ATE220898T1 - Nifedipinzubereitung mit langanhaltender freisetzung - Google Patents

Nifedipinzubereitung mit langanhaltender freisetzung

Info

Publication number
ATE220898T1
ATE220898T1 AT96118311T AT96118311T ATE220898T1 AT E220898 T1 ATE220898 T1 AT E220898T1 AT 96118311 T AT96118311 T AT 96118311T AT 96118311 T AT96118311 T AT 96118311T AT E220898 T1 ATE220898 T1 AT E220898T1
Authority
AT
Austria
Prior art keywords
hours
long
nifedipine
lasting release
dissolution test
Prior art date
Application number
AT96118311T
Other languages
English (en)
Inventor
Takaaki Nishioka
Kenji Kuratani
Haruo Kanasaki
Helmut Dr Luchtenberg
Ulrich Dr Tenter
Andreas Dr Ohm
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE220898T1 publication Critical patent/ATE220898T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
AT96118311T 1995-11-28 1996-11-15 Nifedipinzubereitung mit langanhaltender freisetzung ATE220898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33121795A JP3220373B2 (ja) 1995-11-28 1995-11-28 持続性ニフエジピン製剤

Publications (1)

Publication Number Publication Date
ATE220898T1 true ATE220898T1 (de) 2002-08-15

Family

ID=18241212

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96118311T ATE220898T1 (de) 1995-11-28 1996-11-15 Nifedipinzubereitung mit langanhaltender freisetzung

Country Status (14)

Country Link
US (1) US5861173A (de)
EP (1) EP0776660B1 (de)
JP (1) JP3220373B2 (de)
KR (1) KR970025607A (de)
AT (1) ATE220898T1 (de)
AU (1) AU709887B2 (de)
CA (1) CA2191178C (de)
DE (1) DE69622510T2 (de)
ES (1) ES2180683T3 (de)
IL (1) IL119684A (de)
MX (1) MX9605646A (de)
NZ (1) NZ299818A (de)
SG (1) SG48492A1 (de)
ZA (1) ZA969945B (de)

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IN190974B (de) * 1999-09-10 2003-09-06 Ranbaxy Lab Ltd
WO2001045668A2 (en) * 1999-12-20 2001-06-28 Schering Corporation Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
PT1251832E (pt) * 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
JP4637338B2 (ja) * 2000-09-22 2011-02-23 大塚製薬株式会社 シロスタゾール有核錠
SE0004671D0 (sv) 2000-12-15 2000-12-15 Amarin Dev Ab Pharmaceutical formulation
KR100685945B1 (ko) 2000-12-29 2007-02-23 엘지.필립스 엘시디 주식회사 액정표시장치 및 그 제조방법
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US6987123B2 (en) 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
JP4817562B2 (ja) * 2001-09-26 2011-11-16 東和薬品株式会社 長時間持続型ニフエジピン有核錠
CA2447984A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Dosage forms having an inner core and outer shell with different shapes
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
AU2003227472A1 (en) * 2002-03-27 2003-10-08 Bayer Aktiengesellschaft Downsized core tablet containing nifedipine
DE60228939D1 (de) * 2002-05-21 2008-10-30 Watson Lab Inc Pharmazeutische Zusammensetzung mit verzögerter Freisetzung
JP4563642B2 (ja) * 2002-05-31 2010-10-13 ワトソン ラボラトリーズ、インコーポレイテッド 医薬製剤
CA2519208A1 (en) * 2003-03-17 2004-09-30 Takeda Pharmaceutical Company Limited Controlled release composition
JP4933033B2 (ja) * 2003-03-17 2012-05-16 武田薬品工業株式会社 放出制御組成物
CN102525993B (zh) 2003-04-24 2017-04-12 佳高泰克有限公司 具有限定内核几何形状的缓释片剂
US20040219210A1 (en) * 2003-05-01 2004-11-04 Jian-Hwa Guo Controlled release solid dosage nifedipine formulations
US20040241234A1 (en) * 2003-06-02 2004-12-02 Alpharma, Inc. Controlled release press-coated formulations of water-soluble active agents
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
TW200526274A (en) * 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US20060024368A1 (en) * 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
US7470293B2 (en) * 2004-10-29 2008-12-30 Idatech, Llc Feedstock delivery systems, fuel processing systems, and hydrogen generation assemblies including the same
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
DE102005031577A1 (de) 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
US8637078B2 (en) * 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
KR100774250B1 (ko) 2006-04-14 2007-11-07 넨시스(주) 1,4-디히드로피리딘 유도체 용출 제어형 과립제, 이의 정제및 이의 제조방법
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
AR066862A1 (es) * 2007-06-11 2009-09-16 Procter & Gamble Particula de suministro que contiene agentes beneficos
JP5545952B2 (ja) 2007-08-31 2014-07-09 第一三共株式会社 徐放性製剤及びその製造方法
JP5351490B2 (ja) * 2007-10-25 2013-11-27 バイエル薬品株式会社 ニフェジピン含有有核錠剤およびその製法
US20090285889A1 (en) * 2008-05-14 2009-11-19 Capricom Pharma Inc. Modified release formulations of dihydropyridine compounds and methods of making same
DE102008059206A1 (de) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
US8968779B2 (en) 2010-06-16 2015-03-03 Teijin Pharma Limited Controlled release coat-core tablet
JP6504163B2 (ja) * 2014-06-02 2019-04-24 ニプロ株式会社 レーザー印刷用錠剤及びその製造方法
JP6925969B2 (ja) * 2015-02-09 2021-08-25 エンテラ バイオ エルティーディー． 医薬組成物
WO2017111178A1 (en) 2015-12-24 2017-06-29 Takeda Pharmaceutical Company Limited Solid preparation
SG11201901070YA (en) 2016-08-17 2019-03-28 Entera Bio Ltd Formulations for oral administration of active agents
CN115192538B (zh) * 2022-08-02 2023-09-15 沈阳信康药物研究有限公司 一种压制包衣型硝苯地平缓释片及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033919A1 (de) 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
NO883326L (no) * 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin

Also Published As

Publication number Publication date
DE69622510D1 (de) 2002-08-29
IL119684A (en) 2000-09-28
EP0776660A3 (de) 1998-01-21
AU709887B2 (en) 1999-09-09
JP3220373B2 (ja) 2001-10-22
JPH09143073A (ja) 1997-06-03
SG48492A1 (en) 1998-04-17
CA2191178A1 (en) 1997-05-29
EP0776660A2 (de) 1997-06-04
NZ299818A (en) 1998-08-26
CA2191178C (en) 2005-10-04
DE69622510T2 (de) 2002-11-07
IL119684A0 (en) 1997-02-18
US5861173A (en) 1999-01-19
KR970025607A (ko) 1997-06-24
MX9605646A (es) 1997-06-28
ES2180683T3 (es) 2003-02-16
ZA969945B (en) 1997-06-23
AU7196096A (en) 1997-06-05
EP0776660B1 (de) 2002-07-24

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties