL107255A0 (en)	1994-01-25	Chewable pharmaceutical compositions
MY110734A (en)	1996-11-30	Improvements in or relating to dioic acids.
DE69620271D1 (de)	2002-05-02	Polyribosylribitol-phosphat enthaltende Haemophilus-influenzae-Typ-b-Impfstoffzubereitung und Verfahren zur deren Herstellung
DE3479189D1 (en)	1989-09-07	Pharmaceutical composition with special 1,2-diacyl-glycero-3-phosphocholines for the treatment of diseases of the stomach and the intestines
SI0785948T1 (en)	2003-08-31	Analogs of keratinocyte growth factor
CA2101648A1 (en)	1992-09-13	Polysaccharide-protein conjugates
FR2644788B1 (fr)	1995-02-03	Nouveaux steroides 3-ceto comportant une chaine en 17 amino-substituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
JPS5782322A (en)	1982-05-22	Novel immunostimulant sugar protein extracted from pneumonia bacillus,obtaining method, application as drug and composition containing same
CA2124605A1 (en)	1994-11-29	Prevention and improvement of medical symptoms caused by leucotriene b4
DE3470277D1 (en)	1988-05-11	Dietetic composition
IL111805A0 (en)	1995-01-24	Pharmaceutical compositions comprising dimeticone for the treatment of aphthae
EP0722339A4 (de)	2001-05-23	IMPFSTÄMME DER SEROGRUPPE 01 (CVD111) UND NICHT-01 (CVD112 UND CVD112RM) VON -i(VIBRIO CHOLERAE) UND METHODEN IHRER HERSTELLUNG
HUT52476A (en)	1990-07-28	Process for producing side chain unsaturated 1 alpha-hydroxy-d-vitamin homologues and pharmaceutical compositions comprising such compounds
DE69209486D1 (de)	1996-05-02	Stabilisierte pharmaceutische Zusammensetzung die nicht-glycozylierte, reduzierte rekombinante human IL-2 umfasst und Verfahren zu ihrer Herstellung
FR2658516B1 (fr)	1992-06-12	Nouveaux produits sterouides comportant un radical spiro en position 17, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
EA200000131A1 (ru)	2000-06-26	Иммуномодулирующая композиция на основе липидов
HUT74563A (en)	1997-01-28	Dextrane esters, process for producing them and their use for encasing and encapsulating medicaments