ATE220419T1 - Verfahren zur herstellung von cis-3-hydroxy-l- prolin - Google Patents
Verfahren zur herstellung von cis-3-hydroxy-l- prolinInfo
- Publication number
- ATE220419T1 ATE220419T1 AT96905023T AT96905023T ATE220419T1 AT E220419 T1 ATE220419 T1 AT E220419T1 AT 96905023 T AT96905023 T AT 96905023T AT 96905023 T AT96905023 T AT 96905023T AT E220419 T1 ATE220419 T1 AT E220419T1
- Authority
- AT
- Austria
- Prior art keywords
- proline
- hydroxy
- producing cis
- producing
- hydroxylases
- Prior art date
Links
- BJBUEDPLEOHJGE-DMTCNVIQSA-N cis-3-hydroxy-L-proline Chemical compound O[C@@H]1CC[NH2+][C@@H]1C([O-])=O BJBUEDPLEOHJGE-DMTCNVIQSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 2
- 229930182821 L-proline Natural products 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229960002429 proline Drugs 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/24—Proline; Hydroxyproline; Histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4698795 | 1995-03-07 | ||
| PCT/JP1996/000558 WO1996027668A1 (en) | 1995-03-07 | 1996-03-07 | PROCESS FOR PRODUCING cis-3-HYDROXY-L-PROLINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE220419T1 true ATE220419T1 (de) | 2002-07-15 |
Family
ID=12762566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96905023T ATE220419T1 (de) | 1995-03-07 | 1996-03-07 | Verfahren zur herstellung von cis-3-hydroxy-l- prolin |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0771876B1 (de) |
| JP (1) | JP3781776B2 (de) |
| KR (1) | KR100460580B1 (de) |
| CN (1) | CN1144876C (de) |
| AT (1) | ATE220419T1 (de) |
| CA (1) | CA2189675C (de) |
| DE (1) | DE69622239T2 (de) |
| ES (1) | ES2177762T3 (de) |
| WO (1) | WO1996027668A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5697327B2 (ja) * | 2009-11-09 | 2015-04-08 | 協和発酵バイオ株式会社 | シス−ヒドロキシ−ｌ−プロリンの製造方法 |
| CN109232351A (zh) * | 2018-10-19 | 2019-01-18 | 武汉恒和达生物医药有限公司 | 一种顺式-3-羟基-l-脯氨酸的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100356927B1 (ko) * | 1993-09-07 | 2003-01-24 | 교와 핫꼬 고교 가부시끼가이샤 | 시스-3-히드록시-l-프롤린의제조법 |
| CA2131776C (en) * | 1994-04-05 | 2002-04-23 | Akio Ozaki | Process for producing cis-3-hydroxy-l-proline |
-
1996
- 1996-03-07 KR KR1019960706293A patent/KR100460580B1/ko not_active Expired - Lifetime
- 1996-03-07 WO PCT/JP1996/000558 patent/WO1996027668A1/ja not_active Ceased
- 1996-03-07 CA CA002189675A patent/CA2189675C/en not_active Expired - Lifetime
- 1996-03-07 ES ES96905023T patent/ES2177762T3/es not_active Expired - Lifetime
- 1996-03-07 CN CNB961903554A patent/CN1144876C/zh not_active Expired - Lifetime
- 1996-03-07 JP JP52676996A patent/JP3781776B2/ja not_active Expired - Lifetime
- 1996-03-07 AT AT96905023T patent/ATE220419T1/de not_active IP Right Cessation
- 1996-03-07 DE DE69622239T patent/DE69622239T2/de not_active Expired - Lifetime
- 1996-03-07 EP EP96905023A patent/EP0771876B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1144876C (zh) | 2004-04-07 |
| EP0771876A1 (de) | 1997-05-07 |
| DE69622239D1 (de) | 2002-08-14 |
| CN1150822A (zh) | 1997-05-28 |
| KR100460580B1 (ko) | 2005-01-15 |
| ES2177762T3 (es) | 2002-12-16 |
| EP0771876A4 (de) | 1999-06-02 |
| KR970702920A (ko) | 1997-06-10 |
| EP0771876B1 (de) | 2002-07-10 |
| CA2189675A1 (en) | 1996-09-08 |
| JP3781776B2 (ja) | 2006-05-31 |
| HK1000713A1 (en) | 2002-10-11 |
| DE69622239T2 (de) | 2003-03-27 |
| WO1996027668A1 (en) | 1996-09-12 |
| CA2189675C (en) | 2007-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |