ATE219489T1 - Verfahren zur herstellung von 5-carboxyphthalid - Google Patents

Verfahren zur herstellung von 5-carboxyphthalid

Info

Publication number: ATE219489T1
Authority: AT; Austria
Prior art keywords: carboxyphthalide; mixture; producing; isolating; heating
Prior art date: 2000-01-18

Application number

AT00203602T

Other languages

English (en)

Inventor

Asta Leone Dall

Umberto Casazza

Giovanni Cotticelli

Original Assignee

Norpharma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2000-10-17

Publication date

2002-07-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332721&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE219489(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-10-17 Application filed by Norpharma Spa filed Critical Norpharma Spa

2002-07-15 Application granted granted Critical

2002-07-15 Publication of ATE219489T1 publication Critical patent/ATE219489T1/de

Links

QTWUWCFGWYYRRL-UHFFFAOYSA-N 1-oxo-3h-2-benzofuran-5-carboxylic acid Chemical compound OC(=O)C1=CC=C2C(=O)OCC2=C1 QTWUWCFGWYYRRL-UHFFFAOYSA-N 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
KKEYFWRCBNTPAC-UHFFFAOYSA-N Terephthalic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
238000010438 heat treatment Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
HIFJUMGIHIZEPX-UHFFFAOYSA-N sulfuric acid;sulfur trioxide Chemical compound O=S(=O)=O.OS(O)(=O)=O HIFJUMGIHIZEPX-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Seasonings (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT00203602T 2000-01-18 2000-10-17 Verfahren zur herstellung von 5-carboxyphthalid ATE219489T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2000MI000050A IT1317729B1 (it)	2000-01-18	2000-01-18	Procedimento per la preparazione della 5-carbossiftalide.
US09/690,301 US6458973B1 (en)	2000-01-18	2000-10-17	Process for the preparation of 5-carboxyphthalide

Publications (1)

Publication Number	Publication Date
ATE219489T1 true ATE219489T1 (de)	2002-07-15

Family

ID=26332721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00203602T ATE219489T1 (de)	2000-01-18	2000-10-17	Verfahren zur herstellung von 5-carboxyphthalid

Country Status (21)

Country	Link
US (4)	US6458973B1 (de)
EP (2)	EP1118614B2 (de)
JP (1)	JP4558182B2 (de)
CN (1)	CN1184220C (de)
AT (1)	ATE219489T1 (de)
AU (1)	AU779581B2 (de)
BG (1)	BG65763B1 (de)
BR (1)	BR0107853A (de)
CA (1)	CA2397497C (de)
DE (1)	DE60000226T3 (de)
DK (1)	DK1118614T4 (de)
ES (1)	ES2178626T5 (de)
HK (1)	HK1042290B (de)
HU (1)	HUP0204187A3 (de)
IT (1)	IT1317729B1 (de)
MX (1)	MXPA02007031A (de)
PL (1)	PL356563A1 (de)
PT (1)	PT1118614E (de)
RO (1)	RO121737B1 (de)
WO (1)	WO2001053284A1 (de)
ZA (1)	ZA200205475B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR026063A1 (es) *	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
KR20020080485A (ko) *	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	5-치환 1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의단계적 알킬화
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CN1761659A (zh) *	2003-03-21	2006-04-19	H·隆德贝克有限公司	用于制备西酞普兰和依他普仑的中间体
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh)	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱
WO2006090409A1 (en) *	2005-02-28	2006-08-31	Kekule Pharma Ltd.,	An improved process for the preparation of 5 - carboxyphthalide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3607884A (en) *	1969-03-11	1971-09-21	Mobil Oil Corp	Preparation of 5-carboxyphthalide in liquid sodium trioxide
US3976751A (en) †	1974-10-21	1976-08-24	Allied Chemical Corporation	Stabilization of liquid sulfur trioxide
DE2630927A1 (de)	1976-07-09	1978-01-19	Basf Ag	Verfahren zur herstellung von phthalidcarbonsaeure-(5)
DE3605716A1 (de)	1986-02-22	1987-09-03	Henkel Kgaa	Verwendung von unloeslichen schmutzsammlern zur regenerierung von wasch- und reinigungsloesungen
SK283309B6 (sk) *	1997-07-08	2003-05-02	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
ES2189502T3 (es) *	1998-10-20	2003-07-01	Lundbeck & Co As H	Metodo para la prevencion de citalopram.
WO2001032643A1 (en)	1999-11-01	2001-05-10	H. Lundbeck A/S	Method for the preparation of 5-carboxyphthalide
AR026063A1 (es) *	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram

2000
- 2000-01-18 IT IT2000MI000050A patent/IT1317729B1/it active
- 2000-10-17 DE DE60000226T patent/DE60000226T3/de not_active Expired - Lifetime
- 2000-10-17 ES ES00203602T patent/ES2178626T5/es not_active Expired - Lifetime
- 2000-10-17 US US09/690,301 patent/US6458973B1/en not_active Expired - Fee Related
- 2000-10-17 EP EP00203602A patent/EP1118614B2/de not_active Expired - Lifetime
- 2000-10-17 DK DK00203602.8T patent/DK1118614T4/da active
- 2000-10-17 PT PT00203602T patent/PT1118614E/pt unknown
- 2000-10-17 AT AT00203602T patent/ATE219489T1/de not_active IP Right Cessation
- 2000-12-07 JP JP2000372224A patent/JP4558182B2/ja not_active Expired - Lifetime
2001
- 2001-01-17 RO ROA200200989A patent/RO121737B1/ro unknown
- 2001-01-17 CN CNB018038484A patent/CN1184220C/zh not_active Expired - Lifetime
- 2001-01-17 MX MXPA02007031A patent/MXPA02007031A/es active IP Right Grant
- 2001-01-17 BR BR0107853-4A patent/BR0107853A/pt not_active Application Discontinuation
- 2001-01-17 AU AU26798/01A patent/AU779581B2/en not_active Revoked
- 2001-01-17 PL PL01356563A patent/PL356563A1/xx not_active IP Right Cessation
- 2001-01-17 WO PCT/EP2001/000617 patent/WO2001053284A1/en not_active Ceased
- 2001-01-17 EP EP01901181A patent/EP1187822A1/de not_active Withdrawn
- 2001-01-17 CA CA2397497A patent/CA2397497C/en not_active Expired - Fee Related
- 2001-01-17 HU HU0204187A patent/HUP0204187A3/hu unknown
2002
- 2002-01-25 HK HK02100631.3A patent/HK1042290B/en not_active IP Right Cessation
- 2002-07-09 ZA ZA200205475A patent/ZA200205475B/xx unknown
- 2002-07-16 BG BG106925A patent/BG65763B1/bg unknown
- 2002-08-23 US US10/227,038 patent/US6703516B2/en not_active Expired - Fee Related
2004
- 2004-03-08 US US10/796,336 patent/US20040171851A1/en not_active Abandoned
2007
- 2007-10-22 US US11/975,842 patent/US20080249319A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20030009038A1 (en)	2003-01-09
ES2178626T3 (es)	2003-01-01
PT1118614E (pt)	2002-11-29
DE60000226T3 (de)	2012-02-16
HUP0204187A3 (en)	2005-05-30
HK1042290A1 (en)	2002-08-09
DK1118614T4 (da)	2011-06-27
EP1187822A1 (de)	2002-03-20
DE60000226T2 (de)	2003-03-06
HK1042290B (en)	2003-07-18
EP1118614B1 (de)	2002-06-19
IT1317729B1 (it)	2003-07-15
US20080249319A1 (en)	2008-10-09
US6703516B2 (en)	2004-03-09
HUP0204187A2 (hu)	2003-03-28
WO2001053284A1 (en)	2001-07-26
US20040171851A1 (en)	2004-09-02
MXPA02007031A (es)	2004-09-06
CA2397497C (en)	2010-07-06
BG65763B1 (bg)	2009-10-30
PL356563A1 (en)	2004-06-28
BR0107853A (pt)	2002-10-29
EP1118614A3 (de)	2001-10-24
CN1184220C (zh)	2005-01-12
ITMI20000050A1 (it)	2001-07-18
DE60000226D1 (de)	2002-07-25
ITMI20000050A0 (it)	2000-01-18
JP4558182B2 (ja)	2010-10-06
BG106925A (bg)	2004-01-30
EP1118614A2 (de)	2001-07-25
CN1406236A (zh)	2003-03-26
ES2178626T5 (es)	2011-06-02
CA2397497A1 (en)	2001-07-26
US6458973B1 (en)	2002-10-01
DK1118614T3 (da)	2002-10-14
AU2679801A (en)	2001-07-31
AU779581B2 (en)	2005-01-27
EP1118614B2 (de)	2011-03-09
RO121737B1 (ro)	2008-03-28
ZA200205475B (en)	2003-12-31
JP2001206881A (ja)	2001-07-31

Legal Events

Date

Code

Title

Description

2003-09-15

EEIH

Change in the person of patent owner

2003-11-15

UEP

Publication of translation of european patent specification

Ref document number: 1118614

Country of ref document: EP

2011-09-15

RER

Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE219489T1 (de)	2002-07-15	Verfahren zur herstellung von 5-carboxyphthalid
DE69119234D1 (de)	1996-06-05	Verfahren zur herstellung von reiner hydroxyessigsäure
ATE215060T1 (de)	2002-04-15	Verfahren zur herstellung von rhein und seinen diacylderivaten
TR200100191T2 (tr)	2001-05-21	Karma ksilenlerden saflaştırılmış terftalik asit ve izoftalik asit hazırlamak için yöntem
ATE221062T1 (de)	2002-08-15	Verfahren zur herstellung von thioxanthon und derivaten davon
ATE276998T1 (de)	2004-10-15	Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
ATE8142T1 (de)	1984-07-15	Verfahren zur herstellung von isosorbid-5-nitrat.
EP1350786A4 (de)	2005-12-14	Verfahren zur herstellung von dicarbonsäuren
ATE302749T1 (de)	2005-09-15	Verfahren zur herstellung von 5-aminosalicylsäure
ATE145393T1 (de)	1996-12-15	Verfahren zur herstellung von 2-chloro- und 2,6- dichloranilinen
DE3861886D1 (de)	1991-04-11	Verfahren zur herstellung von maleinsaeuredimethylester.
ATE97661T1 (de)	1993-12-15	Herstellung von pyridazinon.
ATE86597T1 (de)	1993-03-15	Verfahren zur stereoselektiven herstellung von z- 1,2-diaryl-allyl-chloriden und deren umsetzung zu azolylmethyloxiranen sowie neue zwischenprodukte.
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ATE365152T1 (de)	2007-07-15	Verfahren zur herstellung fluorierter benzoesäuren
ATE139765T1 (de)	1996-07-15	Verfahren zur herstellung von halogenanthranilsäuren
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EP1067107A4 (de)	2005-05-11	Verfahren zur herstellung von ketoisophoronderivaten and geräte dafür
DE3878700D1 (de)	1993-04-08	Verfahren zur herstellung von thiazolobenzimidazolen und zwischenprodukte.
DE69915965D1 (de)	2004-05-06	Stereoselektives Verfahren zur Herstellung vom 22R Epimer von Budesonid
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DE69804919D1 (de)	2002-05-23	Verfahren zur Herstellung von 5-isopropyluracil
DE3584528D1 (de)	1991-12-05	Katalytisches verfahren zur herstellung von amiden.
ATE121715T1 (de)	1995-05-15	Verfahren zur herstellung von 3,3',4,4'- tetramethyldiphenylmethan.
ATE146452T1 (de)	1997-01-15	Verfahren zur herstellung von hydroxyphenylessigsäuren