ATE221875T1 - Vitamin d analoge verbindungen - Google Patents

Vitamin d analoge verbindungen

Info

Publication number: ATE221875T1
Authority: AT; Austria
Prior art keywords: stands; alkyl radical; aryl; hydrogen; formula
Prior art date: 1996-06-04

Application number

AT97924929T

Other languages

English (en)

Inventor

Claus Aage Bretting

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-04

Filing date

1997-05-15

Publication date

2002-08-15

1997-05-15 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE221875T1 publication Critical patent/ATE221875T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
230000004069 differentiation Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Tropical Medicine & Parasitology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)

AT97924929T 1996-06-04 1997-05-15 Vitamin d analoge verbindungen ATE221875T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9611603.3A GB9611603D0 (en)	1996-06-04	1996-06-04	Chemical compounds
PCT/DK1997/000225 WO1997046522A1 (en)	1996-06-04	1997-05-15	Novel vitamin d analogues

Publications (1)

Publication Number	Publication Date
ATE221875T1 true ATE221875T1 (de)	2002-08-15

Family

ID=10794707

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97924929T ATE221875T1 (de)	1996-06-04	1997-05-15	Vitamin d analoge verbindungen

Country Status (17)

Country	Link
US (1)	US6197982B1 (de)
EP (1)	EP0906276B1 (de)
JP (1)	JP2000511894A (de)
CN (1)	CN1217926C (de)
AT (1)	ATE221875T1 (de)
AU (1)	AU714223B2 (de)
CZ (1)	CZ296255B6 (de)
DE (1)	DE69714590T2 (de)
DK (1)	DK0906276T3 (de)
ES (1)	ES2179343T3 (de)
GB (1)	GB9611603D0 (de)
NZ (1)	NZ332237A (de)
PL (1)	PL186804B1 (de)
PT (1)	PT906276E (de)
RO (1)	RO120133B1 (de)
RU (1)	RU2165413C2 (de)
WO (1)	WO1997046522A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20090098065A1 (en) *	2000-01-11	2009-04-16	Avikam Harel	Composition and methods for the treatment of skin disorders
US7351869B2 (en) *	2002-11-18	2008-04-01	Teva Pharmaceutical Industries Ltd	Crystallization method for purification of calcipotriene
EP1768662A2 (de)	2004-06-24	2007-04-04	Novartis Vaccines and Diagnostics, Inc.	Immunstimulatoren kleiner moleküle und assays für deren nachweis
BRPI0715636A2 (pt) *	2006-08-29	2013-07-02	Teva Pharma	composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo
US8377913B2 (en) *	2007-11-20	2013-02-19	Abbvie Inc.	Vitamin D receptor activators and methods of making
SG173119A1 (en) *	2009-01-27	2011-08-29	Berg Biosystems Llc	Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
MX366076B (es)	2009-08-14	2019-06-27	Berg Llc	Vitamina d3 y analogos de la misma para tratar alopecia.
MX2012007225A (es) *	2009-12-22	2012-07-30	Leo Pharma As	Composicion farmaceutica que comprende mezcla de solventes y derivado o analogo de vitamina d.
RU2560677C2 (ru) *	2009-12-22	2015-08-20	Лео Фарма А/С	Кожная композиция, включающая аналог витамина d и смесь растворителя и поверхностно-активных веществ
DK2360145T3 (da) *	2010-01-26	2012-07-09	Hybrigenics Sa	Hidtil ukendt fremgangsmåde til isomerisering af kondenserede bicykliske strukturer og fremstilling af D-vitaminanaloger, der omfatter disse
JP5738307B2 (ja) *	2010-10-25	2015-06-24	帝人ファーマ株式会社	２３−イン−ビタミンｄ３誘導体
SG10201709894RA (en)	2013-05-29	2018-01-30	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d
AU2016234988B2 (en)	2015-10-02	2018-08-02	Lg Electronics Inc.	Washing machine
US20170096769A1 (en)	2015-10-02	2017-04-06	Lg Electronics Inc.	Method for controlling washing machine
AU2016234990B2 (en)	2015-10-02	2018-12-06	Lg Electronics Inc.	Washing machine and method for controlling the same
CN114728874B (zh) *	2019-11-27	2024-04-26	研成精密化学株式会社	用于制备马沙骨化醇的方法及用于其的中间体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU688125A3 (ru) *	1974-12-09	1979-09-25	Тейдзин Лимитед (Фирма)	Способ получени 1 , 24/ /диокси-холекальциферола или 1 , 24 / /-диоксихолекальциферола или их производных
EP0296800B1 (de) *	1987-06-23	1991-10-16	Yamanouchi Pharmaceutical Co. Ltd.	Vitamin D3-Derivate
GB9206648D0 (en)	1992-03-26	1992-05-06	Leo Pharm Prod Ltd	Chemical compounds
GB9223061D0 (en) *	1992-11-04	1992-12-16	Leo Pharm Prod Ltd	Chemical compounds
US5552392A (en)	1993-11-03	1996-09-03	Wisconsin Alumni Research Foundation	Method of treating hypoparathyroidism with (20S) vitamin D compounds

1996
- 1996-06-04 GB GBGB9611603.3A patent/GB9611603D0/en active Pending
1997
- 1997-05-15 CZ CZ0397198A patent/CZ296255B6/cs not_active IP Right Cessation
- 1997-05-15 EP EP97924929A patent/EP0906276B1/de not_active Expired - Lifetime
- 1997-05-15 RO RO98-01607A patent/RO120133B1/ro unknown
- 1997-05-15 PT PT97924929T patent/PT906276E/pt unknown
- 1997-05-15 NZ NZ332237A patent/NZ332237A/xx not_active IP Right Cessation
- 1997-05-15 ES ES97924929T patent/ES2179343T3/es not_active Expired - Lifetime
- 1997-05-15 JP JP10500106A patent/JP2000511894A/ja not_active Ceased
- 1997-05-15 DK DK97924929T patent/DK0906276T3/da active
- 1997-05-15 CN CN971950202A patent/CN1217926C/zh not_active Expired - Fee Related
- 1997-05-15 AU AU30256/97A patent/AU714223B2/en not_active Ceased
- 1997-05-15 AT AT97924929T patent/ATE221875T1/de active
- 1997-05-15 PL PL97329941A patent/PL186804B1/pl not_active IP Right Cessation
- 1997-05-15 US US09/202,200 patent/US6197982B1/en not_active Expired - Fee Related
- 1997-05-15 RU RU98121401/04A patent/RU2165413C2/ru not_active IP Right Cessation
- 1997-05-15 WO PCT/DK1997/000225 patent/WO1997046522A1/en not_active Ceased
- 1997-05-15 DE DE69714590T patent/DE69714590T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HK1019733A1 (en)	2000-02-25
PL186804B1 (pl)	2004-02-27
EP0906276B1 (de)	2002-08-07
JP2000511894A (ja)	2000-09-12
DE69714590D1 (de)	2002-09-12
RU2165413C2 (ru)	2001-04-20
ES2179343T3 (es)	2003-01-16
DE69714590T2 (de)	2003-04-24
RO120133B1 (ro)	2005-09-30
GB9611603D0 (en)	1996-08-07
PL329941A1 (en)	1999-04-26
CN1217926C (zh)	2005-09-07
NZ332237A (en)	2000-07-28
DK0906276T3 (da)	2002-12-02
AU3025697A (en)	1998-01-05
EP0906276A1 (de)	1999-04-07
WO1997046522A1 (en)	1997-12-11
US6197982B1 (en)	2001-03-06
CZ296255B6 (cs)	2006-02-15
AU714223B2 (en)	1999-12-23
CZ397198A3 (cs)	1999-03-17
PT906276E (pt)	2002-12-31
CN1219928A (zh)	1999-06-16

Legal Events

Date

Code

Title

Description

2003-05-15

UEP

Publication of translation of european patent specification

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Publication	Publication Date	Title
DE69714590D1 (de)	2002-09-12	Vitamin d analoge verbindungen
KR100268543B1 (en)	2000-10-16	Novel vitamin d analogues, and the process for preparing thereof
NO972156L (no)	1997-07-09	2-cyanacrylsyre-estere
DK1026147T3 (da)	2004-03-22	Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
DE69308852D1 (de)	1997-04-17	Vitamin d derivate
YU108791A (sh)	1994-01-20	Pirazolopirimidinon antianginalna jedinjenja
FI956108A0 (fi)	1995-12-19	Uudet D-vitamiinianalogit
DE69012351D1 (de)	1994-10-13	Neue Zwischenprodukte, ihre Herstellung und Verwendung.
GR880100208A (en)	1989-01-31	Preparation method of new aminotetrahydro-5,6,7,8,naphtho (2,3b) furane
ATE216361T1 (de)	2002-05-15	Vitamin d derivate
AU626095B2 (en)	1992-07-23	Hydroxyalkane carboxylic acid derivatives, their production and use
DE69608701D1 (de)	2000-07-06	Vitamin d analoge
AU543519B2 (en)	1985-04-26	New peptide amides and process for their manufacture
ATE8633T1 (de)	1984-08-15	Vinyl-3-cephalosporinverbindungen und ihre herstellung.