ATE219326T1 - Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation - Google Patents

Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation

Info

Publication number: ATE219326T1
Authority: AT; Austria
Prior art keywords: perfusion; preservation; range; organt; transplantation
Prior art date: 1998-11-10

Application number

AT99954071T

Other languages

English (en)

Inventor

Patrick Cozzone

Monique La Boiseraie Bernard

Original Assignee

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-10

Filing date

1999-11-05

Publication date

2002-07-15

1999-11-05 Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient

2002-07-15 Application granted granted Critical

2002-07-15 Publication of ATE219326T1 publication Critical patent/ATE219326T1/de

Links

230000010412 perfusion Effects 0.000 title abstract 2
238000004321 preservation Methods 0.000 title abstract 2
230000010410 reperfusion Effects 0.000 title 1
238000002054 transplantation Methods 0.000 title 1
OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
210000000056 organ Anatomy 0.000 abstract 2
239000004475 Arginine Substances 0.000 abstract 1
239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
229960005305 adenosine Drugs 0.000 abstract 1
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Environmental Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Dentistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT99954071T 1998-11-10 1999-11-05 Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation ATE219326T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9814132A FR2785501B1 (fr)	1998-11-10	1998-11-10	Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
PCT/FR1999/002711 WO2000027189A1 (fr)	1998-11-10	1999-11-05	Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes

Publications (1)

Publication Number	Publication Date
ATE219326T1 true ATE219326T1 (de)	2002-07-15

Family

ID=9532576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99954071T ATE219326T1 (de)	1998-11-10	1999-11-05	Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation

Country Status (7)

Country	Link
US (1)	US6524785B1 (de)
EP (1)	EP1047299B1 (de)
AT (1)	ATE219326T1 (de)
DE (1)	DE69901877T2 (de)
ES (1)	ES2178487T3 (de)
FR (1)	FR2785501B1 (de)
WO (1)	WO2000027189A1 (de)

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US8409846B2 (en)	1997-09-23	2013-04-02	The United States Of America As Represented By The Department Of Veteran Affairs	Compositions, methods and devices for maintaining an organ
GB0028414D0 (en)	2000-11-22	2001-01-03	Univ Leeds	Flush preservation solution
US20040170950A1 (en) *	2002-09-12	2004-09-02	Prien Samuel D.	Organ preservation apparatus and methods
US9289003B2 (en) *	2003-07-02	2016-03-22	Chr. Hansen A/S	Use of compounds involved in biosynthesis of nucleic acids as cryoprotective agents
EP1493806A1 (de) *	2003-07-02	2005-01-05	Chr. Hansen A/S	Verwendung von Verbindungen, welche in der Biosynthese von Nukleinsäuren involviert sind, als Gefrierschutz
US20050170019A1 (en) *	2003-10-22	2005-08-04	Fred Hutchinson Cancer Research Center	Methods, compositions and devices for inducing stasis in cells
US20050136125A1 (en) *	2003-10-22	2005-06-23	Roth Mark B.	Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
JP2007509163A (ja) *	2003-10-22	2007-04-12	フレッドハッチンソンキャンサーリサーチセンター	組織および臓器においてスタシスを誘導する方法、組成物、および装置
US20050142121A1 (en) *	2003-12-24	2005-06-30	Gold Joseph D.	System for improving acceptance of tissue grafts made from embryonic stem cells
US20050153271A1 (en) *	2004-01-13	2005-07-14	Wenrich Marshall S.	Organ preservation apparatus and methods
US9301519B2 (en) *	2004-10-07	2016-04-05	Transmedics, Inc.	Systems and methods for ex-vivo organ care
US12010987B2 (en)	2004-10-07	2024-06-18	Transmedics, Inc.	Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US8304181B2 (en)	2004-10-07	2012-11-06	Transmedics, Inc.	Method for ex-vivo organ care and for using lactate as an indication of donor organ status
NZ591524A (en) *	2004-10-07	2012-09-28	Transmedics Inc	Method for timing pulsatile flow of normothermic perfusate to the heart in ex-vivo organ care
US20060147429A1 (en) *	2004-12-30	2006-07-06	Paul Diamond	Facilitated cellular reconstitution of organs and tissues
US20060148080A1 (en) *	2004-12-30	2006-07-06	Paul Diamond	Methods for supporting and producing human cells and tissues in non-human mammal hosts
US20060160062A1 (en)	2005-01-14	2006-07-20	Young Lindon H	Perfusion and/or preservation solution for organs
US8822535B2 (en) *	2005-04-20	2014-09-02	Fred Hutchinson Cancer Research Center	Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms
US9078428B2 (en)	2005-06-28	2015-07-14	Transmedics, Inc.	Systems, methods, compositions and solutions for perfusing an organ
EP1948183B1 (de) *	2005-10-13	2013-12-18	Duke University	Zusammensetzungen zur behandlung und prävention von herzkrankheiten und anwendungsverfahren dafür
EP3677118A1 (de) *	2006-04-19	2020-07-08	Transmedics, Inc.	Systeme zur ex-vivo-organpflege
US20080145919A1 (en) *	2006-12-18	2008-06-19	Franklin Thomas D	Portable organ and tissue preservation apparatus, kit and methods
CN105123670B (zh) *	2007-02-17	2018-12-14	哈佛学院董事会	用于进行组织保存的组合物以及方法
US9457179B2 (en)	2007-03-20	2016-10-04	Transmedics, Inc.	Systems for monitoring and applying electrical currents in an organ perfusion system
US8420380B2 (en) *	2008-01-31	2013-04-16	Transmedics, Inc.	Systems and methods for ex vivo lung care
CA2715634A1 (en)	2008-02-15	2009-08-27	President And Fellows Of Harvard College	Blood substitute solution
US20090263780A1 (en) *	2008-04-17	2009-10-22	Yanming Wang	Organ preservation fluid
WO2011002926A2 (en)	2009-07-01	2011-01-06	The General Hospital Corporation	Isolated adult cells, artificial organs,rehabilitated organs, research rools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
US10575515B2 (en) *	2010-05-04	2020-03-03	The General Hospital Corporation	Methods and compositions for preserving tissues and organs
EP2704560B1 (de)	2011-04-14	2022-04-06	Transmedics, Inc.	Organpflegelösung zur maschinellen ex-vivo-perfusion von spenderlungen
US9119393B2 (en) *	2012-07-10	2015-09-01	Lifeline Scientific, Inc.	Organ transporter with tilt and/or shock sensing
WO2015138832A1 (en)	2014-03-13	2015-09-17	The General Hospital Corporation	Devices and methods to improve and assess viability of human livers
US10433539B2 (en)	2014-04-10	2019-10-08	Tevosol, Inc.	Composition and solution with controlled calcium ion level, and related method and use for reperfusion
BR112016023394B1 (pt)	2014-04-10	2021-09-21	Darren Freed	Composição cardioplégica e seu uso
US10076112B2 (en)	2014-06-02	2018-09-18	Transmedic, Inc.	Ex vivo organ care system
CN107105640B (zh) *	2014-10-24	2021-10-12	体沃索股份有限公司	具有控制的钙离子水平的新型组合物和溶液以及用于再灌注的相关方法和用途
WO2016090498A1 (en)	2014-12-12	2016-06-16	Freed Darren	Apparatus and method for organ perfusion
PL3277083T3 (pl)	2015-04-03	2025-05-26	Vivalyx Gmbh	Zastosowanie kompozycji do prezerwacji narządów w celu prezerwacji narządu lub jego części
EP3347084B1 (de)	2015-09-09	2020-11-11	Transmedics, Inc.	Aortenkanüle für ex-vivo-organpflegesystem
CA3025673A1 (en)	2016-05-30	2017-12-07	Tevosol, Inc.	Apparatus and method for ex vivo lung ventilation with a varying exterior pressure
US12058996B2 (en)	2017-06-14	2024-08-13	The General Hospital Corporation	High subzero cryopreservation
WO2019232268A1 (en)	2018-05-30	2019-12-05	Mustafa Korkut Uygun	Cryopreservation of tissues and organs
CN111937861B (zh) *	2020-08-17	2021-10-26	南昌大学第二附属医院	一种七氟烷缺血再灌注装置及使用方法

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4920044A (en) *	1988-11-08	1990-04-24	The Cleveland Clinic Foundation	Intracellular flush solution for preserving organs
US5290766A (en) *	1991-02-18	1994-03-01	The National Heart Foundation Of New Zealand	Cardioplegic compositions
US5407793A (en) *	1991-10-18	1995-04-18	University Of Pittsburgh Of The Commonwealth System Of Higher Education	An aqueous heart preservation and cardioplegia solution
CH686870A5 (fr) *	1992-09-18	1996-07-31	Pasteur Merieux Serums Vacc	Solution de perfusion, de conservation et de reperfusion d'organes.

1998
- 1998-11-10 FR FR9814132A patent/FR2785501B1/fr not_active Expired - Fee Related
1999
- 1999-11-05 EP EP99954071A patent/EP1047299B1/de not_active Expired - Lifetime
- 1999-11-05 AT AT99954071T patent/ATE219326T1/de not_active IP Right Cessation
- 1999-11-05 US US09/582,996 patent/US6524785B1/en not_active Expired - Fee Related
- 1999-11-05 WO PCT/FR1999/002711 patent/WO2000027189A1/fr not_active Ceased
- 1999-11-05 ES ES99954071T patent/ES2178487T3/es not_active Expired - Lifetime
- 1999-11-05 DE DE69901877T patent/DE69901877T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1047299A1 (de)	2000-11-02
DE69901877T2 (de)	2003-01-23
ES2178487T3 (es)	2002-12-16
WO2000027189A1 (fr)	2000-05-18
FR2785501B1 (fr)	2001-01-05
FR2785501A1 (fr)	2000-05-12
DE69901877D1 (de)	2002-07-25
EP1047299B1 (de)	2002-06-19
US6524785B1 (en)	2003-02-25

Legal Events

Date	Code	Title	Description
2002-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69901877D1 (de)	2002-07-25	Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation
SI1404811T1 (sl)	2009-04-30	Ogljikov monoksid izboljša rezultate pri presaditvi tkiva in organov ter prepreči apoptozo
ATE210373T1 (de)	2001-12-15	Kryokonservierung von kultivierten gewebeäquivalenten
DE69626204D1 (de)	2003-03-20	Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen
SE8804661D0 (sv)	1988-12-27	Perfusate for the preservation of organs
DE602005017707D1 (de)	2009-12-31	Verfahren zur Herstellung von Dipeptiden oder Dipeptidderivaten.
DE69530212D1 (de)	2003-05-08	Verfahren zur vorbereitung von organen auf die kryokonservierung
ZA89232B (en)	1990-06-27	Acylated uridine and cytidine and use thereof
BR9912662A (pt)	2001-06-05	Melhoria de função cardìaca por transplante de célula de ramo mesenquimal
MXPA02007137A (es)	2004-09-06	Fuente de tejido hepatico.
MX172905B (es)	1994-01-20	Composicion y metodo para mantener intacto un v aso sanguineo durante la criopreservacion
DE69912457D1 (de)	2003-12-04	Verlängerte lagerung roter blutzellen
DE3874019D1 (de)	1992-10-01	Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.
DE60100170D1 (de)	2003-05-15	Physiologisches medium für perfusion, konservierung und lagerung von isolierten zellen-, gewebe- und organproben
FR2523956B1 (de)	1985-05-24
NO982721D0 (no)	1998-06-12	Preserverende oppl°sning
ATA189793A (de)	2000-06-15	Lösung zur perfusion, konservierung und reperfusion von organen
MX9301535A (es)	1994-03-31	Material proteinaceo biologicamente activo aislado y purificado.
SE376710B (de)	1975-06-09
AU2003210768A8 (en)	2003-09-02	Polyglycerol and lactose compositions for the protection of living systems from states of reduced metabolism
ATE336166T1 (de)	2006-09-15	Lösungen für die lagerung und perfusion von organen für transplantationen
IT1251995B (it)	1995-05-27	Soluzioni di perfusione,di conservazione e di riperfusione d'organi
EA200000762A1 (ru)	2001-04-23	Способ для консервации органов или других тканей для трансплантации
ATE251455T1 (de)	2003-10-15	Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation
ATE258443T1 (de)	2004-02-15	Verwendung des proteins uk 114 zur verhinderung der abstossung eines transplantierten organs