ATE221070T1 - Verfahren zur herstelung von pirlindolehydrochlorid - Google Patents
Verfahren zur herstelung von pirlindolehydrochloridInfo
- Publication number
- ATE221070T1 ATE221070T1 AT00107836T AT00107836T ATE221070T1 AT E221070 T1 ATE221070 T1 AT E221070T1 AT 00107836 T AT00107836 T AT 00107836T AT 00107836 T AT00107836 T AT 00107836T AT E221070 T1 ATE221070 T1 AT E221070T1
- Authority
- AT
- Austria
- Prior art keywords
- pirlindolehydrochloride
- producing
- methyl
- formula
- hydrochloride
- Prior art date
Links
- IWVRVEIKCBFZNF-UHFFFAOYSA-N LSM-1636 Chemical compound C1CNC2CCCC3=C2N1C1=CC=C(C)C=C13 IWVRVEIKCBFZNF-UHFFFAOYSA-N 0.000 title abstract 2
- 229950002220 pirlindole Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- BYKOLWPLPKIPBB-UHFFFAOYSA-N N-(2-chloroethyl)-6-methyl-2,3,4,9-tetrahydrocarbazol-1-imine hydrochloride Chemical compound Cl.Cc1ccc2[nH]c3c(CCCC3=NCCCl)c2c1 BYKOLWPLPKIPBB-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000802A IT1312539B1 (it) | 1999-04-16 | 1999-04-16 | Processo per la preparazione del pirlindolo cloridrato. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE221070T1 true ATE221070T1 (de) | 2002-08-15 |
Family
ID=11382759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00107836T ATE221070T1 (de) | 1999-04-16 | 2000-04-12 | Verfahren zur herstelung von pirlindolehydrochlorid |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1044976B1 (de) |
| AT (1) | ATE221070T1 (de) |
| DE (1) | DE60000274T2 (de) |
| ES (1) | ES2180483T3 (de) |
| HU (1) | HUP0001558A3 (de) |
| IT (1) | IT1312539B1 (de) |
| PL (1) | PL339641A1 (de) |
| PT (1) | PT1044976E (de) |
| RU (1) | RU2249592C2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6051378B2 (ja) * | 2011-05-02 | 2016-12-27 | 国立大学法人 熊本大学 | 幹細胞からインスリン産生細胞への分化誘導を促進する低分子化合物および該化合物を用いた幹細胞からインスリン産生細胞への分化誘導方法 |
| CN102952089B (zh) * | 2012-10-19 | 2015-07-08 | 江苏省农用激素工程技术研究中心有限公司 | 苯嗪草酮的制备方法 |
| CN104774208A (zh) * | 2015-04-24 | 2015-07-15 | 南京靖龙药物研发有限公司 | 一种氘标记吡吲哚盐酸盐的制备方法 |
| EP3392251A1 (de) * | 2017-04-21 | 2018-10-24 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Verfahren für das herstellung von pirlindoleenantiomere und ihre sälze |
| EP3392250A1 (de) * | 2017-04-21 | 2018-10-24 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Verfahren für das herstellung des pyrazinrings für die synthese der derivate der pyrazinocarbazole |
| CN110950873A (zh) * | 2019-12-10 | 2020-04-03 | 河南大学 | 坡尔吲哚的合成新方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2132514A1 (en) * | 1971-04-06 | 1972-11-24 | Inst Im Sergo | 1,10-trimethylene-8-methyl-tetrahydropyrazin - anti-depressant |
-
1999
- 1999-04-16 IT IT1999MI000802A patent/IT1312539B1/it active
-
2000
- 2000-04-12 AT AT00107836T patent/ATE221070T1/de not_active IP Right Cessation
- 2000-04-12 EP EP00107836A patent/EP1044976B1/de not_active Expired - Lifetime
- 2000-04-12 ES ES00107836T patent/ES2180483T3/es not_active Expired - Lifetime
- 2000-04-12 DE DE60000274T patent/DE60000274T2/de not_active Expired - Fee Related
- 2000-04-12 PT PT00107836T patent/PT1044976E/pt unknown
- 2000-04-13 PL PL00339641A patent/PL339641A1/xx not_active Application Discontinuation
- 2000-04-14 RU RU2000109633/04A patent/RU2249592C2/ru not_active IP Right Cessation
- 2000-04-14 HU HU0001558A patent/HUP0001558A3/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI990802A1 (it) | 2000-10-16 |
| HUP0001558A2 (hu) | 2001-04-28 |
| HUP0001558A3 (en) | 2003-08-28 |
| PL339641A1 (en) | 2000-10-23 |
| EP1044976A1 (de) | 2000-10-18 |
| EP1044976B1 (de) | 2002-07-24 |
| PT1044976E (pt) | 2002-12-31 |
| RU2249592C2 (ru) | 2005-04-10 |
| HU0001558D0 (en) | 2000-06-28 |
| DE60000274D1 (de) | 2002-08-29 |
| ES2180483T3 (es) | 2003-02-16 |
| IT1312539B1 (it) | 2002-04-22 |
| DE60000274T2 (de) | 2003-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |